ATE93231T1 - In 2-stellung substituierte cumaranderivate. - Google Patents

In 2-stellung substituierte cumaranderivate.

Info

Publication number
ATE93231T1
ATE93231T1 AT89109679T AT89109679T ATE93231T1 AT E93231 T1 ATE93231 T1 AT E93231T1 AT 89109679 T AT89109679 T AT 89109679T AT 89109679 T AT89109679 T AT 89109679T AT E93231 T1 ATE93231 T1 AT E93231T1
Authority
AT
Austria
Prior art keywords
lower alkyl
substituted
agent
alkoxycarbonyl
carboxy
Prior art date
Application number
AT89109679T
Other languages
English (en)
Inventor
Giichi Goto
Shigenori Ohkawa
Naohisa Fukuda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15348634&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE93231(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE93231T1 publication Critical patent/ATE93231T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT89109679T 1988-06-10 1989-05-30 In 2-stellung substituierte cumaranderivate. ATE93231T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14385988 1988-06-10
EP89109679A EP0345593B2 (de) 1988-06-10 1989-05-30 In 2-Stellung substituierte Cumaranderivate

Publications (1)

Publication Number Publication Date
ATE93231T1 true ATE93231T1 (de) 1993-09-15

Family

ID=15348634

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89109679T ATE93231T1 (de) 1988-06-10 1989-05-30 In 2-stellung substituierte cumaranderivate.

Country Status (6)

Country Link
US (1) US4978761A (de)
EP (1) EP0345593B2 (de)
JP (1) JP2855340B2 (de)
AT (1) ATE93231T1 (de)
CA (1) CA1339505C (de)
DE (1) DE68908481T3 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229482B (it) * 1988-08-01 1991-09-03 Foscama Biomed Chim Farma Acidi (rs) 2 (2,3 diidro 5 idrossi 4,6,7 trimetilbenzofuranil) acetico e 2 (2,3 diidro 5 acilossi 4,6,7 trimetilbenzofuranil) acetici e loro esteri, utili come farmaci mucoregolatori ed antiischemici.
IT1231341B (it) * 1989-08-18 1991-11-28 Foscama Biomed Chim Farma 2,3 diidro 5 ossi 4,6,7 trimetilbenzofurani 2 (rs) sostituiti, utili come farmaci antiossidanti con proprieta' mucoregolatrici e antiischemiche.
KR920701190A (ko) * 1989-11-17 1992-08-11 나까야마 히사시 벤조푸란유도체, 그의 제조법 및 이를 유효성분으로 하는 의약
US5091533A (en) * 1990-03-12 1992-02-25 Merck Frosst Canada, Inc. 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
EP0457716A1 (de) * 1990-04-20 1991-11-21 Ciba-Geigy Ag Naphthalinderivate
DE4027573A1 (de) * 1990-08-31 1992-03-05 Basf Ag Neue 2,3-dihydrobenzofurane und verfahren zu ihrer herstellung
TW224461B (de) * 1990-09-18 1994-06-01 Ciba Geigy Ag
TW199152B (de) * 1990-11-01 1993-02-01 Takeda Pharm Industry Co Ltd
NO301161B1 (no) * 1991-09-25 1997-09-22 Takeda Chemical Industries Ltd Aminocouromanderivater, deres anvendelse og farmasöytiske sammensetninger inneholdende disse
EP0550292A1 (de) * 1992-01-02 1993-07-07 Merrell Dow Pharmaceuticals Inc. Tocopherol-Analog zum Gewebeschutz
US5510373A (en) * 1992-04-06 1996-04-23 Merrell Pharmaceuticals Inc. Cardioprotective agents
WO1993020057A1 (en) * 1992-04-06 1993-10-14 Merrell Dow Pharmaceuticals Inc. Novel derivatives of 2,3-dihydro-2,2,4,6,7-pentaalkyl-5-benzofuranols
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
US5545660A (en) * 1992-04-07 1996-08-13 Merrell Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
TW393475B (en) * 1992-10-16 2000-06-11 Chugai Pharmaceutical Co Ltd 4-alkoxyl-2,6-di-t-butyl phenol derivatives
EP0640609A1 (de) * 1993-08-24 1995-03-01 Ono Pharmaceutical Co., Ltd. Kondensierte Phenolderivate mit Hemmwirkung auf TXA2 Synthetase und 5-Lipoxygenase, und zum Abfangen von Säuerstoffverbindungen
US5750564A (en) * 1995-09-12 1998-05-12 Hellberg; Mark Anti-oxidant esters of non-steroidal anti-inflammatory agents
CA2291026A1 (en) 1997-06-05 1998-12-10 Takeda Chemical Industries, Ltd. Heterocyclic compounds, their production and use
WO2000006550A1 (en) 1998-07-31 2000-02-10 Nippon Soda Co., Ltd. Phenylazole compounds, process for producing the same and drugs for hyperlipemia
EP1172104A4 (de) * 1999-02-23 2002-11-27 Chugai Pharmaceutical Co Ltd Zubereitungen aus weichen steckkapselen die dihydrobenzofuranderivate enthalten
EP1211253B1 (de) * 1999-08-20 2004-10-13 Takeda Chemical Industries, Ltd. Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel
US7652155B2 (en) 2003-04-14 2010-01-26 Nippon Soda Co., Ltd. Diamine derivative, production process therefor and antioxidant
JP2005008631A (ja) * 2003-05-29 2005-01-13 New Industry Research Organization ベンゾフラン化合物、およびそれを含有してなる医薬組成物
CN108530405A (zh) * 2018-05-08 2018-09-14 南京晓庄学院 非金属路易斯酸催化烯烃分子内加成c-o键合成苯并呋喃衍生物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2421811A (en) * 1939-07-14 1947-06-10 Univ Minnesota Process for producing chroman compounds
US2318895A (en) * 1939-07-14 1943-05-11 Univ Minnesota Biologically active product for controlling procreative metabolism
US2411942A (en) * 1942-01-10 1946-12-03 Univ Minnesota Chemical processes
US2554687A (en) * 1948-01-29 1951-05-29 Universal Oil Prod Co Stabilization of organic compounds
JPS6388173A (ja) * 1986-09-30 1988-04-19 Kuraray Co Ltd ２，３−ジヒドロベンゾフラン誘導体
DE3777366D1 (de) * 1986-12-27 1992-04-16 Takeda Chemical Industries Ltd 2,3-dihydro-cumaron-derivate, ihre herstellung und verwendung.

Also Published As

Publication number Publication date
EP0345593A1 (de) 1989-12-13
US4978761A (en) 1990-12-18
DE68908481D1 (de) 1993-09-23
CA1339505C (en) 1997-10-21
EP0345593B2 (de) 1998-02-04
JP2855340B2 (ja) 1999-02-10
DE68908481T2 (de) 1993-12-09
DE68908481T3 (de) 1998-07-09
JPH0276869A (ja) 1990-03-16
EP0345593B1 (de) 1993-08-18

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties