ATE370745T1 - Verbesserte polysaccharid- und glykokonjugat- vakzine - Google Patents
Verbesserte polysaccharid- und glykokonjugat- vakzineInfo
- Publication number
- ATE370745T1 ATE370745T1 AT03749887T AT03749887T ATE370745T1 AT E370745 T1 ATE370745 T1 AT E370745T1 AT 03749887 T AT03749887 T AT 03749887T AT 03749887 T AT03749887 T AT 03749887T AT E370745 T1 ATE370745 T1 AT E370745T1
- Authority
- AT
- Austria
- Prior art keywords
- glycoconjugate vaccines
- polysaccharide
- improved polysaccharide
- improved
- polyfunctional
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/10—Peptides being immobilised on, or in, an organic carrier the carrier being a carbohydrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Sustainable Development (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IT2002/000307 WO2003094961A1 (en) | 2002-05-09 | 2002-05-09 | Improved polysaccharide and glycoconjugate vaccines_____________ |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE370745T1 true ATE370745T1 (de) | 2007-09-15 |
Family
ID=29415984
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03749887T ATE370745T1 (de) | 2002-05-09 | 2003-05-07 | Verbesserte polysaccharid- und glykokonjugat- vakzine |
Country Status (8)
Country | Link |
---|---|
US (1) | US7588765B2 (de) |
EP (1) | EP1501542B2 (de) |
AT (1) | ATE370745T1 (de) |
AU (2) | AU2002309259A1 (de) |
CA (1) | CA2484279A1 (de) |
DE (1) | DE60315827T3 (de) |
ES (1) | ES2293002T5 (de) |
WO (2) | WO2003094961A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0411815A (pt) * | 2003-06-23 | 2006-08-08 | Baxter Int | vacinas contra neisseria meningitidis do tipo y e suas combinações meningocócicas |
ATE548051T1 (de) | 2005-04-08 | 2012-03-15 | Wyeth Llc | Multivalente pneumokokken- polysaccharidproteinkonjugatzusammensetzung |
US7955605B2 (en) | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
US7709001B2 (en) * | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
US20070184072A1 (en) | 2005-04-08 | 2007-08-09 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
US8808707B1 (en) | 2006-05-08 | 2014-08-19 | Wyeth Llc | Pneumococcal dosing regimen |
ATE529448T1 (de) * | 2007-02-28 | 2011-11-15 | Lipoxen Technologies Ltd | Verringerung von endotoxin in polysialinsäuren |
GB0810894D0 (en) * | 2008-06-13 | 2008-07-23 | Novartis Vaccines & Diagnostic | Conjugated saccharide |
JP5841044B2 (ja) | 2009-03-23 | 2016-01-06 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. | 複合糖質ワクチン |
GB0915403D0 (en) * | 2009-09-04 | 2009-10-07 | London School Hygiene & Tropical Medicine | Protein glycosylation |
WO2011148382A1 (en) | 2010-05-28 | 2011-12-01 | Biological E Limited | An improved process for the purification of capsular polysaccharides of haemophilus influenza - b, neisseria meningitis such as serotypes a, c, y and w-135, and other similar related capsular polysaccharides produced from both gram negative and gram positive microorganisms using aluminium phosphate with alcohol. |
ITMI20130142A1 (it) * | 2013-01-31 | 2014-08-01 | Biosynth Srl | Vaccini glicoconiugati comprendenti unita' di base di un costrutto molecolare esprimente epitopi multipli incorporati |
EP3174553B1 (de) * | 2014-07-25 | 2018-04-18 | Biosynth S.R.L. | Glykokonjugat-vakzine mit basiseinheiten eines molekularen konstrukts mit mehreren integrierten epitopen zur formulierung eines breitbandimpfstoffes gegen infektionen durch enteropathogene bakterien |
AR104469A1 (es) | 2014-08-08 | 2017-07-26 | Glycovaxyn Ag | Células huésped modificadas para su uso en producción de bioconjugados |
US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
KR20190044663A (ko) | 2016-09-02 | 2019-04-30 | 사노피 파스퇴르 인크 | 네이세리아 메닌기티디스 백신 |
US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4663160A (en) * | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
US5153312A (en) * | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
US5371186A (en) * | 1991-02-11 | 1994-12-06 | Biosynth S.R.L. | Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock |
AU678549B2 (en) * | 1992-01-16 | 1997-06-05 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Detoxified LPS-cholera toxin conjugate vaccine for prevention of cholera |
IT1287158B1 (it) * | 1996-11-13 | 1998-08-04 | Biosynth Srl | Uso combinato di peptidi sintetici anti-endotossina e di anticorpi anti-endotossina per la profilassi ed il trattamento delle |
US6951652B2 (en) * | 1998-07-29 | 2005-10-04 | Biosynth S.R.L. | Vaccine for prevention of gram-negative bacterial infections and endotoxin related diseases |
-
2002
- 2002-05-09 WO PCT/IT2002/000307 patent/WO2003094961A1/en not_active Application Discontinuation
- 2002-05-09 AU AU2002309259A patent/AU2002309259A1/en not_active Abandoned
-
2003
- 2003-05-07 EP EP03749887A patent/EP1501542B2/de not_active Expired - Lifetime
- 2003-05-07 CA CA002484279A patent/CA2484279A1/en not_active Abandoned
- 2003-05-07 AT AT03749887T patent/ATE370745T1/de not_active IP Right Cessation
- 2003-05-07 WO PCT/EP2003/004948 patent/WO2003094959A1/en active IP Right Grant
- 2003-05-07 DE DE60315827T patent/DE60315827T3/de not_active Expired - Lifetime
- 2003-05-07 US US10/513,178 patent/US7588765B2/en not_active Expired - Lifetime
- 2003-05-07 ES ES03749887T patent/ES2293002T5/es not_active Expired - Lifetime
- 2003-05-07 AU AU2003242535A patent/AU2003242535A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20060165730A1 (en) | 2006-07-27 |
EP1501542A1 (de) | 2005-02-02 |
US7588765B2 (en) | 2009-09-15 |
ES2293002T5 (es) | 2012-03-20 |
DE60315827T2 (de) | 2008-05-15 |
EP1501542B2 (de) | 2011-11-02 |
ES2293002T3 (es) | 2008-03-16 |
DE60315827T3 (de) | 2012-04-26 |
DE60315827D1 (de) | 2007-10-04 |
WO2003094959A1 (en) | 2003-11-20 |
CA2484279A1 (en) | 2003-11-20 |
EP1501542B1 (de) | 2007-08-22 |
WO2003094961A1 (en) | 2003-11-20 |
AU2002309259A1 (en) | 2003-11-11 |
AU2003242535A1 (en) | 2003-11-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |