ATE350162T1 - Mikrofluides system mit stabilisierter flüssig- flüssig-grenzfläche - Google Patents

Mikrofluides system mit stabilisierter flüssig- flüssig-grenzfläche

Info

Publication number
ATE350162T1
ATE350162T1 AT03789521T AT03789521T ATE350162T1 AT E350162 T1 ATE350162 T1 AT E350162T1 AT 03789521 T AT03789521 T AT 03789521T AT 03789521 T AT03789521 T AT 03789521T AT E350162 T1 ATE350162 T1 AT E350162T1
Authority
AT
Austria
Prior art keywords
electrode
micro
liquid
channel
counter
Prior art date
Application number
AT03789521T
Other languages
English (en)
Inventor
Nicolas Sarrut
Original Assignee
Commissariat Energie Atomique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of ATE350162T1 publication Critical patent/ATE350162T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3031—Micromixers using electro-hydrodynamic [EHD] or electro-kinetic [EKI] phenomena to mix or move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3039—Micromixers with mixing achieved by diffusion between layers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F2025/91—Direction of flow or arrangement of feed and discharge openings
    • B01F2025/917—Laminar or parallel flow, i.e. every point of the flow moves in layers which do not intermix
    • B01F2025/9171—Parallel flow, i.e. every point of the flow moves in parallel layers where intermixing can occur by diffusion or which do not intermix; Focusing, i.e. compressing parallel layers without intermixing them
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00853—Employing electrode arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Organic Chemistry (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT03789521T 2002-12-04 2003-11-27 Mikrofluides system mit stabilisierter flüssig- flüssig-grenzfläche ATE350162T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0215254A FR2848125B1 (fr) 2002-12-04 2002-12-04 Dispositif microfluidique dans lequel l'interface liquide/fluide est stabilisee

Publications (1)

Publication Number Publication Date
ATE350162T1 true ATE350162T1 (de) 2007-01-15

Family

ID=32319959

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03789521T ATE350162T1 (de) 2002-12-04 2003-11-27 Mikrofluides system mit stabilisierter flüssig- flüssig-grenzfläche

Country Status (7)

Country Link
US (1) US7591936B2 (de)
EP (1) EP1567269B1 (de)
JP (1) JP4255914B2 (de)
AT (1) ATE350162T1 (de)
DE (1) DE60310997T2 (de)
FR (1) FR2848125B1 (de)
WO (1) WO2004052542A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7605984B2 (en) * 2005-09-21 2009-10-20 National Tsing Hua University Lens with adjustable focal length
JP2009092483A (ja) * 2007-10-05 2009-04-30 Shimadzu Corp １８ｆ−イオン捕捉回収用フローセル及びその製造方法
WO2009133499A2 (en) * 2008-04-28 2009-11-05 Nxp B.V. Microfluidic pump
US7897356B2 (en) 2008-11-12 2011-03-01 Caris Life Sciences Methods and systems of using exosomes for determining phenotypes
CA2791905A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Biomarkers for theranostics
US9469876B2 (en) 2010-04-06 2016-10-18 Caris Life Sciences Switzerland Holdings Gmbh Circulating biomarkers for metastatic prostate cancer
KR20150090072A (ko) 2012-10-23 2015-08-05 카리스 라이프 사이언스 스위스 홀딩스 게엠베하 압타머 및 이의 용도
US10942184B2 (en) 2012-10-23 2021-03-09 Caris Science, Inc. Aptamers and uses thereof
EP2935628B1 (de) 2012-12-19 2018-03-21 Caris Life Sciences Switzerland Holdings GmbH Zusammensetzungen und verfahren für aptamer-screening
CA2906730C (en) 2013-03-14 2023-03-21 Juan G. Santiago Capillary barriers for staged loading of microfluidic devices
CN105980615A (zh) 2013-08-28 2016-09-28 卡里斯生命科学瑞士控股有限公司 寡核苷酸探针及其用途
AU2016229076B2 (en) 2015-03-09 2022-01-20 Caris Science, Inc. Oligonucleotide probes and uses thereof
BR112017021256A2 (pt) 2015-04-03 2018-06-26 Abbott Laboratories dispositivos e métodos para a análise de amostras
WO2016161402A1 (en) 2015-04-03 2016-10-06 Abbott Laboratories Devices and methods for sample analysis
AU2016287499B2 (en) 2015-06-29 2022-08-04 Caris Science, Inc. Therapeutic oligonucleotides
US10941176B2 (en) 2015-07-28 2021-03-09 Caris Science, Inc. Therapeutic oligonucleotides
AU2017212754B2 (en) 2016-01-29 2023-06-29 Purigen Biosystems, Inc. Isotachophoresis for purification of nucleic acids
KR20190008843A (ko) 2016-03-18 2019-01-25 카리스 싸이언스, 인코포레이티드 올리고뉴클레오티드 프로브 및 이의 용도
IL306052A (en) 2016-05-25 2023-11-01 Caris Science Inc Oligonucleotide probes and their uses
JP7203106B2 (ja) 2017-08-02 2023-01-12 ピュリゲン バイオシステムズ インコーポレイテッド 等速電気泳動のためのシステム、装置および方法
CA3098891A1 (en) * 2018-04-30 2019-11-07 United Therapeutics Corporation Apparatus and method for controlling fluid flow
EP4369356A3 (de) 2018-11-30 2024-07-24 Caris MPI, Inc. Molekulare profilierung der nächsten generation
AU2020397802A1 (en) 2019-12-02 2022-06-16 Caris Mpi, Inc. Pan-cancer platinum response predictor
CN115888597B (zh) * 2022-12-27 2023-07-25 宁波玄流智造有限公司 一种电化学微通道反应器

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418052A (en) * 1980-08-12 1983-11-29 Wong Dennis W Diagnostic compositions and method for radiologic imaging of fibrinogen deposition in the body
FR2543320B1 (fr) * 1983-03-23 1986-01-31 Thomson Csf Dispositif indicateur a commande electrique de deplacement d'un fluide
FR2548795B1 (fr) * 1983-07-04 1986-11-21 Thomson Csf Dispositif de commutation optique a deplacement de fluide et dispositif de composition d'une ligne de points
FR2710279B1 (fr) * 1993-09-23 1995-11-24 Armand Ajdari Perfectionnements aux procédés et dispositifs de séparation des particules contenues dans un fluide.
EP0787029B1 (de) 1994-10-22 1999-01-07 Central Research Laboratories Limited Verfahren und vorrichtung für diffusionsaustausch zwischen nicht mischbare flüssigkeiten
US5699157A (en) * 1996-07-16 1997-12-16 Caliper Technologies Corp. Fourier detection of species migrating in a microchannel
US5992820A (en) * 1997-11-19 1999-11-30 Sarnoff Corporation Flow control in microfluidics devices by controlled bubble formation
AU3547200A (en) * 1999-04-02 2000-10-23 Morphometrix Technologies Inc. Electro-osmotic pumping system and method
WO2000074850A2 (en) * 1999-06-03 2000-12-14 University Of Washington Microfluidic devices for transverse electrophoresis and isoelectric focusing
US6773566B2 (en) * 2000-08-31 2004-08-10 Nanolytics, Inc. Electrostatic actuators for microfluidics and methods for using same
WO2002068821A2 (en) * 2001-02-28 2002-09-06 Lightwave Microsystems Corporation Microfluidic control using dieletric pumping
US7016560B2 (en) * 2001-02-28 2006-03-21 Lightwave Microsystems Corporation Microfluidic control for waveguide optical switches, variable attenuators, and other optical devices

Also Published As

Publication number Publication date
EP1567269B1 (de) 2007-01-03
WO2004052542A1 (fr) 2004-06-24
EP1567269A1 (de) 2005-08-31
FR2848125A1 (fr) 2004-06-11
FR2848125B1 (fr) 2006-06-09
JP2006508796A (ja) 2006-03-16
US7591936B2 (en) 2009-09-22
DE60310997T2 (de) 2007-10-25
DE60310997D1 (de) 2007-02-15
JP4255914B2 (ja) 2009-04-22
US20060042950A1 (en) 2006-03-02

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