ATE293449T1 - Benzotriazepine als gastrin und cholecystokinin rezeptor liganden - Google Patents

Benzotriazepine als gastrin und cholecystokinin rezeptor liganden

Info

Publication number
ATE293449T1
ATE293449T1 AT02775003T AT02775003T ATE293449T1 AT E293449 T1 ATE293449 T1 AT E293449T1 AT 02775003 T AT02775003 T AT 02775003T AT 02775003 T AT02775003 T AT 02775003T AT E293449 T1 ATE293449 T1 AT E293449T1
Authority
AT
Austria
Prior art keywords
benzotriazepines
gastrin
receptor ligands
cholecystokinin receptor
cholecystokinin
Prior art date
Application number
AT02775003T
Other languages
English (en)
Inventor
Iain Mair Mcdonald
Ildiko Maria Buck
Elaine Anne Harper
Ian Duncan Linney
Michael John Pether
Katherine Isobel Mary Steel
Carol Austin
David John Dunstone
Sarkis Barret Kalindjian
Caroline Minli Rachel Low
John Spencer
Paul Trevor Wright
Original Assignee
Black James Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0127262A external-priority patent/GB0127262D0/en
Priority claimed from GB0219051A external-priority patent/GB0219051D0/en
Application filed by Black James Foundation filed Critical Black James Foundation
Application granted granted Critical
Publication of ATE293449T1 publication Critical patent/ATE293449T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02775003T 2001-11-13 2002-11-12 Benzotriazepine als gastrin und cholecystokinin rezeptor liganden ATE293449T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0127262A GB0127262D0 (en) 2001-11-13 2001-11-13 Gastrin and cholecystokinin receptor ligands (VI)
GB0219051A GB0219051D0 (en) 2002-08-15 2002-08-15 Gastrin and cholecystokinin receptor ligands (V1-2)
PCT/GB2002/005121 WO2003041714A1 (en) 2001-11-13 2002-11-12 Benzotriazepines as gastrin and cholecystokinin receptor ligands

Publications (1)

Publication Number Publication Date
ATE293449T1 true ATE293449T1 (de) 2005-05-15

Family

ID=26246762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02775003T ATE293449T1 (de) 2001-11-13 2002-11-12 Benzotriazepine als gastrin und cholecystokinin rezeptor liganden

Country Status (20)

Country Link
US (1) US20060003993A1 (de)
EP (1) EP1443934B1 (de)
JP (1) JP2005513013A (de)
KR (1) KR20050044852A (de)
CN (1) CN100348196C (de)
AR (1) AR037359A1 (de)
AT (1) ATE293449T1 (de)
BR (1) BR0213317A (de)
CA (1) CA2466955A1 (de)
DE (1) DE60203818T2 (de)
ES (1) ES2240815T3 (de)
HU (1) HUP0402068A3 (de)
IL (1) IL161330A0 (de)
MX (1) MXPA04003544A (de)
NO (1) NO20042452L (de)
NZ (1) NZ532213A (de)
PL (1) PL369568A1 (de)
RU (1) RU2304438C2 (de)
TW (1) TW200303205A (de)
WO (1) WO2003041714A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004101533A1 (en) * 2003-05-12 2004-11-25 Janssen Pharmaceutica, N.V. 1, 3, 4-benzotriazepin-2-one salts and their use as cck receptor ligands
US20050043359A1 (en) * 2003-08-20 2005-02-24 The Procter & Gamble Company Kit for treatment of upper gastrointestinal tract conditions
WO2005074931A1 (en) * 2004-01-28 2005-08-18 Altana Pharma Ag Pharmaceutical combinations comprising (s) -pantoprazole
GB0425196D0 (en) * 2004-11-15 2004-12-15 Black James Foundation Gastrin and cholecystokinin receptor ligands
ES2442865T3 (es) * 2005-09-16 2014-02-14 Janssen Pharmaceutica N.V. Procedimiento para la preparación de derivados de venzo[E][1,2,4]triazepina-2-ona
GB0610018D0 (en) * 2006-05-19 2006-06-28 James Black Foundation Benzotriazepinone derivatives
WO2007135417A1 (en) * 2006-05-19 2007-11-29 James Black Foundation Benzotriazepinone derivatives
US7863330B2 (en) 2006-06-14 2011-01-04 Rottapharm S.P.A. Deloxiglumide and proton pump inhibitor combination in the treatment of gastrointestinal disorders
PL3071206T3 (pl) 2013-11-22 2022-01-17 CL BioSciences LLC Antagoniści gastryny (eg yf476, netazepid) do leczenia i zapobiegania osteoporozie
GB201414116D0 (en) 2014-08-08 2014-09-24 Trio Medicines Ltd Benzodiazepine derivatives
GB201513979D0 (en) 2015-08-07 2015-09-23 Trio Medicines Ltd Synthesis of benzodiazepine derivatives
US11097031B2 (en) 2016-08-01 2021-08-24 The Procter & Gamble Company Phase-stable, sprayable freshening compositions comprising suspended particles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3176008A (en) * 1962-09-11 1965-03-30 American Home Prod 5-phenyl-benzotriazepin-2-one compounds and their production
US5091381A (en) * 1991-04-12 1992-02-25 Biomeasure, Inc. 2H-1,3,4-benzotriazepin-2-ones
AU3247593A (en) * 1991-12-20 1993-07-28 Warner-Lambert Company Therapeutic combinations useful in the treatment of gastroesophageal reflux disease
US5378838A (en) * 1993-01-13 1995-01-03 Merck & Co., Inc. Benzodiazepine cholecystokinin antagonists

Also Published As

Publication number Publication date
WO2003041714A1 (en) 2003-05-22
BR0213317A (pt) 2004-10-13
EP1443934B1 (de) 2005-04-20
MXPA04003544A (es) 2004-07-22
CN1585643A (zh) 2005-02-23
US20060003993A1 (en) 2006-01-05
AU2002341218B2 (en) 2007-03-15
TW200303205A (en) 2003-09-01
RU2004117880A (ru) 2005-04-20
HUP0402068A2 (hu) 2005-02-28
DE60203818D1 (de) 2005-05-25
HUP0402068A3 (en) 2005-09-28
RU2304438C2 (ru) 2007-08-20
KR20050044852A (ko) 2005-05-13
AR037359A1 (es) 2004-11-03
IL161330A0 (en) 2004-09-27
CN100348196C (zh) 2007-11-14
EP1443934A1 (de) 2004-08-11
CA2466955A1 (en) 2003-05-22
NO20042452L (no) 2004-08-12
JP2005513013A (ja) 2005-05-12
NZ532213A (en) 2006-12-22
PL369568A1 (en) 2005-05-02
DE60203818T2 (de) 2006-01-26
ES2240815T3 (es) 2005-10-16

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Legal Events

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