DE643578T1 - Neue zusammensetzung, die selegilin enthält. - Google Patents
Neue zusammensetzung, die selegilin enthält.Info
- Publication number
- DE643578T1 DE643578T1 DE0643578T DE94911961T DE643578T1 DE 643578 T1 DE643578 T1 DE 643578T1 DE 0643578 T DE0643578 T DE 0643578T DE 94911961 T DE94911961 T DE 94911961T DE 643578 T1 DE643578 T1 DE 643578T1
- Authority
- DE
- Germany
- Prior art keywords
- composition according
- acid
- lubricant
- selegiline
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims 20
- 229960003946 selegiline Drugs 0.000 title claims 9
- MEZLKOACVSPNER-GFCCVEGCSA-N selegiline Chemical compound C#CCN(C)[C@H](C)CC1=CC=CC=C1 MEZLKOACVSPNER-GFCCVEGCSA-N 0.000 title claims 9
- 239000002253 acid Substances 0.000 claims 15
- 239000000314 lubricant Substances 0.000 claims 12
- 150000003839 salts Chemical class 0.000 claims 10
- -1 fatty acid ester Chemical class 0.000 claims 8
- 235000014113 dietary fatty acids Nutrition 0.000 claims 6
- 239000000194 fatty acid Substances 0.000 claims 6
- 229930195729 fatty acid Natural products 0.000 claims 6
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 6
- 239000008158 vegetable oil Substances 0.000 claims 6
- IYETZZCWLLUHIJ-UHFFFAOYSA-N methyl-(1-phenylpropan-2-yl)-prop-2-ynylazanium;chloride Chemical compound Cl.C#CCN(C)C(C)CC1=CC=CC=C1 IYETZZCWLLUHIJ-UHFFFAOYSA-N 0.000 claims 4
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical class CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims 4
- 229960003678 selegiline hydrochloride Drugs 0.000 claims 4
- 239000008247 solid mixture Substances 0.000 claims 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- DMBUODUULYCPAK-UHFFFAOYSA-N 1,3-bis(docosanoyloxy)propan-2-yl docosanoate Chemical group CCCCCCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCCCCCC DMBUODUULYCPAK-UHFFFAOYSA-N 0.000 claims 2
- 239000004135 Bone phosphate Substances 0.000 claims 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical group [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 235000021355 Stearic acid Nutrition 0.000 claims 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 235000012343 cottonseed oil Nutrition 0.000 claims 2
- 239000002385 cottonseed oil Substances 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical group [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims 2
- 150000007524 organic acids Chemical class 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 150000004671 saturated fatty acids Chemical class 0.000 claims 2
- 239000008117 stearic acid Substances 0.000 claims 2
- 239000011975 tartaric acid Substances 0.000 claims 2
- 235000002906 tartaric acid Nutrition 0.000 claims 2
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims 1
- 235000019341 magnesium sulphate Nutrition 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE19939301112A SE9301112D0 (sv) | 1993-04-02 | 1993-04-02 | A new composition |
| PCT/FI1994/000128 WO1994022435A1 (en) | 1993-04-02 | 1994-03-31 | A new composition containing selegiline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE643578T1 true DE643578T1 (de) | 1996-09-19 |
Family
ID=20389464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE0643578T Pending DE643578T1 (de) | 1993-04-02 | 1994-03-31 | Neue zusammensetzung, die selegilin enthält. |
Country Status (8)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5561163A (en) * | 1990-08-31 | 1996-10-01 | Deprenyl Animal Health, Inc. | Treating hearing loss with deprenyl |
| ATE199495T1 (de) * | 1994-12-14 | 2001-03-15 | Enbalt Trading Ltd | Pharmazeutische zubereitung zur direktverpressung |
| GB9426079D0 (en) * | 1994-12-23 | 1995-02-22 | Orion Yhtymae Oy | A gelatine capsule |
| FR2753904B1 (fr) * | 1996-10-01 | 1998-10-30 | Gattefosse Ets Sa | Composition pharmaceutique a liberation modifiee de principe actif, comportant une matrice, et procede de fabrication |
| DE19743323C2 (de) * | 1997-09-30 | 2000-05-25 | Iip Inst Fuer Ind Pharmazie Fo | Feste Arzneimittelzusammensetzung auf der Grundlage von Selegilin |
| DE19814257A1 (de) | 1998-03-31 | 1999-10-07 | Asta Medica Ag | Brauseformulierungen |
| CA2346069C (en) * | 1998-10-07 | 2008-09-09 | Kyowa Hakko Kogyo Co., Ltd. | Tablet and tablet production method |
| US6635278B1 (en) | 1998-12-15 | 2003-10-21 | Gilead Sciences, Inc. | Pharmaceutical formulations |
| JP5258144B2 (ja) * | 2004-12-21 | 2013-08-07 | 株式会社分子生理化学研究所 | 吸収性の改善された固形状のコエンザイムｑ１０経口製剤の製造方法 |
| DE102012000786A1 (de) * | 2012-01-18 | 2013-07-18 | Stada Arzneimittel Ag | Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung, enthaltend den Wirkstoff Rasagilin |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3137125A (en) * | 1962-02-26 | 1964-06-16 | Kyryluk William Frederick | Solar motor |
| US4018543A (en) * | 1975-09-19 | 1977-04-19 | The Raymond Lee Organization, Inc. | Whirlwind power system |
| US4224528A (en) * | 1979-05-14 | 1980-09-23 | Argo William H | Solar thermal and wind energy power source |
| HU193662B (en) * | 1983-12-20 | 1987-11-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing synergetic pharmaceutical composition of antidepressive aktivity |
| DE3710966A1 (de) * | 1986-04-16 | 1987-12-03 | Degussa | Synergistische kombination von amantadin und selegilin |
| HU208484B (en) * | 1988-08-17 | 1993-11-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical composition containing acid additional salt of selegilin as active component for treating schisofrenia |
| US4935639A (en) * | 1988-08-23 | 1990-06-19 | Yeh Dong An | Revolving power tower |
| US5190763A (en) * | 1990-05-07 | 1993-03-02 | Alza Corporation | Dosage form indicated for the management of abnormal posture, tremor and involuntary movement |
| US5057321A (en) * | 1990-06-13 | 1991-10-15 | Alza Corporation | Dosage form comprising drug and maltodextrin |
| US5300817A (en) * | 1993-04-16 | 1994-04-05 | Baird William R | Solar venturi turbine |
-
1993
- 1993-04-02 SE SE19939301112A patent/SE9301112D0/xx unknown
-
1994
- 1994-03-31 EP EP96110727A patent/EP0739628A2/en not_active Withdrawn
- 1994-03-31 JP JP6521719A patent/JP2752792B2/ja not_active Expired - Fee Related
- 1994-03-31 CA CA002137164A patent/CA2137164C/en not_active Expired - Fee Related
- 1994-03-31 NZ NZ263568A patent/NZ263568A/en unknown
- 1994-03-31 ES ES94911961T patent/ES2083936T1/es active Pending
- 1994-03-31 DE DE0643578T patent/DE643578T1/de active Pending
- 1994-03-31 EP EP94911961A patent/EP0643578A1/en not_active Withdrawn
- 1994-03-31 WO PCT/FI1994/000128 patent/WO1994022435A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SE9301112D0 (sv) | 1993-04-02 |
| CA2137164A1 (en) | 1994-10-13 |
| WO1994022435A1 (en) | 1994-10-13 |
| JP2752792B2 (ja) | 1998-05-18 |
| AU663995B2 (en) | 1995-10-26 |
| CA2137164C (en) | 1997-04-08 |
| JPH07506845A (ja) | 1995-07-27 |
| ES2083936T1 (es) | 1996-05-01 |
| AU6430094A (en) | 1994-10-24 |
| EP0643578A1 (en) | 1995-03-22 |
| NZ263568A (en) | 1996-01-26 |
| EP0739628A2 (en) | 1996-10-30 |
| EP0739628A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1996-11-27 |
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