DE68913962T2 - Bioreaktor und vorrichtung zur kultivierung von tierischen zellen. - Google Patents

Bioreaktor und vorrichtung zur kultivierung von tierischen zellen.

Info

Publication number
DE68913962T2
DE68913962T2 DE68913962T DE68913962T DE68913962T2 DE 68913962 T2 DE68913962 T2 DE 68913962T2 DE 68913962 T DE68913962 T DE 68913962T DE 68913962 T DE68913962 T DE 68913962T DE 68913962 T2 DE68913962 T2 DE 68913962T2
Authority
DE
Germany
Prior art keywords
bioreactor
animal cells
cultivating animal
cultivating
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68913962T
Other languages
English (en)
Other versions
DE68913962D1 (de
Inventor
Bernard Besnainou
Alain Philippe
Pierre Lessart
Marie-Paule Elluard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Application granted granted Critical
Publication of DE68913962D1 publication Critical patent/DE68913962D1/de
Publication of DE68913962T2 publication Critical patent/DE68913962T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/10—Rotating vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/12—Pulsatile flow
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02—Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M39/00—Means for cleaning the apparatus or avoiding unwanted deposits of microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/813—Continuous fermentation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE68913962T 1988-12-20 1989-12-19 Bioreaktor und vorrichtung zur kultivierung von tierischen zellen. Expired - Fee Related DE68913962T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8816851A FR2640638B1 (fr) 1988-12-20 1988-12-20 Bioreacteur et dispositif pour la culture de cellules animales
PCT/FR1989/000664 WO1990006990A1 (fr) 1988-12-20 1989-12-19 Bioreacteur et dispositif pour la culture de cellules animales

Publications (2)

Publication Number Publication Date
DE68913962D1 DE68913962D1 (de) 1994-04-21
DE68913962T2 true DE68913962T2 (de) 1994-09-15

Family

ID=9373198

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68913962T Expired - Fee Related DE68913962T2 (de) 1988-12-20 1989-12-19 Bioreaktor und vorrichtung zur kultivierung von tierischen zellen.

Country Status (7)

Country Link
US (1) US5064764A (de)
EP (1) EP0403629B1 (de)
JP (1) JPH03502891A (de)
DE (1) DE68913962T2 (de)
FI (1) FI903987A0 (de)
FR (1) FR2640638B1 (de)
WO (1) WO1990006990A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10120835A1 (de) * 2001-04-27 2002-11-07 Sifin Inst Fuer Immunpraeparat Verfahren zur Herstellung von monoklonalen Antikörpern
DE102007020671A1 (de) 2007-05-01 2008-11-06 Justus-Liebig-Universität Giessen Verfahren und Vorrichtung zum kontaktfreien Materialwachstum in einer strömenden Lösung (FLow suspended solution growth (FSSG))

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FR2679248A1 (fr) * 1991-07-19 1993-01-22 Commissariat Energie Atomique Bioreacteur et dispositif pour la culture de cellules animales.
GB9119955D0 (en) * 1991-09-18 1991-10-30 Imperial College Treatment of aqueous supplies containing organic material
US5527467A (en) * 1992-01-10 1996-06-18 Baxter International Inc. Rectifying dialyzer, bioreactor and membrane
US5240614A (en) * 1992-01-10 1993-08-31 Baxter International Inc. Process for removing unwanted materials from fluids and for producing biological products
US5480552A (en) * 1992-01-10 1996-01-02 Baxter International Inc. Method for concentrating a solute with an oscillating filtration device
KR100304224B1 (ko) * 1993-03-09 2001-11-22 데이비드 씨. 맥키, 토마스 제어. 시바티노 정류투석기,생체반응기및막
FR2706483B1 (fr) * 1993-06-09 1995-09-01 Bertin & Cie Bioréacteur, destiné notamment à la culture de cellules.
US5712154A (en) * 1995-06-07 1998-01-27 W.R. Grace & Co.-Conn. Dual fiber bioreactor
US20020182730A1 (en) * 1995-07-26 2002-12-05 Micheal L. Gruenberg Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease
US5955353A (en) * 1997-05-22 1999-09-21 Excorp Medical, Inc. Hollow fiber bioreactor with an extrafilament flow plug
US6235196B1 (en) 1998-04-23 2001-05-22 Alliedsignal Inc. Biological wastewater treatment system
US6673008B1 (en) 1998-04-28 2004-01-06 Ronald J. Thompson Fallopian tube and method of in vitro fertilization and embryo development
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FR2821947B1 (fr) * 2001-03-12 2003-05-16 Canon Kk Procede et dispositif de validation de parametres definissant une image
US6696287B2 (en) * 2001-03-29 2004-02-24 The Brigham And Women's Hospital, Inc. System for co-culturing bacteria and eukaryotic cells
US6582955B2 (en) * 2001-05-11 2003-06-24 Spectrum Laboratories, Inc. Bioreactor with application as blood therapy device
KR20020088848A (ko) 2001-05-21 2002-11-29 (주)코아바이오텍 세포배양관 및 이를 이용한 대량 세포배양기
US20030134341A1 (en) * 2001-09-19 2003-07-17 Medcell Biologics, Llc. Th1 cell adoptive immunotherapy
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US20030175272A1 (en) * 2002-03-07 2003-09-18 Medcell Biologics, Inc. Re-activated T-cells for adoptive immunotherapy
DE10251668A1 (de) * 2002-11-06 2004-05-27 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Tieftemperaturspeicherung von Suspensionsproben in hängenden Probenkammern
US7531351B2 (en) * 2004-06-14 2009-05-12 Probiogen Ag Liquid-gas-phase exposure reactor for cell culturing
US8778669B2 (en) 2009-07-22 2014-07-15 Corning Incorporated Multilayer tissue culture vessel
DE102010048422B4 (de) * 2010-10-15 2016-01-07 Thomas Melin Verfahren zur Produktisolierung und Substratzufuhr in einem Bioreaktor
US9005550B2 (en) 2012-10-29 2015-04-14 Corning Incorporated Multi-layered cell culture vessel with manifold grips
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10120835A1 (de) * 2001-04-27 2002-11-07 Sifin Inst Fuer Immunpraeparat Verfahren zur Herstellung von monoklonalen Antikörpern
DE10120835C2 (de) * 2001-04-27 2003-04-10 Sifin Inst Fuer Immunpraeparat Verfahren zur Herstellung von monoklonalen Antikörpern
DE102007020671A1 (de) 2007-05-01 2008-11-06 Justus-Liebig-Universität Giessen Verfahren und Vorrichtung zum kontaktfreien Materialwachstum in einer strömenden Lösung (FLow suspended solution growth (FSSG))

Also Published As

Publication number Publication date
EP0403629B1 (de) 1994-03-16
US5064764A (en) 1991-11-12
EP0403629A1 (de) 1990-12-27
FR2640638A1 (fr) 1990-06-22
JPH03502891A (ja) 1991-07-04
WO1990006990A1 (fr) 1990-06-28
FR2640638B1 (fr) 1991-02-15
FI903987A0 (fi) 1990-08-13
DE68913962D1 (de) 1994-04-21

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