DE60223133D1 - Verfahren zum lokalisieren und identifizieren von epitopen - Google Patents

Verfahren zum lokalisieren und identifizieren von epitopen

Info

Publication number
DE60223133D1
DE60223133D1 DE60223133T DE60223133T DE60223133D1 DE 60223133 D1 DE60223133 D1 DE 60223133D1 DE 60223133 T DE60223133 T DE 60223133T DE 60223133 T DE60223133 T DE 60223133T DE 60223133 D1 DE60223133 D1 DE 60223133D1
Authority
DE
Germany
Prior art keywords
localizing
epitopes
identifying epitopes
electron microscopy
labeling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60223133T
Other languages
English (en)
Other versions
DE60223133T2 (de
DE60223133T9 (de
Inventor
Ulf Skoglund
Neus Visa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIDEC TECHNOLOGIES AB
Original Assignee
SIDEC TECHNOLOGIES AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SIDEC TECHNOLOGIES AB filed Critical SIDEC TECHNOLOGIES AB
Publication of DE60223133D1 publication Critical patent/DE60223133D1/de
Publication of DE60223133T2 publication Critical patent/DE60223133T2/de
Application granted granted Critical
Publication of DE60223133T9 publication Critical patent/DE60223133T9/de
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J2237/00—Discharge tubes exposing object to beam, e.g. for analysis treatment, etching, imaging
    • H01J2237/26—Electron or ion microscopes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60223133T 2001-03-05 2002-02-28 Verfahren zum lokalisieren und identifizieren von epitopen Expired - Fee Related DE60223133T9 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0100728 2001-03-05
SE0100728A SE0100728D0 (sv) 2001-03-05 2001-03-05 New method
PCT/SE2002/000354 WO2002071336A1 (en) 2001-03-05 2002-02-28 Method for localizing and identifying epitopes

Publications (3)

Publication Number Publication Date
DE60223133D1 true DE60223133D1 (de) 2007-12-06
DE60223133T2 DE60223133T2 (de) 2008-08-28
DE60223133T9 DE60223133T9 (de) 2009-05-20

Family

ID=20283204

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60223133T Expired - Fee Related DE60223133T9 (de) 2001-03-05 2002-02-28 Verfahren zum lokalisieren und identifizieren von epitopen

Country Status (7)

Country Link
US (2) US20040137519A1 (de)
EP (1) EP1366468B1 (de)
JP (1) JP2004530119A (de)
AT (1) ATE376697T1 (de)
DE (1) DE60223133T9 (de)
SE (1) SE0100728D0 (de)
WO (1) WO2002071336A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004068415A1 (en) * 2003-01-30 2004-08-12 Sidec Technologies Ab Method for high-resolution 3d reconstruction
WO2007100293A1 (en) * 2006-03-01 2007-09-07 Sidec Technologies Ab Method of applying alignment markers for cryo-microscopy
FR2908235B1 (fr) * 2006-11-07 2009-01-16 Inst Nat Sciences Appliq Equipement pour la tomographie d'un echantillon
WO2012038484A1 (en) * 2010-09-21 2012-03-29 University Of Utrecht Holding B.V. Method of preparing a biological sample for inspection with electron microscopy and fluorescent light microscopy
US9594032B2 (en) 2013-03-13 2017-03-14 Okinawa Institute Of Science And Technology School Corporation Extended field iterative reconstruction technique (EFIRT) for correlated noise removal
JP6699044B2 (ja) * 2016-03-15 2020-05-27 国立大学法人山梨大学 染色方法および観察方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2567068B2 (ja) * 1988-10-28 1996-12-25 日本電信電話株式会社 電子顕微鏡検体調整法及び電子顕微鏡検体調整器具
EP0339980B1 (de) * 1988-04-26 1994-07-20 Nippon Telegraph And Telephone Corporation Mikropartikel, Verfahren und Gerät zur Sammlung von Proben zur Verwendung bei der Markierung von Immunreaktionen und Verfahren und Gerät zur Bereitung von Proben
US4925648A (en) * 1988-07-29 1990-05-15 Immunomedics, Inc. Detection and treatment of infectious and inflammatory lesions
FR2656129B1 (fr) * 1989-12-20 1992-03-13 Gen Electric Cgr Procede de reconstruction multi-echelle de l'image de la structure d'un corps.
US5401625A (en) * 1993-06-24 1995-03-28 E. K. Industries, Inc. Histological composition for light microscopy
US5910486A (en) * 1994-09-06 1999-06-08 Uab Research Foundation Methods for modulating protein function in cells using, intracellular antibody homologues
SE9601229D0 (sv) * 1996-03-07 1996-03-29 B Ulf Skoglund Apparatus and method for providing reconstruction
US6289235B1 (en) * 1998-03-05 2001-09-11 Wake Forest University Method and system for creating three-dimensional images using tomosynthetic computed tomography
US6372512B1 (en) * 1998-09-16 2002-04-16 Resolution Sciences Corporation Combined en bloc staining and embedding process
WO2000075868A2 (en) * 1999-06-07 2000-12-14 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for use in three-dimensional structural determination
JP2001004631A (ja) * 1999-06-25 2001-01-12 Shokuhin Sangyo Center 磁気ビーズ固定化抗体を用いた微生物の迅速検定法
US6683316B2 (en) * 2001-08-01 2004-01-27 Aspex, Llc Apparatus for correlating an optical image and a SEM image and method of use thereof

Also Published As

Publication number Publication date
ATE376697T1 (de) 2007-11-15
DE60223133T2 (de) 2008-08-28
US20070161044A1 (en) 2007-07-12
WO2002071336A1 (en) 2002-09-12
EP1366468B1 (de) 2007-10-24
SE0100728D0 (sv) 2001-03-05
JP2004530119A (ja) 2004-09-30
EP1366468A1 (de) 2003-12-03
DE60223133T9 (de) 2009-05-20
US20040137519A1 (en) 2004-07-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee