DE60313357D1 - Verfahren zur katalytischen hydrierung von kohlenstoff-heteroatom-doppelbindungen - Google Patents
Verfahren zur katalytischen hydrierung von kohlenstoff-heteroatom-doppelbindungenInfo
- Publication number
- DE60313357D1 DE60313357D1 DE60313357T DE60313357T DE60313357D1 DE 60313357 D1 DE60313357 D1 DE 60313357D1 DE 60313357 T DE60313357 T DE 60313357T DE 60313357 T DE60313357 T DE 60313357T DE 60313357 D1 DE60313357 D1 DE 60313357D1
- Authority
- DE
- Germany
- Prior art keywords
- catalytic hydrogenation
- heteroatom double
- carbon heteroatom
- double bindings
- carbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 title 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 title 1
- 239000003054 catalyst Substances 0.000 abstract 2
- 238000005984 hydrogenation reaction Methods 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 abstract 1
- 239000012327 Ruthenium complex Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B41/00—Formation or introduction of functional groups containing oxygen
- C07B41/02—Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B43/00—Formation or introduction of functional groups containing nitrogen
- C07B43/04—Formation or introduction of functional groups containing nitrogen of amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH20332002 | 2002-12-02 | ||
| CH203302 | 2002-12-02 | ||
| PCT/EP2003/050902 WO2004050585A1 (en) | 2002-12-02 | 2003-11-27 | Catalytic hydrogeneration of carbon-heteroatom double bonds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60313357D1 true DE60313357D1 (de) | 2007-05-31 |
| DE60313357T2 DE60313357T2 (de) | 2008-01-03 |
Family
ID=32399972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60313357T Expired - Lifetime DE60313357T2 (de) | 2002-12-02 | 2003-11-27 | Verfahren zur katalytischen hydrierung von kohlenstoff-heteroatom-doppelbindungen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7446236B2 (de) |
| EP (1) | EP1567464B1 (de) |
| JP (1) | JP2006508161A (de) |
| CN (1) | CN100384791C (de) |
| AT (1) | ATE359986T1 (de) |
| AU (1) | AU2003298328A1 (de) |
| CA (1) | CA2507908A1 (de) |
| DE (1) | DE60313357T2 (de) |
| ES (1) | ES2283867T3 (de) |
| WO (1) | WO2004050585A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7326784B2 (en) | 2003-12-19 | 2008-02-05 | Altana Pharma Ag | Intermediates for the preparation of tricyclic dihydropyrano-imidazo-pyridines derivatives |
| EP2343304B1 (de) | 2005-02-16 | 2015-06-10 | Anacor Pharmaceuticals, Inc. | Biozide Boronophthalidverbindungen |
| WO2007078340A2 (en) | 2005-12-30 | 2007-07-12 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| EP1988779B1 (de) | 2006-02-16 | 2015-06-24 | Anacor Pharmaceuticals, Inc. | Kleine boronhaltige moleküle als entzündungshemmende wirkstoffe |
| CA2645107A1 (en) * | 2006-03-10 | 2007-09-20 | Solvias Ag | Asymmetric catalytic hydrogenation of prochiral ketones and aldehydes |
| BRPI0908565A2 (pt) | 2008-03-06 | 2017-05-23 | Anacor Pharmaceuticals Inc | composto, formulação farmacêutica, métodos para reduzir a liberação de uma citocina ou de uma quimiocina, para tratar uma condição em um animal e para inibir uma fosfodiesterase |
| EP2348863A4 (de) | 2008-09-04 | 2012-03-07 | Anacor Pharmaceuticals Inc | Borhaltige kleine moleküle |
| US8461336B2 (en) * | 2008-09-04 | 2013-06-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| JP5721695B2 (ja) | 2009-03-17 | 2015-05-20 | ジョンソン、マッセイ、パブリック、リミテッド、カンパニーＪｏｈｎｓｏｎ Ｍａｔｔｈｅｙ Ｐｕｂｌｉｃｌｉｍｉｔｅｄ Ｃｏｍｐａｎｙ | Ｒｕ（ｉｉ）触媒の存在下でケトンを水素化する方法 |
| WO2011019618A1 (en) * | 2009-08-14 | 2011-02-17 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
| US9346834B2 (en) | 2009-10-20 | 2016-05-24 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
| US8461134B2 (en) * | 2009-11-11 | 2013-06-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| WO2011094450A1 (en) | 2010-01-27 | 2011-08-04 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules |
| AP2012006482A0 (en) | 2010-03-19 | 2012-10-31 | Anacor Pharmacueticals Inc | Boron-containing small molecules as anti-protozoalagent |
| CN102821609B (zh) * | 2010-04-07 | 2015-03-25 | 葛兰素史密丝克莱恩有限责任公司 | 用于制备苯并氧杂硼杂环戊烯的方法 |
| MX338209B (es) | 2010-09-07 | 2016-04-07 | Anacor Pharmaceuticals Inc | Derivados de benzoxaborol para tratar infecciones bacterianas. |
| CN105492388B (zh) | 2013-08-09 | 2018-12-21 | 葛兰素史克知识产权第二有限公司 | 三环苯并氧杂硼杂环戊烯化合物及其用途 |
| GB201401230D0 (en) * | 2014-01-24 | 2014-03-12 | Givaudan Sa | Improvements in or relating to organic compounds |
| MA41494B1 (fr) | 2015-02-12 | 2020-10-28 | Glaxosmithkline Ip No 2 Ltd | Composés benzoxaborole substitués en position 4 et utilisations associées |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2693190B1 (fr) * | 1992-07-02 | 1994-09-23 | Elf Aquitaine | Procédé d'hydrogénation énantiosélectif de la double liaison C=O OXO. |
| US6476233B1 (en) * | 1998-11-12 | 2002-11-05 | The Penn State Research Foundation | Transition metal-catalyzed reactions based on chiral amine oxazolinyl ligands and related compounds |
| NL1015655C2 (nl) * | 2000-07-07 | 2002-01-08 | Dsm Nv | Katalysator voor de asymmetrische hydrogenering. |
| WO2002022526A2 (en) * | 2000-09-13 | 2002-03-21 | Firmenich S.A. | Catalytic hydrogenation processes |
-
2003
- 2003-11-27 CN CNB2003801045565A patent/CN100384791C/zh not_active Expired - Lifetime
- 2003-11-27 ES ES03796062T patent/ES2283867T3/es not_active Expired - Lifetime
- 2003-11-27 DE DE60313357T patent/DE60313357T2/de not_active Expired - Lifetime
- 2003-11-27 US US10/536,883 patent/US7446236B2/en active Active
- 2003-11-27 JP JP2004556337A patent/JP2006508161A/ja active Pending
- 2003-11-27 WO PCT/EP2003/050902 patent/WO2004050585A1/en active IP Right Grant
- 2003-11-27 CA CA002507908A patent/CA2507908A1/en not_active Abandoned
- 2003-11-27 AU AU2003298328A patent/AU2003298328A1/en not_active Abandoned
- 2003-11-27 EP EP03796062A patent/EP1567464B1/de not_active Expired - Lifetime
- 2003-11-27 AT AT03796062T patent/ATE359986T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60313357T2 (de) | 2008-01-03 |
| US7446236B2 (en) | 2008-11-04 |
| EP1567464B1 (de) | 2007-04-18 |
| CN1717376A (zh) | 2006-01-04 |
| ES2283867T3 (es) | 2007-11-01 |
| JP2006508161A (ja) | 2006-03-09 |
| AU2003298328A1 (en) | 2004-06-23 |
| CN100384791C (zh) | 2008-04-30 |
| CA2507908A1 (en) | 2004-06-17 |
| WO2004050585A1 (en) | 2004-06-17 |
| US20060106247A1 (en) | 2006-05-18 |
| EP1567464A1 (de) | 2005-08-31 |
| ATE359986T1 (de) | 2007-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |