DE60307463D1 - Elektrospray-tandem-massenspektrometrie zur untersuchung von neugeborenen - Google Patents

Elektrospray-tandem-massenspektrometrie zur untersuchung von neugeborenen

Info

Publication number
DE60307463D1
DE60307463D1 DE60307463T DE60307463T DE60307463D1 DE 60307463 D1 DE60307463 D1 DE 60307463D1 DE 60307463 T DE60307463 T DE 60307463T DE 60307463 T DE60307463 T DE 60307463T DE 60307463 D1 DE60307463 D1 DE 60307463D1
Authority
DE
Germany
Prior art keywords
mass spectrometry
tandem mass
analysis
acids
newborn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60307463T
Other languages
English (en)
Other versions
DE60307463T2 (de
Inventor
C Dooley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IZAAK WALTON KILLAM HEALTH CT
Original Assignee
IZAAK WALTON KILLAM HEALTH CT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IZAAK WALTON KILLAM HEALTH CT filed Critical IZAAK WALTON KILLAM HEALTH CT
Publication of DE60307463D1 publication Critical patent/DE60307463D1/de
Application granted granted Critical
Publication of DE60307463T2 publication Critical patent/DE60307463T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/20Oxygen containing
    • Y10T436/200833Carbonyl, ether, aldehyde or ketone containing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
DE60307463T 2002-06-05 2003-06-02 Elektrospray-tandem-massenspektrometrie zur untersuchung von neugeborenen Expired - Fee Related DE60307463T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/163,625 US6800489B2 (en) 2002-06-05 2002-06-05 Electrospray tandem mass spectrometry of transition metal diimine complexes of amino acids, α-hydroxyketones and hexose phosphates for newborn screening
US163625 2002-06-05
PCT/CA2003/000789 WO2003104802A1 (en) 2002-06-05 2003-06-02 Electrospray tandem mass spectrometry for newborn screening

Publications (2)

Publication Number Publication Date
DE60307463D1 true DE60307463D1 (de) 2006-09-21
DE60307463T2 DE60307463T2 (de) 2007-03-29

Family

ID=29710012

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60307463T Expired - Fee Related DE60307463T2 (de) 2002-06-05 2003-06-02 Elektrospray-tandem-massenspektrometrie zur untersuchung von neugeborenen

Country Status (6)

Country Link
US (1) US6800489B2 (de)
EP (1) EP1512006B1 (de)
AT (1) ATE336000T1 (de)
AU (1) AU2003232539A1 (de)
DE (1) DE60307463T2 (de)
WO (1) WO2003104802A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2519557C (en) * 2003-04-14 2013-02-19 Georgetown University Steroid hormone analysis by mass spectrometry
WO2007130629A1 (en) * 2006-05-05 2007-11-15 Perkinelmer Las, Inc Quantitative analysis of surface-derived samples using mass spectrometry
US7923257B2 (en) * 2007-05-04 2011-04-12 Perkinelmer Health Sciences, Inc. Detecting isomers using differential derivatization mass spectrometry
WO2010075449A1 (en) 2008-12-24 2010-07-01 Quest Diagnostics Investments Incorporated Mass spectrometry assay for congenital adrenal hyperplasia
WO2014086361A1 (en) * 2012-12-03 2014-06-12 Statens Serum Institut Method of diagnosing galactosemia in neonatal screening

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5581286A (en) 1991-12-31 1996-12-03 Compaq Computer Corporation Multi-channel array actuation system for an ink jet printhead
GB9817845D0 (en) 1998-08-17 1998-10-14 Glaxo Group Ltd Chemical compounds
US6258605B1 (en) 1999-03-26 2001-07-10 Neo Gen Screening, Inc. Clinical method for the genetic screening of newborns using tandem mass spectrometry
US6455321B1 (en) * 1999-01-30 2002-09-24 Neo Gen Screening, Inc. Method for interpreting tandem mass spectrometry data for clinical diagnosis
DE60031357T2 (de) * 1999-12-29 2007-08-30 PerkinElmer Life Sciences, Inc., Norton Geräte, Kits und Verfahren zum Testen von Körperflüssigkeiten zum Screening vonNeugeborenen durch Tandem-Massenspektrometrie-Kits
BR0111473A (pt) * 2000-06-07 2004-01-13 Univ Duke Métodos para triar um indivìduo quanto a uma doença de armazenagem de glicogênio, para triar um indivìduo quanto à doença de pompe, para monitorar a condição clìnica de um indivìduo com doença de pompe, para estimar a eficácia de um regime terapêutico em um indivìduo com doença de pompe e para determinar a concentração de um oligossacarìdeo em uma amostra biológica
US6451611B1 (en) 2000-07-28 2002-09-17 Statens Serum Institute Quantitative analysis of hexose-monophosphates from biological samples

Also Published As

Publication number Publication date
ATE336000T1 (de) 2006-09-15
WO2003104802A1 (en) 2003-12-18
EP1512006A1 (de) 2005-03-09
DE60307463T2 (de) 2007-03-29
US20030228704A1 (en) 2003-12-11
AU2003232539A1 (en) 2003-12-22
US6800489B2 (en) 2004-10-05
EP1512006B1 (de) 2006-08-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee