DE60310695D1 - Amphiphile diblock-, triblock- und sternblockcopolymere und und diese enthaltende arzneimittel - Google Patents
Amphiphile diblock-, triblock- und sternblockcopolymere und und diese enthaltende arzneimittelInfo
- Publication number
- DE60310695D1 DE60310695D1 DE60310695T DE60310695T DE60310695D1 DE 60310695 D1 DE60310695 D1 DE 60310695D1 DE 60310695 T DE60310695 T DE 60310695T DE 60310695 T DE60310695 T DE 60310695T DE 60310695 D1 DE60310695 D1 DE 60310695D1
- Authority
- DE
- Germany
- Prior art keywords
- amphiphiles
- diblock
- triblock
- medicaments containing
- starblock copolymers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US101093 | 2002-03-18 | ||
US10/101,093 US7018655B2 (en) | 2002-03-18 | 2002-03-18 | Amphiphilic diblock, triblock and star-block copolymers and their pharmaceutical compositions |
PCT/CA2003/000376 WO2003078489A1 (en) | 2002-03-18 | 2003-03-17 | Amphiphilic diblock, triblock and star-block copolymers and their pharmaceutical compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60310695D1 true DE60310695D1 (de) | 2007-02-08 |
DE60310695T2 DE60310695T2 (de) | 2007-09-13 |
Family
ID=28039961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60310695T Expired - Lifetime DE60310695T2 (de) | 2002-03-18 | 2003-03-17 | Amphiphile diblock-, triblock- und sternblockcopolymere und und diese enthaltende arzneimittel |
Country Status (6)
Country | Link |
---|---|
US (1) | US7018655B2 (de) |
EP (1) | EP1487892B1 (de) |
AU (1) | AU2003212158A1 (de) |
DE (1) | DE60310695T2 (de) |
ES (1) | ES2278145T3 (de) |
WO (1) | WO2003078489A1 (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6939564B2 (en) * | 2001-06-08 | 2005-09-06 | Labopharm, Inc. | Water-soluble stabilized self-assembled polyelectrolytes |
WO2003031483A1 (en) | 2001-10-10 | 2003-04-17 | The Regents Of The University Of Colorado | Degradable thiol-ene polymers |
AU2003230761A1 (en) * | 2002-03-29 | 2003-10-13 | Abbott Laboratories | Polymeric micelle formulations of hydrophobic compounds and methods |
US20070155926A1 (en) * | 2003-03-28 | 2007-07-05 | Krzysztof Matyjaszewski | Degradable polymers |
TWI248947B (en) * | 2003-07-21 | 2006-02-11 | Ind Tech Res Inst | Biodegradable copolymer, and polymeric micelle composition containing the copolymer |
GB2408207A (en) * | 2003-11-24 | 2005-05-25 | Johnson & Johnson Medical Ltd | Wound dressing for the controlled release of therapeutic agents comprising also an inhibitor of a protease enzyme & a linker group cleavable by such an enzyme |
US7262253B2 (en) | 2003-12-02 | 2007-08-28 | Labopharm, Inc. | Process for the preparation of amphiphilic poly (N-vinyl-2-pyrrolidone) block copolymers |
US20050214379A1 (en) * | 2004-01-02 | 2005-09-29 | Sandro Mecozzi | Encapsulation of chemical compounds in fluorous-core and fluorous-inner-shell micelles formed from semifluorinated-block or fluorinated-block copolymers |
EP1725590A4 (de) * | 2004-03-05 | 2013-08-07 | Univ Carnegie Mellon | Verfahren zur atom transfer radical polymerization |
US20060198891A1 (en) * | 2004-11-29 | 2006-09-07 | Francois Ravenelle | Solid formulations of liquid biologically active agents |
JP4121537B2 (ja) | 2004-12-22 | 2008-07-23 | 日東電工株式会社 | 線維化抑制のための薬物担体および薬物担体キット |
