DE69919196D1 - Verfahren zum screening von antibakteriellen mitteln - Google Patents

Verfahren zum screening von antibakteriellen mitteln

Info

Publication number
DE69919196D1
DE69919196D1 DE69919196T DE69919196T DE69919196D1 DE 69919196 D1 DE69919196 D1 DE 69919196D1 DE 69919196 T DE69919196 T DE 69919196T DE 69919196 T DE69919196 T DE 69919196T DE 69919196 D1 DE69919196 D1 DE 69919196D1
Authority
DE
Germany
Prior art keywords
antibacterial agents
subpopulation
identified
bacteria
stationary phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69919196T
Other languages
English (en)
Other versions
DE69919196T2 (de
Inventor
Robert Coates
Yanmin Hu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helperby Therapeutics Ltd
Original Assignee
Helperby Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9824553.3A external-priority patent/GB9824553D0/en
Priority claimed from GBGB9909962.4A external-priority patent/GB9909962D0/en
Application filed by Helperby Therapeutics Ltd filed Critical Helperby Therapeutics Ltd
Publication of DE69919196D1 publication Critical patent/DE69919196D1/de
Application granted granted Critical
Publication of DE69919196T2 publication Critical patent/DE69919196T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69919196T 1998-11-09 1999-11-09 Verfahren zum screening von antibakteriellen mitteln Expired - Lifetime DE69919196T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US10765598P 1998-11-09 1998-11-09
GB9824553 1998-11-09
US107655P 1998-11-09
GBGB9824553.3A GB9824553D0 (en) 1998-11-09 1998-11-09 Improvements in or relating to screening antibacterial agents
GBGB9909962.4A GB9909962D0 (en) 1999-04-29 1999-04-29 Improvemments in or relating to screening antibacterial agents
GB9909962 1999-04-29
PCT/GB1999/003728 WO2000028074A1 (en) 1998-11-09 1999-11-09 Screening process for antibacterial agents

Publications (2)

Publication Number Publication Date
DE69919196D1 true DE69919196D1 (de) 2004-09-09
DE69919196T2 DE69919196T2 (de) 2005-08-04

Family

ID=27269546

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69919196T Expired - Lifetime DE69919196T2 (de) 1998-11-09 1999-11-09 Verfahren zum screening von antibakteriellen mitteln

Country Status (10)

Country Link
US (3) US20020031819A1 (de)
EP (1) EP1129212B1 (de)
JP (1) JP3737365B2 (de)
AT (1) ATE272717T1 (de)
AU (1) AU1061100A (de)
DE (1) DE69919196T2 (de)
DK (1) DK1129212T3 (de)
ES (1) ES2229780T3 (de)
PT (1) PT1129212E (de)
WO (1) WO2000028074A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6982153B1 (en) * 1998-12-03 2006-01-03 Targanta Therapeutics, Inc. DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides
GB0522715D0 (en) 2005-11-08 2005-12-14 Helperby Therapeutics Ltd New use
US20080220465A1 (en) * 2007-03-05 2008-09-11 Pocared Diagnostics, Inc. Antibiotic Sensitivity Testing Method
BR112012024999A2 (pt) 2010-03-30 2016-07-12 Helperby Therapeutics Ltd combinação e uso
WO2011160048A2 (en) * 2010-06-17 2011-12-22 The Johns Hopkins University Methods of identifying therapeutic agents for treating persister and bacterial infection
GB201013207D0 (en) 2010-08-05 2010-09-22 Helperby Therapeutics Ltd Novel combination
US8940723B2 (en) 2010-08-05 2015-01-27 Helperby Therapeutics Limited Combination of a pyrroloquinoline compound and a beta-lactam antimicrobial agent, mupirocin or chlorhexidine
GB201015079D0 (en) 2010-09-10 2010-10-27 Helperby Therapeutics Ltd Novel use
GB201305277D0 (en) 2013-03-22 2013-05-01 Helperby Therapeutics Ltd Novel combination and use
GB201307989D0 (en) 2013-05-02 2013-06-12 Helperby Therapeutics Ltd Novel combinations and use
GB201401617D0 (en) 2014-01-30 2014-03-19 Helperby Therapeutics Ltd Novel combination and use
JP6629327B2 (ja) 2014-12-18 2020-01-15 ヘルパービー セラピューティクス リミテッドＨｅｌｐｅｒｂｙ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ 微生物感染の予防または治療で使用される組み合わせ
CN107683136A (zh) 2015-04-11 2018-02-09 赫尔普百治疗有限公司 口腔组合物
GB201518969D0 (en) 2015-10-27 2015-12-09 Helperby Therapeutics Ltd Triple combination
GB201521771D0 (en) 2015-12-10 2016-01-27 Helperby Therapeutics Ltd Formulation
GB201610869D0 (en) 2016-06-22 2016-08-03 Helperby Therapeutics Ltd Combination
GB201612093D0 (en) 2016-07-12 2016-08-24 Helperby Therapeutics Ltd Combination
GB201616014D0 (en) 2016-09-20 2016-11-02 Helperby Therapeutics Ltd Combination
GB201616909D0 (en) 2016-10-05 2016-11-16 Helperby Therapeutics Ltd Combination
GB201703898D0 (en) 2017-03-10 2017-04-26 Helperby Therapeautics Ltd Method
GB201704620D0 (en) 2017-03-23 2017-05-10 Helperby Therapeautics Ltd Combinations
GB201709193D0 (en) 2017-06-09 2017-07-26 Helperby Therapeutics Ltd Combination
GB201807046D0 (en) 2018-04-30 2018-06-13 Helperby Therapeutics Ltd Combination
GB2589286A (en) * 2019-07-22 2021-06-02 Helperby Therapeutics Ltd Method
GB201913068D0 (en) 2019-09-10 2019-10-23 Helperby Therapeutics Ltd Combination
GB201914847D0 (en) 2019-10-14 2019-11-27 Helperby Therapeutics Ltd Combination
GB202213753D0 (en) 2022-09-20 2022-11-02 Helperby Therapeutics Ltd Antimicrobial combinations
GB202213750D0 (en) 2022-09-20 2022-11-02 Helperby Therapeutics Ltd Antimicrobial

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697648A (en) * 1968-05-24 1972-10-10 Meiji Seika Ltd Kk Antibiotic sf-767-a and sf767-l substances,and process for producing same culturing a certain streptomyces microsporeus
US3963576A (en) * 1975-02-21 1976-06-15 General Environmental Science Corporation Method for rendering bacteria dormant and the product produced thereby
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
US5670350A (en) * 1990-08-20 1997-09-23 Novartis Finance Corporation Genomic DNA encoding a pseudomonas global transcriptional activation element and its use in activating gene expression
US5684144A (en) * 1993-07-28 1997-11-04 University Of North Texas Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
US5712095A (en) * 1994-06-16 1998-01-27 Becton Dickinson And Company Rapid and sensitive detection of antibiotic-resistant mycobacteria using oligonucleotide probes specific for ribosomal RNA precursors
US5733774A (en) * 1995-02-02 1998-03-31 Ecoscience Corporation Method and composition for producing stable bacteria and bacterial formulations
US5700925A (en) * 1996-03-27 1997-12-23 The Johns Hopkins University DNA encoding stationary phase, stress response sigma factor from Mycobacterium tuberculosis
US6890526B2 (en) * 1997-05-06 2005-05-10 Vanderbilt University Methods and reagents for the treatment of multiple sclerosis
US5963576A (en) * 1997-08-04 1999-10-05 Motorola, Inc. Annular waveguide vertical cavity surface emitting laser and method of fabrication

Also Published As

Publication number Publication date
JP2002529103A (ja) 2002-09-10
JP3737365B2 (ja) 2006-01-18
ES2229780T3 (es) 2005-04-16
US20050019892A1 (en) 2005-01-27
WO2000028074A1 (en) 2000-05-18
DK1129212T3 (da) 2004-11-22
US7892782B2 (en) 2011-02-22
US20020031819A1 (en) 2002-03-14
AU1061100A (en) 2000-05-29
US20090104651A1 (en) 2009-04-23
DE69919196T2 (de) 2005-08-04
ATE272717T1 (de) 2004-08-15
PT1129212E (pt) 2004-11-30
EP1129212B1 (de) 2004-08-04
EP1129212A1 (de) 2001-09-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: STROHSCHAENK UND KOLLEGEN, 85521 OTTOBRUNN