DE68914087D1 - Spezifische Liganden für Östrogen- und Progestagen-Steroidhomonrezeptoren, deren Verwendung und Synthesezwischenprodukte. - Google Patents

Spezifische Liganden für Östrogen- und Progestagen-Steroidhomonrezeptoren, deren Verwendung und Synthesezwischenprodukte.

Info

Publication number
DE68914087D1
DE68914087D1 DE89402862T DE68914087T DE68914087D1 DE 68914087 D1 DE68914087 D1 DE 68914087D1 DE 89402862 T DE89402862 T DE 89402862T DE 68914087 T DE68914087 T DE 68914087T DE 68914087 D1 DE68914087 D1 DE 68914087D1
Authority
DE
Germany
Prior art keywords
hormone receptors
progestagen
estrogen
ligands
steroid hormone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE89402862T
Other languages
English (en)
Other versions
DE68914087T2 (de
Inventor
Marc Zeicher
Jacques Quivy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
La Region Wallonne
Original Assignee
La Region Wallonne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by La Region Wallonne filed Critical La Region Wallonne
Application granted granted Critical
Publication of DE68914087D1 publication Critical patent/DE68914087D1/de
Publication of DE68914087T2 publication Critical patent/DE68914087T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE68914087T 1988-10-19 1989-10-17 Spezifische Liganden für Östrogen- und Progestagen-Steroidhomonrezeptoren, deren Verwendung und Synthesezwischenprodukte. Expired - Lifetime DE68914087T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8813737A FR2637803B1 (fr) 1988-10-19 1988-10-19 Ligands specifiques de recepteurs d'hormones steroides estrogenes et progestagenes, application et produits intermediaires de synthese

Publications (2)

Publication Number Publication Date
DE68914087D1 true DE68914087D1 (de) 1994-04-28
DE68914087T2 DE68914087T2 (de) 1994-09-08

Family

ID=9371153

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68914087T Expired - Lifetime DE68914087T2 (de) 1988-10-19 1989-10-17 Spezifische Liganden für Östrogen- und Progestagen-Steroidhomonrezeptoren, deren Verwendung und Synthesezwischenprodukte.

Country Status (7)

Country Link
US (1) US5002753A (de)
EP (1) EP0365421B1 (de)
JP (1) JP2779011B2 (de)
AT (1) ATE103291T1 (de)
CA (1) CA2000979C (de)
DE (1) DE68914087T2 (de)
FR (1) FR2637803B1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2613937B1 (fr) * 1987-04-17 1989-07-21 Ire Celltarg Sa Ligands specifiques de recepteurs d'hormones steroides utiles pour la therapie ciblee ou l'imagerie medicale notamment du cancer
CN1041829C (zh) * 1993-06-28 1999-01-27 中国人民军事医学科学院放射医学研究所 17α-乙炔雌三醇-3-环戊醚的制备方法
US5427766A (en) * 1993-11-15 1995-06-27 The Dow Chemical Company Radiolabeled steroids for use in radiochemical-guided surgery
US5922699A (en) 1996-06-07 1999-07-13 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
WO2008154644A1 (en) * 2007-06-12 2008-12-18 Case Western Reserve University Targeted cell death

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7405626A (nl) * 1974-04-26 1975-10-28 Akzo Nv Nieuwe 11-gesubstitueerde steroiden van de oestraanreeks.
JPS6051808A (ja) * 1983-08-31 1985-03-23 Sumitomo Electric Ind Ltd 光フアイバユニツト入り架空地線の接続部
DE3337179A1 (de) * 1983-10-10 1985-05-23 Schering AG, 1000 Berlin und 4709 Bergkamen Estran- und androstan-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende praeparate
DE3565157D1 (en) * 1984-07-20 1988-10-27 Tol O Matic Inc Rotary actuator
DE3427795A1 (de) * 1984-07-25 1986-02-06 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 17(alpha)-halogenvinyl-estran-derivate, ihre herstellung und verwendung in der medizin
FR2613937B1 (fr) * 1987-04-17 1989-07-21 Ire Celltarg Sa Ligands specifiques de recepteurs d'hormones steroides utiles pour la therapie ciblee ou l'imagerie medicale notamment du cancer

Also Published As

Publication number Publication date
US5002753A (en) 1991-03-26
EP0365421B1 (de) 1994-03-23
JP2779011B2 (ja) 1998-07-23
EP0365421A1 (de) 1990-04-25
DE68914087T2 (de) 1994-09-08
JPH02174794A (ja) 1990-07-06
CA2000979A1 (fr) 1990-04-19
FR2637803B1 (fr) 1993-07-09
FR2637803A1 (fr) 1990-04-20
CA2000979C (fr) 2000-06-13
ATE103291T1 (de) 1994-04-15

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