DE60201837D1 - Synergistiche zusammensetzungen von n-acylhomoserinlaktonen und 4-chinolinonen - Google Patents

Synergistiche zusammensetzungen von n-acylhomoserinlaktonen und 4-chinolinonen

Info

Publication number
DE60201837D1
DE60201837D1 DE60201837T DE60201837T DE60201837D1 DE 60201837 D1 DE60201837 D1 DE 60201837D1 DE 60201837 T DE60201837 T DE 60201837T DE 60201837 T DE60201837 T DE 60201837T DE 60201837 D1 DE60201837 D1 DE 60201837D1
Authority
DE
Germany
Prior art keywords
sup
sub
halo
alkyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60201837T
Other languages
English (en)
Other versions
DE60201837T2 (de
Inventor
David I Pritchard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Secretary Of State For Defence vertreten Durch
Original Assignee
University of Nottingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Nottingham filed Critical University of Nottingham
Application granted granted Critical
Publication of DE60201837D1 publication Critical patent/DE60201837D1/de
Publication of DE60201837T2 publication Critical patent/DE60201837T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60201837T 2001-07-04 2002-07-03 Synergistische zusammensetzungen von n-acylhomoserinlaktonen und 4-chinolinonen Expired - Fee Related DE60201837T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0116312.0A GB0116312D0 (en) 2001-07-04 2001-07-04 "Compositions containing N-acyl homoserine lactones"
GB0116312 2001-07-04
PCT/GB2002/003071 WO2003004017A1 (en) 2001-07-04 2002-07-03 Synergistic compositions of n-acylhomoserine lactones and 4-quinolones

Publications (2)

Publication Number Publication Date
DE60201837D1 true DE60201837D1 (de) 2004-12-09
DE60201837T2 DE60201837T2 (de) 2005-10-27

Family

ID=9917890

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60201837T Expired - Fee Related DE60201837T2 (de) 2001-07-04 2002-07-03 Synergistische zusammensetzungen von n-acylhomoserinlaktonen und 4-chinolinonen

Country Status (6)

Country Link
US (1) US7371779B2 (de)
EP (1) EP1404315B1 (de)
AT (1) ATE281163T1 (de)
DE (1) DE60201837T2 (de)
GB (1) GB0116312D0 (de)
WO (1) WO2003004017A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1051115C (zh) * 1996-05-22 2000-04-05 天津纺织工学院 调温纤维及其制品
GB0116312D0 (en) 2001-07-04 2001-08-29 Univ Nottingham "Compositions containing N-acyl homoserine lactones"
US7338969B2 (en) 2002-03-08 2008-03-04 Quonova, Llc Modulation of pathogenicity
US7335779B2 (en) 2002-03-08 2008-02-26 Quonova, Llc Modulation of pathogenicity
EP1782826A1 (de) * 2005-11-08 2007-05-09 GBF Gesellschaft für Biotechnologische Forschung mbH PQS, c-di-GMP und deren Konjugate als Ajuvans und deren Verwendung in Pharmazeutische Zusammensetzungen
EP2078713A1 (de) 2007-12-28 2009-07-15 QuoNova GmbH Hemmer der Biofilmbildung grampositiver und gramnegativer Bakterien
JP5816618B2 (ja) * 2009-07-03 2015-11-18 ザ ナショナル インスティテュート フォー バイオテクノロジー イン ザ ネゲヴ リミテッドＴｈｅ Ｎａｔｉｏｎａｌ Ｉｎｓｔｉｔｕｔｅ Ｆｏｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｉｎ Ｔｈｅ Ｎｅｇｅｖ Ｌｔｄ． 細菌のクオラムセンシングの共有結合阻害
CN108884049A (zh) 2016-02-09 2018-11-23 法玛克亚公司 喹啉酮赖氨酰氧化酶样2抑制剂及其用途
CN114805049A (zh) * 2022-04-18 2022-07-29 深圳深信生物科技有限公司 一种10-氧代十九烷二酸的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE184194T1 (de) 1993-07-02 1999-09-15 Univ Nottingham Immunsuppressive und antiallergische verbindungen; z.b. n-(3-oxohexanoyl)- homoserinlacton
GB0007588D0 (en) 2000-03-30 2000-05-17 Univ Nottingham N-Acyl homoserine lactones
GB0030729D0 (en) * 2000-12-16 2001-01-31 Univ Nottingham Substituted-4-Quinolones
GB0116312D0 (en) 2001-07-04 2001-08-29 Univ Nottingham "Compositions containing N-acyl homoserine lactones"

Also Published As

Publication number Publication date
ATE281163T1 (de) 2004-11-15
DE60201837T2 (de) 2005-10-27
US7371779B2 (en) 2008-05-13
GB0116312D0 (en) 2001-08-29
EP1404315A1 (de) 2004-04-07
US20040198978A1 (en) 2004-10-07
WO2003004017A1 (en) 2003-01-16
EP1404315B1 (de) 2004-11-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: THE SECRETARY OF STATE FOR DEFENCE,VERTRETEN DURCH

8339 Ceased/non-payment of the annual fee