DE60337030D1 - Anti-idiotypische antikörper gegen faktor-viii-hemmer und deren verwendungen - Google Patents

Anti-idiotypische antikörper gegen faktor-viii-hemmer und deren verwendungen

Info

Publication number
DE60337030D1
DE60337030D1 DE60337030T DE60337030T DE60337030D1 DE 60337030 D1 DE60337030 D1 DE 60337030D1 DE 60337030 T DE60337030 T DE 60337030T DE 60337030 T DE60337030 T DE 60337030T DE 60337030 D1 DE60337030 D1 DE 60337030D1
Authority
DE
Germany
Prior art keywords
factor viii
idiotypic antibodies
antibodies
inhibitory
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60337030T
Other languages
English (en)
Inventor
Jean-Guy G Gilles
Jean-Marie R Saint-Remy
Marc G Jacquemin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Sciences Research Partners vzw
Original Assignee
Life Sciences Research Partners vzw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Sciences Research Partners vzw filed Critical Life Sciences Research Partners vzw
Application granted granted Critical
Publication of DE60337030D1 publication Critical patent/DE60337030D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE60337030T 2002-07-31 2003-07-28 Anti-idiotypische antikörper gegen faktor-viii-hemmer und deren verwendungen Expired - Lifetime DE60337030D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02447150A EP1388544A1 (de) 2002-07-31 2002-07-31 Anti-Idiotypische Antikörper gegen Factor VIII-Inhibitor und Verwendungen davon
PCT/EP2003/008365 WO2004014955A1 (en) 2002-07-31 2003-07-28 Anti-idiotypic antibodies against factor viii inhibitor and uses thereof

Publications (1)

Publication Number Publication Date
DE60337030D1 true DE60337030D1 (de) 2011-06-16

Family

ID=30129275

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60337030T Expired - Lifetime DE60337030D1 (de) 2002-07-31 2003-07-28 Anti-idiotypische antikörper gegen faktor-viii-hemmer und deren verwendungen

Country Status (11)

Country Link
US (1) US7582296B2 (de)
EP (2) EP1388544A1 (de)
JP (1) JP2006515565A (de)
AT (1) ATE508140T1 (de)
AU (1) AU2003260335B2 (de)
CA (1) CA2494698C (de)
DE (1) DE60337030D1 (de)
DK (1) DK1581560T3 (de)
ES (1) ES2366280T3 (de)
PT (1) PT1581560E (de)
WO (1) WO2004014955A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004010050A1 (de) * 2004-03-02 2005-09-22 Bayer Healthcare Ag Spezifische monoklonale und polyklonale Antikörper für Repinotan und dessen ringoffene Form
FR2889534B1 (fr) * 2005-08-04 2012-11-02 Lab Francais Du Fractionnement Anticorps anti-idiotypique neutralisant l'activite inhibitrice d'un anticorps inhibiteur du facteur viii
FR2892724B1 (fr) * 2005-11-02 2008-01-04 Lab Francais Du Fractionnement Anticorps cytotoxiques diriges contre des anticorps inhibiteurs du facteur viii.
FR2897868B1 (fr) * 2006-02-24 2012-08-31 Lab Francais Du Fractionnement Anticorps anti-idiotypiques neutralisant l'activite inhibitrice d'un anticorps inhibiteur dirige contre le domaine c1 du facteur viii.
CN101883793A (zh) * 2007-08-23 2010-11-10 Lfb生物科技公司 中和针对因子ⅷ的c1结构域的抑制性抗体的抑制活性的抗独特型抗体
GB201216002D0 (en) * 2012-09-07 2012-10-24 Deutsches Rheuma Forschungszentrum Berlin Drfz Compositions adn methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639641A (en) * 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
US6210671B1 (en) * 1992-12-01 2001-04-03 Protein Design Labs, Inc. Humanized antibodies reactive with L-selectin
IT1277827B1 (it) * 1995-03-01 1997-11-12 Ministero Uni Ricerca Scient E Anticorpo monoclonale chimerico murino/umano o un suo frammento specifico per il recettore egf (egf-r)
DE69624436T2 (de) * 1995-04-08 2003-08-28 Lg Chemical Ltd Humaner 4-1bb spezifischer humaner antikörper und diesen produzierende zellinie
AU690474B2 (en) * 1995-09-11 1998-04-23 Kyowa Hakko Kirin Co., Ltd. Antibody againts alpha-chain of human interleukin 5 receptor
JP3683278B2 (ja) * 1995-12-20 2005-08-17 ザ ユニバーシティ オブ ケンタッキー リサーチ ファウンデーション マウスモノクローナル抗イディオタイプ抗体11d10およびその使用方法
WO1999058680A2 (en) * 1998-05-08 1999-11-18 Stichting Sanquin Bloedvoorziening Method for diagnosis and treatment of haemophilia a patients with an inhibitor
DK1194528T3 (da) 1999-07-14 2007-07-09 D Collen Res Foundation Vzw Monoklonalt antistof mod faktor VII, hvilket antistof selv ved forekomst i molært overskud kun delvist inaktiverer faktor VII, samt fremgangsmåde til produktion af et sådant antistof
EP1197755A1 (de) * 2000-10-11 2002-04-17 Pepscan Systems B.V. Bestimmung von Protein-Bindungsstellen

Also Published As

Publication number Publication date
CA2494698A1 (en) 2004-02-19
ATE508140T1 (de) 2011-05-15
ES2366280T3 (es) 2011-10-18
CA2494698C (en) 2011-03-15
WO2004014955A1 (en) 2004-02-19
EP1388544A1 (de) 2004-02-11
DK1581560T3 (da) 2011-08-22
US7582296B2 (en) 2009-09-01
AU2003260335B2 (en) 2009-01-08
PT1581560E (pt) 2011-08-17
AU2003260335A1 (en) 2004-02-25
JP2006515565A (ja) 2006-06-01
WO2004014955A9 (en) 2005-03-24
US20060239998A1 (en) 2006-10-26
EP1581560B1 (de) 2011-05-04
EP1581560A1 (de) 2005-10-05

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