DE602006004473D1 - Nnrt-inhibitoren - Google Patents

Nnrt-inhibitoren

Info

Publication number
DE602006004473D1
DE602006004473D1 DE602006004473T DE602006004473T DE602006004473D1 DE 602006004473 D1 DE602006004473 D1 DE 602006004473D1 DE 602006004473 T DE602006004473 T DE 602006004473T DE 602006004473 T DE602006004473 T DE 602006004473T DE 602006004473 D1 DE602006004473 D1 DE 602006004473D1
Authority
DE
Germany
Prior art keywords
nnrt
inhibitors
nnrt inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006004473T
Other languages
English (en)
Inventor
Yoshihito David Saito
Mark Smith
Zachary Kevin Sweeney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE602006004473D1 publication Critical patent/DE602006004473D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C07D273/02Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having two nitrogen atoms and only one oxygen atom
    • C07D273/04Six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE602006004473T 2005-09-30 2006-09-20 Nnrt-inhibitoren Active DE602006004473D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72233505P 2005-09-30 2005-09-30
PCT/EP2006/066541 WO2007039463A1 (en) 2005-09-30 2006-09-20 Nnrt inhibitors

Publications (1)

Publication Number Publication Date
DE602006004473D1 true DE602006004473D1 (de) 2009-02-05

Family

ID=37685915

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006004473T Active DE602006004473D1 (de) 2005-09-30 2006-09-20 Nnrt-inhibitoren

Country Status (15)

Country Link
US (1) US7625897B2 (de)
EP (1) EP1937651B1 (de)
JP (1) JP2009510013A (de)
KR (1) KR20080064957A (de)
CN (1) CN101273020A (de)
AR (1) AR055666A1 (de)
AT (1) ATE418545T1 (de)
AU (1) AU2006298853A1 (de)
BR (1) BRPI0617205A2 (de)
CA (1) CA2623728A1 (de)
DE (1) DE602006004473D1 (de)
ES (1) ES2317584T3 (de)
IL (1) IL190081A0 (de)
TW (1) TW200800923A (de)
WO (1) WO2007039463A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7834178B2 (en) * 2006-03-01 2010-11-16 Bristol-Myers Squibb Company Triazine 11-beta hydroxysteroid dehydrogenase type 1 inhibitors
GB0610680D0 (en) * 2006-05-31 2006-07-12 Istituto Di Ricerche D Biolog Therapeutic compounds
CL2007002105A1 (es) * 2006-07-21 2008-02-22 Hoffmann La Roche Compuestos derivados de 2-[3-(3-cianofenoxi)(fenoxi o fenilsulfanil)]-n-fenil acetamida, inhibidores de la transcriptasa inversa del vih; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar u
KR101401811B1 (ko) * 2006-08-16 2014-05-29 에프. 호프만-라 로슈 아게 비-뉴클레오사이드 역전사효소 저해제
KR101542629B1 (ko) * 2007-05-30 2015-08-06 에프. 호프만-라 로슈 아게 비-뉴클레오사이드 역전사효소 억제제
KR20100039348A (ko) * 2007-06-22 2010-04-15 에프. 호프만-라 로슈 아게 비-뉴클레오사이드 역 전사효소 억제제로서 우레아 및 카바메이트 유도체
BRPI0821349A2 (pt) * 2007-12-21 2019-09-24 Hoffmann La Roche compostos antivirais heterocíclicos
TWI490214B (zh) 2008-05-30 2015-07-01 艾德克 上野股份有限公司 苯或噻吩衍生物及該等作為vap-1抑制劑之用途
KR20110094352A (ko) * 2008-12-22 2011-08-23 에프. 호프만-라 로슈 아게 헤테로사이클릭 항바이러스 화합물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6405596A (en) 1995-06-30 1997-02-05 Smithkline Beecham Corporation Use of stat 5 sh2 domain specific compounds to enhance erythropoiesis
CN1136197C (zh) 1996-05-30 2004-01-28 霍夫曼-拉罗奇有限公司 新的哒嗪酮衍生物
TW200505441A (en) * 2003-03-24 2005-02-16 Hoffmann La Roche Non-nucleoside reverse transcriptase inhibitorsⅠ
AU2004224191A1 (en) * 2003-03-24 2004-10-07 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
EP1730120A1 (de) 2004-03-23 2006-12-13 F.Hoffmann-La Roche Ag Inhibitoren der nicht-nukleosid-inhibitoren der reversen transkriptase

Also Published As

Publication number Publication date
AR055666A1 (es) 2007-08-29
CA2623728A1 (en) 2007-04-12
CN101273020A (zh) 2008-09-24
WO2007039463A1 (en) 2007-04-12
KR20080064957A (ko) 2008-07-10
AU2006298853A1 (en) 2007-04-12
EP1937651B1 (de) 2008-12-24
IL190081A0 (en) 2008-08-07
EP1937651A1 (de) 2008-07-02
BRPI0617205A2 (pt) 2011-07-19
TW200800923A (en) 2008-01-01
US20070078128A1 (en) 2007-04-05
JP2009510013A (ja) 2009-03-12
ATE418545T1 (de) 2009-01-15
ES2317584T3 (es) 2009-04-16
US7625897B2 (en) 2009-12-01

Similar Documents

Publication Publication Date Title
LTPA2017010I1 (lt) Proteazomos inhibitoriai
LTC1907382I2 (lt) Nitrokatechnolio dariniai, kaip COMT inhibitoriai
DK2041138T3 (da) Pyrroltriazinkinase-inhibitorer
DK2024375T3 (da) Cyclopropyl-kondenserede indolobenzazepin-HCV-NS5B-hæmmere
NO20076678L (no) Glutamataggrekanaseinhibitorer
CR10831A (es) INHIBIDORES ESPIRO CETONA DE ACETIL-CoA CARBOXILASA
DK1940839T3 (da) Pyridopyrimidione Inhibitors of P13Ka
BRPI0807547A2 (pt) Inibidores de aspartil protease hetercíclicos
DK1979356T3 (da) Carbonylaminopyrrolopyrazoler, kraftige kinaseinhibitorer
DK1962830T3 (da) Azaindolhæmmere af aurorakinaser.
DK2086939T3 (da) Pyridiacarboxamid som II-beta-HSDI-inhibitorer
BRPI0719204A2 (pt) Inibidores de hdac
DK1934236T3 (da) Heterobifunktionelle pan-selektininhibitorer
DK2253614T3 (da) IAP-inhibitorer
DK1778718T3 (da) Iap-inhibitorer
DK1943243T3 (da) Kinase-inhibitorer
DK2074108T3 (da) Renin-inhibitorer
DK1713805T3 (da) Kinaseinhibitorer
DK2066662T3 (da) Serinhydrolaseinhibitorer
ATE418545T1 (de) Nnrt-inhibitoren
DK1943388T3 (da) Køretøjs-indtrængningshæmmere
DK1991718T3 (da) Korrosionsinhibitorer
ATE522533T1 (de) Pyrazolopyrimidinonkinaseinhibitor
DE602007009087D1 (de) Zerebraler vasospasmus-inhibitor
FI20050681A0 (fi) Paikoitusmenetelmä

Legal Events

Date Code Title Description
8364 No opposition during term of opposition