DE602006018308D1 - Chimärer impfstoff für haemophilus influenzae-induzierte infektion - Google Patents
Chimärer impfstoff für haemophilus influenzae-induzierte infektionInfo
- Publication number
- DE602006018308D1 DE602006018308D1 DE602006018308T DE602006018308T DE602006018308D1 DE 602006018308 D1 DE602006018308 D1 DE 602006018308D1 DE 602006018308 T DE602006018308 T DE 602006018308T DE 602006018308 T DE602006018308 T DE 602006018308T DE 602006018308 D1 DE602006018308 D1 DE 602006018308D1
- Authority
- DE
- Germany
- Prior art keywords
- haemophilus influenzae
- protein
- chimeric vaccine
- induced infection
- nthi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1242—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69764205P | 2005-07-08 | 2005-07-08 | |
US80183506P | 2006-05-19 | 2006-05-19 | |
PCT/US2006/026183 WO2007008527A2 (en) | 2005-07-08 | 2006-07-05 | Chimeric vaccine for haemophilus influenzae-induced disease |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006018308D1 true DE602006018308D1 (de) | 2010-12-30 |
Family
ID=37441871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006018308T Active DE602006018308D1 (de) | 2005-07-08 | 2006-07-05 | Chimärer impfstoff für haemophilus influenzae-induzierte infektion |
Country Status (7)
Country | Link |
---|---|
US (3) | US7811591B2 (de) |
EP (2) | EP1904519B1 (de) |
JP (2) | JP2009500037A (de) |
AT (1) | ATE488526T1 (de) |
CA (1) | CA2613970C (de) |
DE (1) | DE602006018308D1 (de) |
WO (1) | WO2007008527A2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9812613D0 (en) * | 1998-06-11 | 1998-08-12 | Smithkline Beecham Biolog | Vaccine |
US7811591B2 (en) * | 2005-07-08 | 2010-10-12 | Nationwide Children's Hospital, Inc. | Chimeric vaccine for haemophilus influenzae-induced disease |
TW201302779A (zh) * | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
CN104968366B (zh) * | 2012-10-17 | 2017-12-01 | 葛兰素史密丝克莱恩生物有限公司 | 包含一种或多种肺炎链球菌荚膜糖缀合物和含有来自流感嗜血杆菌的蛋白E和/或PilA的蛋白组分的免疫原性组合物 |
GB201218660D0 (en) | 2012-10-17 | 2012-11-28 | Glaxosmithkline Biolog Sa | Immunogenic composition |
AU2014225330B2 (en) | 2013-03-08 | 2018-11-01 | Lauren O. Bakaletz | Transcutaneous dosage formulation |
US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
US20180207067A1 (en) | 2015-07-14 | 2018-07-26 | Research Institute at Nationwide Children's Hospit al | Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity |
JP2018528763A (ja) | 2015-07-31 | 2018-10-04 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | バイオフィルムの除去のためのペプチドおよび抗体 |
EP3365027B1 (de) | 2015-10-14 | 2022-03-30 | Research Institute at Nationwide Children's Hospital | Hu-spezifische antikörper und deren verwendeng zur hemmung von biofilm |
CA3049105A1 (en) | 2017-01-04 | 2018-07-12 | Lauren O. Bakaletz | Dnabii vaccines and antibodies with enhanced activity |
CN112851812B (zh) * | 2020-06-30 | 2021-09-14 | 广州百暨基因科技有限公司 | 抗b7h3抗体及其应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US19005A (en) | 1857-12-29 | de witt | ||
US697642A (en) | 1901-03-09 | 1902-04-15 | Liberty Millet | Process of strengthening clay hydraulic pipe, vases, crockery-ware, &c. |
US801835A (en) | 1905-02-25 | 1905-10-17 | Rudolph H Apelt | Ball-bearing. |
US1900504A (en) | 1930-11-25 | 1933-03-07 | Ingersoll Rand Co | Condensing apparatus |
DE69431624T2 (de) * | 1993-05-18 | 2003-07-10 | Univ Ohio State Res Found | Impfstoff gegen mittelohrentzündung |
DE4336530C1 (de) * | 1993-10-26 | 1995-04-13 | Max Planck Gesellschaft | Rekombinante PilC-Proteine, Verfahren zu ihrer Herstellung und ihre Verwendung |
US6355450B1 (en) * | 1995-04-21 | 2002-03-12 | Human Genome Sciences, Inc. | Computer readable genomic sequence of Haemophilus influenzae Rd, fragments thereof, and uses thereof |
US5843464A (en) * | 1995-06-02 | 1998-12-01 | The Ohio State University | Synthetic chimeric fimbrin peptides |
GB9812613D0 (en) * | 1998-06-11 | 1998-08-12 | Smithkline Beecham Biolog | Vaccine |
PT2192127E (pt) * | 2003-12-23 | 2012-08-06 | Nationwide Children S Hospital Inc | Pili de tipo iv de haemophilus influenzae |
US7811591B2 (en) * | 2005-07-08 | 2010-10-12 | Nationwide Children's Hospital, Inc. | Chimeric vaccine for haemophilus influenzae-induced disease |
-
2006
- 2006-07-05 US US11/994,830 patent/US7811591B2/en active Active
- 2006-07-05 DE DE602006018308T patent/DE602006018308D1/de active Active
- 2006-07-05 EP EP06800001A patent/EP1904519B1/de not_active Not-in-force
- 2006-07-05 EP EP10174620A patent/EP2298794A3/de not_active Withdrawn
- 2006-07-05 CA CA2613970A patent/CA2613970C/en not_active Expired - Fee Related
- 2006-07-05 JP JP2008520357A patent/JP2009500037A/ja active Pending
- 2006-07-05 WO PCT/US2006/026183 patent/WO2007008527A2/en active Application Filing
- 2006-07-05 AT AT06800001T patent/ATE488526T1/de not_active IP Right Cessation
-
2009
- 2009-10-14 JP JP2009237768A patent/JP2010172332A/ja active Pending
-
2010
- 2010-10-05 US US12/898,287 patent/US8263363B2/en active Active
-
2012
- 2012-09-10 US US13/608,500 patent/US8741304B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20130064828A1 (en) | 2013-03-14 |
EP2298794A2 (de) | 2011-03-23 |
EP1904519A2 (de) | 2008-04-02 |
JP2010172332A (ja) | 2010-08-12 |
US8741304B2 (en) | 2014-06-03 |
WO2007008527A2 (en) | 2007-01-18 |
EP1904519B1 (de) | 2010-11-17 |
EP2298794A3 (de) | 2011-04-06 |
ATE488526T1 (de) | 2010-12-15 |
US20080311110A1 (en) | 2008-12-18 |
WO2007008527A3 (en) | 2007-03-15 |
CA2613970C (en) | 2015-12-08 |
US8263363B2 (en) | 2012-09-11 |
US20110081357A1 (en) | 2011-04-07 |
US7811591B2 (en) | 2010-10-12 |
JP2009500037A (ja) | 2009-01-08 |
CA2613970A1 (en) | 2007-01-18 |
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