DE60232912D1 - Optischer fluoreszenzsensor mit hoher leistung - Google Patents

Optischer fluoreszenzsensor mit hoher leistung

Info

Publication number
DE60232912D1
DE60232912D1 DE60232912T DE60232912T DE60232912D1 DE 60232912 D1 DE60232912 D1 DE 60232912D1 DE 60232912 T DE60232912 T DE 60232912T DE 60232912 T DE60232912 T DE 60232912T DE 60232912 D1 DE60232912 D1 DE 60232912D1
Authority
DE
Germany
Prior art keywords
waveguide
light source
light
indicator matrix
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60232912T
Other languages
English (en)
Inventor
Arthur E Colvin
Steven J Walters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sensors for Medecine and Science Inc
Original Assignee
Sensors for Medecine and Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sensors for Medecine and Science Inc filed Critical Sensors for Medecine and Science Inc
Application granted granted Critical
Publication of DE60232912D1 publication Critical patent/DE60232912D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/064Stray light conditioning
    • G01N2201/0642Light traps; baffles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Luminescent Compositions (AREA)
DE60232912T 2001-12-11 2002-12-11 Optischer fluoreszenzsensor mit hoher leistung Expired - Lifetime DE60232912D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33864701P 2001-12-11 2001-12-11
PCT/US2002/039675 WO2003050519A1 (en) 2001-12-11 2002-12-11 High performance fluorescent optical sensor

Publications (1)

Publication Number Publication Date
DE60232912D1 true DE60232912D1 (de) 2009-08-20

Family

ID=23325537

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60232912T Expired - Lifetime DE60232912D1 (de) 2001-12-11 2002-12-11 Optischer fluoreszenzsensor mit hoher leistung

Country Status (13)

Country Link
US (2) US6940590B2 (de)
EP (1) EP1454129B1 (de)
JP (1) JP4430396B2 (de)
CN (2) CN101819149B (de)
AT (1) ATE436011T1 (de)
AU (1) AU2002359673B2 (de)
BR (1) BR0214824A (de)
CA (1) CA2469870C (de)
DE (1) DE60232912D1 (de)
HK (2) HK1064442A1 (de)
MX (1) MXPA04005608A (de)
TW (1) TWI293363B (de)
WO (1) WO2003050519A1 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
WO2002078512A2 (en) 2001-04-02 2002-10-10 Therasense, Inc. Blood glucose tracking apparatus and methods
US6844563B2 (en) * 2001-05-22 2005-01-18 Matsushita Electric Industrial Co., Ltd. Fluorescence detecting device with integrated circuit and photodiode, and detection method
AU2003287735A1 (en) * 2002-11-12 2004-06-03 Argose, Inc. Non-invasive measurement of analytes
US20040106163A1 (en) * 2002-11-12 2004-06-03 Workman Jerome James Non-invasive measurement of analytes
AU2003303597A1 (en) 2002-12-31 2004-07-29 Therasense, Inc. Continuous glucose monitoring system and methods of use
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US7799276B2 (en) 2003-10-27 2010-09-21 Michigan Molecular Institute Functionalized particles for composite sensors
US8029765B2 (en) * 2003-12-24 2011-10-04 Masimo Laboratories, Inc. SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
US7221455B2 (en) * 2004-01-20 2007-05-22 The Regents Of The Unversity Of California Integrated, fluorescence-detecting microanalytical system
CA2556331A1 (en) 2004-02-17 2005-09-29 Therasense, Inc. Method and system for providing data communication in continuous glucose monitoring and management system
JP4593957B2 (ja) * 2004-03-31 2010-12-08 テルモ株式会社 電子光学式検出装置
US7375347B2 (en) * 2004-04-26 2008-05-20 Sensors For Medicine And Science, Inc. Systems and methods for extending the useful life of optical sensors
JP4558448B2 (ja) * 2004-11-01 2010-10-06 テルモ株式会社 光導波路およびこの光導波路を用いた蛍光センサ
US7280201B2 (en) * 2004-12-17 2007-10-09 Avago Technologies General Ip Pte Ltd Sensor having integrated light detector and/or light source
US20060241351A1 (en) * 2005-04-08 2006-10-26 Rosemount Analytical Inc. Integrated optical device for luminescence sensing
US7308292B2 (en) 2005-04-15 2007-12-11 Sensors For Medicine And Science, Inc. Optical-based sensing devices
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
WO2007027634A2 (en) * 2005-08-31 2007-03-08 Stratagene California Compact optical module for fluorescence excitation and detection
CN101395463B (zh) * 2005-09-22 2011-05-25 皇家飞利浦电子股份有限公司 包括至少两个线栅的发光传感器
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US20080071157A1 (en) 2006-06-07 2008-03-20 Abbott Diabetes Care, Inc. Analyte monitoring system and method
DE602007005501D1 (de) * 2006-09-28 2010-05-06 Philips Intellectual Property Feststofflichtquelle mit farbreflexion und kombinierten kommunikationsmitteln
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
MX2011001114A (es) * 2008-07-28 2011-04-21 Sensors For Med & Science Inc Sistemas y metodos para la medicion optica de la concentracion de analitos.
KR20110069084A (ko) * 2008-09-19 2011-06-22 센서즈 포 메드슨 앤드 사이언스 인코포레이티드 광학 센서 조립체
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US9184490B2 (en) 2009-05-29 2015-11-10 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
WO2011026148A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
EP2473098A4 (de) 2009-08-31 2014-04-09 Abbott Diabetes Care Inc Analytsignalverarbeitungsvorrichtung und -verfahren
EP2482720A4 (de) 2009-09-29 2014-04-23 Abbott Diabetes Care Inc Verfahren und vorrichtung zur bereitstellung einer benachrichtigungsfunktion in analytüberwachungssystemen
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
CN110604585B (zh) 2010-10-06 2023-04-18 普罗弗萨股份有限公司 组织整合性传感器
JP2012093190A (ja) * 2010-10-26 2012-05-17 Olympus Corp 蛍光センサの補正方法おび蛍光センサ
CA2830432C (en) 2011-03-15 2022-04-26 Senseonics, Incorporated Integrated catalytic protection of oxidation sensitive materials
EP2775918B1 (de) 2011-11-07 2020-02-12 Abbott Diabetes Care Inc. Analytüberwachungsvorrichtung und -verfahren
WO2013084975A1 (ja) * 2011-12-08 2013-06-13 オリンパス株式会社 蛍光センサおよび蛍光センサの製造方法
US8906320B1 (en) 2012-04-16 2014-12-09 Illumina, Inc. Biosensors for biological or chemical analysis and systems and methods for same
US9883824B2 (en) * 2012-08-20 2018-02-06 Taiwan Biophotonic Corporation Detecting device
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
WO2014045761A1 (ja) * 2012-09-21 2014-03-27 テルモ株式会社 蛍光センサ
WO2014045385A1 (ja) * 2012-09-21 2014-03-27 テルモ株式会社 蛍光センサ
CN113274007A (zh) 2013-03-14 2021-08-20 普罗菲尤萨股份有限公司 用于校正光学信号的方法和装置
US20140275843A1 (en) * 2013-03-15 2014-09-18 James S. Piccirillo Continuous optode fluorescent measurement system
ITVR20130132A1 (it) * 2013-05-29 2014-11-30 Optoelettronica Italia S R L Kit per il rilevamento di micro-rna estratto da un campione di fluido corporeo nonché metodo per il rilevamento dello stesso
US9963556B2 (en) 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
AT14051U1 (de) * 2013-10-23 2015-03-15 Tecsense Gmbh Optochemischer Sensor
EP4220137A1 (de) 2013-12-10 2023-08-02 Illumina, Inc. Biosensoren zur biologischen oder chemischen analyse und verfahren zur herstellung davon
WO2015108294A1 (en) * 2014-01-15 2015-07-23 Samsung Electronics Co., Ltd. Optical sensor and electronic device with the same
US9322756B2 (en) * 2014-02-21 2016-04-26 Maxim Integrated Products, Inc. Nondispersive infrared micro-optics sensor for blood alcohol concentration measurements
WO2016014987A2 (en) 2014-07-24 2016-01-28 Thomas Jefferson University Long-term implantable monitoring system & methods of use
WO2016039721A1 (en) * 2014-09-08 2016-03-17 Empire Technology Development Llc Integrated packaging for multi-component sensors
BR112017028113A2 (pt) * 2015-06-25 2018-08-28 Profusa Inc leitora transcutânea para uso com sensores de analito transplantáveis
US9945790B2 (en) * 2015-08-05 2018-04-17 Viavi Solutions Inc. In-situ spectral process monitoring
US11331018B2 (en) 2016-12-22 2022-05-17 Profusa, Inc. System and single-channel biosensor for and method of determining analyte value
JP6944259B2 (ja) * 2017-03-27 2021-10-06 グローリー株式会社 燐光検出装置、紙葉類処理装置及び燐光検出方法
JP7017862B2 (ja) * 2017-03-27 2022-02-09 グローリー株式会社 光センサ、光検出装置、紙葉類処理装置及び光検出方法
WO2018181134A1 (ja) * 2017-03-27 2018-10-04 グローリー株式会社 光センサ、光検出装置、紙葉類処理装置、光検出方法及び燐光検出装置
JP6944258B2 (ja) * 2017-03-27 2021-10-06 グローリー株式会社 燐光検出装置、紙葉類処理装置及び燐光検出方法
WO2018184012A1 (en) 2017-03-31 2018-10-04 Capillary Biomedical, Inc. Helical insertion infusion device
CA3076468C (en) * 2017-09-22 2024-03-26 Lawrence Livermore National Security, Llc Photoconductive charge trapping apparatus
MY194772A (en) 2017-12-26 2022-12-15 Illumina Inc Sensor System
US11287312B2 (en) 2018-05-09 2022-03-29 Advanced Semiconductor Engineering, Inc. Optical system and method of manufacturing the same
US10811400B2 (en) * 2018-09-28 2020-10-20 Apple Inc. Wafer level optical module
EP3767276A1 (de) * 2019-07-19 2021-01-20 Sensirion AG Sensor für organischen gesamtkohlenstoff mit uv-sensitivem photodetektor, welcher eine abwärtswandelnde schicht enthält
US11951186B2 (en) 2019-10-25 2024-04-09 Willow Laboratories, Inc. Indicator compounds, devices comprising indicator compounds, and methods of making and using the same
KR102306147B1 (ko) * 2020-05-29 2021-09-29 주식회사 수젠텍 검체 내 분석물을 검출하기 위한 디바이스
CN111755557A (zh) * 2020-06-18 2020-10-09 深圳市兴邦维科科技有限公司 一种接近传感器整合型封装结构
AT524748B1 (de) 2021-02-19 2023-03-15 Johannes Krottmaier Dr Optische Einheit für die Messung von Fluoreszenzlicht

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244394B1 (de) * 1986-04-23 1992-06-17 AVL Medical Instruments AG Sensorelement zur Bestimmung von Stoffkonzentrationen
AT390677B (de) * 1986-10-10 1990-06-11 Avl Verbrennungskraft Messtech Sensorelement zur bestimmung von stoffkonzentrationen
US4906100A (en) 1988-05-13 1990-03-06 University Of Cincinnati Method of detecting adriamycin (doxorubicin) or daunomycin in the environment
JPH07119690B2 (ja) 1989-03-17 1995-12-20 富士ゼロックス株式会社 光学式ガス検知装置
US5018866A (en) 1989-09-12 1991-05-28 Packard Instrument Company Method and apparatus for performing high sensitivity fluorescence measurements
US5453248A (en) 1992-03-09 1995-09-26 Optical Sensors Incorporated Cross-linked gas permeable membrane of a cured perfluorinated urethane polymer, and optical gas sensors fabricated therewith
US5737457A (en) * 1994-02-25 1998-04-07 Fci - Fiberchem, Inc. Chip level waveguide sensor
US5439647A (en) 1994-02-25 1995-08-08 Fiberchem, Inc. Chip level waveguide sensor
US5517313A (en) * 1995-02-21 1996-05-14 Colvin, Jr.; Arthur E. Fluorescent optical sensor
DE69733650T2 (de) * 1996-03-01 2006-04-20 Beckman Coulter, Inc., Fullerton System zum simultanen Durchführen einer Vielzahl von Ligandenbindungs-Untersuchungen
US5919710A (en) 1996-07-18 1999-07-06 The United States Of America As Represented By The Secretary Of The Air Force Optical method for quantitating dissolved oxygen in fuel
US6111248A (en) * 1996-10-01 2000-08-29 Texas Instruments Incorporated Self-contained optical sensor system
JPH10132749A (ja) * 1996-10-01 1998-05-22 Texas Instr Inc <Ti> 集積蛍光生化学センサ
EP0834735A3 (de) * 1996-10-01 1999-08-11 Texas Instruments Inc. Sensor
US6119031A (en) * 1996-11-21 2000-09-12 Boston Scientific Corporation Miniature spectrometer
US5894351A (en) 1997-05-13 1999-04-13 Colvin, Jr.; Arthur E. Fluorescence sensing device
US5917605A (en) 1997-05-13 1999-06-29 Colvin, Jr.; Arthur E. Fluorescence sensing device
US5910661A (en) 1997-05-13 1999-06-08 Colvin, Jr.; Arthur E. Flourescence sensing device
ES2306525T3 (es) * 1998-08-26 2008-11-01 Sensors For Medicine And Science, Inc. Dispositivos de deteccion basados en optica.
US6304766B1 (en) * 1998-08-26 2001-10-16 Sensors For Medicine And Science Optical-based sensing devices, especially for in-situ sensing in humans

Also Published As

Publication number Publication date
JP4430396B2 (ja) 2010-03-10
CN1602420A (zh) 2005-03-30
HK1064442A1 (en) 2005-01-28
CA2469870A1 (en) 2003-06-19
US7190445B2 (en) 2007-03-13
EP1454129A4 (de) 2006-08-02
TW200303984A (en) 2003-09-16
AU2002359673B2 (en) 2009-01-08
JP2005513426A (ja) 2005-05-12
US20030156290A1 (en) 2003-08-21
CN1602420B (zh) 2010-05-26
CN101819149A (zh) 2010-09-01
BR0214824A (pt) 2004-09-14
ATE436011T1 (de) 2009-07-15
MXPA04005608A (es) 2004-12-06
CA2469870C (en) 2011-07-26
AU2002359673A1 (en) 2003-06-23
US6940590B2 (en) 2005-09-06
US20050237518A1 (en) 2005-10-27
EP1454129A1 (de) 2004-09-08
TWI293363B (en) 2008-02-11
WO2003050519A1 (en) 2003-06-19
HK1148067A1 (en) 2011-08-26
CN101819149B (zh) 2012-06-13
EP1454129B1 (de) 2009-07-08

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