DE68915788T3 - Membranaffinitätsvorrichtung und reinigungsverfahren. - Google Patents
Membranaffinitätsvorrichtung und reinigungsverfahren.Info
- Publication number
- DE68915788T3 DE68915788T3 DE68915788T DE68915788T DE68915788T3 DE 68915788 T3 DE68915788 T3 DE 68915788T3 DE 68915788 T DE68915788 T DE 68915788T DE 68915788 T DE68915788 T DE 68915788T DE 68915788 T3 DE68915788 T3 DE 68915788T3
- Authority
- DE
- Germany
- Prior art keywords
- provides
- membrane affinity
- preselected
- cleaning method
- membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000012528 membrane Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000004140 cleaning Methods 0.000 title 1
- 238000000926 separation method Methods 0.000 abstract 2
- 239000000706 filtrate Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229920002521 macromolecule Polymers 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0081—After-treatment of organic or inorganic membranes
- B01D67/0093—Chemical modification
- B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/04—Hollow fibre modules comprising multiple hollow fibre assemblies
- B01D63/043—Hollow fibre modules comprising multiple hollow fibre assemblies with separate tube sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0002—Organic membrane manufacture
- B01D67/0009—Organic membrane manufacture by phase separation, sol-gel transition, evaporation or solvent quenching
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0081—After-treatment of organic or inorganic membranes
- B01D67/0093—Chemical modification
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/08—Hollow fibre membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/08—Hollow fibre membranes
- B01D69/085—Details relating to the spinneret
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/14—Dynamic membranes
- B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/644—Coagulation factor IXa (3.4.21.22)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21022—Coagulation factor IXa (3.4.21.22)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/24—Specific pressurizing or depressurizing means
- B01D2313/243—Pumps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2323/00—Details relating to membrane preparation
- B01D2323/38—Graft polymerization
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/36—Hydrophilic membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/38—Hydrophobic membranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
- G01N2030/524—Physical parameters structural properties
- G01N2030/527—Physical parameters structural properties sorbent material in form of a membrane
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
- G01N2030/524—Physical parameters structural properties
- G01N2030/528—Monolithic sorbent material
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Manufacturing & Machinery (AREA)
- Dispersion Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Water Supply & Treatment (AREA)
- Transplantation (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26506188A | 1988-10-31 | 1988-10-31 | |
US42826389A | 1989-10-26 | 1989-10-26 | |
PCT/US1989/004847 WO1990005018A1 (en) | 1988-10-31 | 1989-10-30 | Membrane affinity apparatus and purification methods related thereto |
Publications (3)
Publication Number | Publication Date |
---|---|
DE68915788D1 DE68915788D1 (de) | 1994-07-07 |
DE68915788T2 DE68915788T2 (de) | 1994-10-20 |
DE68915788T3 true DE68915788T3 (de) | 1998-02-12 |
Family
ID=26950944
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68915788T Expired - Fee Related DE68915788T3 (de) | 1988-10-31 | 1989-10-30 | Membranaffinitätsvorrichtung und reinigungsverfahren. |
DE89912702T Pending DE483143T1 (de) | 1988-10-31 | 1989-10-30 | Membranaffinitätsvorrichtung und reinigungsverfahren. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE89912702T Pending DE483143T1 (de) | 1988-10-31 | 1989-10-30 | Membranaffinitätsvorrichtung und reinigungsverfahren. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0483143B2 (de) |
AT (1) | ATE106272T1 (de) |
AU (1) | AU4524789A (de) |
CA (1) | CA2001720C (de) |
DE (2) | DE68915788T3 (de) |
WO (1) | WO1990005018A1 (de) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1844917A2 (de) | 2006-03-24 | 2007-10-17 | Entex Rust & Mitschke GmbH | Verfahren zur Verarbeitung von zu entgasenden Produkten |
DE102007059299A1 (de) | 2007-05-16 | 2008-11-20 | Entex Rust & Mitschke Gmbh | Vorrichtung zur Verarbeitung von zu entgasenden Produkten |
DE102011112081A1 (de) | 2011-05-11 | 2015-08-20 | Entex Rust & Mitschke Gmbh | Verfahren zur Verarbeitung von Elasten |
DE102015001167A1 (de) | 2015-02-02 | 2016-08-04 | Entex Rust & Mitschke Gmbh | Entgasen bei der Extrusion von Kunststoffen |
WO2017001048A1 (de) | 2015-07-02 | 2017-01-05 | Entex Rust & Mitschke Gmbh | Verfahren zur verarbeitung von produkten im extruder |
DE102016002143A1 (de) | 2016-02-25 | 2017-08-31 | Entex Rust & Mitschke Gmbh | Füllteilmodul in Planetwalzenextruderbauweise |
DE102017001093A1 (de) | 2016-04-07 | 2017-10-26 | Entex Rust & Mitschke Gmbh | Entgasen bei der Extrusion von Kunststoffen mit Filterscheiben aus Sintermetall |
DE102017006638A1 (de) | 2017-07-13 | 2019-01-17 | Entex Rust & Mitschke Gmbh | Füllteilmodul in Planetwalzenextruderbauweise |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5683916A (en) * | 1988-10-31 | 1997-11-04 | Hemasure Inc. | Membrane affinity apparatus and purification methods related thereto |
US5344701A (en) * | 1992-06-09 | 1994-09-06 | Minnesota Mining And Manufacturing Company | Porous supports having azlactone-functional surfaces |
US5292514A (en) * | 1992-06-24 | 1994-03-08 | Minnesota Mining And Manufacturing Company | Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof |
US5531893A (en) * | 1993-02-12 | 1996-07-02 | Gelman Sciences Inc. | Inter-penetrating network charge modified microporous membrane |
FR2705251B1 (fr) * | 1993-05-13 | 1995-07-07 | France Etat Armement | Détermination de substances dans un milieu liquide par filtration tangentielle. |
DE4337573C1 (de) * | 1993-11-04 | 1995-05-18 | Octapharma Ag | Verfahren zur Herstellung einer virusinaktivierten Faktor VIII enthaltenden Fraktion mittels chromatographischer Methoden |
US5456835A (en) * | 1993-11-08 | 1995-10-10 | Hemasure, Inc. | Device and process for removing free hemoglobin from blood |
DE4342132C1 (de) | 1993-12-10 | 1994-11-03 | Octapharma Ag | Verfahren zur Herstellung virusinaktivierte Vitamin K abhängige Plasmakomponenten sowie Protein C und Protein S enthaltender Mittel durch Membran-Chromatographie |
JPH09508823A (ja) * | 1994-01-10 | 1997-09-09 | ヒマシュア,インコーポレイテッド | 血液からの白血球及びウイルス不活性化作用物質の除去装置とプロセス |
US5639376A (en) * | 1994-01-10 | 1997-06-17 | Hemasure, Inc. | Process for simultaneously removing leukocytes and methylene blue from plasma |
WO1995021177A1 (de) | 1994-02-07 | 1995-08-10 | Qiagen Gmbh | Verfahren zur herstellung endotoxinfreier oder an endotoxin abgereicherter nucleinsäuren und/oder oligonucleotide für die gentherapie |
US5990301A (en) * | 1994-02-07 | 1999-11-23 | Qiagen Gmbh | Process for the separation and purification of nucleic acids from biological sources |
US5476665A (en) * | 1994-04-13 | 1995-12-19 | Minnesota Mining And Manufacturing Company | Azlactone functional particles incorporated in a membrane formed by solvent phase inversion |
DE4432627B4 (de) * | 1994-09-14 | 2008-09-25 | Sartorius Stedim Biotech Gmbh | Filtrationseinheit zur Abtrennung von Stoffen mit Membranadsorbern |
ATE235952T1 (de) | 1996-02-01 | 2003-04-15 | Mat Adsorption Technologies Gm | Vorrichtung und verfahren zur stoffspezifischen behandlung von fluiden |
US5868936A (en) * | 1996-06-20 | 1999-02-09 | Baxter International Inc. | Affinity membrane system and method of using same |
ES2172018T3 (es) | 1996-11-06 | 2002-09-16 | Mat Adsorption Technologies Gm | Modulo de membrana para el tratamiento de fluidos especifico de la sustancia. |
DE59707888D1 (de) | 1996-12-21 | 2002-09-05 | Mat Adsorption Technologies Gm | Membranmodul mit schichtförmig angeordneten hohlfasermembranen |
IL130129A0 (en) * | 1996-12-31 | 2000-06-01 | Althin Medical Inc | Polysulfone semipermeable membranes and methods for making the same |
WO1998057733A1 (de) | 1997-06-14 | 1998-12-23 | Akzo Nobel N.V. | Membranmodul mit einseitig eingebetteten hohlfasermembranen |
US7144505B2 (en) | 1997-09-18 | 2006-12-05 | Baxter International Inc. | Melt-spun polysulfone semipermeable membranes and methods for making the same |
US6218441B1 (en) | 1997-09-18 | 2001-04-17 | Timothy B. Meluch | Melt-spun polysulfone semipermeable membranes and methods for making the same |
US6096726A (en) * | 1998-03-11 | 2000-08-01 | Surface Solutions Laboratories Incorporated | Multicomponent complex for use with substrate |
AU2830400A (en) * | 1999-03-05 | 2000-09-28 | Mitsubishi Rayon Company Limited | Carriers having biological substance |
US6861001B2 (en) * | 1999-12-02 | 2005-03-01 | The General Hospital Corporation | Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon |
WO2001066237A1 (de) | 2000-03-07 | 2001-09-13 | Mat Adsorption Technologies Gmbh & Co. Kg | Modul mit membranelementen in cross-flow und in dead-end anordnung |
GB0515577D0 (en) | 2005-07-29 | 2005-09-07 | Amersham Biosciences Ab | Process for cross-linking cellulose ester membranes |
FR2910877B1 (fr) | 2006-12-28 | 2009-09-25 | Eurocopter France | Amelioration aux rotors de giravions equipes d'amortisseurs interpales |
DE102008003090A1 (de) * | 2008-01-03 | 2009-07-16 | Fresenius Medical Care Deutschland Gmbh | Hohlfasermembran |
US10391423B2 (en) | 2010-01-25 | 2019-08-27 | Spf Technologies Llc | Stackable planar adsorptive devices |
US11219844B2 (en) | 2010-01-25 | 2022-01-11 | Spf Technologies Llc | Stackable planar adsorptive devices |
US10507409B2 (en) | 2016-03-12 | 2019-12-17 | Spf Technologies, Llc | Hyper-productive chromatography system and process |
US11395980B2 (en) | 2010-01-25 | 2022-07-26 | Spf Technologies Llc | Chromatographic cassette |
CN104736317B (zh) | 2012-10-11 | 2017-09-22 | 恩特克斯拉斯特及米施克有限责任公司 | 用于加工易粘接的塑料的挤压机 |
DE102012221378A1 (de) * | 2012-11-22 | 2014-05-22 | Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH | Verfahren zur Herstellung einer integral-asymmetrischen Hohlfaden-Polymermembran, integral-asymmetrische Hohlfaden-Polymermembran, Filtrationsmodul und Verwendung |
CN107261556B (zh) * | 2013-08-12 | 2019-08-16 | Spf技术有限责任公司 | 可堆叠的平面吸附装置 |
CN106422780B (zh) * | 2016-11-02 | 2022-08-30 | 中国石油大学(华东) | 一种可连续操作的循环式正渗透高盐有机废水处理系统 |
DE102017216030A1 (de) | 2017-09-12 | 2019-03-14 | Fresenius Medical Care Deutschland Gmbh | Verfahren zum verarbeiten einer proteinhaltigen suspension oder proteinhaltigen lösung |
CN113522044B (zh) * | 2021-08-16 | 2022-03-29 | 南京工业大学 | 一种血浆分离膜的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3993560A (en) * | 1975-02-27 | 1976-11-23 | Halpern Richard M | Method and apparatus for monitoring cellular activities |
SE8006102L (sv) * | 1980-09-02 | 1982-03-03 | Gambro Ab | Sett att utvinna en peptidinnehallande forening samt medel for genomforande av settet |
US4693985A (en) * | 1984-08-21 | 1987-09-15 | Pall Corporation | Methods of concentrating ligands and active membranes used therefor |
JPH0611328B2 (ja) * | 1984-10-11 | 1994-02-16 | 株式会社クラレ | 生理活性物質を固定した多孔性中空繊維を使用した液の処理方法 |
JPS62298536A (ja) * | 1986-06-17 | 1987-12-25 | Green Cross Corp:The | 生理活性物質の自動精製方法および自動精製装置 |
JPH02503388A (ja) * | 1987-03-10 | 1990-10-18 | マサチユセツツ・インスチチユート・オブ・テクノロジー | ヘパリンの中和 |
-
1989
- 1989-10-27 CA CA002001720A patent/CA2001720C/en not_active Expired - Fee Related
- 1989-10-30 AT AT89912702T patent/ATE106272T1/de not_active IP Right Cessation
- 1989-10-30 AU AU45247/89A patent/AU4524789A/en not_active Abandoned
- 1989-10-30 DE DE68915788T patent/DE68915788T3/de not_active Expired - Fee Related
- 1989-10-30 EP EP89912702A patent/EP0483143B2/de not_active Expired - Lifetime
- 1989-10-30 DE DE89912702T patent/DE483143T1/de active Pending
- 1989-10-30 WO PCT/US1989/004847 patent/WO1990005018A1/en active IP Right Grant
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1844917A2 (de) | 2006-03-24 | 2007-10-17 | Entex Rust & Mitschke GmbH | Verfahren zur Verarbeitung von zu entgasenden Produkten |
DE102007059299A1 (de) | 2007-05-16 | 2008-11-20 | Entex Rust & Mitschke Gmbh | Vorrichtung zur Verarbeitung von zu entgasenden Produkten |
EP1997608A2 (de) | 2007-05-16 | 2008-12-03 | Entex Rust & Mitschke GmbH | Verfahren zur Verarbeitung von zu entgasenden Produkten |
DE102011112081A1 (de) | 2011-05-11 | 2015-08-20 | Entex Rust & Mitschke Gmbh | Verfahren zur Verarbeitung von Elasten |
DE102015001167A1 (de) | 2015-02-02 | 2016-08-04 | Entex Rust & Mitschke Gmbh | Entgasen bei der Extrusion von Kunststoffen |
WO2017001048A1 (de) | 2015-07-02 | 2017-01-05 | Entex Rust & Mitschke Gmbh | Verfahren zur verarbeitung von produkten im extruder |
DE102015008406A1 (de) | 2015-07-02 | 2017-04-13 | Entex Rust & Mitschke Gmbh | Verfahren zur Bearbeitung von Produkten im Extruder |
DE102016002143A1 (de) | 2016-02-25 | 2017-08-31 | Entex Rust & Mitschke Gmbh | Füllteilmodul in Planetwalzenextruderbauweise |
DE102017001093A1 (de) | 2016-04-07 | 2017-10-26 | Entex Rust & Mitschke Gmbh | Entgasen bei der Extrusion von Kunststoffen mit Filterscheiben aus Sintermetall |
DE102017006638A1 (de) | 2017-07-13 | 2019-01-17 | Entex Rust & Mitschke Gmbh | Füllteilmodul in Planetwalzenextruderbauweise |
WO2019011461A1 (de) | 2017-07-13 | 2019-01-17 | Entex Rust & Mitschke Gmbh | Füllteilmodul in planetwalzenextruderbauweise |
Also Published As
Publication number | Publication date |
---|---|
EP0483143A4 (de) | 1991-07-24 |
EP0483143B2 (de) | 1997-04-09 |
CA2001720A1 (en) | 1990-04-30 |
DE68915788T2 (de) | 1994-10-20 |
DE483143T1 (de) | 1994-03-17 |
WO1990005018A1 (en) | 1990-05-17 |
EP0483143B1 (de) | 1994-06-01 |
DE68915788D1 (de) | 1994-07-07 |
ATE106272T1 (de) | 1994-06-15 |
EP0483143A1 (de) | 1992-05-06 |
AU4524789A (en) | 1990-05-28 |
CA2001720C (en) | 2001-10-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE68915788D1 (de) | Membranaffinitätsvorrichtung und reinigungsverfahren. | |
US3966609A (en) | Chromatographic device | |
FR2374940A1 (fr) | Procede et appareil pour augmenter la proportion d'un gaz determine dans un melange gazeux | |
ATE9875T1 (de) | Verfahren und vorrichtung zur abscheidung gasfoermiger komponenten durch selektive adsorption. | |
EP0196790A3 (de) | Verfahren und Apparat zum Extrahieren von DNS aus Proben | |
TW351678B (en) | Method for fractionating a solution to fractionate a solution | |
DE69612973D1 (de) | Verbesserung an der behandlung von proben | |
DE3850287D1 (de) | Vorrichtung und Verfahren zur Trennung von Blutphasen. | |
DE69111917T2 (de) | Druckwechsel-Adsorptionsverfahren zur Trennung von Gasgemischen. | |
ATE21035T1 (de) | Vorrichtung zur sterilitaetspruefung von fluiden. | |
AU6252290A (en) | Blood testing device | |
FR2459479B1 (fr) | Procede de separation d'une substance proteinique a partir d'une solution la contenant par filtration d'affinite et application dudit procede aux dosages enzymatiques | |
ATE111762T1 (de) | Verfahren und vorrichtung zum entwässern von schlämmen und ähnlichen substanzen. | |
CA1199878A (en) | Method and apparatus for plasmapheresis | |
SE7312462L (sv) | Dialysanordning for rening av ett medium, foretredesvis blod | |
JPS57168157A (en) | High performance liquid chromatography column and analysis method using the same | |
FR2639050B1 (fr) | Procede de stabilisation des conditions de pression et de debit dans un appareil de classage, et appareil de classage le mettant en oeuvre | |
WO1999044718A8 (en) | System and method of filtering and collecting blood or blood products | |
GB1277025A (en) | Improvements in or relating to apparatus for applying powder to an elongate article | |
GB2223756A (en) | Protein purification process | |
ES463195A1 (es) | Una tobera de ventilacion perfeccionada. | |
DE3874750D1 (de) | Verfahren und vorrichtung zum konzentrieren makromolekularer loesungen. | |
Bier | [3] Preparative electrophoresis | |
Leaver et al. | A method development study of the production of albumin from animal blood by ion-exchange chromatography | |
EP0388468A4 (en) | Hydrophilic polypropylene porous membrane, process for its production, and apparatus for separating blood plasma |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8366 | Restricted maintained after opposition proceedings | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: HEMASURE,INC., MARLBOROUGH, MASS., US |
|
8339 | Ceased/non-payment of the annual fee |