DE60310997D1 - Mikrofluides system mit stabilisierter flüssig-flüssig-grenzfläche - Google Patents

Mikrofluides system mit stabilisierter flüssig-flüssig-grenzfläche

Info

Publication number
DE60310997D1
DE60310997D1 DE60310997T DE60310997T DE60310997D1 DE 60310997 D1 DE60310997 D1 DE 60310997D1 DE 60310997 T DE60310997 T DE 60310997T DE 60310997 T DE60310997 T DE 60310997T DE 60310997 D1 DE60310997 D1 DE 60310997D1
Authority
DE
Germany
Prior art keywords
electrode
micro
channel
counter
fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60310997T
Other languages
English (en)
Other versions
DE60310997T2 (de
Inventor
Nicolas Sarrut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Application granted granted Critical
Publication of DE60310997D1 publication Critical patent/DE60310997D1/de
Publication of DE60310997T2 publication Critical patent/DE60310997T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3031—Micromixers using electro-hydrodynamic [EHD] or electro-kinetic [EKI] phenomena to mix or move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3039—Micromixers with mixing achieved by diffusion between layers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F2025/91—Direction of flow or arrangement of feed and discharge openings
    • B01F2025/917—Laminar or parallel flow, i.e. every point of the flow moves in layers which do not intermix
    • B01F2025/9171—Parallel flow, i.e. every point of the flow moves in parallel layers where intermixing can occur by diffusion or which do not intermix; Focusing, i.e. compressing parallel layers without intermixing them
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00853—Employing electrode arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE60310997T 2002-12-04 2003-11-27 Mikrofluides system mit stabilisierter flüssig-flüssig-grenzfläche Expired - Lifetime DE60310997T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0215254 2002-12-04
FR0215254A FR2848125B1 (fr) 2002-12-04 2002-12-04 Dispositif microfluidique dans lequel l'interface liquide/fluide est stabilisee
PCT/FR2003/003519 WO2004052542A1 (fr) 2002-12-04 2003-11-27 Dispositif microfluidique dans lequel l'interface liquide/fluide est stabilisee

Publications (2)

Publication Number Publication Date
DE60310997D1 true DE60310997D1 (de) 2007-02-15
DE60310997T2 DE60310997T2 (de) 2007-10-25

Family

ID=32319959

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60310997T Expired - Lifetime DE60310997T2 (de) 2002-12-04 2003-11-27 Mikrofluides system mit stabilisierter flüssig-flüssig-grenzfläche

Country Status (7)

Country Link
US (1) US7591936B2 (de)
EP (1) EP1567269B1 (de)
JP (1) JP4255914B2 (de)
AT (1) ATE350162T1 (de)
DE (1) DE60310997T2 (de)
FR (1) FR2848125B1 (de)
WO (1) WO2004052542A1 (de)

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US7605984B2 (en) * 2005-09-21 2009-10-20 National Tsing Hua University Lens with adjustable focal length
JP2009092483A (ja) * 2007-10-05 2009-04-30 Shimadzu Corp １８ｆ−イオン捕捉回収用フローセル及びその製造方法
US9206794B2 (en) 2008-04-28 2015-12-08 Nxp, B.V. Microfluidic pump with metal electrode having variable oxidation state
BRPI0921043A2 (pt) 2008-11-12 2018-08-07 Caris Life Sciences Luxembourg Holdings métodos e sistemas para usar exossomas para determinar fenótipos
EP2542696B1 (de) 2010-03-01 2016-09-28 Caris Life Sciences Switzerland Holdings GmbH Theranostik-biomarker
EP2556172A4 (de) 2010-04-06 2013-10-30 Caris Life Sciences Luxembourg Holdings Zirkulierende biomarker für krankheiten
US10942184B2 (en) 2012-10-23 2021-03-09 Caris Science, Inc. Aptamers and uses thereof
WO2014068408A2 (en) 2012-10-23 2014-05-08 Caris Life Sciences Switzerland Holdings, S.A.R.L. Aptamers and uses thereof
WO2014100434A1 (en) 2012-12-19 2014-06-26 Caris Science, Inc. Compositions and methods for aptamer screening
AU2014236262A1 (en) 2013-03-14 2015-10-15 The Board Of Trustees Of The Leland Stanford Junior University Capillary barriers for staged loading of microfluidic devices
CA2922689A1 (en) 2013-08-28 2015-03-05 Caris Life Sciences Switzerland Holdings Gmbh Oligonucleotide probes and uses thereof
US20180066262A1 (en) 2015-03-09 2018-03-08 Caris Science, Inc. Oligonucleotide probes and uses thereof
WO2016161402A1 (en) 2015-04-03 2016-10-06 Abbott Laboratories Devices and methods for sample analysis
MX2017012742A (es) * 2015-04-03 2017-11-15 Abbott Lab Dispositivos y metodos para el analisis de muestras.
EP3314027A4 (de) 2015-06-29 2019-07-03 Caris Science, Inc. Therapeutische oligonukleotide
EP3328873A4 (de) 2015-07-28 2019-04-10 Caris Science, Inc. Gezielte oligonukleotide
CN116083530A (zh) 2016-01-29 2023-05-09 普瑞珍生物系统公司 用于核酸纯化的等速电泳
CN109715802A (zh) 2016-03-18 2019-05-03 卡里斯科学公司 寡核苷酸探针及其用途
WO2017205686A1 (en) 2016-05-25 2017-11-30 Caris Science, Inc. Oligonucleotide probes and uses thereof
AU2018312570B2 (en) 2017-08-02 2024-01-11 Purigen Biosystems, Inc. Systems, devices, and methods for isotachophoresis
WO2019212989A1 (en) * 2018-04-30 2019-11-07 United Therapeutics Corporation Apparatus and method for controlling fluid flow
KR20210111254A (ko) 2018-11-30 2021-09-10 캐리스 엠피아이, 아이엔씨. 차세대 분자 프로파일링
IL293489A (en) 2019-12-02 2022-08-01 Caris Mpi Inc predictor of pan-cancer platinum response
CN115888597B (zh) * 2022-12-27 2023-07-25 宁波玄流智造有限公司 一种电化学微通道反应器

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418052A (en) * 1980-08-12 1983-11-29 Wong Dennis W Diagnostic compositions and method for radiologic imaging of fibrinogen deposition in the body
FR2543320B1 (fr) * 1983-03-23 1986-01-31 Thomson Csf Dispositif indicateur a commande electrique de deplacement d'un fluide
FR2548795B1 (fr) * 1983-07-04 1986-11-21 Thomson Csf Dispositif de commutation optique a deplacement de fluide et dispositif de composition d'une ligne de points
FR2710279B1 (fr) * 1993-09-23 1995-11-24 Armand Ajdari Perfectionnements aux procédés et dispositifs de séparation des particules contenues dans un fluide.
ATE175362T1 (de) 1994-10-22 1999-01-15 Central Research Lab Ltd Verfahren und vorrichtung für diffusionsaustausch zwischen nicht mischbare flüssigkeiten
US5699157A (en) * 1996-07-16 1997-12-16 Caliper Technologies Corp. Fourier detection of species migrating in a microchannel
US5992820A (en) * 1997-11-19 1999-11-30 Sarnoff Corporation Flow control in microfluidics devices by controlled bubble formation
WO2000060341A1 (en) * 1999-04-02 2000-10-12 Morphometrix Technologies Inc. Electro-osmotic pumping system and method
WO2000074850A2 (en) * 1999-06-03 2000-12-14 University Of Washington Microfluidic devices for transverse electrophoresis and isoelectric focusing
US6773566B2 (en) * 2000-08-31 2004-08-10 Nanolytics, Inc. Electrostatic actuators for microfluidics and methods for using same
US7016560B2 (en) * 2001-02-28 2006-03-21 Lightwave Microsystems Corporation Microfluidic control for waveguide optical switches, variable attenuators, and other optical devices
WO2002068821A2 (en) * 2001-02-28 2002-09-06 Lightwave Microsystems Corporation Microfluidic control using dieletric pumping

Also Published As

Publication number Publication date
JP2006508796A (ja) 2006-03-16
FR2848125B1 (fr) 2006-06-09
FR2848125A1 (fr) 2004-06-11
US7591936B2 (en) 2009-09-22
ATE350162T1 (de) 2007-01-15
JP4255914B2 (ja) 2009-04-22
EP1567269B1 (de) 2007-01-03
US20060042950A1 (en) 2006-03-02
DE60310997T2 (de) 2007-10-25
WO2004052542A1 (fr) 2004-06-24
EP1567269A1 (de) 2005-08-31

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