DE68905219T2 - 2-substituierte 2-cyclopentenone. - Google Patents

2-substituierte 2-cyclopentenone.

Info

Publication number
DE68905219T2
DE68905219T2 DE8989303868T DE68905219T DE68905219T2 DE 68905219 T2 DE68905219 T2 DE 68905219T2 DE 8989303868 T DE8989303868 T DE 8989303868T DE 68905219 T DE68905219 T DE 68905219T DE 68905219 T2 DE68905219 T2 DE 68905219T2
Authority
DE
Germany
Prior art keywords
cyclopentenone
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989303868T
Other languages
English (en)
Other versions
DE68905219D1 (de
Inventor
Satoshi Sugiura
Atsuo Hazato
Toru Minoshima
Yoshinori Kato
Yasuko Koshihara
Seizi Kurozumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of DE68905219D1 publication Critical patent/DE68905219D1/de
Application granted granted Critical
Publication of DE68905219T2 publication Critical patent/DE68905219T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
DE8989303868T 1988-04-19 1989-04-19 2-substituierte 2-cyclopentenone. Expired - Fee Related DE68905219T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9468788 1988-04-19
JP1303689 1989-01-24

Publications (2)

Publication Number Publication Date
DE68905219D1 DE68905219D1 (de) 1993-04-15
DE68905219T2 true DE68905219T2 (de) 1993-06-24

Family

ID=26348755

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989303868T Expired - Fee Related DE68905219T2 (de) 1988-04-19 1989-04-19 2-substituierte 2-cyclopentenone.

Country Status (5)

Country Link
US (1) US5116869A (de)
EP (1) EP0338796B1 (de)
AU (1) AU615534B2 (de)
CA (1) CA1332603C (de)
DE (1) DE68905219T2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216183A (en) * 1988-04-19 1993-06-01 Teijin Limited Cyclopentanone/cyclopentenone derivative
US5338844A (en) * 1989-10-19 1994-08-16 Teijin Limited 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient
IT1289250B1 (it) 1996-12-13 1998-09-29 Consiglio Nazionale Ricerche Impiego di 2 ciclopenten 1-one e suoi derivati come inibitori del fattore nf-kb
US20050020687A1 (en) * 1996-01-14 2005-01-27 Consiglio Nazionale Ricerche Methods of treating inflammatory and viral disorders by administering cyclopentenone compounds
CA2263563C (en) * 1996-09-27 2003-12-30 Takara Shuzo Co., Ltd. Cyclopentenones, process for preparing the same, and the use thereof
CA2275595C (en) 1996-12-20 2003-08-05 Pfizer Inc. Prevention and treatment of skeletal disorder with ep2 receptor subtype selective prostaglandin e2 agonists
GB9929702D0 (en) * 1999-12-16 2000-02-09 Charterhouse Therapeutics Ltd Chemical compounds and their uses

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180672A (en) * 1976-08-13 1979-12-25 Teijin Limited 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom
JPS5390246A (en) * 1976-12-27 1978-08-08 Sagami Chem Res Center 2-hydroxymethyl-3,4-di-substd-cyclopentanone derivs. and process for their preparation
JPS5615236A (en) * 1979-07-17 1981-02-14 Sumitomo Chem Co Ltd Production of cyclopentenolone
JPS58216155A (ja) * 1982-06-10 1983-12-15 Ono Pharmaceut Co Ltd 新規なプロスタグランジンｄ類似化合物
JPS5959646A (ja) * 1982-09-27 1984-04-05 Fujisawa Pharmaceut Co Ltd クラブロン誘導体
JPS604129A (ja) * 1983-06-22 1985-01-10 Fujisawa Pharmaceut Co Ltd 抗腫瘍剤
JPS59184158A (ja) * 1983-04-02 1984-10-19 Fujisawa Pharmaceut Co Ltd クラブロン誘導体
EP0106576B1 (de) * 1982-10-07 1988-03-09 Teijin Limited Neue 5-gliedrige Ringverbindungen, ein Verfahren zu ihrer Herstellung und ihre pharmazeutische Anwendung
EP0131441B1 (de) * 1983-07-06 1989-10-18 Teijin Limited 5-Alkyliden-2-halo-4 substituierte 2-Cyclopentenonen, und ein Verfahren zu ihrer Herstellung
EP0172233A4 (de) * 1984-02-14 1986-07-29 Univ Hawaii Punaglandine und deren verwendung als arzneimittel.
DE3586085D1 (de) * 1984-10-22 1992-06-25 Teijin Ltd Antitumor-4-hydroxy-2-zyklopentenonen.
JPH0643360B2 (ja) * 1985-10-22 1994-06-08 帝人株式会社 ４―ヒドロキシ―２―シクロペンテノン類及び薬剤組成物
JPS63502277A (ja) * 1986-01-08 1988-09-01 ハ−バ−　ブランチ　オ−シヤノグラフイツク　インスチチユ−シヨン　インコ−ポレイテツド 抗腫瘍シクロヘキサノン組成物およびその誘導体
FR2592941B1 (fr) * 1986-01-14 1988-05-06 Usinor Aciers Bruleur de prechauffage

Also Published As

Publication number Publication date
DE68905219D1 (de) 1993-04-15
AU3315089A (en) 1989-10-26
AU615534B2 (en) 1991-10-03
EP0338796B1 (de) 1993-03-10
CA1332603C (en) 1994-10-18
EP0338796A3 (en) 1990-05-16
US5116869A (en) 1992-05-26
EP0338796A2 (de) 1989-10-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee