DE60312220D1 - Vorrichtung zum abgeben einer probe in elektrospray-massenspektrometern - Google Patents
Vorrichtung zum abgeben einer probe in elektrospray-massenspektrometernInfo
- Publication number
- DE60312220D1 DE60312220D1 DE60312220T DE60312220T DE60312220D1 DE 60312220 D1 DE60312220 D1 DE 60312220D1 DE 60312220 T DE60312220 T DE 60312220T DE 60312220 T DE60312220 T DE 60312220T DE 60312220 D1 DE60312220 D1 DE 60312220D1
- Authority
- DE
- Germany
- Prior art keywords
- giving
- sample
- mass spectrometers
- electrospray mass
- electrospray
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0013—Miniaturised spectrometers, e.g. having smaller than usual scale, integrated conventional components
- H01J49/0018—Microminiaturised spectrometers, e.g. chip-integrated devices, Micro-Electro-Mechanical Systems [MEMS]
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
- H01J49/165—Electrospray ionisation
- H01J49/167—Capillaries and nozzles specially adapted therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0226160.0A GB0226160D0 (en) | 2002-11-08 | 2002-11-08 | Apparatus for dispensing a sample in electrospray mass spectrometers |
GB0226160 | 2002-11-08 | ||
PCT/EP2003/013328 WO2004051697A2 (en) | 2002-11-08 | 2003-11-07 | Apparatus for dispensing a sample in electrospray mass spectrometers |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60312220D1 true DE60312220D1 (de) | 2007-04-12 |
DE60312220T2 DE60312220T2 (de) | 2007-11-15 |
Family
ID=9947512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60312220T Expired - Fee Related DE60312220T2 (de) | 2002-11-08 | 2003-11-07 | Vorrichtung zum abgeben einer probe in elektrospray-massenspektrometern |
Country Status (7)
Country | Link |
---|---|
US (1) | US7265348B2 (de) |
EP (1) | EP1576642B1 (de) |
JP (1) | JP2006505797A (de) |
AU (1) | AU2003302509A1 (de) |
DE (1) | DE60312220T2 (de) |
GB (1) | GB0226160D0 (de) |
WO (1) | WO2004051697A2 (de) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0226160D0 (en) * | 2002-11-08 | 2002-12-18 | Diagnoswiss Sa | Apparatus for dispensing a sample in electrospray mass spectrometers |
SE0300454D0 (sv) * | 2003-02-19 | 2003-02-19 | Aamic Ab | Nozzles for electrospray ionization and methods of fabricating them |
US7007710B2 (en) * | 2003-04-21 | 2006-03-07 | Predicant Biosciences, Inc. | Microfluidic devices and methods |
AU2004272746B2 (en) * | 2003-09-15 | 2009-12-03 | Diagnoswiss S.A. | Microfluidic flow monitoring device |
US7537807B2 (en) | 2003-09-26 | 2009-05-26 | Cornell University | Scanned source oriented nanofiber formation |
EP1817576A1 (de) * | 2004-11-12 | 2007-08-15 | DiagnoSwiss S.A. | Mikrofluidvorrichtung mit minimiertem ohmschen widerstand |
CA2621910A1 (en) * | 2005-09-07 | 2007-03-15 | Human Metabolome Technologies, Inc. | Method for calibrating detected mass in mass spectrometry system |
GB0607205D0 (en) * | 2006-04-10 | 2006-05-17 | Diagnoswiss Sa | Miniaturised biosensor with optimized anperimetric detection |
US7495210B2 (en) | 2006-05-04 | 2009-02-24 | Agilent Technologies, Inc. | Micro fluidic gas assisted ionization device and method |
GB0712795D0 (en) * | 2007-07-02 | 2007-08-08 | Ecole Polytechnique Federale De | Solid phase extraction and ionization device |
US7928368B2 (en) * | 2007-11-02 | 2011-04-19 | Licentia Oy | Micropillar array electrospray chip |
US8242441B2 (en) * | 2009-12-18 | 2012-08-14 | Thermo Finnigan Llc | Apparatus and methods for pneumatically-assisted electrospray emitter array |
US8207496B2 (en) | 2010-02-05 | 2012-06-26 | Thermo Finnigan Llc | Multi-needle multi-parallel nanospray ionization source for mass spectrometry |
US8309916B2 (en) | 2010-08-18 | 2012-11-13 | Thermo Finnigan Llc | Ion transfer tube having single or multiple elongate bore segments and mass spectrometer system |
US8847154B2 (en) | 2010-08-18 | 2014-09-30 | Thermo Finnigan Llc | Ion transfer tube for a mass spectrometer system |
WO2013003795A1 (en) * | 2011-06-29 | 2013-01-03 | The Regents Of The University Of California | Multinozzle emitter arrays for ultrahigh-throughput nanoelectrospray mass spectrometry |
US9087683B2 (en) | 2012-01-06 | 2015-07-21 | Ecole Polytechnique Federale De Lausanne | Electrostatic spray ionization method |
US9903845B2 (en) * | 2012-02-13 | 2018-02-27 | Waters Technologies Corporation | Ionization of analyte molecules comprised in a flow of gas |
US9058966B2 (en) * | 2012-09-07 | 2015-06-16 | Canon Kabushiki Kaisha | Ionization device, mass spectrometer including ionization device, image display system including mass spectrometer, and analysis method |
EP3042190B1 (de) * | 2013-08-29 | 2024-04-03 | University of Notre Dame du Lac | Hochempfindliche elektrospray-schnittstelle |
US10933636B2 (en) * | 2013-12-06 | 2021-03-02 | Palo Alto Research Center Incorporated | Print head design for ballistic aerosol marking with smooth particulate injection from an array of inlets into a matching array of microchannels |
JP6667248B2 (ja) * | 2014-10-14 | 2020-03-18 | ウオーターズ・テクノロジーズ・コーポレイシヨン | ポストカラム調節剤およびマイクロ流体デバイスを使用したエレクトロスプレーイオン化質量分析における検出の感度強化 |
RU2608366C2 (ru) * | 2014-12-05 | 2017-01-18 | Общество с ограниченной ответственностью "Альфа" (ООО "Альфа") | Способ стабильного электрораспыления растворов в источнике ионов при атмосферном давлении |
CN107530065A (zh) | 2015-03-06 | 2018-01-02 | 英国质谱公司 | 活体内内窥镜下组织识别工具 |
EP3265821B1 (de) * | 2015-03-06 | 2021-06-16 | Micromass UK Limited | Flüssigkeitsfalle oder separator für elektrochirurgische anwendungen |
GB2554180B (en) | 2015-03-06 | 2022-04-13 | Micromass Ltd | Spectrometric analysis |
CN107548516B (zh) | 2015-03-06 | 2019-11-15 | 英国质谱公司 | 用于改进电离的碰撞表面 |
CN110057901B (zh) | 2015-03-06 | 2022-07-01 | 英国质谱公司 | 拭子和活检样品的快速蒸发电离质谱和解吸电喷雾电离质谱分析 |
GB2553937B (en) | 2015-03-06 | 2022-06-08 | Micromass Ltd | Improved ionisation of gaseous samples |
EP3741303A3 (de) | 2015-03-06 | 2020-12-30 | Micromass UK Limited | Chemisch geführte umgebungsionisationsmassenspektrometrie |
GB2554202B (en) | 2015-03-06 | 2021-08-18 | Micromass Ltd | Imaging guided ambient ionisation mass spectrometry |
CA2978042A1 (en) | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | Tissue analysis by mass spectrometry or ion mobility spectrometry |
WO2016142681A1 (en) | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | Spectrometric analysis of microbes |
WO2016142669A1 (en) | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | Physically guided rapid evaporative ionisation mass spectrometry ("reims") |
CN112964625B (zh) | 2015-03-06 | 2024-06-07 | 英国质谱公司 | 细胞群体分析 |
US10777397B2 (en) | 2015-03-06 | 2020-09-15 | Micromass Uk Limited | Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry (“REIMS”) device |
CN107533032A (zh) | 2015-03-06 | 2018-01-02 | 英国质谱公司 | 用于从块状组织直接映射的原位电离质谱测定成像平台 |
GB201517195D0 (en) | 2015-09-29 | 2015-11-11 | Micromass Ltd | Capacitively coupled reims technique and optically transparent counter electrode |
US10329079B2 (en) * | 2015-10-06 | 2019-06-25 | Hamilton Sundstrand Corporation | Aerosol/solvent delivery nozzles |
WO2017095813A1 (en) | 2015-11-30 | 2017-06-08 | Intabio, Inc. | Devices and methods for sample characterization |
WO2017178833A1 (en) | 2016-04-14 | 2017-10-19 | Micromass Uk Limited | Spectrometric analysis of plants |
KR102691269B1 (ko) * | 2018-01-29 | 2024-08-05 | 인타바이오 엘엘씨 | 샘플 특성화를 위한 장치, 방법 및 키트 |
WO2019200166A1 (en) * | 2018-04-11 | 2019-10-17 | The Trustees Of Indiana University | Cartridges, systems and methods for mass spectrometry |
GB201807914D0 (en) * | 2018-05-16 | 2018-06-27 | Micromass Ltd | Impactor spray or electrospray ionisation ion source |
CN112534549A (zh) | 2018-05-31 | 2021-03-19 | 因塔生物公司 | 用于微流体系统与质谱联用的软件 |
US11285484B2 (en) | 2019-08-12 | 2022-03-29 | Intabio, Llc | Multichannel isoelectric focusing devices and high voltage power supplies |
CN111889155A (zh) * | 2020-08-25 | 2020-11-06 | 苏州福鲁特分精密仪器有限公司 | 一种多通道电喷雾微流控芯片及其应用 |
CN113083386B (zh) * | 2021-04-02 | 2023-04-18 | 重庆大学 | 一种液样简便、快速离散化芯片及其使用方法 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE34757E (en) * | 1988-04-05 | 1994-10-18 | Battelle Memorial Institute | Combined electrophoresis-electrospray interface and method |
WO1992021138A1 (en) * | 1991-05-21 | 1992-11-26 | Analytica Of Brandford, Inc. | Method and apparatus for improving electrospray ionization of solute species |
US5872010A (en) * | 1995-07-21 | 1999-02-16 | Northeastern University | Microscale fluid handling system |
US5873523A (en) * | 1996-02-29 | 1999-02-23 | Yale University | Electrospray employing corona-assisted cone-jet mode |
JPH112622A (ja) | 1997-06-13 | 1999-01-06 | Hitachi Ltd | 質量分析装置 |
US6274867B1 (en) * | 1998-09-28 | 2001-08-14 | Varian, Inc. | Multiple liquid flow electrospray interface |
EP1166340A4 (de) | 1998-11-19 | 2009-04-22 | California Inst Of Techn | Polymerbasierte elektrosprühdüse für die massenspektroskopie |
GB9907249D0 (en) | 1999-03-29 | 1999-05-26 | Cole Polytechnique Fudurale De | Chemical assay apparatus |
GB0010957D0 (en) * | 2000-05-05 | 2000-06-28 | Novartis Ag | Compound & method |
US6918309B2 (en) * | 2001-01-17 | 2005-07-19 | Irm Llc | Sample deposition method and system |
GB0103516D0 (en) * | 2001-02-13 | 2001-03-28 | Cole Polytechnique Federale De | Apparatus for dispensing a sample |
US7037417B2 (en) * | 2001-03-19 | 2006-05-02 | Ecole Polytechnique Federale De Lausanne | Mechanical control of fluids in micro-analytical devices |
US6610978B2 (en) * | 2001-03-27 | 2003-08-26 | Agilent Technologies, Inc. | Integrated sample preparation, separation and introduction microdevice for inductively coupled plasma mass spectrometry |
KR100368930B1 (ko) * | 2001-03-29 | 2003-01-24 | 한국과학기술원 | 반도체 기판 위에 높이 떠 있는 3차원 금속 소자, 그 회로모델, 및 그 제조방법 |
GB0111438D0 (en) * | 2001-05-10 | 2001-07-04 | Cole Polytechnique Federale De | Polymer bonding by means of plasma activation |
GB0116384D0 (en) * | 2001-07-04 | 2001-08-29 | Diagnoswiss Sa | Microfluidic chemical assay apparatus and method |
US6766817B2 (en) * | 2001-07-25 | 2004-07-27 | Tubarc Technologies, Llc | Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action |
GB0121189D0 (en) * | 2001-08-31 | 2001-10-24 | Diagnoswiss Sa | Apparatus and method for separating an analyte |
US6803568B2 (en) * | 2001-09-19 | 2004-10-12 | Predicant Biosciences, Inc. | Multi-channel microfluidic chip for electrospray ionization |
DE10213390C1 (de) * | 2002-03-26 | 2003-08-14 | Bruker Daltonik Gmbh | Kopplung Kapillarelektrophorese (CE) mit Massenspektrometrie (MS) unter Bewahrung bester Separation |
GB0226160D0 (en) * | 2002-11-08 | 2002-12-18 | Diagnoswiss Sa | Apparatus for dispensing a sample in electrospray mass spectrometers |
-
2002
- 2002-11-08 GB GBGB0226160.0A patent/GB0226160D0/en not_active Ceased
-
2003
- 2003-11-07 EP EP03812160A patent/EP1576642B1/de not_active Expired - Lifetime
- 2003-11-07 JP JP2004556196A patent/JP2006505797A/ja not_active Ceased
- 2003-11-07 AU AU2003302509A patent/AU2003302509A1/en not_active Abandoned
- 2003-11-07 US US10/534,301 patent/US7265348B2/en not_active Expired - Fee Related
- 2003-11-07 WO PCT/EP2003/013328 patent/WO2004051697A2/en active IP Right Grant
- 2003-11-07 DE DE60312220T patent/DE60312220T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7265348B2 (en) | 2007-09-04 |
GB0226160D0 (en) | 2002-12-18 |
EP1576642A2 (de) | 2005-09-21 |
JP2006505797A (ja) | 2006-02-16 |
EP1576642A3 (de) | 2005-11-16 |
AU2003302509A8 (en) | 2004-06-23 |
US20060113463A1 (en) | 2006-06-01 |
EP1576642B1 (de) | 2007-02-28 |
AU2003302509A1 (en) | 2004-06-23 |
WO2004051697A3 (en) | 2005-09-29 |
DE60312220T2 (de) | 2007-11-15 |
WO2004051697A2 (en) | 2004-06-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |