DE68907873D1 - Arylessigsaeuremonoester, deren herstellung und verwendung. - Google Patents
Arylessigsaeuremonoester, deren herstellung und verwendung.Info
- Publication number
- DE68907873D1 DE68907873D1 DE8989313075T DE68907873T DE68907873D1 DE 68907873 D1 DE68907873 D1 DE 68907873D1 DE 8989313075 T DE8989313075 T DE 8989313075T DE 68907873 T DE68907873 T DE 68907873T DE 68907873 D1 DE68907873 D1 DE 68907873D1
- Authority
- DE
- Germany
- Prior art keywords
- hydrogen
- optionally substituted
- methyl
- protecting group
- single bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- UUFQTNFCRMXOAE-UHFFFAOYSA-N 1-methylmethylene Chemical compound C[CH] UUFQTNFCRMXOAE-UHFFFAOYSA-N 0.000 abstract 1
- 101100167062 Caenorhabditis elegans chch-3 gene Proteins 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229930014626 natural product Natural products 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/753—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP31573088 | 1988-12-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68907873D1 true DE68907873D1 (de) | 1993-09-02 |
DE68907873T2 DE68907873T2 (de) | 1993-11-11 |
Family
ID=18068843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE89313075T Expired - Fee Related DE68907873T2 (de) | 1988-12-14 | 1989-12-14 | Arylessigsäuremonoester, deren Herstellung und Verwendung. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5117039A (de) |
EP (1) | EP0373931B1 (de) |
KR (1) | KR0144685B1 (de) |
AT (1) | ATE92032T1 (de) |
DE (1) | DE68907873T2 (de) |
ES (1) | ES2058557T3 (de) |
HK (1) | HK1003786A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69223603T2 (de) * | 1991-06-19 | 1998-04-09 | Shionogi Seiyaku Kk | Optisch aktives zwischenprodukt und dessen herstellung |
US6727277B1 (en) | 2002-11-12 | 2004-04-27 | Kansas State University Research Foundation | Compounds affecting cholesterol absorption |
WO2011141934A1 (en) | 2010-05-13 | 2011-11-17 | Matrix Laboratories Ltd. | An improved process for the preparation of an intermediate of hmg-coa reductase inhibitors |
CA2857078A1 (en) | 2011-11-28 | 2013-06-06 | Mylan Laboratories Ltd | Process for producing chiral statin side chain intermediates employing candida/antarctica lipase b |
CN103408580B (zh) * | 2013-06-03 | 2014-11-19 | 南京欧信医药技术有限公司 | 一种他汀类药物合成中间体的制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT257569B (de) * | 1965-05-06 | 1967-10-10 | Kwizda Fa F Johann | Verfahren zur Herstellung von bicyclischen oder polycyclischen vicinalen Dicarbonsäuren der trans Konfiguration und deren Derivaten |
NZ218115A (en) * | 1985-11-18 | 1990-02-26 | Shionogi & Co | Bicyclic sulphonamides and pharmaceutical compositions |
-
1989
- 1989-12-07 US US07/447,518 patent/US5117039A/en not_active Expired - Fee Related
- 1989-12-14 DE DE89313075T patent/DE68907873T2/de not_active Expired - Fee Related
- 1989-12-14 AT AT89313075T patent/ATE92032T1/de not_active IP Right Cessation
- 1989-12-14 KR KR1019890018555A patent/KR0144685B1/ko not_active IP Right Cessation
- 1989-12-14 EP EP89313075A patent/EP0373931B1/de not_active Expired - Lifetime
- 1989-12-14 ES ES89313075T patent/ES2058557T3/es not_active Expired - Lifetime
-
1998
- 1998-04-04 HK HK98102875A patent/HK1003786A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5117039A (en) | 1992-05-26 |
ES2058557T3 (es) | 1994-11-01 |
DE68907873T2 (de) | 1993-11-11 |
HK1003786A1 (en) | 1998-11-06 |
ATE92032T1 (de) | 1993-08-15 |
EP0373931A3 (de) | 1991-05-15 |
EP0373931A2 (de) | 1990-06-20 |
EP0373931B1 (de) | 1993-07-28 |
KR0144685B1 (ko) | 1998-07-15 |
KR900009533A (ko) | 1990-07-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2867089A (en) | (cycloalkylamino)methylenebis(phosphonic acid) and medicines containing the same as an active ingredient | |
ATE99281T1 (de) | Verfahren zur herstellung von 7-substituierten hept-6-en- und heptansaeuren und derivaten davon. | |
NO940009D0 (no) | Pyrazolopyrimidin og pyrimidinyl-bisfosfonsyreestere som anti-inf lammatoriske midler | |
ATE60763T1 (de) | Pyrrolidinylamidesterderivate mit antiprolylendopeptidaseaktivitaet, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen. | |
DE59407431D1 (de) | Verwendung aromatischer Carbonsäurederivate zur Herstellung von pharmazeutischen Präparaten | |
ATE138571T1 (de) | Verwendung von dioxabicyclo (3.3.0>octane derivaten zur herstellung eines arzneimittels zur hemmung des cholesterinmetabolismus. | |
ATE122042T1 (de) | Pyrazoloisoquinoline-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. | |
DE68901105D1 (de) | Alkensaeurederivate. | |
DE68907873D1 (de) | Arylessigsaeuremonoester, deren herstellung und verwendung. | |
WO1993009111A3 (en) | Novel methods for the preparation of glycerol carbonate esters | |
DE69008070D1 (de) | Verfahren zur Herstellung eines alpha-Ketocarbonsäureester. | |
DE69228541D1 (de) | Chinasäurederivate und Verfahren zur Herstellung von Chinasäurederivaten | |
HK1003785A1 (en) | Mono esters of dicarboxylic acids their preparation and use | |
HUT62855A (en) | Process for producing glycerol derivatives and pharmaceutical compositions comprising same | |
DE69119921D1 (de) | Herstellung von höheren Alkylestern von Carbonsäure | |
IT1238679B (it) | Derivato otticamente attivo dell'acido d-2-(6-metossi-2-naftil)- propionico e composizioni farmaceutiche che lo contengono | |
DE69214280D1 (de) | Thiocarbamat-sulfo-oxid enthaltende zubereitung zur abschreckung gegen ethanoleinnahme | |
JPS6456648A (en) | Optically active benzene derivative, production thereof and liquid crystal material comprising said derivative as active ingredient | |
AU628051B2 (en) | Macrolide compounds | |
IT1229846B (it) | Esteri di catecolammine. | |
EP0338494A3 (de) | 3-Anilino-2-hydroxycarbonyl-4-thiophenessigsäuren | |
ES2095831T3 (es) | Acidos tetrahidro-4-fenilimino-3-tiofeno-aceticos. | |
GR3027684T3 (en) | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acids, esters and salts thereof, and intermediates used in this method | |
ATE100817T1 (de) | Herstellung von optisch aktiven 2-oxoimidazolidin-derivaten. | |
DE3775721D1 (de) | Verfahren zur herstellung von veretherten 3-hydroxyvaleriansaeureestern. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |