ATE486886T1 - Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe - Google Patents

Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe

Info

Publication number
ATE486886T1
ATE486886T1 AT05850957T AT05850957T ATE486886T1 AT E486886 T1 ATE486886 T1 AT E486886T1 AT 05850957 T AT05850957 T AT 05850957T AT 05850957 T AT05850957 T AT 05850957T AT E486886 T1 ATE486886 T1 AT E486886T1
Authority
AT
Austria
Prior art keywords
alkyl
acid derivatives
betulinic acid
ring
heterocyclic group
Prior art date
Application number
AT05850957T
Other languages
English (en)
Inventor
Rama Mukherjee
Sanjay K Srivastava
Mohammad J A Siddiqui
Manu Jaggi
Anu T Singh
Anand Vardhan
Manoj Kumar Singh
Praveen Rajendran
Hemant Kumar Jajoo
Anand C Burman
Vivek Kumar
Nidhi Rani
Shiv Kumar Agarwal
Original Assignee
Dabur Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dabur Pharma Ltd filed Critical Dabur Pharma Ltd
Application granted granted Critical
Publication of ATE486886T1 publication Critical patent/ATE486886T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036Nitrogen-containing hetero ring
    • C07J71/0042Nitrogen only
    • C07J71/0047Nitrogen only at position 2(3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
AT05850957T 2005-02-09 2005-12-29 Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe ATE486886T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN265DE2005 2005-02-09
PCT/IN2005/000445 WO2006085334A2 (en) 2005-02-09 2005-12-29 Novel betulinic acid derivatives a-ring-condensed to a heterocyclic group

Publications (1)

Publication Number Publication Date
ATE486886T1 true ATE486886T1 (de) 2010-11-15

Family

ID=36793451

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05850957T ATE486886T1 (de) 2005-02-09 2005-12-29 Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe

Country Status (12)

Country Link
US (1) US8022055B2 (de)
EP (1) EP1858910B1 (de)
KR (1) KR101068259B1 (de)
AT (1) ATE486886T1 (de)
AU (1) AU2005327442B2 (de)
BR (1) BRPI0519948A2 (de)
CA (1) CA2597300C (de)
DE (1) DE602005024623D1 (de)
EA (1) EA013158B1 (de)
NZ (1) NZ560734A (de)
WO (1) WO2006085334A2 (de)
ZA (1) ZA200706393B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9062197B2 (en) * 2009-03-27 2015-06-23 Eastman Chemical Company Polyester blends
PL227790B1 (pl) 2015-08-13 2018-01-31 Slaski Univ Medyczny W Katowicach Fosfoniany acetylenowych pochodnych betuliny o działaniu przeciwnowotworowym, sposób ich wytwarzania i zastosowanie.
CA3075023A1 (en) 2017-09-14 2019-03-21 Phoenix Biotechnology, Inc. Method and improved neuroprotective composition for treating neurological conditions
CA3075729A1 (en) 2017-09-14 2019-03-21 Phoenix Biotechnology, Inc. Use of oleandrin to treatn viral infection
EP4009981B1 (de) 2020-03-31 2023-08-16 Phoenix Biotechnology, Inc. Verfahren und zusammensetzungen zur behandlung von coronavirusinfektionen
MX2020009095A (es) 2020-03-31 2022-07-28 Phoenix Biotechnology Inc Metodo y composiciones para el tratamiento de infeccion por coronavirus.

Also Published As

Publication number Publication date
DE602005024623D1 (de) 2010-12-16
AU2005327442A1 (en) 2006-08-17
EP1858910B1 (de) 2010-11-03
ZA200706393B (en) 2009-11-25
EP1858910A2 (de) 2007-11-28
US20080293682A1 (en) 2008-11-27
EA013158B1 (ru) 2010-02-26
WO2006085334A2 (en) 2006-08-17
CA2597300C (en) 2012-11-27
BRPI0519948A2 (pt) 2009-12-01
KR20070107717A (ko) 2007-11-07
EA200701689A1 (ru) 2008-02-28
CA2597300A1 (en) 2006-08-17
WO2006085334A3 (en) 2007-06-14
AU2005327442B2 (en) 2011-09-01
US8022055B2 (en) 2011-09-20
KR101068259B1 (ko) 2011-09-28
NZ560734A (en) 2010-09-30

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