DE602007008526D1 - Phenylalanin-verbindung oder eines salzes oder esters davon - Google Patents
Phenylalanin-verbindung oder eines salzes oder esters davonInfo
- Publication number
- DE602007008526D1 DE602007008526D1 DE602007008526T DE602007008526T DE602007008526D1 DE 602007008526 D1 DE602007008526 D1 DE 602007008526D1 DE 602007008526 T DE602007008526 T DE 602007008526T DE 602007008526 T DE602007008526 T DE 602007008526T DE 602007008526 D1 DE602007008526 D1 DE 602007008526D1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- compound represented
- salt
- esters
- optically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006009002 | 2006-01-17 | ||
PCT/JP2007/050851 WO2007083776A1 (ja) | 2006-01-17 | 2007-01-15 | 光学活性ビフェニルアラニン化合物またはその塩およびそのエステルの製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007008526D1 true DE602007008526D1 (de) | 2010-09-30 |
Family
ID=38287725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007008526T Active DE602007008526D1 (de) | 2006-01-17 | 2007-01-15 | Phenylalanin-verbindung oder eines salzes oder esters davon |
Country Status (6)
Country | Link |
---|---|
US (1) | US8017378B2 (de) |
EP (1) | EP1980622B1 (de) |
CN (1) | CN101370943B (de) |
AT (1) | ATE478154T1 (de) |
DE (1) | DE602007008526D1 (de) |
WO (1) | WO2007083776A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008120567A1 (ja) * | 2007-03-20 | 2008-10-09 | Sumitomo Chemical Company, Limited | L-ビフェニルアラニン化合物の塩の回収方法、およびそれを用いたビフェニルアラニンエステル化合物の回収方法 |
KR101034709B1 (ko) | 2009-12-14 | 2011-05-17 | 삼성에스디아이 주식회사 | 이차전지 |
EP2744779A1 (de) | 2011-08-19 | 2014-06-25 | DSM IP Assets B.V. | Synthese von r-biphenylalaninol |
AU2012326361B2 (en) | 2011-10-17 | 2017-08-03 | Biotheryx, Inc. | Substituted biaryl alkyl amides |
CN104725256B (zh) * | 2015-02-11 | 2018-03-16 | 威海迪素制药有限公司 | 一种联苯丙氨酸衍生物的制备方法 |
CN104725279B (zh) * | 2015-02-12 | 2018-03-02 | 威海迪素制药有限公司 | 一种N‑Boc‑联苯丙氨酸衍生物的制备方法 |
CN106467471B (zh) * | 2015-08-18 | 2021-02-02 | 上海翰森生物医药科技有限公司 | 一种高光学纯度联苯基丙氨酸及其衍生物的制备方法和应用 |
CN105585511B (zh) * | 2016-01-08 | 2017-05-31 | 浙江大学 | (r)‑n‑叔丁氧羰基联苯丙氨醇的制备方法 |
KR20170119447A (ko) | 2016-04-19 | 2017-10-27 | 주식회사 아미노로직스 | Dl-4,4'-바이페닐알라닌 알킬에스터로부터 d-4,4'-바이페닐알라닌 알킬에스터 또는 l-4,4'-바이페닐알라닌 알킬에스터를 제조하는 방법 |
CN106399412B (zh) * | 2016-06-03 | 2019-12-10 | 南京红杉生物科技有限公司 | 合成d-联苯基丙氨酸的方法 |
US20190256454A1 (en) | 2016-07-05 | 2019-08-22 | Novartis Ag | New process for early sacubitril intermediates |
WO2018033866A1 (en) | 2016-08-17 | 2018-02-22 | Novartis Ag | New processes and intermediates for nep inhibitor synthesis |
WO2018116203A1 (en) | 2016-12-23 | 2018-06-28 | Novartis Ag | New process for early sacubitril intermediates |
CN108675943A (zh) * | 2018-06-13 | 2018-10-19 | 常州亚邦制药有限公司 | 一种沙库巴曲关键中间体的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4262092A (en) * | 1979-05-08 | 1981-04-14 | Ethyl Corporation | Process for producing N-acyl-D-phenylalanine ester |
US5294632A (en) * | 1991-05-01 | 1994-03-15 | Ciba-Geigy Corporation | Phosphono/biaryl substituted dipetide derivatives |
JP3160879B2 (ja) | 1996-01-30 | 2001-04-25 | 田辺製薬株式会社 | 光学活性アミノ酸誘導体の製法 |
JP4270484B2 (ja) | 2002-03-08 | 2009-06-03 | 第一ファインケミカル株式会社 | 光学活性フェニルアラニン誘導体の製造方法 |
KR100654587B1 (ko) * | 2002-12-18 | 2006-12-07 | 주식회사 엘지생명과학 | 효소를 이용한 (r)- 또는(s)-n-(2,6-디메틸페닐)알라닌과 그것의 대응 에스테르화합물의 입체이성질체의 제조방법 |
-
2007
- 2007-01-15 EP EP07713656A patent/EP1980622B1/de not_active Not-in-force
- 2007-01-15 US US12/087,753 patent/US8017378B2/en not_active Expired - Fee Related
- 2007-01-15 AT AT07713656T patent/ATE478154T1/de not_active IP Right Cessation
- 2007-01-15 DE DE602007008526T patent/DE602007008526D1/de active Active
- 2007-01-15 WO PCT/JP2007/050851 patent/WO2007083776A1/ja active Application Filing
- 2007-01-15 CN CN2007800023196A patent/CN101370943B/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1980622A4 (de) | 2009-10-21 |
ATE478154T1 (de) | 2010-09-15 |
US8017378B2 (en) | 2011-09-13 |
WO2007083776A1 (ja) | 2007-07-26 |
US20090011475A1 (en) | 2009-01-08 |
CN101370943A (zh) | 2009-02-18 |
EP1980622A1 (de) | 2008-10-15 |
EP1980622B1 (de) | 2010-08-18 |
CN101370943B (zh) | 2012-02-15 |
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