DE60230894D1 - - Google Patents

Info

Publication number
DE60230894D1
DE60230894D1 DE60230894T DE60230894T DE60230894D1 DE 60230894 D1 DE60230894 D1 DE 60230894D1 DE 60230894 T DE60230894 T DE 60230894T DE 60230894 T DE60230894 T DE 60230894T DE 60230894 D1 DE60230894 D1 DE 60230894D1
Authority
DE
Germany
Prior art keywords
attached
facet
abrading
skin
handle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230894T
Other languages
English (en)
Inventor
John A Mikszta
Ronald J Pettis
Jason Alarcon
John M Brittingham
John Dekker Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of DE60230894D1 publication Critical patent/DE60230894D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/54Chiropodists' instruments, e.g. pedicure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B2017/320004Surgical cutting instruments abrasive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Coating Apparatus (AREA)
DE60230894T 2001-10-29 2002-10-29 Expired - Lifetime DE60230894D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33071301P 2001-10-29 2001-10-29
US33316201P 2001-11-27 2001-11-27
PCT/US2002/034504 WO2003051284A2 (en) 2001-10-29 2002-10-29 Method and device for the delivery of a substance

Publications (1)

Publication Number Publication Date
DE60230894D1 true DE60230894D1 (de) 2009-03-05

Family

ID=26987410

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230894T Expired - Lifetime DE60230894D1 (de) 2001-10-29 2002-10-29

Country Status (12)

Country Link
US (1) US20030093040A1 (de)
EP (1) EP1439870B1 (de)
JP (1) JP2005511248A (de)
CN (1) CN1662266A (de)
AT (1) ATE420676T1 (de)
AU (1) AU2002365144A1 (de)
BR (1) BR0213686A (de)
CA (1) CA2464994A1 (de)
DE (1) DE60230894D1 (de)
ES (1) ES2319625T3 (de)
MX (1) MXPA04003953A (de)
WO (1) WO2003051284A2 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6641591B1 (en) 1999-08-26 2003-11-04 John H. Shadduck Instruments and techniques for controlled removal of epidermal layers
US20060018877A1 (en) * 2001-06-29 2006-01-26 Mikszta John A Intradermal delivery of vacccines and therapeutic agents
CN1253220C (zh) * 2001-06-29 2006-04-26 贝克顿迪肯森公司 通过微管在真皮内输入疫苗和基因治疗剂
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
JP4469610B2 (ja) * 2002-02-04 2010-05-26 ベクトン・ディキンソン・アンド・カンパニー 皮膚アクセス部材
KR20120087197A (ko) 2002-07-19 2012-08-06 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법
CA2497154C (en) * 2002-08-29 2012-01-03 Becton, Dickinson And Company Substance delivery via a rotating microabrading surface
CA2530531A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
US8961477B2 (en) * 2003-08-25 2015-02-24 3M Innovative Properties Company Delivery of immune response modifier compounds
EP1682012A4 (de) * 2003-11-13 2008-09-24 Alza Corp Zusammensetzung und gerät zur transdermalen abgabe
JP2007523771A (ja) * 2004-02-23 2007-08-23 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの成形方法
SE0402100D0 (sv) * 2004-08-30 2004-08-30 Bonsens Ab Molded micro-needles
WO2006031500A2 (en) * 2004-09-10 2006-03-23 Becton, Dickinson And Company Reconstituting infusion device
US20070053965A1 (en) * 2005-02-25 2007-03-08 Gruenenthal Gmbh Kit comprising a plaster, optionally containing an active substance, and an agent that at least partially reduces skin irritation
CN101242869B (zh) * 2005-09-02 2010-05-26 Iomai公司 经皮递送疫苗和透皮递送药物的装置及其应用
DE102005044737A1 (de) * 2005-09-19 2007-03-29 Braun Gmbh Verfahren zum Entfernen von Haaren, Haarentfernungsgerät und Aufsatz hierfür
WO2007061964A1 (en) 2005-11-18 2007-05-31 3M Innovative Properties Company Methods for coating microneedles
WO2007064486A1 (en) * 2005-11-30 2007-06-07 3M Innovative Properties Company Microneedle arrays and methods of use thereof
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
EP1971278A4 (de) * 2006-01-12 2009-12-23 Nano Pass Technologies Ltd Verfahren zur oberflächlichen schleifbehandlung der haut
US10172644B2 (en) 2006-03-29 2019-01-08 Edge Systems Llc Devices, systems and methods for treating the skin
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
EP2021021A2 (de) * 2006-05-12 2009-02-11 Oklahoma Medical Research Foundation Anthrax-zusammensetzungen und verfahren zu ihrer herstellung und anwendung
WO2008096732A1 (ja) * 2007-02-06 2008-08-14 Hisamitsu Pharmaceutical Co., Inc. アレルギー診断用マイクロニードルデバイス
EP2240099B1 (de) 2008-01-04 2018-02-21 Edge Systems LLC Vorrichtung zur hautbehandlung
WO2009097451A1 (en) 2008-01-29 2009-08-06 Edge Systems Corporation Apparatus and method for treating the skin
US8814836B2 (en) 2008-01-29 2014-08-26 Edge Systems Llc Devices, systems and methods for treating the skin using time-release substances
US20110159035A1 (en) * 2008-08-01 2011-06-30 Masahiro Goto S/o type transdermal immunizing agent
WO2011005894A1 (en) * 2009-07-07 2011-01-13 Naya Touch, Inc. Dermal roller with therapeutic microstructures
GB201007207D0 (en) * 2010-04-29 2010-06-16 Univ Cork Method
JP5788019B2 (ja) * 2011-11-18 2015-09-30 南部化成株式会社 経皮投薬装置
US9044582B2 (en) * 2012-06-26 2015-06-02 Franklin J. Chang Apparatus and method for transdermal fluid delivery
US10238812B2 (en) 2013-03-15 2019-03-26 Edge Systems Llc Skin treatment systems and methods using needles
EP2967633B1 (de) 2013-03-15 2018-04-25 Edge Systems LLC Vorrichtungen zur hautbehandlung
US10194935B2 (en) * 2013-12-31 2019-02-05 L'oreal Shear-induced dermal infusion
CN106535858A (zh) * 2014-03-26 2017-03-22 纳诺麦德皮肤护理公司 用于液体或固体成分的经皮和透皮递送的柱塞状物质传送装置
TR201905846T4 (tr) * 2014-12-18 2019-05-21 Koninklijke Philips Nv Mikrodermabrazyon cihazı.
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
EP3795204B1 (de) 2014-12-23 2023-10-25 HydraFacial LLC Vorrichtung zur behandlung der haut mittels eines rollballens
EP4197517A1 (de) 2015-07-08 2023-06-21 HydraFacial LLC Vorrichtungen, systeme und verfahren zur förderung des haarwachstums
CN108056845A (zh) * 2017-12-15 2018-05-22 深圳清华大学研究院 一种侧路腰椎椎间融合器
EP3856761A1 (de) 2018-09-24 2021-08-04 Krystal Biotech, Inc. Zusammensetzungen und verfahren zur behandlung des netherton-syndroms
EP4294446A1 (de) * 2021-02-18 2023-12-27 Agonex Biopharmaceuticals, Inc. Systeme, vorrichtungen und formulierungen zur zeitphasen-histaminfreisetzung
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device
GB2622416A (en) * 2022-09-15 2024-03-20 Ndm Tech Ltd Skin preparation device

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3289670A (en) * 1964-03-09 1966-12-06 Milo Bundy Corp Device for abrading and applying biologicals to the skin of a patient
US3556080A (en) * 1968-04-08 1971-01-19 Lincoln Lab Inc Skin allergy testing device
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
OA05448A (fr) * 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
US4270548A (en) * 1979-09-05 1981-06-02 Aller-Screen, Inc. Allergy testing method
FR2474856A1 (fr) * 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
FR2498443B2 (fr) * 1981-01-26 1986-03-28 Merieux Inst Dispositif scarificateur
US4483348A (en) * 1982-03-25 1984-11-20 Nathan Sher Skin testing device
US4597764A (en) * 1983-09-28 1986-07-01 Bruce Black Ossicular replacement prosthesis
US4568343A (en) * 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
US4746515A (en) * 1987-02-26 1988-05-24 Alza Corporation Skin permeation enhancer compositions using glycerol monolaurate
AU614092B2 (en) * 1987-09-11 1991-08-22 Paul Max Grinwald Improved method and apparatus for enhanced drug permeation of skin
TW279133B (de) * 1990-12-13 1996-06-21 Elan Med Tech
US5273528A (en) * 1992-07-10 1993-12-28 Skeen Mikell L Livestock inoculator
DE4307869C2 (de) * 1993-03-12 1996-04-04 Microparts Gmbh Mikrostrukturkörper und Verfahren zu deren Herstellung
US5679647A (en) * 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5885211A (en) * 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5380337A (en) * 1994-01-24 1995-01-10 Romaine; Richard A. Mesh-type skin biopsy appliance
US5660680A (en) * 1994-03-07 1997-08-26 The Regents Of The University Of California Method for fabrication of high vertical aspect ratio thin film structures
JP2551742B2 (ja) * 1994-05-23 1996-11-06 三星電機株式会社 医薬品投与用皮膚傷形成装置
US5591139A (en) * 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
US6368333B2 (en) * 1994-06-29 2002-04-09 Mattioli Engineering Ltd. V-shaped handpiece for dermabrasion
AU5740496A (en) * 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
WO1996037256A1 (en) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
US5958589A (en) * 1995-07-07 1999-09-28 The United States Of America As Represented By The Secretary Of Agriculture Starch-based microcellular foams
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5658515A (en) * 1995-09-25 1997-08-19 Lee; Abraham P. Polymer micromold and fabrication process
US6032060A (en) * 1996-01-25 2000-02-29 3M Innovative Properties Company Method for conditioning skin and an electrode by passing electrical energy
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
US5919364A (en) * 1996-06-24 1999-07-06 Regents Of The University Of California Microfabricated filter and shell constructed with a permeable membrane
DE69722414T2 (de) * 1996-07-03 2004-05-19 Altea Therapeutics Corp. Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
US5983136A (en) * 1996-09-17 1999-11-09 Deka Products Limited Partnership System for delivery of drugs by transport
US5910306A (en) * 1996-11-14 1999-06-08 The United States Of America As Represented By The Secretary Of The Army Transdermal delivery system for antigen
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US6065864A (en) * 1997-01-24 2000-05-23 The Regents Of The University Of California Apparatus and method for planar laminar mixing
US5928207A (en) * 1997-06-30 1999-07-27 The Regents Of The University Of California Microneedle with isotropically etched tip, and method of fabricating such a device
US5999847A (en) * 1997-10-21 1999-12-07 Elstrom; John A. Apparatus and method for delivery of surgical and therapeutic agents
US6077229A (en) * 1997-10-21 2000-06-20 Pitesky; Isadore Allergy testing apparatus
US5931794A (en) * 1997-10-21 1999-08-03 Pitesky; Isadore Allergy testing apparatus
ATE221400T1 (de) * 1997-12-11 2002-08-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
US5970998A (en) * 1998-02-27 1999-10-26 The Regents Of The University Of California Microfabricated cantilever ratchet valve, and method for using same
US6173202B1 (en) * 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
US6106751A (en) * 1998-03-18 2000-08-22 The Regents Of The University Of California Method for fabricating needles via conformal deposition in two-piece molds
US7004933B2 (en) * 1998-05-29 2006-02-28 Light Bioscience L.L.C. Ultrasound enhancement of percutaneous drug absorption
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6162232A (en) * 1999-03-18 2000-12-19 Shadduck; John H. Instruments and techniques for high-velocity fluid abrasion of epidermal layers with skin cooling
US6582442B2 (en) * 2000-02-28 2003-06-24 Dynatronics Corporation Method and system for performing microabrasion
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6312612B1 (en) * 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US6331266B1 (en) * 1999-09-29 2001-12-18 Becton Dickinson And Company Process of making a molded device
ATE295200T1 (de) * 1999-12-10 2005-05-15 Alza Corp Hautbehandlungsvorrichtung zur verlängerten transdermalen verabreichung von medikamenten
CA2394171A1 (en) * 1999-12-16 2001-06-21 Alza Corporation Device for enhancing transdermal flux of sampled agents
US6706032B2 (en) * 2000-06-08 2004-03-16 Massachusetts Institute Of Technology Localized molecular and ionic transport to and from tissues
MXPA03003303A (es) * 2000-10-13 2004-12-13 Johnson & Johnson Retenedor del miembro de microprotrusion para aplicador de impacto.
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
WO2003026732A2 (en) * 2001-09-28 2003-04-03 Biovalve Technologies, Inc. Switchable microneedle arrays and systems and methods relating to same

Also Published As

Publication number Publication date
ATE420676T1 (de) 2009-01-15
US20030093040A1 (en) 2003-05-15
WO2003051284A2 (en) 2003-06-26
CN1662266A (zh) 2005-08-31
EP1439870B1 (de) 2009-01-14
MXPA04003953A (es) 2004-06-18
CA2464994A1 (en) 2003-06-26
AU2002365144A1 (en) 2003-06-30
BR0213686A (pt) 2006-05-23
EP1439870A4 (de) 2006-03-01
JP2005511248A (ja) 2005-04-28
ES2319625T3 (es) 2009-05-11
EP1439870A2 (de) 2004-07-28
WO2003051284A3 (en) 2004-01-29

Similar Documents

Publication Publication Date Title
DE60230894D1 (de)
EP1875993A3 (de) Rasierergriff mit ergonomischen Griffbereichen
EP1120087A3 (de) Vorrichtung zur Befestigung von Gewebereparaturmaterial an einem Knochen
WO2004082469A3 (en) Skin treatment system and method of use
HK1178105A1 (zh) 用於噴漆槍的流體儲存器
WO2003073917A3 (en) Microdermabrasion fluid application system and method
WO2007027349A3 (en) Sizing apparatus
EP1321154A3 (de) Bioabsorbierbare Beschichtungen für chirurgische Artikel
EP1529479A3 (de) Bodenreinigungsgerät
ATE308355T1 (de) Vorrichtung zur abgabe von medien
ATE505150T1 (de) Vorrichtung zur entfernung von zahnschmelz bei personen
AU2002346481A1 (en) Microdermabrasion system and method of use
HUP0204345A2 (hu) Csiszolókorong
WO2006019646A3 (en) Napkin dispenser
EP4248829A3 (de) Oberflächenreinigungsvorrichtung mit aufgabenbeleuchtung
MY142089A (en) Polishing system comprising a highly branched polymer
WO2002058752A3 (en) Medical device and methods of use
EP1397057A4 (de) Nagelschere
AU2003292219A8 (en) Devices coated with substances that mediate the adhesion of biological material
AU2002302593A1 (en) Pillow, especially for use during therapeutic measures
US6540582B1 (en) Multi-tool apparatus for friction game cells
CA2477653A1 (en) Puncturing means for use in an inhalation device
EP1318424A3 (de) Berührungsfreie Haltevorrichtung für ein optisches Element
AU2002251132A1 (en) Device for surface treatment of objects with reduced size and improved ergonomics
GB2304965B (en) Nail treatment training device

Legal Events

Date Code Title Description
8364 No opposition during term of opposition