DE602006017331D1 - Kontrollierte produktion und zuführung biologisch aktiver stoffe durch darmbakterien - Google Patents
Kontrollierte produktion und zuführung biologisch aktiver stoffe durch darmbakterienInfo
- Publication number
- DE602006017331D1 DE602006017331D1 DE602006017331T DE602006017331T DE602006017331D1 DE 602006017331 D1 DE602006017331 D1 DE 602006017331D1 DE 602006017331 T DE602006017331 T DE 602006017331T DE 602006017331 T DE602006017331 T DE 602006017331T DE 602006017331 D1 DE602006017331 D1 DE 602006017331D1
- Authority
- DE
- Germany
- Prior art keywords
- biologically active
- bacteria
- darm
- supply
- active substances
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 241000894006 Bacteria Species 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 101710121765 Endo-1,4-beta-xylanase Proteins 0.000 abstract 1
- 230000037213 diet Effects 0.000 abstract 1
- 235000005911 diet Nutrition 0.000 abstract 1
- 229920001221 xylan Polymers 0.000 abstract 1
- 150000004823 xylans Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Botany (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0501540.9A GB0501540D0 (en) | 2005-01-25 | 2005-01-25 | Controlled production and delivery of biologically active agents by gut bacteria |
| PCT/GB2006/000222 WO2006079790A2 (en) | 2005-01-25 | 2006-01-24 | Controlled production and delivery of biologically active agents by gut bacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006017331D1 true DE602006017331D1 (de) | 2010-11-18 |
Family
ID=34259652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006017331T Active DE602006017331D1 (de) | 2005-01-25 | 2006-01-24 | Kontrollierte produktion und zuführung biologisch aktiver stoffe durch darmbakterien |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7988961B2 (enExample) |
| EP (1) | EP1841875B1 (enExample) |
| JP (1) | JP4989490B2 (enExample) |
| KR (1) | KR101291960B1 (enExample) |
| AT (1) | ATE483811T1 (enExample) |
| CA (1) | CA2640343C (enExample) |
| DE (1) | DE602006017331D1 (enExample) |
| ES (1) | ES2353721T3 (enExample) |
| GB (1) | GB0501540D0 (enExample) |
| WO (1) | WO2006079790A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9371510B2 (en) * | 2007-10-26 | 2016-06-21 | Brenda E. Moore | Probiotic compositions and methods for inducing and supporting weight loss |
| EP2258844A1 (en) | 2009-05-28 | 2010-12-08 | Helmholtz Zentrum Für Infektionsforschung | Tumour-specific bacterial promoter elements |
| CN102462837B (zh) * | 2010-11-19 | 2016-08-03 | 生物林格斯Ip有限公司 | 抗炎组合物 |
| WO2015095796A1 (en) | 2013-12-20 | 2015-06-25 | President And Fellows Of Harvard College | An engineered genetic enteric sensor bacteria and uses thereof |
| US9688967B2 (en) | 2014-12-05 | 2017-06-27 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| US20160206666A1 (en) | 2014-12-22 | 2016-07-21 | Synlogic, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tighten gut mucosal barrier |
| CA2971876A1 (en) * | 2014-12-22 | 2016-06-30 | Massachusetts Institute Of Technology | Probiotic organisms for diagnosis, monitoring, and treatment of inflammatory bowel disease |
| RU2017130462A (ru) * | 2015-03-02 | 2019-04-02 | Синлоджик, Инк. | Бактерия, созданная для лечения заболеваний, облегчаемых при уменьшении воспаления кишечника и/или укреплении мукозного барьера кишечника |
| ES2881384T3 (es) | 2015-05-13 | 2021-11-29 | Synlogic Operating Co Inc | Bacterias manipuladas para reducir la hiperfenilalaninemia |
| US11685925B2 (en) | 2015-10-30 | 2023-06-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| US11618894B2 (en) | 2015-11-16 | 2023-04-04 | Synlogic Operating Company, Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| AU2017252409B2 (en) * | 2016-04-20 | 2023-08-24 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for nucleic acid expression and protein secretion in bacteroides |
| EP3554518A4 (en) | 2016-12-15 | 2020-07-29 | The Board of Trustees of the Leland Stanford Junior University | COMPOSITIONS AND METHODS FOR MODULATING THE GROWTH OF A GENETICALLY MODIFIED INTESTINAL BACTERIAL CELL |
| KR20190122710A (ko) * | 2017-02-14 | 2019-10-30 | 캘리포니아 인스티튜트 오브 테크놀로지 | 행동 및 질환에서의 4-에틸페놀 및 4-에틸페놀 술페이트의 미생물적 합성의 조정 |
| US20200268813A1 (en) * | 2017-02-15 | 2020-08-27 | President And Fellows Of Harvard College | Modulation of host immune cell populations using gut microbiota |
| US11384358B2 (en) | 2017-03-29 | 2022-07-12 | President And Fellows Of Harvard College | Method of regulating gene expression in a cell |
| CN113454229A (zh) | 2018-12-10 | 2021-09-28 | 诺沃梅生物技术股份有限公司 | 用于治疗高草酸尿症的方法和组合物 |
| CN115298308A (zh) | 2020-03-20 | 2022-11-04 | 同生运营公司 | 经工程化以减轻高苯丙氨酸血症的微生物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0569604A1 (en) * | 1992-04-07 | 1993-11-18 | Societe Des Produits Nestle S.A. | Integrative gene-expression in Streptococcus salivarius ssp.thermophilus |
| DE60033823T2 (de) * | 1999-09-10 | 2007-12-06 | The Secretary Of State For Defence, Salisbury | Rekombinante mikroorganismen |
| JP2001275680A (ja) * | 2000-03-31 | 2001-10-09 | Yakult Honsha Co Ltd | β−1,3−キシラナーゼ遺伝子、該遺伝子を導入した微生物、及びβ−1,3−キシラナーゼの製造法 |
| JP2003144200A (ja) * | 2001-11-07 | 2003-05-20 | Yakult Honsha Co Ltd | バクテロイデスグループ細菌用プローブおよびこれを用いた検出方法 |
-
2005
- 2005-01-25 GB GBGB0501540.9A patent/GB0501540D0/en not_active Ceased
-
2006
- 2006-01-24 US US11/814,739 patent/US7988961B2/en not_active Expired - Fee Related
- 2006-01-24 AT AT06701043T patent/ATE483811T1/de not_active IP Right Cessation
- 2006-01-24 EP EP06701043A patent/EP1841875B1/en not_active Not-in-force
- 2006-01-24 JP JP2007551749A patent/JP4989490B2/ja not_active Expired - Fee Related
- 2006-01-24 KR KR1020077019503A patent/KR101291960B1/ko not_active Expired - Fee Related
- 2006-01-24 DE DE602006017331T patent/DE602006017331D1/de active Active
- 2006-01-24 WO PCT/GB2006/000222 patent/WO2006079790A2/en not_active Ceased
- 2006-01-24 CA CA2640343A patent/CA2640343C/en not_active Expired - Fee Related
- 2006-01-24 ES ES06701043T patent/ES2353721T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1841875A2 (en) | 2007-10-10 |
| KR101291960B1 (ko) | 2013-08-09 |
| KR20070108882A (ko) | 2007-11-13 |
| JP4989490B2 (ja) | 2012-08-01 |
| GB0501540D0 (en) | 2005-03-02 |
| US20080131402A1 (en) | 2008-06-05 |
| EP1841875B1 (en) | 2010-10-06 |
| CA2640343C (en) | 2014-01-14 |
| US7988961B2 (en) | 2011-08-02 |
| WO2006079790A2 (en) | 2006-08-03 |
| CA2640343A1 (en) | 2006-08-03 |
| WO2006079790A3 (en) | 2006-12-21 |
| JP2008527988A (ja) | 2008-07-31 |
| ES2353721T3 (es) | 2011-03-04 |
| ATE483811T1 (de) | 2010-10-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602006017331D1 (de) | Kontrollierte produktion und zuführung biologisch aktiver stoffe durch darmbakterien | |
| ES2486675T3 (es) | Análogo de péptido de oxintomodulina | |
| BR112012017345A2 (pt) | "composições e métodos de pgl para a produção aumentada de isopreno e outros produtos com 6-fosfogliconolactonase (pgl)" | |
| ES2534744T3 (es) | Plasmina modificada de forma recombinante | |
| PE20130593A1 (es) | DOMINIOS DE FIBRONECTINA TIPO III A LA DECIMA (10Fn3) MODIFICADOS DE UNION A SEROALBUMINA | |
| EA201590525A1 (ru) | Слитые белки для лечения метаболического синдрома | |
| MY180672A (en) | Ace2 polypeptide | |
| BR112013010487A2 (pt) | novos substratos de coelenterazina e métodos de uso | |
| NZ596037A (en) | Fgf21 mutants and uses thereof | |
| CO6430475A2 (es) | Polipéptidos que tienen actividad de celulasa | |
| MY159433A (en) | Fibrous materials and compositions | |
| MX2009013137A (es) | Metodos para seleccionar polipeptidos resistentes a la proteasa. | |
| EA201001883A1 (ru) | Мутанты fgf21 и их применение | |
| PE20120532A1 (es) | ANTICUERPOS ANTI-ActRIIB | |
| DE602007006492D1 (de) | Derivatisierung des granulozytenkoloniestimulierenden faktors | |
| NZ596658A (en) | Dig-10 insecticidal cry toxins | |
| DK1877435T4 (da) | Glucagon-lignende-peptid-2 (glp-2)-analoger | |
| EP2409988A3 (en) | Peptide fragments for inducing synthesis of extracellular matrix proteins | |
| GB0514779D0 (en) | Biological products | |
| EA201290542A1 (ru) | Модифицированные свиные соматотропиновые полипептиды и их применение | |
| EA201290541A1 (ru) | Модифицированные бычьи соматотропиновые полипептиды и их применение | |
| MY148447A (en) | Method for amidating polypeptides with basic aminoacid d-terminals by means of specific endoproteases | |
| AR053259A1 (es) | Trigo con nuevo almidon y metodo para producirlo | |
| ATE505205T1 (de) | Polymerkonjugate von box-a von hmgb1 und box-a- varianten von hmgb1 | |
| SG10201803541TA (en) | Biologically active c-terminal arginine-containing peptides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: PLANT BIOSCIENCE LTD., NORWICH, NORFOLK, GB |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: PATENTANWAELTE FREISCHEM, 50677 KOELN |