AU2003214387A1 - Drug carriers comprising amphiphilic block copolymers - Google Patents

Drug carriers comprising amphiphilic block copolymers

Info

Publication number
AU2003214387A1
AU2003214387A1 AU2003214387A AU2003214387A AU2003214387A1 AU 2003214387 A1 AU2003214387 A1 AU 2003214387A1 AU 2003214387 A AU2003214387 A AU 2003214387A AU 2003214387 A AU2003214387 A AU 2003214387A AU 2003214387 A1 AU2003214387 A1 AU 2003214387A1
Authority
AU
Australia
Prior art keywords
block copolymers
amphiphilic block
drug carriers
carriers
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003214387A
Inventor
Steven Peter Armes
Andrew William Lewis
Andrew P. Lloyd
Jonathan P. Salvage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocompatibles UK Ltd
Original Assignee
Biocompatibles UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocompatibles UK Ltd filed Critical Biocompatibles UK Ltd
Publication of AU2003214387A1 publication Critical patent/AU2003214387A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
AU2003214387A 2002-03-07 2003-03-07 Drug carriers comprising amphiphilic block copolymers Abandoned AU2003214387A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02251505 2002-03-07
EP02251505.0 2002-03-07
PCT/GB2003/000958 WO2003074026A1 (en) 2002-03-07 2003-03-07 Drug carriers comprising amphiphilic block copolymers

Publications (1)

Publication Number Publication Date
AU2003214387A1 true AU2003214387A1 (en) 2003-09-16

Family

ID=27771936

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003214387A Abandoned AU2003214387A1 (en) 2002-03-07 2003-03-07 Drug carriers comprising amphiphilic block copolymers

Country Status (4)

Country Link
US (2) US20050220880A1 (en)
EP (1) EP1480619B1 (en)
AU (1) AU2003214387A1 (en)
WO (1) WO2003074026A1 (en)

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DE60334779D1 (en) 2002-03-07 2010-12-16 Biocompatibles Uk Ltd Mit nucleinsäure complexierte block-copolymere
WO2003082303A1 (en) * 2002-03-29 2003-10-09 Wisconsin Alumni Research Foundation Polymeric micelle formulations of hydrophobic compounds and methods
GB0301014D0 (en) 2003-01-16 2003-02-19 Biocompatibles Ltd Conjugation reactions
EP1590388A2 (en) * 2003-02-05 2005-11-02 Biocompatibles UK Limited Block copolymers
CA2548376A1 (en) * 2003-12-31 2005-07-21 Pfizer Products Inc. Solid compositions of low-solubility drugs and poloxamers
US20050214379A1 (en) * 2004-01-02 2005-09-29 Sandro Mecozzi Encapsulation of chemical compounds in fluorous-core and fluorous-inner-shell micelles formed from semifluorinated-block or fluorinated-block copolymers
KR100732013B1 (en) * 2005-03-18 2007-06-25 성균관대학교산학협력단 pH SENSITIVE BLOCK COPOLYMER AND POLYMERIC MICELLE USING THE SAME
WO2006113666A2 (en) * 2005-04-19 2006-10-26 Massachusetts Institute Of Technology Amphiphilic polymers and methods of use thereof
US8124128B2 (en) 2005-11-08 2012-02-28 Industrial Technology Research Institute Amphiphilic block copolymers and nano particles comprising the same
GB0524740D0 (en) * 2005-12-03 2006-01-11 Univ Sheffield Polymer gelator
JP5528710B2 (en) 2006-02-28 2014-06-25 オリガシス コーポレイション Polymer conjugate containing acryloyloxyethyl phosphorylcholine and process for producing the same
EP2065056B1 (en) * 2006-08-29 2016-09-28 FUJIFILM Corporation Hydrophilic matrix containing poorly water-soluble compound and method for producing the same
GB0617480D0 (en) 2006-09-06 2006-10-18 Univ Sheffield Novel nanoparticles
JP5557373B2 (en) 2006-11-21 2014-07-23 アボット ラボラトリーズ Use of terpolymers of tetrafluoroethylene, hexafluoropropylene, and vinylidene fluoride in drug-eluting coatings
EP2099408B1 (en) * 2006-11-28 2016-10-05 Wisconsin Alumni Research Foundation Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics
US8597673B2 (en) * 2006-12-13 2013-12-03 Advanced Cardiovascular Systems, Inc. Coating of fast absorption or dissolution
JP2010530955A (en) * 2006-12-29 2010-09-16 ユニヴァーシティ オブ ワシントン Dual functional non-polluting surfaces and materials
US8900562B2 (en) * 2007-01-12 2014-12-02 Wisconsin Alumni Research Foundation Semi-fluorinated block copolymers for delivery of therapeutic agents
JP2010536738A (en) * 2007-08-16 2010-12-02 バイオコンパティブルズ ユーケー リミテッド Delivery of drug combinations
US20110129921A1 (en) * 2008-05-13 2011-06-02 University Of Washington Targeted polymer bioconjugates
CA2724014C (en) 2008-05-13 2016-09-13 University Of Washington Micellic assemblies
BRPI0912159B8 (en) 2008-05-13 2021-05-25 Phaserx Inc copolymer comprising a first block comprising a hydrophilic unit at physiological pH and a second block comprising hydrophobic groups, and use of said copolymer for intracellular release of a polynucleotide
JP2011523641A (en) * 2008-05-13 2011-08-18 ユニヴァーシティ オブ ワシントン Polymer carrier
CA2724472A1 (en) * 2008-05-13 2009-11-19 University Of Washington Micelles for intracellular delivery of therapeutic agents
EP2144062A1 (en) 2008-05-15 2010-01-13 Biocompatibles UK Limited Method of monitoring live cells
US9211250B2 (en) 2008-08-22 2015-12-15 University Of Washington Heterogeneous polymeric micelles for intracellular delivery
ES2540767T3 (en) 2008-11-06 2015-07-13 University Of Washington Multi-block copolymers
WO2010053596A1 (en) 2008-11-06 2010-05-14 University Of Washington Bispecific intracellular delivery vehicles
EP2373715A4 (en) 2008-12-08 2014-12-03 Univ Washington Omega-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, and radical chain extension polymerization
CA2756072A1 (en) * 2009-03-30 2010-10-14 Cerulean Pharma Inc. Polymer-agent conjugates, particles, compositions, and related methods of use
WO2010114768A1 (en) * 2009-03-30 2010-10-07 Cerulean Pharma Inc. Polymer-epothilone conjugates, particles, compositions, and related methods of use
CN101869712B (en) 2009-04-21 2016-01-20 财团法人工业技术研究院 The polymeric micelle of encapsulation antitumor drug is used to be used for the treatment of the pharmaceutical composition of tumor
US9415113B2 (en) 2009-11-18 2016-08-16 University Of Washington Targeting monomers and polymers having targeting blocks
US8765432B2 (en) 2009-12-18 2014-07-01 Oligasis, Llc Targeted drug phosphorylcholine polymer conjugates
AU2016203456B2 (en) * 2010-09-22 2017-10-05 The Board Of Regents Of The University Of Texas System Novel block copolymer and micelle compositions and methods of use thereof
AU2015203892B2 (en) * 2010-09-22 2016-03-10 The Board Of Regents Of The University Of Texas System Novel block copolymer and micelle compositions and methods of use thereof
AU2011306076B2 (en) 2010-09-22 2015-05-07 The Board Of Regents Of The University Of Texas System Novel block copolymer and micelle compositions and methods of use thereof
WO2012040513A1 (en) * 2010-09-22 2012-03-29 The Board Of Regents Of The University Of Texas System Compositions and methods for the delivery of beta lapachone
US10031138B2 (en) 2012-01-20 2018-07-24 University Of Washington Through Its Center For Commercialization Hierarchical films having ultra low fouling and high recognition element loading properties
US9511152B2 (en) 2012-04-05 2016-12-06 The Board Of Regents Of The University Of Texas System Multicolored pH-activatable fluorescence nanoplatform
MY185109A (en) 2012-05-22 2021-04-30 Dsm Ip Assets Bv Composition and process for making a porous inorganic oxide coating
EP3027221A1 (en) 2013-07-30 2016-06-08 PhaseRx, Inc. Block copolymers and their conjugates or complexes with oligonucleotides
US10702608B2 (en) 2013-09-08 2020-07-07 Kodiak Sciences Inc. Factor VIII zwitterionic polymer conjugates
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
JP6849590B2 (en) 2014-10-17 2021-03-24 コディアック サイエンシーズ インコーポレイテッドＫｏｄｉａｋ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． Butyrylcholinesterase amphoteric ionic polymer conjugate
WO2016118697A1 (en) 2015-01-21 2016-07-28 Phaserx, Inc. Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells
SG11201805420SA (en) 2015-12-30 2018-07-30 Kodiak Sciences Inc Antibodies and conjugates thereof
EP3562510A4 (en) 2016-12-30 2021-01-06 Genevant Sciences GmbH Branched peg molecules and related compositions and methods
EP4041312A4 (en) 2019-10-10 2023-12-20 Kodiak Sciences Inc. Methods of treating an eye disorder
WO2021217111A1 (en) 2020-04-24 2021-10-28 The Board Of Regents Of The University Of Texas System Ph responsive block copolymer compositions and micelles that inhibit mct 1 and related proteins
CN116217768A (en) * 2023-03-27 2023-06-06 华南理工大学 Amphiphilic ionic polymer PMPC-ODA and preparation method thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093391A (en) * 1992-10-08 2000-07-25 Supratek Pharma, Inc. Peptide copolymer compositions
US5846558A (en) * 1996-03-19 1998-12-08 Minnesota Mining And Manufacturing Company Ionically conductive adhesives prepared from zwitterionic materials and medical devices using such adhesives
DE60129148T2 (en) 2000-10-06 2008-02-28 Biocompatibles Uk Ltd., Farnham TWITTER POLYMERS
ATE371680T1 (en) * 2002-01-16 2007-09-15 Biocompatibles Uk Ltd POLYMER CONJUGATES
DE60334779D1 (en) * 2002-03-07 2010-12-16 Biocompatibles Uk Ltd Mit nucleinsäure complexierte block-copolymere
GB0301014D0 (en) * 2003-01-16 2003-02-19 Biocompatibles Ltd Conjugation reactions
EP1590388A2 (en) * 2003-02-05 2005-11-02 Biocompatibles UK Limited Block copolymers

Also Published As

Publication number Publication date
US9765213B2 (en) 2017-09-19
US20050220880A1 (en) 2005-10-06
US20120157550A1 (en) 2012-06-21
EP1480619B1 (en) 2013-08-07
WO2003074026A1 (en) 2003-09-12
EP1480619A1 (en) 2004-12-01

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase