DE602005024623D1 - Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe - Google Patents

Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe

Info

Publication number
DE602005024623D1
DE602005024623D1 DE602005024623T DE602005024623T DE602005024623D1 DE 602005024623 D1 DE602005024623 D1 DE 602005024623D1 DE 602005024623 T DE602005024623 T DE 602005024623T DE 602005024623 T DE602005024623 T DE 602005024623T DE 602005024623 D1 DE602005024623 D1 DE 602005024623D1
Authority
DE
Germany
Prior art keywords
alkyl
acid derivatives
betuline
condensate
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005024623T
Other languages
English (en)
Inventor
Rama Mukherjee
Sanjay K Srivastava
Mohammad J A Siddiqui
Manu Jaggi
Anu T Singh
Anand Vardhan
Manoj Kumar Singh
Praveen Rajendran
Hemant Jajoo
Anand C Burman
Vivek Kumar
Nidhi Rani
Shiv Agarwal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Kabi Oncology Ltd
Original Assignee
Dabur Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dabur Pharma Ltd filed Critical Dabur Pharma Ltd
Publication of DE602005024623D1 publication Critical patent/DE602005024623D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0047—Nitrogen only at position 2(3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE602005024623T 2005-02-09 2005-12-29 Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe Active DE602005024623D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN265DE2005 2005-02-09
PCT/IN2005/000445 WO2006085334A2 (en) 2005-02-09 2005-12-29 Novel betulinic acid derivatives a-ring-condensed to a heterocyclic group

Publications (1)

Publication Number Publication Date
DE602005024623D1 true DE602005024623D1 (de) 2010-12-16

Family

ID=36793451

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005024623T Active DE602005024623D1 (de) 2005-02-09 2005-12-29 Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe

Country Status (12)

Country Link
US (1) US8022055B2 (de)
EP (1) EP1858910B1 (de)
KR (1) KR101068259B1 (de)
AT (1) ATE486886T1 (de)
AU (1) AU2005327442B2 (de)
BR (1) BRPI0519948A2 (de)
CA (1) CA2597300C (de)
DE (1) DE602005024623D1 (de)
EA (1) EA013158B1 (de)
NZ (1) NZ560734A (de)
WO (1) WO2006085334A2 (de)
ZA (1) ZA200706393B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9062197B2 (en) * 2009-03-27 2015-06-23 Eastman Chemical Company Polyester blends
PL227790B1 (pl) 2015-08-13 2018-01-31 Slaski Univ Medyczny W Katowicach Fosfoniany acetylenowych pochodnych betuliny o działaniu przeciwnowotworowym, sposób ich wytwarzania i zastosowanie.
MX2020002884A (es) 2017-09-14 2020-10-05 Phoenix Biotechnology Inc Método y composición neuroprotectora mejorada para tratar afecciones neurológicas.
EP3681508A4 (de) 2017-09-14 2021-05-19 Phoenix Biotechnology, Inc. Verfahren und zusammensetzung zur behandlung von virusinfektionen
RU2020130238A (ru) 2020-03-31 2022-03-14 Феникс Байотекнолоджи, Инк. Способ и композиции для лечения коронавирусной инфекции
EP4009981B1 (de) 2020-03-31 2023-08-16 Phoenix Biotechnology, Inc. Verfahren und zusammensetzungen zur behandlung von coronavirusinfektionen

Also Published As

Publication number Publication date
EA013158B1 (ru) 2010-02-26
AU2005327442A1 (en) 2006-08-17
ZA200706393B (en) 2009-11-25
EA200701689A1 (ru) 2008-02-28
WO2006085334A3 (en) 2007-06-14
US8022055B2 (en) 2011-09-20
KR20070107717A (ko) 2007-11-07
NZ560734A (en) 2010-09-30
EP1858910A2 (de) 2007-11-28
CA2597300A1 (en) 2006-08-17
WO2006085334A2 (en) 2006-08-17
EP1858910B1 (de) 2010-11-03
BRPI0519948A2 (pt) 2009-12-01
AU2005327442B2 (en) 2011-09-01
KR101068259B1 (ko) 2011-09-28
CA2597300C (en) 2012-11-27
ATE486886T1 (de) 2010-11-15
US20080293682A1 (en) 2008-11-27

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: FRESENIUS KABI ONCOLOGY LTD., NEW DEHLI, IN