EP0731110A1
(de)
*
|
1987-12-10 |
1996-09-11 |
La Jolla Cancer Research Foundation |
Verfahren zur Herstellung von konformationell stabilisierten Zelladhäsionspeptiden
|
US5827821A
(en)
*
|
1987-12-10 |
1998-10-27 |
The Burnham Institute |
Conformationally stabilized cell adhesion peptides
|
US5053393A
(en)
*
|
1988-07-20 |
1991-10-01 |
Monsanto Company |
Novel platelet-aggregation inhibitor
|
US5037808A
(en)
*
|
1988-07-20 |
1991-08-06 |
Monsanto Co. |
Indolyl platelet-aggregation inhibitors
|
US5807828A
(en)
*
|
1989-06-16 |
1998-09-15 |
Cor Therapeutics, Inc. |
Platelet aggregation inhibitors
|
US5686567A
(en)
*
|
1989-06-16 |
1997-11-11 |
Cor Therapeutics, Inc. |
Platelet aggregation inhibitors
|
US5384309A
(en)
*
|
1989-07-17 |
1995-01-24 |
Genentech, Inc. |
Cyclized peptides and their use as platelet aggregation inhibitors
|
US5332726A
(en)
*
|
1989-09-29 |
1994-07-26 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Antithrombotic peptides and pseudopeptides
|
US5780303A
(en)
*
|
1990-04-06 |
1998-07-14 |
La Jolla Cancer Research Foundation |
Method and composition for treating thrombosis
|
US5672585A
(en)
*
|
1990-04-06 |
1997-09-30 |
La Jolla Cancer Research Foundation |
Method and composition for treating thrombosis
|
DK0527798T3
(da)
*
|
1990-04-06 |
1997-12-15 |
Jolla Cancer Res Found |
Fremgangsmåde og sammensætning til behandling af thrombose
|
US5648330A
(en)
*
|
1990-04-06 |
1997-07-15 |
La Jolla Cancer Research Foundation |
Method and composition for treating vascular graft occlusion
|
US6521594B1
(en)
|
1990-04-06 |
2003-02-18 |
La Jolla Cancer Research Foundation |
Method and composition for treating thrombosis
|
US5612311A
(en)
|
1990-04-06 |
1997-03-18 |
La Jolla Cancer Research Foundation |
Method and composition for treating thrombosis
|
TW201303B
(de)
*
|
1990-07-05 |
1993-03-01 |
Hoffmann La Roche |
|
US5260277A
(en)
*
|
1990-09-10 |
1993-11-09 |
Tanabe Seiyaku Co., Ltd. |
Guanidinyl and related cell adhesion modulation compounds
|
US5264420A
(en)
*
|
1990-09-27 |
1993-11-23 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
KR100210206B1
(ko)
*
|
1991-03-06 |
1999-07-15 |
윌리암스 로저 에이 |
혈소판 응집 억제제로서 유용한 페닐아미딘 유도체
|
MX9201416A
(es)
*
|
1991-03-28 |
1992-10-01 |
Rhone Poulenc Rorer Int |
Peptidos y pseudopeptidos antitromboticos.
|
CA2106314A1
(en)
*
|
1991-04-05 |
1992-10-06 |
John P. Burnier |
Platelet aggregation inhibitors having high specification for gpiibiiia
|
WO1992018117A1
(en)
*
|
1991-04-11 |
1992-10-29 |
Rhone-Poulenc Rorer International (Holdings), Inc. |
Anti-thrombotic peptide and pseudopeptide derivatives
|
WO1992019595A1
(en)
*
|
1991-05-07 |
1992-11-12 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
US5220050A
(en)
*
|
1991-05-17 |
1993-06-15 |
G. D. Searle & Co. |
Peptide mimetic compounds useful as platelet aggregation inhibitors
|
US5239113A
(en)
*
|
1991-10-15 |
1993-08-24 |
Monsanto Company |
Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof
|
CA2115848A1
(en)
*
|
1991-10-15 |
1993-04-16 |
Philippe Roger Bovy |
Substituted heterocyclic derivatives useful as platelet aggregation inhibitors
|
US5254573A
(en)
*
|
1991-10-15 |
1993-10-19 |
Monsanto Company |
Substituted heterocyclic derivatives useful as platelet aggregation inhibitors
|
US5625093A
(en)
*
|
1991-10-15 |
1997-04-29 |
G. D. Searle & Co. |
Substituted β-amino acid derivatives useful as platelet aggregation inhibitors
|
US5272158A
(en)
*
|
1991-10-29 |
1993-12-21 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
US5389631A
(en)
*
|
1991-10-29 |
1995-02-14 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
WO1993008823A1
(en)
*
|
1991-11-06 |
1993-05-13 |
Tanabe Seiyaku Co., Ltd. |
Guanidinyl and related cell adhesion modulation compounds
|
CA2117282A1
(en)
*
|
1991-11-22 |
1993-05-27 |
Ofer Lider |
Non-peptidic surrogates of the arg-gly-asp sequence and pharmaceutical compositions comprosing them
|
AU3241693A
(en)
*
|
1991-12-13 |
1993-07-19 |
G.D. Searle & Co. |
Phenyl amidines lactones useful as platelet aggregation inhibitors
|
US5258398A
(en)
*
|
1991-12-16 |
1993-11-02 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Antithrombotic diaminoalkanoic acid derivatives
|
US5424334A
(en)
*
|
1991-12-19 |
1995-06-13 |
G. D. Searle & Co. |
Peptide mimetic compounds useful as platelet aggregation inhibitors
|
US5264457A
(en)
*
|
1992-02-14 |
1993-11-23 |
G. D. Searle & Co. |
Phenyl amidines sulfonamides useful as platelet aggregation inhibitors
|
US5227490A
(en)
*
|
1992-02-21 |
1993-07-13 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
TW223629B
(de)
*
|
1992-03-06 |
1994-05-11 |
Hoffmann La Roche |
|
HUT63609A
(en)
*
|
1992-03-10 |
1993-09-28 |
Sandoz Ag |
Process for producing new derivatives and isosters of beta-amino acids and pharmaceutical compositions comprising such compounds
|
DE4212304A1
(de)
*
|
1992-04-13 |
1993-10-14 |
Cassella Ag |
Asparaginsäurederivate, ihre Herstellung und Verwendung
|
AU4540693A
(en)
*
|
1992-06-25 |
1994-01-24 |
G.D. Searle & Co. |
Phenyl amidine alkanoic acids and lactones useful as platelet aggregation inhibitors
|
US5338725A
(en)
*
|
1992-06-30 |
1994-08-16 |
The Research Foundation Of The State University Of New York |
Anti-aggregatory agents for platelets
|
WO1994008962A1
(en)
*
|
1992-10-14 |
1994-04-28 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
US5358956A
(en)
*
|
1992-10-14 |
1994-10-25 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
JP3322878B2
(ja)
*
|
1992-10-14 |
2002-09-09 |
メルク エンド カンパニー インコーポレーテッド |
フィブリノーゲンレセプターアンタゴニスト
|
US5340798A
(en)
*
|
1992-10-14 |
1994-08-23 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
US5648368A
(en)
*
|
1992-12-01 |
1997-07-15 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
DE4301747A1
(de)
*
|
1993-01-23 |
1994-07-28 |
Cassella Ag |
Substituierte Aminoverbindungen, ihre Herstellung und ihre Verwendung
|
US5314902A
(en)
*
|
1993-01-27 |
1994-05-24 |
Monsanto Company |
Urea derivatives useful as platelet aggregation inhibitors
|
EP0682529B2
(de)
*
|
1993-02-09 |
2005-12-28 |
Biogen Idec MA, Inc. |
Antikörper zur behandlung von insulinabhängigem diabetes
|
US5409939A
(en)
*
|
1993-02-12 |
1995-04-25 |
G. D. Searle & Co. |
Phenyl amidine thio derivatives useful as platelet aggregation inhibitors
|
US5614539A
(en)
*
|
1993-03-15 |
1997-03-25 |
G. D. Searle & Co. |
Urea compounds which are useful as platelet aggregation inhibitors
|
US5441952A
(en)
*
|
1993-04-05 |
1995-08-15 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
US5334596A
(en)
*
|
1993-05-11 |
1994-08-02 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
GB9312315D0
(en)
*
|
1993-06-15 |
1993-07-28 |
Poston Robin |
Leukocyte adhesion assay
|
US5612355A
(en)
*
|
1993-06-23 |
1997-03-18 |
G. D. Searle & Co. |
Phenyl amidine lactones useful as platelet aggregation inhibitors
|
US5397791A
(en)
*
|
1993-08-09 |
1995-03-14 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
TW394760B
(en)
*
|
1993-09-07 |
2000-06-21 |
Hoffmann La Roche |
Novel Carboxamides, process for their preparation and pharmaceutical composition containing the same
|
US5780590A
(en)
*
|
1993-10-15 |
1998-07-14 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
|
BR9407839A
(pt)
*
|
1993-10-15 |
1997-05-13 |
Rhone Poulenc Rorer Pharma |
Composto composição farmacêutica e processo para a prevenção ou tratamento de trombose em um mamífero em necessidade desta terapia
|
US5821241A
(en)
*
|
1994-02-22 |
1998-10-13 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
US6387880B1
(en)
|
1994-10-24 |
2002-05-14 |
G.D. Searle & Co. |
Transdermal N-[N-[5-[4-(aminoiminomethly)phenyl]-1-oxopentyl]-L-α-aspartyl]-L-phenylalainine or its esters and their pharmaceutically acceptable salts
|
US5602155A
(en)
*
|
1995-01-17 |
1997-02-11 |
G. D. Searle & Co. |
Platelet aggregation inhibitors
|
US5639765A
(en)
*
|
1995-01-17 |
1997-06-17 |
G. D. Searle & Co. |
Guanidinoalkyl glycine β-amino acids useful for inhibiting bone loss
|
US5719144A
(en)
*
|
1995-02-22 |
1998-02-17 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
US5681820A
(en)
*
|
1995-05-16 |
1997-10-28 |
G. D. Searle & Co. |
Guanidinoalkyl glycine β-amino acids useful for inhibiting tumor metastasis
|
US5852045A
(en)
*
|
1995-10-19 |
1998-12-22 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
US5789421A
(en)
*
|
1995-10-26 |
1998-08-04 |
Merck & Co., Inc. |
Fibrinogen receptor antagonist
|
US5780480A
(en)
*
|
1996-02-28 |
1998-07-14 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
US5889023A
(en)
*
|
1996-05-10 |
1999-03-30 |
Merck & Co., Inc. |
Fibrinogen receptor antagonist
|
BR9713141A
(pt)
*
|
1996-11-27 |
2000-02-08 |
Rhone Poulenc Rorer Pharma |
Composição farmcêutica processo e kit para o tratamento ou a prevenção de um quadro fisiológico asociado com um distúrbio isquêmico relacionado com trombose e um paciente, uso de quantidades farmaceuticamente efetivas de um composto com atividade anti-xa e de um composto antagonista de agregação de plaquetas, produto contendo estes compostos, e, uso destes compostos.
|
US5981584A
(en)
*
|
1997-02-06 |
1999-11-09 |
Merck & Co., Inc. |
Fibrinogen receptor antagonist prodrugs
|
US5872122A
(en)
*
|
1997-10-16 |
1999-02-16 |
Monsanto Company |
Pyrimidinylamidino β-amino acid derivatives useful as inhibitors of platelet aggregation
|