DE68907406D1 - Deprenyl zur systemischen transdermalen anwendung. - Google Patents

Deprenyl zur systemischen transdermalen anwendung.

Info

Publication number
DE68907406D1
DE68907406D1 DE8989903719T DE68907406T DE68907406D1 DE 68907406 D1 DE68907406 D1 DE 68907406D1 DE 8989903719 T DE8989903719 T DE 8989903719T DE 68907406 T DE68907406 T DE 68907406T DE 68907406 D1 DE68907406 D1 DE 68907406D1
Authority
DE
Germany
Prior art keywords
deprenyl
transdermal use
systemic transdermal
systemic
transdermal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE8989903719T
Other languages
English (en)
Other versions
DE68907406T2 (de
Inventor
Manfred Karobath
Joerg Reinhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Somerset Pharmaceuticals Inc
Original Assignee
Somerset Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10634325&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68907406(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Somerset Pharmaceuticals Inc filed Critical Somerset Pharmaceuticals Inc
Application granted granted Critical
Publication of DE68907406D1 publication Critical patent/DE68907406D1/de
Publication of DE68907406T2 publication Critical patent/DE68907406T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE89903719T 1988-03-29 1989-03-18 Deprenyl zur systemischen transdermalen anwendung. Revoked DE68907406T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888807504A GB8807504D0 (en) 1988-03-29 1988-03-29 Improvements in/relating to organic compounds

Publications (2)

Publication Number Publication Date
DE68907406D1 true DE68907406D1 (de) 1993-08-05
DE68907406T2 DE68907406T2 (de) 1993-10-14

Family

ID=10634325

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89903719T Revoked DE68907406T2 (de) 1988-03-29 1989-03-18 Deprenyl zur systemischen transdermalen anwendung.

Country Status (18)

Country Link
EP (1) EP0404807B1 (de)
JP (1) JP2533211B2 (de)
KR (1) KR0136870B1 (de)
AU (1) AU630088B2 (de)
CA (1) CA1336071C (de)
DE (1) DE68907406T2 (de)
ES (1) ES2013129A6 (de)
FI (1) FI895681A0 (de)
GB (1) GB8807504D0 (de)
GR (1) GR1003711B (de)
HU (1) HU207441B (de)
IE (1) IE62955B1 (de)
IL (1) IL89748A (de)
MY (1) MY105121A (de)
NZ (1) NZ228467A (de)
PT (1) PT90120B (de)
WO (1) WO1989009051A1 (de)
ZA (1) ZA892321B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861800A (en) * 1987-08-18 1989-08-29 Buyske Donald A Method for administering the drug deprenyl so as to minimize the danger of side effects
HU209605B (en) * 1991-04-15 1994-09-28 Chinoin Gyogyszer Es Vegyeszet Process for production of wather-free transdermal preparation
EP0593807A1 (de) * 1992-10-22 1994-04-27 LTS Lohmann Therapie-Systeme GmbH & Co. KG Transdermales Pflaster zur Abgabe von basischen, flüchtigen pharmazeutischen Wirkstoffen und Verfahren zu ihrer Herstellung
HUT63579A (en) * 1991-12-20 1993-09-28 Chinoin Gyogyszer Es Vegyeszet Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes
US5242950A (en) * 1992-04-23 1993-09-07 Somerset Pharmaceuticals, Inc. Treatment of macular degeneration
ES2164286T3 (es) * 1993-04-20 2002-02-16 Hexal Ag Emplasto con sustancias activas.
PT762877E (pt) 1994-06-03 2001-08-30 Thejmde Trust Arilalquilaminas meta-substituidas e suas aplicacoes terapeuticas e de diagnostico
HU223475B1 (hu) * 1994-10-24 2004-07-28 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Selegilint tartalmazó liposzoma-készítmény és eljárás ennek előállítására
US6033682A (en) 1995-01-13 2000-03-07 Somerset Pharmaceuticals, Inc. S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
US6299901B1 (en) 1995-01-13 2001-10-09 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
US6348208B1 (en) 1995-01-13 2002-02-19 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
US6319954B1 (en) 1995-01-13 2001-11-20 Somerset Pharmaceuticals, Inc. S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions
US6316022B1 (en) 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
CA2223588C (en) 1995-06-07 2004-01-06 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
DE19533089C1 (de) 1995-09-07 1997-05-22 Hexal Ag Tacrin-Pflaster
DE19533772C1 (de) * 1995-09-12 1998-01-02 Hexal Ag Tacrin/Selegilin-Pflaster
IL119417A (en) * 1996-10-13 2003-02-12 Moshe Kushnir Pharmaceutical composition for transdermal administration of levodopa for parkinson's disease
US7150881B2 (en) 1997-06-26 2006-12-19 Mylan Technologies, Inc. Adhesive mixture for transdermal delivery of highly plasticizing drugs
WO1999047133A1 (en) 1998-03-16 1999-09-23 Somerset Pharmaceuticals, Inc. Use of selegiline or desmethylselegiline for treating wounds, burns and dermatological damage
DE19814257A1 (de) 1998-03-31 1999-10-07 Asta Medica Ag Brauseformulierungen
EP1137406B2 (de) 1998-12-07 2008-01-23 J. Dev Limited Pflaster zur transdermalen applikation von flüchtigen, flüssigen wirkstoffen
AU2002354017B2 (en) 2001-11-05 2007-08-16 Krele Pharmaceuticals, Inc. Compositions and methods for increasing compliance with therapies using aldehyde dehydrogenase inhibitors and treating alcoholism
DE10338174A1 (de) 2003-08-20 2005-03-24 Lts Lohmann Therapie-Systeme Ag Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
RU2404750C2 (ru) 2004-11-23 2010-11-27 Адамас Фармасьютикалс, Инк. Композиция, содержащая основу или покрытие для замедленного высвобождения и антагонист nmda рецептора, способ введения такого nmda антагониста субъекту
EP1874282B1 (de) 2005-04-06 2010-09-15 Adamas Pharmaceuticals, Inc. Verfahren und zusammensetzungen zur behandlung von zns-erkrankungen
US7846445B2 (en) 2005-09-27 2010-12-07 Amunix Operating, Inc. Methods for production of unstructured recombinant polymers and uses thereof
US7855279B2 (en) 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
PT2158908E (pt) * 2007-06-21 2013-05-07 Fujimoto Co Ltd Composição para administração transdérmica
EP2185701A4 (de) 2007-08-15 2011-03-02 Amunix Operating Inc Zusammensetzungen und verfahren zur veränderung von eigenschaften biologisch aktiver polypeptide
SI2393828T1 (sl) 2009-02-03 2017-01-31 Amunix Operating Inc. Podaljšani rekombinantni polipetidi in sestavki, ki jih obsegajo
US8716448B2 (en) 2009-02-03 2014-05-06 Amunix Operating Inc. Coagulation factor VII compositions and methods of making and using same
JP5839597B2 (ja) 2009-06-08 2016-01-06 アムニクス オペレーティング インコーポレイテッド グルコース調節ポリペプチド並びにその作成及び使用方法
DK2440241T3 (en) 2009-06-08 2017-10-02 Amunix Operating Inc GROWTH HORMON POLYPEPTIDES AND PROCEDURES FOR PREPARING AND USING THEREOF
CN102883601A (zh) 2009-12-02 2013-01-16 阿达玛斯医药公司 金刚烷胺组合物及其使用方法
DE102010024105A1 (de) * 2010-06-17 2011-12-22 Grünenthal GmbH Transdermale Verabreichung von Memantin
DK2822577T3 (en) 2012-02-15 2019-04-01 Bioverativ Therapeutics Inc RECOMBINANT FACTOR VIII PROTEINS
EP3564260B1 (de) 2012-02-15 2022-10-19 Bioverativ Therapeutics Inc. Faktor-viii-zusammensetzungen und verfahren zur herstellung und verwendung davon
US10154971B2 (en) 2013-06-17 2018-12-18 Adamas Pharma, Llc Methods of administering amantadine
TWI667255B (zh) 2013-08-14 2019-08-01 美商生物化學醫療公司 因子viii-xten融合物及其用途
EP3331608A4 (de) 2015-08-03 2019-05-01 Bioverativ Therapeutics Inc. Faktor-ix-fusionsproteine und verfahren zur herstellung und verwendung davon
WO2018071656A1 (en) 2016-10-14 2018-04-19 Knowles Enterprises Inc. Formulations for treatment of migraines
WO2018200885A1 (en) 2017-04-26 2018-11-01 Neurocentria, Inc. Magnesium compositions and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0139127A1 (de) * 1983-08-22 1985-05-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Vorrichtung zur transdermalen Abgabe von Heilmitteln und ihre Herstellung
IL72684A (en) * 1984-08-14 1989-02-28 Israel State Pharmaceutical compositions for controlled transdermal delivery of cholinergic or anticholinergic basic drugs
US4568343A (en) * 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
ATE55245T1 (de) * 1986-04-16 1990-08-15 Asta Pharma Ag Synergistische kombination von amantadin und selegilin.

Also Published As

Publication number Publication date
KR900700089A (ko) 1990-08-11
AU3290089A (en) 1989-10-16
GB8807504D0 (en) 1988-05-05
WO1989009051A1 (en) 1989-10-05
DE68907406T2 (de) 1993-10-14
IE890921L (en) 1989-09-29
KR0136870B1 (ko) 1998-04-25
EP0404807A1 (de) 1991-01-02
EP0404807B1 (de) 1993-06-30
JP2533211B2 (ja) 1996-09-11
IL89748A (en) 1993-07-08
HU207441B (en) 1993-04-28
HU892559D0 (en) 1990-01-28
GR890100190A (el) 1990-01-19
FI895681A0 (fi) 1989-11-28
HUT55220A (en) 1991-05-28
CA1336071C (en) 1995-06-27
GR1003711B (el) 2001-10-25
PT90120B (pt) 1994-06-30
MY105121A (en) 1994-08-30
AU630088B2 (en) 1992-10-22
IE62955B1 (en) 1995-02-20
PT90120A (pt) 1989-11-10
NZ228467A (en) 1991-12-23
ZA892321B (en) 1990-12-28
JPH02503677A (ja) 1990-11-01
ES2013129A6 (es) 1990-04-16

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation