DE68909961T2 - 2-Aminoacetamid Derivate. - Google Patents
2-Aminoacetamid Derivate.Info
- Publication number
- DE68909961T2 DE68909961T2 DE89300164T DE68909961T DE68909961T2 DE 68909961 T2 DE68909961 T2 DE 68909961T2 DE 89300164 T DE89300164 T DE 89300164T DE 68909961 T DE68909961 T DE 68909961T DE 68909961 T2 DE68909961 T2 DE 68909961T2
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- pharmaceutically acceptable
- sedatives
- epilepsy
- diluent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14586588A | 1988-01-20 | 1988-01-20 | |
US14594388A | 1988-01-20 | 1988-01-20 | |
US07/145,866 US4871872A (en) | 1988-01-20 | 1988-01-20 | 2-[(2-aminoacetyl)amino]acetamide derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68909961D1 DE68909961D1 (de) | 1993-11-25 |
DE68909961T2 true DE68909961T2 (de) | 1994-02-10 |
Family
ID=27386328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE89300164T Expired - Fee Related DE68909961T2 (de) | 1988-01-20 | 1989-01-10 | 2-Aminoacetamid Derivate. |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP0326240B1 (de) |
JP (1) | JPH02503089A (de) |
AT (1) | ATE96144T1 (de) |
CA (1) | CA1315477C (de) |
DE (1) | DE68909961T2 (de) |
DK (1) | DK460789A (de) |
IE (1) | IE890161L (de) |
PT (1) | PT89483B (de) |
WO (1) | WO1989006646A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG52662A1 (en) * | 1988-08-12 | 1998-09-28 | Astra Ab | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2449638A (en) * | 1946-05-10 | 1948-09-21 | Wyeth Corp | Substituted glycinamides |
DE955508C (de) * | 1954-07-28 | 1957-01-03 | Cilag Ag | Verfahren zur Herstellung von antikonvulsivisch wirkenden Carbonsaeureamiden |
GB1420067A (en) * | 1972-02-15 | 1976-01-07 | Astra Laekemedel Ab | Aryldiamides |
SE408171B (sv) * | 1975-09-04 | 1979-05-21 | Astra Laekemedel Ab | Analogiforfarande for framstellning av nya aralkylamider av 2-aminopropropionsyra, vilka amider har framakologiska egenskaper |
-
1989
- 1989-01-10 DE DE89300164T patent/DE68909961T2/de not_active Expired - Fee Related
- 1989-01-10 WO PCT/US1989/000041 patent/WO1989006646A1/en not_active Application Discontinuation
- 1989-01-10 EP EP89300164A patent/EP0326240B1/de not_active Expired - Lifetime
- 1989-01-10 AT AT89300164T patent/ATE96144T1/de not_active IP Right Cessation
- 1989-01-10 EP EP89902415A patent/EP0401253A1/de active Pending
- 1989-01-10 JP JP1502245A patent/JPH02503089A/ja active Pending
- 1989-01-19 IE IE890161A patent/IE890161L/xx unknown
- 1989-01-19 PT PT89483A patent/PT89483B/pt active IP Right Grant
- 1989-01-20 CA CA000588803A patent/CA1315477C/en not_active Expired - Fee Related
- 1989-09-19 DK DK460789A patent/DK460789A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE68909961D1 (de) | 1993-11-25 |
EP0401253A1 (de) | 1990-12-12 |
EP0326240A1 (de) | 1989-08-02 |
EP0326240B1 (de) | 1993-10-20 |
DK460789D0 (da) | 1989-09-19 |
CA1315477C (en) | 1993-03-30 |
WO1989006646A1 (en) | 1989-07-27 |
PT89483A (pt) | 1989-10-04 |
JPH02503089A (ja) | 1990-09-27 |
PT89483B (pt) | 1994-02-28 |
ATE96144T1 (de) | 1993-11-15 |
IE890161L (en) | 1989-07-20 |
DK460789A (da) | 1989-11-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |