DE68908320D1 - Enterische beschichtung und ihre herstellung. - Google Patents

Enterische beschichtung und ihre herstellung.

Info

Publication number
DE68908320D1
DE68908320D1 DE8989309801T DE68908320T DE68908320D1 DE 68908320 D1 DE68908320 D1 DE 68908320D1 DE 8989309801 T DE8989309801 T DE 8989309801T DE 68908320 T DE68908320 T DE 68908320T DE 68908320 D1 DE68908320 D1 DE 68908320D1
Authority
DE
Germany
Prior art keywords
solution
production
weight percent
enteric coating
enteric film
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989309801T
Other languages
English (en)
Other versions
DE68908320T2 (de
Inventor
Shunichi Itoh
Hiroyoshi Koyama
Shin-Ichiro Hirai
Toshio Kashihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE68908320D1 publication Critical patent/DE68908320D1/de
Application granted granted Critical
Publication of DE68908320T2 publication Critical patent/DE68908320T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polarising Elements (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
DE89309801T 1988-09-27 1989-09-26 Enterische Beschichtung und ihre Herstellung. Expired - Fee Related DE68908320T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24354288 1988-09-27

Publications (2)

Publication Number Publication Date
DE68908320D1 true DE68908320D1 (de) 1993-09-16
DE68908320T2 DE68908320T2 (de) 1994-02-24

Family

ID=17105427

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89309801T Expired - Fee Related DE68908320T2 (de) 1988-09-27 1989-09-26 Enterische Beschichtung und ihre Herstellung.

Country Status (10)

Country Link
EP (1) EP0361873B1 (de)
KR (1) KR0134089B1 (de)
AT (1) ATE92753T1 (de)
AU (1) AU619047B2 (de)
CA (1) CA1337274C (de)
DE (1) DE68908320T2 (de)
DK (1) DK473989A (de)
ES (1) ES2058545T3 (de)
IE (1) IE64124B1 (de)
NZ (1) NZ230764A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5124600A (en) * 1999-04-26 2000-11-10 Imperial Sensus, L.L.C. Granular delivery system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3390049A (en) * 1964-12-23 1968-06-25 Smith Kline French Lab Pharmaceutical tablets coated with wax-free ammonia solubilized water soluble shellac
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
DE3234331C2 (de) * 1982-09-16 1986-06-05 A. Nattermann & Cie GmbH, 5000 Köln Verfahren und Lösungen zum Beschichten von Gelatinekapseln mit magensaftresistenten Überzügen
JPH01500589A (ja) * 1986-03-21 1989-03-01 ユーラシアム　ラボラトリーズ　インコーポレーテツド 薬剤組成物
JPS6327424A (ja) * 1986-07-17 1988-02-05 Shionogi & Co Ltd 徐放性製剤およびその製造法

Also Published As

Publication number Publication date
EP0361873A3 (de) 1991-01-30
DK473989A (da) 1990-03-28
DK473989D0 (da) 1989-09-26
ATE92753T1 (de) 1993-08-15
AU4233089A (en) 1990-04-05
KR900004324A (ko) 1990-04-12
IE64124B1 (en) 1995-07-12
KR0134089B1 (ko) 1998-04-22
AU619047B2 (en) 1992-01-16
IE893074L (en) 1990-03-27
DE68908320T2 (de) 1994-02-24
NZ230764A (en) 1991-01-29
EP0361873B1 (de) 1993-08-11
ES2058545T3 (es) 1994-11-01
EP0361873A2 (de) 1990-04-04
CA1337274C (en) 1995-10-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP

8339 Ceased/non-payment of the annual fee