DE60337030D1 - Anti-idiotypische antikörper gegen faktor-viii-hemmer und deren verwendungen - Google Patents

Anti-idiotypische antikörper gegen faktor-viii-hemmer und deren verwendungen

Info

Publication number
DE60337030D1
DE60337030D1 DE60337030T DE60337030T DE60337030D1 DE 60337030 D1 DE60337030 D1 DE 60337030D1 DE 60337030 T DE60337030 T DE 60337030T DE 60337030 T DE60337030 T DE 60337030T DE 60337030 D1 DE60337030 D1 DE 60337030D1
Authority
DE
Germany
Prior art keywords
factor viii
idiotypic antibodies
antibodies
inhibitory
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60337030T
Other languages
English (en)
Inventor
Jean-Guy G Gilles
Jean-Marie R Saint-Remy
Marc G Jacquemin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Sciences Research Partners vzw
Original Assignee
Life Sciences Research Partners vzw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Sciences Research Partners vzw filed Critical Life Sciences Research Partners vzw
Application granted granted Critical
Publication of DE60337030D1 publication Critical patent/DE60337030D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE60337030T 2002-07-31 2003-07-28 Anti-idiotypische antikörper gegen faktor-viii-hemmer und deren verwendungen Expired - Lifetime DE60337030D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02447150A EP1388544A1 (de) 2002-07-31 2002-07-31 Anti-Idiotypische Antikörper gegen Factor VIII-Inhibitor und Verwendungen davon
PCT/EP2003/008365 WO2004014955A1 (en) 2002-07-31 2003-07-28 Anti-idiotypic antibodies against factor viii inhibitor and uses thereof

Publications (1)

Publication Number Publication Date
DE60337030D1 true DE60337030D1 (de) 2011-06-16

Family

ID=30129275

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60337030T Expired - Lifetime DE60337030D1 (de) 2002-07-31 2003-07-28 Anti-idiotypische antikörper gegen faktor-viii-hemmer und deren verwendungen

Country Status (11)

Country Link
US (1) US7582296B2 (de)
EP (2) EP1388544A1 (de)
JP (1) JP2006515565A (de)
AT (1) ATE508140T1 (de)
AU (1) AU2003260335B2 (de)
CA (1) CA2494698C (de)
DE (1) DE60337030D1 (de)
DK (1) DK1581560T3 (de)
ES (1) ES2366280T3 (de)
PT (1) PT1581560E (de)
WO (1) WO2004014955A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004010050A1 (de) * 2004-03-02 2005-09-22 Bayer Healthcare Ag Spezifische monoklonale und polyklonale Antikörper für Repinotan und dessen ringoffene Form
FR2889534B1 (fr) 2005-08-04 2012-11-02 Lab Francais Du Fractionnement Anticorps anti-idiotypique neutralisant l'activite inhibitrice d'un anticorps inhibiteur du facteur viii
FR2892724B1 (fr) * 2005-11-02 2008-01-04 Lab Francais Du Fractionnement Anticorps cytotoxiques diriges contre des anticorps inhibiteurs du facteur viii.
FR2897868B1 (fr) * 2006-02-24 2012-08-31 Lab Francais Du Fractionnement Anticorps anti-idiotypiques neutralisant l'activite inhibitrice d'un anticorps inhibiteur dirige contre le domaine c1 du facteur viii.
WO2009024653A1 (fr) * 2007-08-23 2009-02-26 Lfb Biotechnologies Anticorps anti-idiotypigues neutralisant l'activite inhibitrice d'un anticorps inhibiteur dirige contre le domaine c1 du facteur viii
GB201216002D0 (en) 2012-09-07 2012-10-24 Deutsches Rheuma Forschungszentrum Berlin Drfz Compositions adn methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639641A (en) * 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
US6210671B1 (en) * 1992-12-01 2001-04-03 Protein Design Labs, Inc. Humanized antibodies reactive with L-selectin
IT1277827B1 (it) * 1995-03-01 1997-11-12 Ministero Uni Ricerca Scient E Anticorpo monoclonale chimerico murino/umano o un suo frammento specifico per il recettore egf (egf-r)
DK0766745T3 (da) * 1995-04-08 2002-11-25 Lg Chemical Ltd Monoklonalt antistof, som er specifikt for humant 4-1BB samt cellelinje, som producerer dette
CA2205007C (en) * 1995-09-11 2010-12-14 Masamichi Koike Antibody against human interleukin-5 receptor .alpha. chain
JP3683278B2 (ja) * 1995-12-20 2005-08-17 ザ ユニバーシティ オブ ケンタッキー リサーチ ファウンデーション マウスモノクローナル抗イディオタイプ抗体11d10およびその使用方法
WO1999058680A2 (en) * 1998-05-08 1999-11-18 Stichting Sanquin Bloedvoorziening Method for diagnosis and treatment of haemophilia a patients with an inhibitor
EP1194528B1 (de) 1999-07-14 2007-03-07 D. Collen Research Foundation vzw Monoklonaler Antikörper der Faktor VIII selbst in molarem Überschuß nur teilweise inaktiviert und eine Methode zur Herstellung solch eines Antikörpers
EP1197755A1 (de) * 2000-10-11 2002-04-17 Pepscan Systems B.V. Bestimmung von Protein-Bindungsstellen

Also Published As

Publication number Publication date
AU2003260335A1 (en) 2004-02-25
DK1581560T3 (da) 2011-08-22
PT1581560E (pt) 2011-08-17
CA2494698A1 (en) 2004-02-19
CA2494698C (en) 2011-03-15
ATE508140T1 (de) 2011-05-15
ES2366280T3 (es) 2011-10-18
WO2004014955A9 (en) 2005-03-24
US7582296B2 (en) 2009-09-01
WO2004014955A1 (en) 2004-02-19
EP1581560B1 (de) 2011-05-04
US20060239998A1 (en) 2006-10-26
JP2006515565A (ja) 2006-06-01
AU2003260335B2 (en) 2009-01-08
EP1388544A1 (de) 2004-02-11
EP1581560A1 (de) 2005-10-05

Similar Documents

Publication Publication Date Title
ATE433973T1 (de) Azolylaminoazine als inhibitoren von proteinkinasen
NO20034056D0 (no) Proliferative sykdommer
DK1955700T3 (da) Terapeutisk behandling af androgenreceptor-betingede lidelser
ATE536188T1 (de) Fcgammariib-spezifische antikörper und verfahren zur verwendung davon
DE60222671D1 (de) Thienopyrimidinedione und deren verwendung in der behandlung von autoimmunerkrankungen
EA200901555A1 (ru) Композиция местного применения по уходу за кожей и способ лечения
CY1112055T1 (el) Συνθεσεις και μεθοδοι για την διαγνωση και θεραπευτικη αγωγη ογκου πνευμονα
DE60314603D1 (de) Zusammensetzungen brauchbar als protein-kinase- inhibitoren
EA200602062A1 (ru) Амидосоединения и их применение в качестве фармацевтических средств
DE60232660D1 (de) Humane dr4-antikörper und deren anwendungen
DE602004014117D1 (de) Thiazole zur verwendung als inhibitoren von protein-kinasen
DE60137307D1 (de) Substituierte sapogenine und ihre verwendung
ATE468336T1 (de) Azolylaminoazine als proteinkinasehemmer
MY147669A (en) Anti-alpha2 integrin antibodies and their uses
ATE508114T1 (de) Mit n-alkylhydroxamsäuren substituierte isoindolylverbindungen und deren pharmazeutische verwendung
DE602006017574D1 (de) Als protein-kinase-inhibitoren nutzbare benzimidazole
ATE534635T1 (de) N-pyrazinyl-phenylsulfonamide und deren verwendung zur behandlung von durch chemokine vermittelten krankheiten
DE60137337D1 (de) Vorbeugende und therapeutsche monoklonale antikörper gegen vacciniavirusantigene
EE200100179A (et) Farmatseutilised agendid Parkinsoni tõve, ADHD jamikroadenoomide raviks
ATE525480T1 (de) Verwendung von a33-antigenen und jam-it
ATE435020T1 (de) Oligo-beta-(1,3)-glucan und monoklonale antikörper gegen krebs
DE602004017326D1 (de) Tetrahydrocarbazolderivate und deren pharmazeutische verwendung
DE60337030D1 (de) Anti-idiotypische antikörper gegen faktor-viii-hemmer und deren verwendungen
ATE498010T1 (de) Natürliche igm-antikörper und inhibitoren davon
ATE317849T1 (de) 5-hydroxysapogenin derivate mit aktivität gegen demenz