DE68908481T3 - In 2-Stellung substituierte Cumaranderivate. - Google Patents

In 2-Stellung substituierte Cumaranderivate.

Info

Publication number
DE68908481T3
DE68908481T3 DE68908481T DE68908481T DE68908481T3 DE 68908481 T3 DE68908481 T3 DE 68908481T3 DE 68908481 T DE68908481 T DE 68908481T DE 68908481 T DE68908481 T DE 68908481T DE 68908481 T3 DE68908481 T3 DE 68908481T3
Authority
DE
Germany
Prior art keywords
lower alkyl
substituted
agent
alkoxycarbonyl
carboxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68908481T
Other languages
English (en)
Other versions
DE68908481D1 (de
DE68908481T2 (de
Inventor
Giichi Goto
Shigenori Ohkawa
Naohisa Fukuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomedica Foscama Industria Chimico Farmaceutica SpA
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15348634&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68908481(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE68908481D1 publication Critical patent/DE68908481D1/de
Publication of DE68908481T2 publication Critical patent/DE68908481T2/de
Application granted granted Critical
Publication of DE68908481T3 publication Critical patent/DE68908481T3/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DE68908481T 1988-06-10 1989-05-30 In 2-Stellung substituierte Cumaranderivate. Expired - Fee Related DE68908481T3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14385988 1988-06-10

Publications (3)

Publication Number Publication Date
DE68908481D1 DE68908481D1 (de) 1993-09-23
DE68908481T2 DE68908481T2 (de) 1993-12-09
DE68908481T3 true DE68908481T3 (de) 1998-07-09

Family

ID=15348634

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68908481T Expired - Fee Related DE68908481T3 (de) 1988-06-10 1989-05-30 In 2-Stellung substituierte Cumaranderivate.

Country Status (6)

Country Link
US (1) US4978761A (de)
EP (1) EP0345593B2 (de)
JP (1) JP2855340B2 (de)
AT (1) ATE93231T1 (de)
CA (1) CA1339505C (de)
DE (1) DE68908481T3 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229482B (it) * 1988-08-01 1991-09-03 Foscama Biomed Chim Farma Acidi (rs) 2 (2,3 diidro 5 idrossi 4,6,7 trimetilbenzofuranil) acetico e 2 (2,3 diidro 5 acilossi 4,6,7 trimetilbenzofuranil) acetici e loro esteri, utili come farmaci mucoregolatori ed antiischemici.
IT1231341B (it) * 1989-08-18 1991-11-28 Foscama Biomed Chim Farma 2,3 diidro 5 ossi 4,6,7 trimetilbenzofurani 2 (rs) sostituiti, utili come farmaci antiossidanti con proprieta' mucoregolatrici e antiischemiche.
US5244918A (en) * 1989-11-17 1993-09-14 Meiji Milk Products Co., Ltd. Benzofuran derivative and pharmaceutical comprising the same as active ingredient
US5091533A (en) * 1990-03-12 1992-02-25 Merck Frosst Canada, Inc. 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
EP0457716A1 (de) * 1990-04-20 1991-11-21 Ciba-Geigy Ag Naphthalinderivate
DE4027573A1 (de) * 1990-08-31 1992-03-05 Basf Ag Neue 2,3-dihydrobenzofurane und verfahren zu ihrer herstellung
TW224461B (de) * 1990-09-18 1994-06-01 Ciba Geigy Ag
IE68675B1 (en) * 1990-11-01 1996-07-10 Takeda Chemical Industries Ltd Aminocoumaran derivatives their production and use
NO301161B1 (no) * 1991-09-25 1997-09-22 Takeda Chemical Industries Ltd Aminocouromanderivater, deres anvendelse og farmasöytiske sammensetninger inneholdende disse
EP0550292A1 (de) * 1992-01-02 1993-07-07 Merrell Dow Pharmaceuticals Inc. Tocopherol-Analog zum Gewebeschutz
US5510373A (en) * 1992-04-06 1996-04-23 Merrell Pharmaceuticals Inc. Cardioprotective agents
NZ251134A (en) * 1992-04-06 1997-06-24 Merrell Dow Pharma 3-carboxy-5-hydroxybenzo[b]furan derivatives and pharmaceutical compositions
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
US5545660A (en) * 1992-04-07 1996-08-13 Merrell Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
TW393475B (en) * 1992-10-16 2000-06-11 Chugai Pharmaceutical Co Ltd 4-alkoxyl-2,6-di-t-butyl phenol derivatives
EP0640609A1 (de) * 1993-08-24 1995-03-01 Ono Pharmaceutical Co., Ltd. Kondensierte Phenolderivate mit Hemmwirkung auf TXA2 Synthetase und 5-Lipoxygenase, und zum Abfangen von Säuerstoffverbindungen
US5750564A (en) * 1995-09-12 1998-05-12 Hellberg; Mark Anti-oxidant esters of non-steroidal anti-inflammatory agents
EP0988289A2 (de) 1997-06-05 2000-03-29 Takeda Pharmaceutical Company Limited Benzofurane und benzothiophene als unterdrücker der neurodegeneration
US6342516B1 (en) 1998-07-31 2002-01-29 Nippon Soda Co., Ltd. Phenylazole compounds, process for producing the same and drugs for hyperlipemia
AU2571400A (en) * 1999-02-23 2000-09-14 Chugai Seiyaku Kabushiki Kaisha Seam soft capsule preparations containing dihydrobenzofuran derivative
AU6594900A (en) * 1999-08-20 2001-03-19 Takeda Chemical Industries Ltd. Tricyclic dihydrobenzofuran derivatives, process for the preparation thereof andagents
AU2004230369B2 (en) 2003-04-14 2008-01-10 Nippon Soda Co., Ltd Diamine derivative, production process, and antioxidizing drug
JP2005008631A (ja) * 2003-05-29 2005-01-13 New Industry Research Organization ベンゾフラン化合物、およびそれを含有してなる医薬組成物
CN108530405A (zh) * 2018-05-08 2018-09-14 南京晓庄学院 非金属路易斯酸催化烯烃分子内加成c-o键合成苯并呋喃衍生物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2421811A (en) * 1939-07-14 1947-06-10 Univ Minnesota Process for producing chroman compounds
US2318895A (en) * 1939-07-14 1943-05-11 Univ Minnesota Biologically active product for controlling procreative metabolism
US2411942A (en) * 1942-01-10 1946-12-03 Univ Minnesota Chemical processes
US2554687A (en) * 1948-01-29 1951-05-29 Universal Oil Prod Co Stabilization of organic compounds
JPS6388173A (ja) * 1986-09-30 1988-04-19 Kuraray Co Ltd ２，３−ジヒドロベンゾフラン誘導体
DE3777366D1 (de) * 1986-12-27 1992-04-16 Takeda Chemical Industries Ltd 2,3-dihydro-cumaron-derivate, ihre herstellung und verwendung.

Also Published As

Publication number Publication date
JP2855340B2 (ja) 1999-02-10
DE68908481D1 (de) 1993-09-23
EP0345593B2 (de) 1998-02-04
CA1339505C (en) 1997-10-21
DE68908481T2 (de) 1993-12-09
US4978761A (en) 1990-12-18
EP0345593A1 (de) 1989-12-13
ATE93231T1 (de) 1993-09-15
JPH0276869A (ja) 1990-03-16
EP0345593B1 (de) 1993-08-18

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S

8339 Ceased/non-payment of the annual fee