DE60206526D1 - Nicht auf affinität basierende, isotopenmarkierte peptide und verfahren zu deren anwendung - Google Patents

Nicht auf affinität basierende, isotopenmarkierte peptide und verfahren zu deren anwendung

Info

Publication number
DE60206526D1
DE60206526D1 DE60206526T DE60206526T DE60206526D1 DE 60206526 D1 DE60206526 D1 DE 60206526D1 DE 60206526 T DE60206526 T DE 60206526T DE 60206526 T DE60206526 T DE 60206526T DE 60206526 D1 DE60206526 D1 DE 60206526D1
Authority
DE
Germany
Prior art keywords
peptides
isotope
anchoring
tag
affinity based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60206526T
Other languages
English (en)
Other versions
DE60206526T2 (de
Inventor
P Gygi
Anthony Gerber
Augusto Gartner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard College
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Application granted granted Critical
Publication of DE60206526D1 publication Critical patent/DE60206526D1/de
Publication of DE60206526T2 publication Critical patent/DE60206526T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60206526T 2001-07-16 2002-07-16 Nicht auf affinität basierende, isotopenmarkierte peptide und verfahren zu deren anwendung Expired - Lifetime DE60206526T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30580801P 2001-07-16 2001-07-16
US305808P 2001-07-16
PCT/US2002/022598 WO2003008547A2 (en) 2001-07-16 2002-07-16 Non-affinity based isotope tagged peptides and methods for using the same

Publications (2)

Publication Number Publication Date
DE60206526D1 true DE60206526D1 (de) 2006-02-16
DE60206526T2 DE60206526T2 (de) 2006-07-13

Family

ID=23182434

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60206526T Expired - Lifetime DE60206526T2 (de) 2001-07-16 2002-07-16 Nicht auf affinität basierende, isotopenmarkierte peptide und verfahren zu deren anwendung

Country Status (5)

Country Link
EP (1) EP1456227B1 (de)
AT (1) ATE305938T1 (de)
AU (1) AU2002322506A1 (de)
DE (1) DE60206526T2 (de)
WO (1) WO2003008547A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2857451B1 (fr) * 2003-07-11 2005-09-30 Commissariat Energie Atomique Procede et dispositif pour l'analyse de milieux reactionnels vivants
WO2005012247A1 (en) * 2003-07-30 2005-02-10 Hôpital Sainte-Justine Compounds and methods for the rapid quantitative analysis of proteins and polypeptides
US20050074824A1 (en) * 2003-08-22 2005-04-07 Martyn Botfield Quantification and site-specific profiling of protein phosphorylation
US7569392B2 (en) 2004-01-08 2009-08-04 Vanderbilt University Multiplex spatial profiling of gene expression
CN1304845C (zh) * 2004-04-14 2007-03-14 中国科学院上海有机化学研究所 一种新型含碘树脂衍生物用在基于质谱的蛋白组学研究中的方法
US20090053817A1 (en) * 2004-08-16 2009-02-26 Ludwig Institute For Cancer Research Fixed charge reagents
EP1797433A1 (de) * 2004-09-29 2007-06-20 University Of Florida Research Foundation, Inc. Mit isotopen markierte dinitrophenylhydrazine und verwendungsverfahren dafür
FR2894827B1 (fr) 2005-12-21 2010-10-29 Galderma Res & Dev Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation,et leurs utilisations
EP1921081A1 (de) 2006-11-06 2008-05-14 Koninklijke Philips Electronics N.V. Verwendung von Arylboronsäuren zur Proteinmarkierung
FR3049346B1 (fr) 2016-03-23 2024-05-17 Anaquant Billes solubles pour la preparation de solutions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4594111A (en) * 1984-10-04 1986-06-10 Coonan Edmund C Liquid phase cleaner-solvent
US6670194B1 (en) * 1998-08-25 2003-12-30 University Of Washington Rapid quantitative analysis of proteins or protein function in complex mixtures

Also Published As

Publication number Publication date
DE60206526T2 (de) 2006-07-13
ATE305938T1 (de) 2005-10-15
WO2003008547A2 (en) 2003-01-30
AU2002322506A1 (en) 2003-03-03
EP1456227A4 (de) 2004-12-15
WO2003008547A3 (en) 2003-12-04
EP1456227B1 (de) 2005-10-05
EP1456227A2 (de) 2004-09-15

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