ATE120738T1 - 2,4-diamino-pyrimidin-3-oxid-derivate und deren verwendung bei der behandlung und zur verhütung von haarfall. - Google Patents

2,4-diamino-pyrimidin-3-oxid-derivate und deren verwendung bei der behandlung und zur verhütung von haarfall.

Info

Publication number
ATE120738T1
ATE120738T1 AT89402002T AT89402002T ATE120738T1 AT E120738 T1 ATE120738 T1 AT E120738T1 AT 89402002 T AT89402002 T AT 89402002T AT 89402002 T AT89402002 T AT 89402002T AT E120738 T1 ATE120738 T1 AT E120738T1
Authority
AT
Austria
Prior art keywords
prevention
treatment
oxide derivatives
diamino
pyrimidine
Prior art date
Application number
AT89402002T
Other languages
English (en)
Inventor
Michel Hocquaux
Jacqueline Dumats
Quintino Gaetani
Original Assignee
Oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oreal filed Critical Oreal
Application granted granted Critical
Publication of ATE120738T1 publication Critical patent/ATE120738T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
AT89402002T 1988-08-01 1989-07-12 2,4-diamino-pyrimidin-3-oxid-derivate und deren verwendung bei der behandlung und zur verhütung von haarfall. ATE120738T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU87308A LU87308A1 (fr) 1988-08-01 1988-08-01 Nouveaux derives de diamino-2,4 pyrimidine oxyde-3 et leur utilisation pour le traitement et la prevention de la chute des cheveux

Publications (1)

Publication Number Publication Date
ATE120738T1 true ATE120738T1 (de) 1995-04-15

Family

ID=19731083

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89402002T ATE120738T1 (de) 1988-08-01 1989-07-12 2,4-diamino-pyrimidin-3-oxid-derivate und deren verwendung bei der behandlung und zur verhütung von haarfall.

Country Status (8)

Country Link
US (1) US4973474A (de)
EP (1) EP0356271B1 (de)
JP (1) JP2669903B2 (de)
AT (1) ATE120738T1 (de)
CA (1) CA1340445C (de)
DE (1) DE68922044T2 (de)
ES (1) ES2070186T3 (de)
LU (1) LU87308A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5214041A (en) * 1989-06-12 1993-05-25 Shiseido Company Ltd. Hair revitalizing tonic composition
ATE110718T1 (de) * 1989-07-12 1994-09-15 Oreal Halogenierte pyrimidin-3-oxid-derivate, deren verwendung für die behandlung und die verhütung von haarausfall und für die wachstumsförderung von haaren.
FR2662607B1 (fr) * 1990-05-30 1992-08-28 Oreal Composition destinee a etre utilisee pour freiner la chute des cheveux et pour induire et stimuler leur croissance, contenant des derives d'alkyl-2 amino-4 (ou dialkyl-2-4) pyrimidine oxyde-3 .
FR2663327B1 (fr) * 1990-06-19 1992-09-25 Oreal Nouveaux derives de diamino-2,4 triazine-1,3,5 et leur utilisation pour le traitement et la prevention de la chute des cheveux.
LU87766A1 (fr) * 1990-07-20 1992-03-11 Oreal Utilisation de derives de pyrimidine 3-oxyde pour freiner la chute des cheveux et compositions topiques mises en oeuvre
US5043162A (en) * 1990-09-05 1991-08-27 Trager Seymour F Hair growth promoter
US5143650A (en) * 1990-11-13 1992-09-01 Aster, Inc. Electrophoretic coatable sealant compositions comprising polyvinyl chloride and furnace carbon black
FR2671082B1 (fr) * 1990-12-28 1993-04-16 Oreal Agent a plusieurs composants ou kit de preparation de la forme sulfo-conjuguee de composes pyrimidino- ou triazino-n-oxyde et procede de mise en óoeuvre.
FR2678929A1 (fr) * 1991-07-11 1993-01-15 Oreal Compositions pour freiner la chute des cheveux et pour induire et stimuler leur croissance a base de derives de 2,4-diamino pyrimidine 3-oxyde, nouveaux derives 2,4-diamino pyrimidine 3-oxyde.
US5451407A (en) * 1993-06-21 1995-09-19 Alza Corporation Reduction or prevention of skin irritation or sensitization during transdermal administration of a irritating or sensitizing drug
FR2711060B1 (fr) * 1993-10-13 1995-11-17 Oreal Procédé pour modifier la pousse des poils et/ou des cheveux et compositions utilisables à cet effet.
FR2732597B1 (fr) * 1995-04-05 1997-05-16 Oreal Utilisation dans une composition en tant qu'activateur et/ou stabilisateur de cyclooxygenase d'au moins un derive de pyrimidine substitue en 6
US6159950A (en) * 1998-10-16 2000-12-12 Cornell Research Foundation, Inc. Method of modulating hair growth
FR2785802B1 (fr) 1998-11-12 2002-10-31 Oreal 2-amino, 4-alkylamino pyrimidine 3-oxydes comme anti-inflammatoires
FR2791671B1 (fr) 1999-04-01 2001-05-11 Oreal Nouveaux composes derives d'esters d'acide benzoique, composition les comprenant et utilisation
SE0104421D0 (sv) * 2001-12-21 2001-12-21 Ponsus Pharma Ab New composition
ES2774911T3 (es) 2002-06-21 2020-07-23 Oreal Utilización de la taurina o derivados para el tratamiento de la alopecia
US7326717B2 (en) * 2003-05-06 2008-02-05 L'oreal Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof
US20060193804A1 (en) * 2005-02-24 2006-08-31 L'oreal Haircare use of cyclic amine derivatives
DE102007015282B4 (de) * 2007-03-29 2017-10-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Viskositätsregulator, Verfahren zu dessen Herstellung und dessen Verwendung
FR2920309B1 (fr) 2007-08-28 2010-05-28 Galderma Res & Dev Utilisation de travoprost pour traiter la chute des cheveux
US8551463B2 (en) 2007-10-22 2013-10-08 Living Proof, Inc. Hair care compositions and methods of treating hair
FR2949052B1 (fr) 2009-08-13 2015-03-27 Oreal Procede de traitement cosmetique du cuir chevelu.
FR2953722B1 (fr) 2009-12-16 2012-03-09 Expanscience Lab Composition comprenant au moins un sucre en c7 pour le traitement de l'alopecie, pour le traitement cosmetique des phaneres, et pour le soin des cheveux, cils ou ongles
WO2013158649A1 (en) 2012-04-16 2013-10-24 Case Western Reserve University Compositions and methods of modulating 15-pgdh activity
US9789116B2 (en) 2013-10-15 2017-10-17 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase activity
WO2015085373A1 (en) 2013-12-12 2015-06-18 Cellmid Limited Method of treatment of alopecia with monoterpenoids
CA3254372A1 (en) 2014-12-05 2025-06-28 Case Western Reserve University Compositions and methods of modulating s-nitrosylation
WO2018102552A1 (en) 2016-11-30 2018-06-07 Case Western Reserve University Combinations of 15-pgdh inhibitors with corcosteroids and/or tnf inhibitors and uses thereof
US11718589B2 (en) 2017-02-06 2023-08-08 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase
KR102921276B1 (ko) 2018-11-21 2026-02-03 케이스 웨스턴 리저브 유니버시티 단쇄 데히드로게나아제 활성을 조절하는 조성물 및 방법
FR3106058B1 (fr) * 2020-01-09 2022-01-07 Oreal Procédé de traitement cosmétique
EP3895686B1 (de) 2020-04-14 2025-04-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Natürliche zusammensetzung zur stimulierung des haarwuchses und zur vorbeugung und behandlung von haarausfall
EP3895685A1 (de) 2020-04-14 2021-10-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Natürliche zusammensetzung zur haarwachstumsstimulation und haarverlustverhinderung und behandlung ohne konservierungsmittel
MX2022014637A (es) 2020-05-20 2023-03-03 Rodeo Therapeutics Corp Composiciones y metodos para modular la actividad de deshidrogenasas de cadena corta.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000616A1 (en) * 1984-07-13 1986-01-30 Gail Sansone Bazzano Substituted pyrimidine oxides useful for hair growth promotion

Also Published As

Publication number Publication date
ES2070186T3 (es) 1995-06-01
EP0356271A1 (de) 1990-02-28
JPH0278666A (ja) 1990-03-19
EP0356271B1 (de) 1995-04-05
JP2669903B2 (ja) 1997-10-29
DE68922044T2 (de) 1995-08-03
LU87308A1 (fr) 1990-03-13
US4973474A (en) 1990-11-27
CA1340445C (fr) 1999-03-16
DE68922044D1 (de) 1995-05-11

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