US20120269886A1 (en) | 2004-12-22 | 2012-10-25 | Nitto Denko Corporation | Therapeutic agent for pulmonary fibrosis |
US20080268013A1 (en) * | 2005-02-10 | 2008-10-30 | Emory University | Polyethylene Oxide Polymers Including Anti-Inflammatory Glycodendrons |
CA2606270A1 (en) * | 2005-04-19 | 2006-10-26 | Massachusetts Institute Of Technology | Amphiphilic polymers and methods of use thereof |
EP1928919B1 (de) | 2005-08-23 | 2010-02-17 | Carnegie-Mellon University | Radikalische atomtransfer-polymerisation in mikroemulsion und echte emulsionspolymerisation |
DE602006017416D1 (de) * | 2005-08-26 | 2010-11-18 | Univ Carnegie Mellon | Polymerisationsverfahren mit katalysatorreaktivierung |
US20090298676A1 (en) * | 2005-10-26 | 2009-12-03 | Michael Meier | Unimolocular Micelles Containing Metal Nanoparticles and their Use as Catalyst for Synthesis of Carbon-Carbon-Bonds |
US9572886B2 (en) | 2005-12-22 | 2017-02-21 | Nitto Denko Corporation | Agent for treating myelofibrosis |
US7811555B2 (en) * | 2005-12-30 | 2010-10-12 | Cordis Corporation | Tri-branched biologically active copolymer |
WO2007084126A1 (en) * | 2006-01-19 | 2007-07-26 | Allexcel, Inc. | Solubilization and targeted delivery of drugs with self-assembling amphiphilic polymers |
WO2008004988A1 (en) * | 2006-07-06 | 2008-01-10 | Agency For Science, Technology And Research | Thermally responsive micelles |
US20080026062A1 (en) * | 2006-07-31 | 2008-01-31 | Isaac Farr | Pharmaceutical compositions including nano-sized active agent |
US20080026040A1 (en) * | 2006-07-31 | 2008-01-31 | Isaac Farr | Active agent-releasing dosage forms |
JP2010504318A (ja) * | 2006-09-22 | 2010-02-12 | ラボファーム インコーポレイテッド | pH標的化薬剤送達のための組成物及び方法 |
US8367051B2 (en) * | 2006-10-09 | 2013-02-05 | Carnegie Mellon University | Preparation of functional gel particles with a dual crosslink network |
US20080095847A1 (en) * | 2006-10-18 | 2008-04-24 | Thierry Glauser | Stimulus-release carrier, methods of manufacture and methods of treatment |
US9000048B2 (en) * | 2006-11-28 | 2015-04-07 | Wisconsin Alumni Research Foundation | Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics |
US8900562B2 (en) * | 2007-01-12 | 2014-12-02 | Wisconsin Alumni Research Foundation | Semi-fluorinated block copolymers for delivery of therapeutic agents |
TWI407971B (zh) | 2007-03-30 | 2013-09-11 | Nitto Denko Corp | Cancer cells and tumor-related fibroblasts |
GB2463198B (en) * | 2007-05-23 | 2013-05-22 | Univ Carnegie Mellon | Hybrid particle composite structures with reduced scattering |
WO2008148000A1 (en) | 2007-05-23 | 2008-12-04 | Carnegie Mellon University | Atom transfer dispersion polymerization |
TW200918099A (en) | 2007-09-14 | 2009-05-01 | Nitto Denko Corp | Drug carriers |
CA2635187A1 (en) | 2008-06-05 | 2009-12-05 | The Royal Institution For The Advancement Of Learning/Mcgill University | Oligonucleotide duplexes and uses thereof |
US8962764B2 (en) | 2009-03-27 | 2015-02-24 | Carnegie Mellon University | Preparation of functional star macromolecules |
CZ302830B6 (cs) | 2009-12-15 | 2011-11-30 | Ústav makromolekulární chemie AV CR, v.v.i. | Vysokomolekulární polymerní nosice léciv odvozené od dendrimeru a jejich konjugáty s lécivy pro lécbu zejména pevných nádoru |
EP2382966A1 (de) * | 2010-03-12 | 2011-11-02 | DSM IP Assets B.V. | Mizellenzusammensetzungen und Herstellungsverfahren dafür |
CN101845120B (zh) * | 2010-03-25 | 2011-11-16 | 淮阴师范学院 | 一种温敏和生物可降解性原位凝胶的合成方法 |
US9644042B2 (en) | 2010-12-17 | 2017-05-09 | Carnegie Mellon University | Electrochemically mediated atom transfer radical polymerization |
US20140038826A1 (en) | 2011-01-28 | 2014-02-06 | The Regents Of The University Of Colorado, A Body Corporate | Covalently cross linked hydrogels and methods of making and using same |
US8440772B2 (en) * | 2011-04-28 | 2013-05-14 | Chevron Phillips Chemical Company Lp | Methods for terminating olefin polymerizations |
EP2524690A1 (de) * | 2011-05-17 | 2012-11-21 | ETH Zurich | Verfahren zur Herstellung individuell angepasster Nanoteilchen, Nanoteilchen und deren Verwendung |
US8445577B2 (en) * | 2011-07-25 | 2013-05-21 | Iowa State University Research Foundation, Inc. | Amphiphilic multi-arm copolymers and nanomaterials derived therefrom |
WO2013028756A1 (en) | 2011-08-22 | 2013-02-28 | Carnegie Mellon University | Atom transfer radical polymerization under biologically compatible conditions |
US9988433B2 (en) | 2013-03-14 | 2018-06-05 | Mosaic Biosciences, Inc. | Covalent modification of biological macromolecules |
JP6004449B2 (ja) * | 2012-01-24 | 2016-10-05 | 国立大学法人 筑波大学 | トリブロックコポリマー及びその使用 |
WO2013116791A1 (en) | 2012-02-02 | 2013-08-08 | Mosaic Biosciences, Inc. | Biomaterials for delivery of blood extracts and methods of using same |
JP2015509129A (ja) * | 2012-02-03 | 2015-03-26 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション | 分岐ポリマー |
US9533297B2 (en) | 2012-02-23 | 2017-01-03 | Carnegie Mellon University | Ligands designed to provide highly active catalyst complexes |
ITRM20120169A1 (it) | 2012-04-19 | 2013-10-20 | Consiglio Nazionale Ricerche | Dispositivo di rilascio di specie chimiche a controllo ottico |
US10273315B2 (en) | 2012-06-20 | 2019-04-30 | Chevron Phillips Chemical Company Lp | Methods for terminating olefin polymerizations |
CN103965420B (zh) * | 2014-04-11 | 2016-05-25 | 西北师范大学 | 一种基于二硫键还原响应型可降解药物载体及其制备和应用 |
RU2580649C1 (ru) * | 2015-03-27 | 2016-04-10 | Общество С Ограниченной Ответственностью "Научно-Производственный Центр "Амфион" | Водосовместимые полимерные композиции для доставки биологически активных веществ |
RU2617059C2 (ru) * | 2014-11-11 | 2017-04-19 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" (ФГБНУ НИИВС им. И.И. Мечникова) | Способ получения амфифильных блок-сополимеров N,N-диметиламиноэтилметакрилата для доставки нуклеиновых кислот в живые клетки |
US10232050B1 (en) | 2014-12-12 | 2019-03-19 | Clemson University | Multi-functional particles and methods of using the same |
US11633355B2 (en) | 2014-12-12 | 2023-04-25 | Clemson University Research Foundation | Multi-functional particles and methods of using the same |
US9982070B2 (en) | 2015-01-12 | 2018-05-29 | Carnegie Mellon University | Aqueous ATRP in the presence of an activator regenerator |
US10912837B2 (en) | 2015-02-09 | 2021-02-09 | Mosaic Biosciences, Inc. | Degradable thiol-ene polymers and methods of making thereof |
CN105213307B (zh) * | 2015-09-30 | 2018-02-13 | 天津大学 | 用于粘液渗透的还原响应性靶向高分子胶束及其制备方法 |
US11174325B2 (en) | 2017-01-12 | 2021-11-16 | Carnegie Mellon University | Surfactant assisted formation of a catalyst complex for emulsion atom transfer radical polymerization processes |
CN108078926B (zh) * | 2017-12-20 | 2020-07-07 | 临沂大学 | 一种肿瘤主动靶向星形两亲聚合物胶束纳米药物及其制备方法 |
EP3680273B1 (de) * | 2019-01-08 | 2022-03-09 | Université de Montpellier | Mit photoreaktiven gruppen funktionalisierter verzweigter blockcopolymer-photovernetzer und dessen verwendung zur formgebung von degradierbaren, für medizinische und gewebetechnische anwendungen geeigneten photovernetzten elastomeren |
CN110144032B (zh) * | 2019-05-23 | 2021-10-26 | 西京学院 | 一种四臂星状聚合物及其制备方法 |
FI129022B (en) | 2019-09-10 | 2021-05-14 | Aabo Akademi Univ | Polymer and composition made from a renewable source |
CN111019109A (zh) * | 2019-12-26 | 2020-04-17 | 南京林业大学 | 一种聚d-乳酸-异丙叉基葡萄糖双嵌段共聚物材料及其制备方法 |
WO2023210671A1 (ja) * | 2022-04-26 | 2023-11-02 | 京セラ株式会社 | 共重合体、高分子膜、測定用装置および測定用担体 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4016332A (en) * | 1972-05-01 | 1977-04-05 | Ppg Industries, Inc. | Mercaptan blocked thermosetting copolymers |
US3933940A (en) * | 1973-02-08 | 1976-01-20 | Ppg Industries, Inc. | Mercaptan blocked thermosetting copolymers |
DE3378250D1 (en) * | 1982-04-22 | 1988-11-24 | Ici Plc | Continuous release formulations |
US4565854A (en) * | 1983-04-07 | 1986-01-21 | Kuraray Co., Ltd. | Polymer having thiol end group |
US5342724A (en) * | 1992-04-10 | 1994-08-30 | Eastman Kodak Company | Toner manufacture using chain transfer polyesters |
CA2228118A1 (en) | 1995-07-28 | 1997-02-13 | Focal, Inc. | Multiblock biodegradable hydrogels for use as controlled release agents for drugs delivery and tissue treatments agents |
KR0180334B1 (ko) | 1995-09-21 | 1999-03-20 | 김윤 | 블럭 공중합체 미셀을 이용한 약물전달체 및 이에 약물을 봉입하는 방법 |
US6284267B1 (en) | 1996-08-14 | 2001-09-04 | Nutrimed Biotech | Amphiphilic materials and liposome formulations thereof |
US6060518A (en) | 1996-08-16 | 2000-05-09 | Supratek Pharma Inc. | Polymer compositions for chemotherapy and methods of treatment using the same |
TW520297B (en) * | 1996-10-11 | 2003-02-11 | Sequus Pharm Inc | Fusogenic liposome composition and method |
US6338859B1 (en) * | 2000-06-29 | 2002-01-15 | Labopharm Inc. | Polymeric micelle compositions |
-
2002
- 2002-03-18 US US10/101,093 patent/US7018655B2/en not_active Expired - Lifetime
-
2003
- 2003-03-17 ES ES03707970T patent/ES2278145T3/es not_active Expired - Lifetime
- 2003-03-17 EP EP03707970A patent/EP1487892B1/de not_active Expired - Lifetime
- 2003-03-17 DE DE60310695T patent/DE60310695T2/de not_active Expired - Lifetime
- 2003-03-17 AU AU2003212158A patent/AU2003212158A1/en not_active Abandoned
- 2003-03-17 WO PCT/CA2003/000376 patent/WO2003078489A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ES2278145T3 (es) | 2007-08-01 |
EP1487892A1 (de) | 2004-12-22 |
AU2003212158A1 (en) | 2003-09-29 |
WO2003078489A1 (en) | 2003-09-25 |
US20030181613A1 (en) | 2003-09-25 |
US7018655B2 (en) | 2006-03-28 |
EP1487892B1 (de) | 2006-12-27 |
DE60310695T2 (de) | 2007-09-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: LABOPHARM INC., LAVAL, QUEBEC, CA Owner name: LABOPHARM EUROPE LTD., DUBLIN, IE Owner name: LABOPHARM (BARBADOS) LTD., BELLEVILLE, ST. MIC, BB |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: SCHIEBER FARAGO, 80538 MUENCHEN |
|
8364 | No opposition during term of opposition |