DE60230138D1 - Vor missbrauch geschützte opioid-haltige transdermale systeme - Google Patents

Vor missbrauch geschützte opioid-haltige transdermale systeme

Info

Publication number
DE60230138D1
DE60230138D1 DE60230138T DE60230138T DE60230138D1 DE 60230138 D1 DE60230138 D1 DE 60230138D1 DE 60230138 T DE60230138 T DE 60230138T DE 60230138 T DE60230138 T DE 60230138T DE 60230138 D1 DE60230138 D1 DE 60230138D1
Authority
DE
Germany
Prior art keywords
misuse
transdermale
opioid
protected
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230138T
Other languages
German (de)
English (en)
Inventor
Lino Tavares
Bruce Reidenberg
Richard S Sackler
Curtis Wright
Mark A Alfonso
Benjamin Oshlack
James P Cassidy
Anthony E Carpanzano
Rampurna Prasad Gullapalli
Ihor Shevchuk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Application granted granted Critical
Publication of DE60230138D1 publication Critical patent/DE60230138D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B2101/00—Type of solid waste
    • B09B2101/65—Medical waste
    • B09B2101/68—Transdermal patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60230138T 2001-05-01 2002-04-30 Vor missbrauch geschützte opioid-haltige transdermale systeme Expired - Lifetime DE60230138D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28787501P 2001-05-01 2001-05-01
US29253701P 2001-05-22 2001-05-22
PCT/US2002/014073 WO2002087482A1 (en) 2001-05-01 2002-04-30 Abuse resistant opioid containing transdermal systems

Publications (1)

Publication Number Publication Date
DE60230138D1 true DE60230138D1 (de) 2009-01-15

Family

ID=26964697

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230138T Expired - Lifetime DE60230138D1 (de) 2001-05-01 2002-04-30 Vor missbrauch geschützte opioid-haltige transdermale systeme

Country Status (11)

Country Link
US (2) US20040241218A1 (https=)
EP (3) EP2062573B1 (https=)
JP (3) JP5296284B2 (https=)
AT (2) ATE533478T1 (https=)
CY (2) CY1108821T1 (https=)
DE (1) DE60230138D1 (https=)
DK (3) DK2062573T3 (https=)
ES (3) ES2318010T3 (https=)
PT (3) PT2062573E (https=)
SI (3) SI2062573T1 (https=)
WO (1) WO2002087482A1 (https=)

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ES2283812T3 (es) * 2002-06-10 2007-11-01 Euro Celtique Sa Sistemas de eliminacion de dispositivos de adminsitracion transdemica para prevenir el uso indebido de los agentes activos contenidos en los mismos.
US7815934B2 (en) * 2002-09-20 2010-10-19 Alpharma Pharmaceuticals, Llc Sequestering subunit and related compositions and methods
DE10250088A1 (de) * 2002-10-25 2004-05-06 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
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US7182955B2 (en) * 2003-04-30 2007-02-27 3M Innovative Properties Company Abuse-resistant transdermal dosage form
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WO2006023644A2 (en) * 2004-08-20 2006-03-02 3M Innovative Properties Company Transdermal drug delivery device with translucent protective film
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US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
SI1814531T1 (sl) * 2004-10-21 2010-10-29 Durect Corp Transdermalni dostavni sistem
WO2006069008A1 (en) * 2004-12-22 2006-06-29 Vesta Medical, Llc Compositions and devices for inactivation of pharmaceuticals to facilitate waste disposal, and methods thereof
US20060182819A1 (en) * 2005-02-17 2006-08-17 Ough Yon D Soap scent patch and treatment for muscle spasm and pain
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
EP1898891A2 (en) * 2005-05-13 2008-03-19 Alza Corporation Multilayer drug delivery system with barrier against antagonist exposure
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US20070014839A1 (en) * 2005-07-18 2007-01-18 Stefan Bracht Decomposer film for transdermal patches
US9056061B2 (en) 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
US8383149B2 (en) 2005-09-23 2013-02-26 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
EP1968539A2 (en) * 2005-12-13 2008-09-17 Biodelivery Sciences International, Inc. Abuse resistant transmucosal drug delivery device
DE102006025282A1 (de) * 2006-05-31 2007-12-20 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System
SI2719378T1 (sl) 2006-06-19 2016-11-30 Alpharma Pharmaceuticals Llc Farmacevtski sestavki
US20080008747A1 (en) * 2006-07-07 2008-01-10 Royds Robert B Transdermal patch
DK2054031T3 (en) 2006-07-21 2016-05-17 Biodelivery Sciences Int Inc Transmucosal delivery devices with improved uptake
WO2008063301A2 (en) * 2006-10-11 2008-05-29 Alpharma, Inc. Pharmaceutical compositions
US20080286348A1 (en) * 2007-05-16 2008-11-20 Todhunter John A Secured transdermal delivery system
DE102007041557B4 (de) * 2007-08-29 2011-03-31 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend längliche Hohlkörper
US20090196890A1 (en) * 2007-12-17 2009-08-06 Alpharma Pharmaceuticals, Llc Pharmaceutical compositions
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
JP2011515495A (ja) * 2008-03-26 2011-05-19 オールトランツ インコーポレイティド オピエートアゴニスト及びアゴニスト−アンタゴニストの乱用抑制経皮製剤
DE102008016804B4 (de) * 2008-04-02 2012-01-05 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System mit verbesserter Funktionalität und Wirksamkeit sowie seine Verwendung
JP2013523780A (ja) * 2010-04-02 2013-06-17 オールトランツ インコーポレイティド オピエートアゴニスト及びアゴニスト−アンタゴニストの乱用抑止性経皮製剤
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
AU2012296346A1 (en) 2011-08-18 2014-04-03 Biodelivery Sciences International, Inc. Abuse-resistant mucoadhesive devices for delivery of buprenorphine
WO2013049380A1 (en) 2011-09-30 2013-04-04 Teikoku Pharma Usa, Inc. Transdermal patch disposal system
JP2014528276A (ja) 2011-09-30 2014-10-27 テイコク ファーマ ユーエスエー インコーポレーテッド 一般用医薬品廃棄システム
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
WO2016049266A1 (en) * 2014-09-24 2016-03-31 Pain Therapeutics, Inc. 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal
US10010543B1 (en) 2014-12-23 2018-07-03 Barr Laboratories, Inc. Transdermal dosage form
AU2016211330A1 (en) 2015-01-28 2017-08-03 Chrono Therapeutics Inc. Drug delivery methods and systems
US10679516B2 (en) 2015-03-12 2020-06-09 Morningside Venture Investments Limited Craving input and support system
WO2017147568A1 (en) * 2016-02-26 2017-08-31 Case Western Reserve University Composite membranes for flow batteries
CA3049529A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
US11389844B2 (en) 2018-03-20 2022-07-19 Verde Environmental Technologies, Inc. Blister pack disposal system
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
WO2020008366A1 (en) * 2018-07-02 2020-01-09 Clexio Biosciences Ltd. Transdermal dosage form
WO2020009685A1 (en) * 2018-07-02 2020-01-09 John Tang Transdermal dosage form
US20210346662A1 (en) * 2018-10-23 2021-11-11 Kindeva Drug Delivery L.P. Tamper evident transdermal patch
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
CN114401746A (zh) * 2019-08-12 2022-04-26 耶路撒冷希伯来大学伊森姆研究发展有限公司 包括鸦片拮抗剂组合的药学组合物及复合材料及其使用方法

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US5236714A (en) 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US5149538A (en) * 1991-06-14 1992-09-22 Warner-Lambert Company Misuse-resistive transdermal opioid dosage form
US6096756A (en) * 1992-09-21 2000-08-01 Albert Einstein College Of Medicine Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
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Also Published As

Publication number Publication date
EP1397095A4 (en) 2005-05-25
EP2316439A1 (en) 2011-05-04
ES2318010T3 (es) 2009-05-01
EP1397095A1 (en) 2004-03-17
EP1397095B1 (en) 2008-12-03
EP2062573A1 (en) 2009-05-27
JP2004529155A (ja) 2004-09-24
DK1397095T3 (da) 2009-03-09
DK2316439T3 (en) 2015-08-10
SI2062573T1 (sl) 2012-02-29
US20140199383A1 (en) 2014-07-17
US20040241218A1 (en) 2004-12-02
ATE415952T1 (de) 2008-12-15
PT1397095E (pt) 2009-02-17
EP2316439B1 (en) 2015-06-17
PT2316439E (pt) 2015-08-28
JP2013144702A (ja) 2013-07-25
CY1108821T1 (el) 2014-04-09
ES2546828T3 (es) 2015-09-29
EP2062573B1 (en) 2011-11-16
JP5296284B2 (ja) 2013-09-25
JP2015042649A (ja) 2015-03-05
SI2316439T1 (sl) 2015-10-30
DK2062573T3 (da) 2012-01-30
WO2002087482A1 (en) 2002-11-07
ES2377672T3 (es) 2012-03-29
CY1112271T1 (el) 2015-12-09
ATE533478T1 (de) 2011-12-15
PT2062573E (pt) 2012-01-11
SI1397095T1 (sl) 2009-04-30

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: TAVARES, LINO, KINNELON, NJ 07405, US

Inventor name: REIDENBERG, BRUCE E., RYE, NY 10580, US

Inventor name: SACKLER, RICHARD S., GREENWICH CT 06830, US

Inventor name: SHEVCHUK, IHOR, YONKERS, NY 10710, US

Inventor name: GULLAPALLI, RAMPURNA PRASAD, ELMSFORD, NY 1052, US

Inventor name: CARPANZANO, ANTHONY E., SHERMAN, CT 06784, US

Inventor name: CASSIDY, JAMES P., CORTLANDT MANOR, NY 10567, US

Inventor name: OSHLACK, BENJAMIN, NEW YORK, NY 10028, US

Inventor name: ALFONSO, MARK A., EASTON, CT 06612, US

Inventor name: WRIGHT, CURTIS, NORWALK, CT 06851, US

8364 No opposition during term of opposition