DE60326781D1 - Lichtaktivierte Gentransduktion unter Verwendung von ultraviolettem Licht zur zellengerichteten Zuführung von Genen - Google Patents
Lichtaktivierte Gentransduktion unter Verwendung von ultraviolettem Licht zur zellengerichteten Zuführung von GenenInfo
- Publication number
- DE60326781D1 DE60326781D1 DE60326781T DE60326781T DE60326781D1 DE 60326781 D1 DE60326781 D1 DE 60326781D1 DE 60326781 T DE60326781 T DE 60326781T DE 60326781 T DE60326781 T DE 60326781T DE 60326781 D1 DE60326781 D1 DE 60326781D1
- Authority
- DE
- Germany
- Prior art keywords
- cell
- light
- ultraviolet light
- vector
- genes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0083—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the administration regime
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35390702P | 2002-01-31 | 2002-01-31 | |
US35384202P | 2002-01-31 | 2002-01-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60326781D1 true DE60326781D1 (de) | 2009-04-30 |
Family
ID=27669127
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60310525T Expired - Lifetime DE60310525T2 (de) | 2002-01-31 | 2003-01-31 | Ultraviolette licht zur lichtaktivierten gentransduktion bei der genzuführung |
DE60326781T Expired - Lifetime DE60326781D1 (de) | 2002-01-31 | 2003-01-31 | Lichtaktivierte Gentransduktion unter Verwendung von ultraviolettem Licht zur zellengerichteten Zuführung von Genen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60310525T Expired - Lifetime DE60310525T2 (de) | 2002-01-31 | 2003-01-31 | Ultraviolette licht zur lichtaktivierten gentransduktion bei der genzuführung |
Country Status (7)
Country | Link |
---|---|
US (2) | US7524327B2 (de) |
EP (3) | EP1472348B1 (de) |
AT (2) | ATE348884T1 (de) |
AU (1) | AU2003210820B2 (de) |
CA (1) | CA2474485A1 (de) |
DE (2) | DE60310525T2 (de) |
WO (1) | WO2003064680A2 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE348884T1 (de) * | 2002-01-31 | 2007-01-15 | Univ Rochester | Ultraviolette licht zur lichtaktivierten gentransduktion bei der genzuführung |
US7704272B2 (en) * | 2002-01-31 | 2010-04-27 | University Of Rochester | Method for introducing an ultraviolet light activated viral vector into the spinal column |
CA2514643A1 (en) * | 2003-01-31 | 2004-08-19 | University Of Rochester | Light probe for ultraviolet light activated gene transduction |
WO2006024038A2 (en) * | 2004-08-27 | 2006-03-02 | Codman & Shurtleff | Light-based implant for treating alzheimer’s disease |
US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
US7288108B2 (en) | 2005-03-14 | 2007-10-30 | Codman & Shurtleff, Inc. | Red light implant for treating Parkinson's disease |
USRE47266E1 (en) * | 2005-03-14 | 2019-03-05 | DePuy Synthes Products, Inc. | Light-based implants for treating Alzheimer's disease |
US8463439B2 (en) | 2009-03-31 | 2013-06-11 | Intuitive Surgical Operations, Inc. | Optic fiber connection for a force sensing instrument |
US7351253B2 (en) | 2005-06-16 | 2008-04-01 | Codman & Shurtleff, Inc. | Intranasal red light probe for treating Alzheimer's disease |
US8167920B2 (en) * | 2005-10-31 | 2012-05-01 | Codman & Shurtleff, Inc. | Intranasal delivery of compounds that reduce intrancranial pressure |
JP4761224B2 (ja) * | 2006-10-12 | 2011-08-31 | 富士電機デバイステクノロジー株式会社 | 垂直磁気記録媒体 |
US9320914B2 (en) | 2008-03-03 | 2016-04-26 | DePuy Synthes Products, Inc. | Endoscopic delivery of red/NIR light to the subventricular zone |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT395321B (de) * | 1983-07-05 | 1992-11-25 | Ebner Ind Ofenbau | Verfahren zum abkuehlen von chargen in diskontinuierlich arbeitenden industrieoefen, insbesondere von stahldraht- oder - bandbunden in haubengluehoefen |
CA1245726A (en) | 1984-01-19 | 1988-11-29 | Francis A. L'esperance | Laser incisional device |
US4671273A (en) | 1984-03-19 | 1987-06-09 | Lindsey Ernest J | Laser hand piece, for use in opthalmic, plastic, and ear, nose, and throat surgery |
DE3415293A1 (de) | 1984-04-24 | 1985-11-14 | Osada Electric Co. Ltd., Tokio/Tokyo | Laser-handgeraet |
US5188632A (en) * | 1984-12-07 | 1993-02-23 | Advanced Interventional Systems, Inc. | Guidance and delivery system for high-energy pulsed laser light |
US4846172A (en) * | 1987-05-26 | 1989-07-11 | Berlin Michael S | Laser-delivery eye-treatment method |
WO1989003202A2 (en) | 1987-10-14 | 1989-04-20 | Schneider Richard T | Method and apparatus for laser emulsification |
US5084043A (en) * | 1990-01-12 | 1992-01-28 | Laserscope | Method for performing a percutaneous diskectomy using a laser |
US5242439A (en) * | 1990-01-12 | 1993-09-07 | Laserscope | Means for inserting instrumentation for a percutaneous diskectomy using a laser |
US5201729A (en) * | 1990-01-12 | 1993-04-13 | Laserscope | Method for performing percutaneous diskectomy using a laser |
DE4219626A1 (de) | 1992-06-16 | 1993-12-23 | Wehling Peter Priv Doz Dr Med | Methode zur Einschleusung therapeutisch relevanter Gene in Körperzellen |
US5340734A (en) * | 1992-11-25 | 1994-08-23 | Biosource Genetics Corporation | Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom |
AU692434B2 (en) | 1993-01-21 | 1998-06-11 | President And Fellows Of Harvard College | Methods and diagnostic kits utilizing mammalian stress promoters to determine toxicity of a compound |
DE9317847U1 (de) | 1993-10-29 | 1994-01-20 | Witwity Taufik Dr | Kanüle |
US5604090A (en) * | 1994-06-06 | 1997-02-18 | Fred Hutchinson Cancer Research Center | Method for increasing transduction of cells by adeno-associated virus vectors |
IL115851A0 (en) * | 1995-11-02 | 1996-01-31 | Riklis Emanual | Cosmetic compositions |
US5883740A (en) * | 1995-12-14 | 1999-03-16 | Chubb; Charles R. | Skin light exposure control methods |
US5843459A (en) * | 1996-01-19 | 1998-12-01 | Human Gene Therapy Research Institute | Differential inactivation of nucleic acids by chemical modification |
US6300127B1 (en) * | 1997-07-30 | 2001-10-09 | Emory University | Bone mineralization proteins, DNA, vectors, expression systems |
DE29716011U1 (de) * | 1997-09-06 | 1997-10-30 | Reitenbach Paul | Gerät zur ultravioletten intravenösen Bestrahlung des Eigenblutes mit fieberoptischer Lichtsonde |
WO1999047177A1 (en) | 1998-03-18 | 1999-09-23 | The University Of Virginia Patent Foundation | Gene therapy vector with osteocalcin promoter and genes for bone morphogenic proteins or growth factors |
US6593084B2 (en) * | 1998-10-13 | 2003-07-15 | Robert E. Bird | Carcinogen assay |
US6254547B1 (en) * | 1999-11-08 | 2001-07-03 | Michael Phillips | Breath methylated alkane contour: a new marker of oxidative stress and disease |
AUPQ306999A0 (en) * | 1999-09-24 | 1999-10-21 | Canon Kabushiki Kaisha | Intercom system |
EP1130086A1 (de) * | 2000-02-18 | 2001-09-05 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Genetische manipulierte Keratinozyten und deren Verwendung zur Prüfung der Toxizität |
AU2002241628A1 (en) * | 2000-12-15 | 2002-06-24 | Mitokor | Cobalt-porphyrin complexes and use thereof as an anti-obesity agent |
US20030023284A1 (en) * | 2001-02-20 | 2003-01-30 | Vladimir Gartstein | Method and apparatus for the in-vivo treatment of pathogens |
ES2276728T3 (es) * | 2001-02-23 | 2007-07-01 | Chemisches Laboratorium Dr. Kurt Richter Gmbh | Composicion de uso topico. |
US7704272B2 (en) * | 2002-01-31 | 2010-04-27 | University Of Rochester | Method for introducing an ultraviolet light activated viral vector into the spinal column |
ATE348884T1 (de) * | 2002-01-31 | 2007-01-15 | Univ Rochester | Ultraviolette licht zur lichtaktivierten gentransduktion bei der genzuführung |
CA2514643A1 (en) * | 2003-01-31 | 2004-08-19 | University Of Rochester | Light probe for ultraviolet light activated gene transduction |
-
2003
- 2003-01-31 AT AT03735128T patent/ATE348884T1/de not_active IP Right Cessation
- 2003-01-31 EP EP03735128A patent/EP1472348B1/de not_active Expired - Lifetime
- 2003-01-31 US US10/357,271 patent/US7524327B2/en not_active Expired - Fee Related
- 2003-01-31 WO PCT/US2003/003174 patent/WO2003064680A2/en active IP Right Grant
- 2003-01-31 CA CA002474485A patent/CA2474485A1/en not_active Abandoned
- 2003-01-31 EP EP08101769A patent/EP1939285A1/de not_active Withdrawn
- 2003-01-31 EP EP06124972A patent/EP1867715B1/de not_active Expired - Lifetime
- 2003-01-31 DE DE60310525T patent/DE60310525T2/de not_active Expired - Lifetime
- 2003-01-31 DE DE60326781T patent/DE60326781D1/de not_active Expired - Lifetime
- 2003-01-31 AU AU2003210820A patent/AU2003210820B2/en not_active Ceased
- 2003-01-31 AT AT06124972T patent/ATE426020T1/de not_active IP Right Cessation
-
2008
- 2008-09-02 US US12/203,056 patent/US20090093867A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60310525T2 (de) | 2007-10-04 |
US7524327B2 (en) | 2009-04-28 |
EP1472348A4 (de) | 2005-04-13 |
WO2003064680A2 (en) | 2003-08-07 |
AU2003210820B2 (en) | 2007-12-20 |
EP1472348B1 (de) | 2006-12-20 |
EP1867715B1 (de) | 2009-03-18 |
US20030236394A1 (en) | 2003-12-25 |
EP1939285A1 (de) | 2008-07-02 |
CA2474485A1 (en) | 2003-08-07 |
EP1472348A2 (de) | 2004-11-03 |
US20090093867A1 (en) | 2009-04-09 |
ATE426020T1 (de) | 2009-04-15 |
EP1867715A1 (de) | 2007-12-19 |
ATE348884T1 (de) | 2007-01-15 |
WO2003064680A3 (en) | 2004-07-22 |
DE60310525D1 (de) | 2007-02-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |