DE60203818D1 - Benzotriazepine als gastrin und cholecystokinin rezeptor liganden - Google Patents
Benzotriazepine als gastrin und cholecystokinin rezeptor ligandenInfo
- Publication number
- DE60203818D1 DE60203818D1 DE60203818T DE60203818T DE60203818D1 DE 60203818 D1 DE60203818 D1 DE 60203818D1 DE 60203818 T DE60203818 T DE 60203818T DE 60203818 T DE60203818 T DE 60203818T DE 60203818 D1 DE60203818 D1 DE 60203818D1
- Authority
- DE
- Germany
- Prior art keywords
- cholecystokinine
- benzotriazepine
- liganden
- gastrin
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0127262 | 2001-11-13 | ||
GB0127262A GB0127262D0 (en) | 2001-11-13 | 2001-11-13 | Gastrin and cholecystokinin receptor ligands (VI) |
GB0219051A GB0219051D0 (en) | 2002-08-15 | 2002-08-15 | Gastrin and cholecystokinin receptor ligands (V1-2) |
GB0219051 | 2002-08-15 | ||
PCT/GB2002/005121 WO2003041714A1 (en) | 2001-11-13 | 2002-11-12 | Benzotriazepines as gastrin and cholecystokinin receptor ligands |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60203818D1 true DE60203818D1 (de) | 2005-05-25 |
DE60203818T2 DE60203818T2 (de) | 2006-01-26 |
Family
ID=26246762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60203818T Expired - Fee Related DE60203818T2 (de) | 2001-11-13 | 2002-11-12 | Benzotriazepine als gastrin und cholecystokinin rezeptor liganden |
Country Status (20)
Country | Link |
---|---|
US (1) | US20060003993A1 (de) |
EP (1) | EP1443934B1 (de) |
JP (1) | JP2005513013A (de) |
KR (1) | KR20050044852A (de) |
CN (1) | CN100348196C (de) |
AR (1) | AR037359A1 (de) |
AT (1) | ATE293449T1 (de) |
BR (1) | BR0213317A (de) |
CA (1) | CA2466955A1 (de) |
DE (1) | DE60203818T2 (de) |
ES (1) | ES2240815T3 (de) |
HU (1) | HUP0402068A3 (de) |
IL (1) | IL161330A0 (de) |
MX (1) | MXPA04003544A (de) |
NO (1) | NO20042452L (de) |
NZ (1) | NZ532213A (de) |
PL (1) | PL369568A1 (de) |
RU (1) | RU2304438C2 (de) |
TW (1) | TW200303205A (de) |
WO (1) | WO2003041714A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004101533A1 (en) * | 2003-05-12 | 2004-11-25 | Janssen Pharmaceutica, N.V. | 1, 3, 4-benzotriazepin-2-one salts and their use as cck receptor ligands |
US20050043359A1 (en) * | 2003-08-20 | 2005-02-24 | The Procter & Gamble Company | Kit for treatment of upper gastrointestinal tract conditions |
WO2005074931A1 (en) * | 2004-01-28 | 2005-08-18 | Altana Pharma Ag | Pharmaceutical combinations comprising (s) -pantoprazole |
GB0425196D0 (en) * | 2004-11-15 | 2004-12-15 | Black James Foundation | Gastrin and cholecystokinin receptor ligands |
ES2442865T3 (es) * | 2005-09-16 | 2014-02-14 | Janssen Pharmaceutica N.V. | Procedimiento para la preparación de derivados de venzo[E][1,2,4]triazepina-2-ona |
GB0610018D0 (en) * | 2006-05-19 | 2006-06-28 | James Black Foundation | Benzotriazepinone derivatives |
WO2007135417A1 (en) * | 2006-05-19 | 2007-11-29 | James Black Foundation | Benzotriazepinone derivatives |
US7863330B2 (en) | 2006-06-14 | 2011-01-04 | Rottapharm S.P.A. | Deloxiglumide and proton pump inhibitor combination in the treatment of gastrointestinal disorders |
PL3071206T3 (pl) | 2013-11-22 | 2022-01-17 | CL BioSciences LLC | Antagoniści gastryny (eg yf476, netazepid) do leczenia i zapobiegania osteoporozie |
GB201414116D0 (en) | 2014-08-08 | 2014-09-24 | Trio Medicines Ltd | Benzodiazepine derivatives |
GB201513979D0 (en) | 2015-08-07 | 2015-09-23 | Trio Medicines Ltd | Synthesis of benzodiazepine derivatives |
US11097031B2 (en) | 2016-08-01 | 2021-08-24 | The Procter & Gamble Company | Phase-stable, sprayable freshening compositions comprising suspended particles |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3176008A (en) * | 1962-09-11 | 1965-03-30 | American Home Prod | 5-phenyl-benzotriazepin-2-one compounds and their production |
US5091381A (en) * | 1991-04-12 | 1992-02-25 | Biomeasure, Inc. | 2H-1,3,4-benzotriazepin-2-ones |
AU3247593A (en) * | 1991-12-20 | 1993-07-28 | Warner-Lambert Company | Therapeutic combinations useful in the treatment of gastroesophageal reflux disease |
US5378838A (en) * | 1993-01-13 | 1995-01-03 | Merck & Co., Inc. | Benzodiazepine cholecystokinin antagonists |
-
2002
- 2002-11-12 US US10/495,464 patent/US20060003993A1/en not_active Abandoned
- 2002-11-12 RU RU2004117880/15A patent/RU2304438C2/ru not_active IP Right Cessation
- 2002-11-12 HU HU0402068A patent/HUP0402068A3/hu unknown
- 2002-11-12 IL IL16133002A patent/IL161330A0/xx unknown
- 2002-11-12 ES ES02775003T patent/ES2240815T3/es not_active Expired - Lifetime
- 2002-11-12 WO PCT/GB2002/005121 patent/WO2003041714A1/en active IP Right Grant
- 2002-11-12 BR BR0213317-2A patent/BR0213317A/pt not_active Application Discontinuation
- 2002-11-12 MX MXPA04003544A patent/MXPA04003544A/es unknown
- 2002-11-12 CN CNB028223403A patent/CN100348196C/zh not_active Expired - Fee Related
- 2002-11-12 CA CA002466955A patent/CA2466955A1/en not_active Abandoned
- 2002-11-12 JP JP2003543601A patent/JP2005513013A/ja active Pending
- 2002-11-12 NZ NZ532213A patent/NZ532213A/en unknown
- 2002-11-12 AT AT02775003T patent/ATE293449T1/de not_active IP Right Cessation
- 2002-11-12 KR KR1020047007006A patent/KR20050044852A/ko not_active Application Discontinuation
- 2002-11-12 EP EP02775003A patent/EP1443934B1/de not_active Expired - Lifetime
- 2002-11-12 DE DE60203818T patent/DE60203818T2/de not_active Expired - Fee Related
- 2002-11-12 PL PL02369568A patent/PL369568A1/xx not_active Application Discontinuation
- 2002-11-13 TW TW091133267A patent/TW200303205A/zh unknown
- 2002-11-13 AR ARP020104345A patent/AR037359A1/es unknown
-
2004
- 2004-06-11 NO NO20042452A patent/NO20042452L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2003041714A1 (en) | 2003-05-22 |
BR0213317A (pt) | 2004-10-13 |
EP1443934B1 (de) | 2005-04-20 |
MXPA04003544A (es) | 2004-07-22 |
CN1585643A (zh) | 2005-02-23 |
US20060003993A1 (en) | 2006-01-05 |
AU2002341218B2 (en) | 2007-03-15 |
TW200303205A (en) | 2003-09-01 |
RU2004117880A (ru) | 2005-04-20 |
HUP0402068A2 (hu) | 2005-02-28 |
HUP0402068A3 (en) | 2005-09-28 |
RU2304438C2 (ru) | 2007-08-20 |
KR20050044852A (ko) | 2005-05-13 |
AR037359A1 (es) | 2004-11-03 |
IL161330A0 (en) | 2004-09-27 |
ATE293449T1 (de) | 2005-05-15 |
CN100348196C (zh) | 2007-11-14 |
EP1443934A1 (de) | 2004-08-11 |
CA2466955A1 (en) | 2003-05-22 |
NO20042452L (no) | 2004-08-12 |
JP2005513013A (ja) | 2005-05-12 |
NZ532213A (en) | 2006-12-22 |
PL369568A1 (en) | 2005-05-02 |
DE60203818T2 (de) | 2006-01-26 |
ES2240815T3 (es) | 2005-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: WITTE, WELLER & PARTNER, 70178 STUTTGART |
|
8339 | Ceased/non-payment of the annual fee |