DE68904578D1 - Enzym zur alpha-amidierung von c-termini und verfahren zu dessen herstellung. - Google Patents
Enzym zur alpha-amidierung von c-termini und verfahren zu dessen herstellung.Info
- Publication number
- DE68904578D1 DE68904578D1 DE8989302434T DE68904578T DE68904578D1 DE 68904578 D1 DE68904578 D1 DE 68904578D1 DE 8989302434 T DE8989302434 T DE 8989302434T DE 68904578 T DE68904578 T DE 68904578T DE 68904578 D1 DE68904578 D1 DE 68904578D1
- Authority
- DE
- Germany
- Prior art keywords
- peptide
- enzyme
- protein
- alpha
- leu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/17—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced ascorbate as one donor, and incorporation of one atom of oxygen (1.14.17)
- C12Y114/17003—Peptidylglycine monooxygenase (1.14.17.3)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63058187A JP2653820B2 (ja) | 1988-03-14 | 1988-03-14 | アミド化酵素及びその製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68904578D1 true DE68904578D1 (de) | 1993-03-11 |
DE68904578T2 DE68904578T2 (de) | 1993-06-09 |
Family
ID=13077015
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8989302434T Expired - Fee Related DE68904578T2 (de) | 1988-03-14 | 1989-03-13 | Enzym zur alpha-amidierung von c-termini und verfahren zu dessen herstellung. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5360727A (de) |
EP (1) | EP0333399B1 (de) |
JP (1) | JP2653820B2 (de) |
AT (1) | ATE85077T1 (de) |
AU (1) | AU612006B2 (de) |
CA (1) | CA1337860C (de) |
DE (1) | DE68904578T2 (de) |
ES (1) | ES2053978T3 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989012096A1 (en) * | 1988-05-30 | 1989-12-14 | Shiseido Co. Ltd. | C-terminus amidation enzyme composition, process for its preparation and its use |
DK0465404T3 (da) * | 1990-06-01 | 1995-12-18 | Ciba Geigy Ag | Peptidylhydroxylglycin-N-C-lyase og DNA, som koder derfor |
IT1250689B (it) * | 1991-07-22 | 1995-04-21 | Marco Gerna | Analoghi dell'irudina e procedimento per la loro preparazione |
US6507788B1 (en) | 1999-02-25 | 2003-01-14 | Société de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.) | Rational selection of putative peptides from identified nucleotide, or peptide sequences, of unknown function |
US20080212024A1 (en) * | 2006-09-18 | 2008-09-04 | Lai Shui T | Customized contact lenses for reducing aberrations of the eye |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8314362D0 (en) * | 1983-05-24 | 1983-06-29 | Celltech Ltd | Polypeptide and protein products |
US4708934A (en) * | 1984-09-27 | 1987-11-24 | Unigene Laboratories, Inc. | α-amidation enzyme |
GB8523156D0 (en) * | 1985-09-19 | 1985-10-23 | Celltech Ltd | Polypeptide production |
JPH0775541B2 (ja) * | 1986-06-07 | 1995-08-16 | 壽之 松尾 | C末端アミド化酵素及びその製造方法 |
WO1990002815A1 (en) * | 1988-09-13 | 1990-03-22 | The General Hospital Corporation | Isolation, purification, and characterization of the aminopeptidases: mas ii and mas iii |
AU4213489A (en) * | 1988-09-13 | 1990-04-02 | General Hospital Corporation, The | Isolation, purification, and characterization of the aminopeptidases: ap1 and ap122 |
-
1988
- 1988-03-14 JP JP63058187A patent/JP2653820B2/ja not_active Expired - Fee Related
-
1989
- 1989-03-08 AU AU31128/89A patent/AU612006B2/en not_active Ceased
- 1989-03-13 ES ES89302434T patent/ES2053978T3/es not_active Expired - Lifetime
- 1989-03-13 EP EP89302434A patent/EP0333399B1/de not_active Expired - Lifetime
- 1989-03-13 AT AT89302434T patent/ATE85077T1/de not_active IP Right Cessation
- 1989-03-13 DE DE8989302434T patent/DE68904578T2/de not_active Expired - Fee Related
- 1989-03-14 CA CA000593643A patent/CA1337860C/en not_active Expired - Fee Related
-
1992
- 1992-08-03 US US07/921,600 patent/US5360727A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH01231888A (ja) | 1989-09-18 |
ATE85077T1 (de) | 1993-02-15 |
AU612006B2 (en) | 1991-06-27 |
JP2653820B2 (ja) | 1997-09-17 |
EP0333399B1 (de) | 1993-01-27 |
DE68904578T2 (de) | 1993-06-09 |
AU3112889A (en) | 1989-09-14 |
EP0333399A2 (de) | 1989-09-20 |
ES2053978T3 (es) | 1994-08-01 |
EP0333399A3 (en) | 1990-09-05 |
CA1337860C (en) | 1996-01-02 |
US5360727A (en) | 1994-11-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Voorter et al. | Spontaneous peptide bond cleavage in aging alpha-crystallin through a succinimide intermediate. | |
INOMATA et al. | Comparison of low and high calcium requiring forms of the calcium-activated neutral protease (CANP) from rabbit skeletal muscle | |
DE69937036D1 (de) | Verfahren zur Herstellung von L-Aminosäuren | |
ATE9595T1 (de) | Verfahren zur enzymatischen herstellung von peptiden. | |
DE3586773D1 (de) | Verfahren zur beseitigung von n-endaminosaeureresten aus eukaryotpolypeptidanlagen und so erzeugte polypeptide. | |
US5270176A (en) | Method for the selective cleavage of fusion proteins with lysostaphin | |
ATE272109T1 (de) | Rekombinante collagenase typ i aus clostridium histolyticum und ihre verwendung zur isolierung von zellen und zellverbänden | |
ATE102949T1 (de) | Verfahren zur herstellung von retro-inversopeptiden und dessen zwischenprodukte. | |
Hirano et al. | Deblocking and subsequent microsequence analysis of N α-blocked proteins electroblotted onto PVDF membrane | |
DE68904578D1 (de) | Enzym zur alpha-amidierung von c-termini und verfahren zu dessen herstellung. | |
ATE253639T1 (de) | Verfahren zur herstellung von peptiden | |
ATE291088T1 (de) | Immunologisch aktive proteine von borrelia burgdorferi, dafür kodierende nukleinsäuren sowie deren verwendung in testkits und als impfstoffe | |
ATE356145T1 (de) | Polypeptide zur regenerierung des nervensystems | |
DE69732583D1 (de) | Verfahren zur Spaltung eines chimeren Proteins mittels eines 'processing'-Enzyms | |
KR940009329A (ko) | 딕티오스텔륨 디펩티딜아미노펩티다아제 | |
Uitto et al. | Characterization of the precursor forms of the α1 and α2 chains of collagen from matrix-free tendon cells | |
EP0312157A3 (de) | Tetrapeptid-Renin-Inhibitoren mit C-terminalen Aminosäureamiden | |
ATE121456T1 (de) | Klonierung und überexpression von glucose-6- phosphat-dehydrogenase aus leuconostoc dextranicus. | |
AU7809591A (en) | Novel enzyme and dna coding therefor | |
ATE122099T1 (de) | Verfahren zur herstellung von c-terminalen alpha- amidierten peptiden. | |
HUP0002234A2 (hu) | Amin-oxidáz-aktivitású 1-es vaszkuláris adhéziós fehérje (VAP-1) | |
ATE78872T1 (de) | Herstellung von polypeptiden. | |
DE3781832D1 (de) | C-terminal-alpha-amidierendes enzym und verfahren zu dessen herstellung und verwendung. | |
IE62228B1 (en) | A method for the selective cleavage of fusion proteins | |
ATE173831T1 (de) | Methode zur bildung eines aminosäurehydantoinderivats unter verwendung eines n-substituierten ketenimins als aktivator |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |