DE68906261D1 - Somatropine. - Google Patents

Somatropine.

Info

Publication number
DE68906261D1
DE68906261D1 DE8989910508T DE68906261T DE68906261D1 DE 68906261 D1 DE68906261 D1 DE 68906261D1 DE 8989910508 T DE8989910508 T DE 8989910508T DE 68906261 T DE68906261 T DE 68906261T DE 68906261 D1 DE68906261 D1 DE 68906261D1
Authority
DE
Germany
Prior art keywords
somatropine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989910508T
Other languages
English (en)
Other versions
DE68906261T2 (de
Inventor
Gwen Krivi
Michael Schlittler
Bernard Violand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Application granted granted Critical
Publication of DE68906261D1 publication Critical patent/DE68906261D1/de
Publication of DE68906261T2 publication Critical patent/DE68906261T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormones [GH] (Somatotropin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
DE89910508T 1988-08-29 1989-08-28 Somatropine. Expired - Lifetime DE68906261T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/237,358 US5089473A (en) 1988-08-29 1988-08-29 Somatotropin variants and their use

Publications (2)

Publication Number Publication Date
DE68906261D1 true DE68906261D1 (de) 1993-06-03
DE68906261T2 DE68906261T2 (de) 1993-11-11

Family

ID=22893393

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89910508T Expired - Lifetime DE68906261T2 (de) 1988-08-29 1989-08-28 Somatropine.

Country Status (14)

Country Link
US (1) US5089473A (de)
EP (2) EP0363342A1 (de)
JP (1) JP2784232B2 (de)
AU (1) AU614879B2 (de)
BG (1) BG60324B2 (de)
BR (1) BR8907068A (de)
CA (1) CA1340122C (de)
DE (1) DE68906261T2 (de)
ES (2) ES2054096T3 (de)
HU (1) HUT54409A (de)
IL (1) IL91457A (de)
NZ (1) NZ230458A (de)
WO (1) WO1990002182A1 (de)
ZA (1) ZA896557B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631227A (en) * 1985-09-18 1997-05-20 The Upjohn Company Somatotropin analogs
US5130422A (en) * 1988-08-29 1992-07-14 Monsanto Company Variant somatotropin-encoding DNA
IE912345A1 (en) * 1990-08-03 1992-02-12 Pharmacia Ab Treatment of human lactation failure
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
GB9823071D0 (en) * 1998-10-21 1998-12-16 Affibody Technology Ab A method
US6238706B1 (en) 1999-05-06 2001-05-29 Grofish L.L.C. Method of stimulating growth in aquatic animals using growth hormones
AU2003263552A1 (en) * 2002-09-09 2004-03-29 Nautilus Biotech Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
US8592555B2 (en) 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
SG195555A1 (en) 2008-12-24 2013-12-30 Emd Millipore Corp Caustic stable chromatography ligands
US8680050B2 (en) * 2009-02-03 2014-03-25 Amunix Operating Inc. Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
US8703717B2 (en) 2009-02-03 2014-04-22 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
CN102348715B (zh) 2009-02-03 2017-12-08 阿穆尼克斯运营公司 延伸重组多肽和包含该延伸重组多肽的组合物
US9849188B2 (en) 2009-06-08 2017-12-26 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
SG186552A1 (en) 2011-06-08 2013-01-30 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79124B (de) 1982-12-22 1984-10-02 Genentech Inc
ES8800957A1 (es) 1985-02-22 1987-12-01 Monsanto Co Un metodo para la solubilizacion y renaturalizacion de proteina somatotropina
US5037806A (en) * 1985-02-22 1991-08-06 Monsanto Company Biologically active method using somatotropins
JPS63500941A (ja) * 1985-09-18 1988-04-07 ジ・アップジョン・カンパニ− 選択的脱アミノ化による哺乳動物ソマトトロピンの生物学的活性の増強
AU597951B2 (en) 1986-03-27 1990-06-14 Monsanto Company Enhanced protein production in bacteria by employing a novel ribosome binding site
ES2019874B3 (es) * 1986-10-08 1991-07-16 Upjohn Co Bioactividad mejorada de somatotropina de mamiferos mediante desamidacion selectiva.
EP0355460B1 (de) * 1988-08-24 2000-12-27 American Cyanamid Company Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung

Also Published As

Publication number Publication date
AU4316089A (en) 1990-03-23
EP0403601B1 (de) 1993-04-28
NZ230458A (en) 1991-11-26
WO1990002182A1 (en) 1990-03-08
IL91457A0 (en) 1990-04-29
BG60324B2 (en) 1994-05-27
ES2016069A4 (es) 1990-10-16
DE68906261T2 (de) 1993-11-11
HUT54409A (en) 1991-02-28
EP0363342A1 (de) 1990-04-11
BR8907068A (pt) 1990-10-02
ES2054096T3 (es) 1994-08-01
EP0403601A1 (de) 1990-12-27
ZA896557B (en) 1990-08-29
AU614879B2 (en) 1991-09-12
JP2784232B2 (ja) 1998-08-06
IL91457A (en) 1994-04-12
JPH03501856A (ja) 1991-04-25
US5089473A (en) 1992-02-18
CA1340122C (en) 1998-11-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee