DE60210400T2 - Die Wirkung eines Puffers auf die Säurebildung durch Plaque - Google Patents
Die Wirkung eines Puffers auf die Säurebildung durch Plaque Download PDFInfo
- Publication number
- DE60210400T2 DE60210400T2 DE60210400T DE60210400T DE60210400T2 DE 60210400 T2 DE60210400 T2 DE 60210400T2 DE 60210400 T DE60210400 T DE 60210400T DE 60210400 T DE60210400 T DE 60210400T DE 60210400 T2 DE60210400 T2 DE 60210400T2
- Authority
- DE
- Germany
- Prior art keywords
- trim
- water
- plaque
- sucrose
- minute
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 78
- 239000000203 mixture Substances 0.000 claims abstract description 14
- 238000009472 formulation Methods 0.000 claims abstract description 13
- 239000002324 mouth wash Substances 0.000 claims abstract description 9
- 229940051866 mouthwash Drugs 0.000 claims abstract description 9
- 235000013361 beverage Nutrition 0.000 claims abstract description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 39
- 229930006000 Sucrose Natural products 0.000 claims description 33
- 239000005720 sucrose Substances 0.000 claims description 33
- 230000000248 cariostatic effect Effects 0.000 claims description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 2
- 229910052697 platinum Inorganic materials 0.000 claims 1
- 208000002925 dental caries Diseases 0.000 abstract description 26
- 239000002253 acid Substances 0.000 abstract description 10
- 230000020477 pH reduction Effects 0.000 abstract description 9
- 239000000243 solution Substances 0.000 abstract description 7
- 235000011888 snacks Nutrition 0.000 abstract description 5
- 150000007513 acids Chemical class 0.000 abstract description 2
- 238000002474 experimental method Methods 0.000 description 15
- 235000000346 sugar Nutrition 0.000 description 15
- 230000004044 response Effects 0.000 description 13
- 230000001013 cariogenic effect Effects 0.000 description 12
- 230000000694 effects Effects 0.000 description 12
- 238000011534 incubation Methods 0.000 description 10
- 238000001727 in vivo Methods 0.000 description 8
- 241000194019 Streptococcus mutans Species 0.000 description 7
- 238000011282 treatment Methods 0.000 description 7
- 230000003139 buffering effect Effects 0.000 description 6
- 210000003296 saliva Anatomy 0.000 description 6
- 230000002378 acidificating effect Effects 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 208000002064 Dental Plaque Diseases 0.000 description 4
- 230000003902 lesion Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 229940112822 chewing gum Drugs 0.000 description 3
- 235000015218 chewing gum Nutrition 0.000 description 3
- 210000003298 dental enamel Anatomy 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 238000006386 neutralization reaction Methods 0.000 description 3
- 238000002601 radiography Methods 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- RMOGWMIKYWRTKW-UONOGXRCSA-N (S,S)-paclobutrazol Chemical compound C([C@@H]([C@@H](O)C(C)(C)C)N1N=CN=C1)C1=CC=C(Cl)C=C1 RMOGWMIKYWRTKW-UONOGXRCSA-N 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 244000199866 Lactobacillus casei Species 0.000 description 2
- 235000013958 Lactobacillus casei Nutrition 0.000 description 2
- 206010039424 Salivary hypersecretion Diseases 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 230000001055 chewing effect Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 229940017800 lactobacillus casei Drugs 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000011321 prophylaxis Methods 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 241001136792 Alle Species 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 241001295925 Gegenes Species 0.000 description 1
- 208000025157 Oral disease Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000000675 anti-caries Effects 0.000 description 1
- 230000000170 anti-cariogenic effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 239000004075 cariostatic agent Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 210000004489 deciduous teeth Anatomy 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 210000004268 dentin Anatomy 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000034659 glycolysis Effects 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 208000030194 mouth disease Diseases 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 208000026451 salivation Diseases 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
- A23L2/54—Mixing with gases
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/83—Electrophoresis; Electrodes; Electrolytic phenomena
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Organic Chemistry (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Non-Alcoholic Beverages (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US306970 | 1981-09-30 | ||
| US34076901P | 2001-12-11 | 2001-12-11 | |
| US340769P | 2001-12-11 | ||
| US30697002A | 2002-11-27 | 2002-11-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60210400D1 DE60210400D1 (de) | 2006-05-18 |
| DE60210400T2 true DE60210400T2 (de) | 2007-01-04 |
Family
ID=26975469
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60210400T Expired - Lifetime DE60210400T2 (de) | 2001-12-11 | 2002-12-09 | Die Wirkung eines Puffers auf die Säurebildung durch Plaque |
| DE60229310T Expired - Lifetime DE60229310D1 (de) | 2001-12-11 | 2002-12-09 | Die Wirkung eines Puffers auf die Säurebildung durch Plaque |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60229310T Expired - Lifetime DE60229310D1 (de) | 2001-12-11 | 2002-12-09 | Die Wirkung eines Puffers auf die Säurebildung durch Plaque |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1319345B1 (https=) |
| JP (1) | JP2003206232A (https=) |
| AT (2) | ATE410081T1 (https=) |
| CA (1) | CA2413844C (https=) |
| DE (2) | DE60210400T2 (https=) |
| RU (1) | RU2286137C2 (https=) |
| SG (1) | SG104350A1 (https=) |
| TW (1) | TWI231182B (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4588348B2 (ja) * | 2004-04-01 | 2010-12-01 | 昭和薬品化工株式会社 | 歯石及びウ蝕部除去剤 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1263246A1 (ru) * | 1984-01-16 | 1986-10-15 | Казанский Ордена Трудового Красного Знамени Химико-Технологический Институт Им.С.М.Кирова | Способ лечени острого стоматита |
| JP3193295B2 (ja) * | 1995-07-07 | 2001-07-30 | 株式会社日本トリム | 透析装置 |
| PT939613E (pt) * | 1996-09-18 | 2003-07-31 | Erling Johansen | Solucao sobressaturada para lavagem bucal contendo ioes calcio e fosfato |
| RU2163114C1 (ru) * | 2000-05-16 | 2001-02-20 | Торопова Анастасия Владимировна | Способ профилактики и лечения начального кариеса зубов |
-
2002
- 2002-12-06 TW TW091135412A patent/TWI231182B/zh not_active IP Right Cessation
- 2002-12-09 EP EP02258485A patent/EP1319345B1/en not_active Expired - Lifetime
- 2002-12-09 AT AT05020850T patent/ATE410081T1/de not_active IP Right Cessation
- 2002-12-09 DE DE60210400T patent/DE60210400T2/de not_active Expired - Lifetime
- 2002-12-09 DE DE60229310T patent/DE60229310D1/de not_active Expired - Lifetime
- 2002-12-09 SG SG200207471A patent/SG104350A1/en unknown
- 2002-12-09 AT AT02258485T patent/ATE322180T1/de not_active IP Right Cessation
- 2002-12-10 RU RU2002133412/15A patent/RU2286137C2/ru active
- 2002-12-10 CA CA002413844A patent/CA2413844C/en not_active Expired - Fee Related
- 2002-12-10 JP JP2002358176A patent/JP2003206232A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2413844A1 (en) | 2003-06-11 |
| DE60229310D1 (de) | 2008-11-20 |
| TWI231182B (en) | 2005-04-21 |
| DE60210400D1 (de) | 2006-05-18 |
| JP2003206232A (ja) | 2003-07-22 |
| CA2413844C (en) | 2008-02-19 |
| RU2286137C2 (ru) | 2006-10-27 |
| SG104350A1 (en) | 2004-06-21 |
| EP1319345B1 (en) | 2006-04-05 |
| TW200300694A (en) | 2003-06-16 |
| ATE322180T1 (de) | 2006-04-15 |
| ATE410081T1 (de) | 2008-10-15 |
| EP1319345A1 (en) | 2003-06-18 |
| HK1055693A1 (en) | 2004-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |