DE602005019064D1 - Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren - Google Patents

Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren

Info

Publication number
DE602005019064D1
DE602005019064D1 DE602005019064T DE602005019064T DE602005019064D1 DE 602005019064 D1 DE602005019064 D1 DE 602005019064D1 DE 602005019064 T DE602005019064 T DE 602005019064T DE 602005019064 T DE602005019064 T DE 602005019064T DE 602005019064 D1 DE602005019064 D1 DE 602005019064D1
Authority
DE
Germany
Prior art keywords
blood plates
preparing
freezerted
fluidized
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005019064T
Other languages
German (de)
English (en)
Inventor
David Ho
Cindy S Orser
Alan S Rudolph
Keith A Moskowitz
Joshua Dee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cellphire Inc
Original Assignee
Cellphire Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/152,774 external-priority patent/US20060035383A1/en
Priority claimed from US11/197,310 external-priority patent/US20060051731A1/en
Application filed by Cellphire Inc filed Critical Cellphire Inc
Publication of DE602005019064D1 publication Critical patent/DE602005019064D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dentistry (AREA)
  • Molecular Biology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602005019064T 2004-08-12 2005-08-12 Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren Expired - Lifetime DE602005019064D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US60083804P 2004-08-12 2004-08-12
US61993004P 2004-10-20 2004-10-20
US11/152,774 US20060035383A1 (en) 2004-08-12 2005-06-15 Dry platelet preparations for use in diagnostics
US11/197,310 US20060051731A1 (en) 2004-08-12 2005-08-05 Processes for preparing lyophilized platelets
PCT/US2005/028559 WO2006020773A2 (en) 2004-08-12 2005-08-12 Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use

Publications (1)

Publication Number Publication Date
DE602005019064D1 true DE602005019064D1 (de) 2010-03-11

Family

ID=35908143

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005019064T Expired - Lifetime DE602005019064D1 (de) 2004-08-12 2005-08-12 Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren

Country Status (10)

Country Link
US (1) US8486617B2 (https=)
EP (1) EP1784639B1 (https=)
JP (1) JP5138372B2 (https=)
CN (1) CN101072506B (https=)
AT (1) ATE455463T1 (https=)
AU (1) AU2005272821B2 (https=)
CA (1) CA2577068C (https=)
DE (1) DE602005019064D1 (https=)
NZ (1) NZ553389A (https=)
WO (1) WO2006020773A2 (https=)

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JP5478884B2 (ja) 2005-09-26 2014-04-23 ライフセル コーポレーション 乾燥血小板組成物
US8058064B2 (en) * 2006-10-04 2011-11-15 The University Of Tokyo Sac-like structure enclosing hematopoietic progenitor cells produced from ES cells and method for preparing blood cells
US8372343B2 (en) * 2007-12-07 2013-02-12 Sheldon Goldstein Multiple coagulation test cartridge and method of using same
WO2010022202A1 (en) * 2008-08-20 2010-02-25 Bio/Data Corporation Kinetic biologic activity assays and kinetic von willebrand assay
US20100049542A1 (en) * 2008-08-22 2010-02-25 Fenwal, Inc. Systems, articles of manufacture, and methods for managing blood processing procedures
WO2011124280A1 (en) * 2010-04-08 2011-10-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Zeodration method for the preservation of blood platelets
US10575515B2 (en) 2010-05-04 2020-03-03 The General Hospital Corporation Methods and compositions for preserving tissues and organs
EP2598660B1 (en) 2010-07-26 2017-03-15 Biomatrica, INC. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
WO2012018639A2 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
CN101957364A (zh) * 2010-09-19 2011-01-26 李勇 冻干型血小板抗原谱细胞的制备方法
GB201101002D0 (en) * 2011-01-20 2011-03-09 Biopharma Technology Ltd Freeze drying method
WO2012098358A1 (en) * 2011-01-20 2012-07-26 Biopharma Technology Ltd Freeze drying method
EP2508892A1 (de) * 2011-04-04 2012-10-10 Siemens Healthcare Diagnostics Products GmbH Kontrollen und Kit für Thrombozytenaktivitätsteste
CN102327288B (zh) * 2011-10-17 2012-11-14 济南环肽医药科技有限公司 一种注射用血小板冻干粉制剂及其制备方法
US9725703B2 (en) 2012-12-20 2017-08-08 Biomatrica, Inc. Formulations and methods for stabilizing PCR reagents
AU2013204728B2 (en) 2013-03-15 2016-09-15 Baxalta GmbH Methods for treating bleeding disorders using a platelet subpopulation
JP6448615B2 (ja) * 2013-03-15 2019-01-09 クック・バイオテック・インコーポレイテッドＣｏｏｋ Ｂｉｏｔｅｃｈ Ｉｎｃｏｒｐｏｒａｔｅｄ Ｅｃｍ移植組成物および方法
TW201446253A (zh) * 2013-06-07 2014-12-16 Chang Gung Medical Foundation Lin Kou Chang Gung Memorial Hospital 非凝集預活變形血小板之應用及其藥劑
ES2786373T3 (es) * 2014-06-10 2020-10-09 Biomatrica Inc Estabilización de trombocitos a temperaturas ambiente
EP3698628A1 (en) * 2014-08-07 2020-08-26 The General Hospital Corporation Stabilization of whole blood samples
KR20170102319A (ko) * 2014-12-31 2017-09-08 안트로제네시스 코포레이션 혈소판을 분리하는 방법
CN107405391B (zh) * 2015-03-04 2021-03-19 罗切斯特大学 治疗外伤患者中的出血的血小板微粒的全身和局部应用
JP2018516965A (ja) * 2015-06-10 2018-06-28 セルフィアー インコーポレイテッド 低血圧（ｈｙｐｏｔｅｎｓｉｏｎ）および／または血液量減少（ｈｙｐｏｖｏｌｅｍｉａ）に至る体液（ｆｌｕｉｄｓ）の喪失の治療のための組成物および方法
WO2017040238A1 (en) * 2015-08-28 2017-03-09 Cellphire, Inc. Products and methods using a platelet-derived hemostatic agent for controlling bleeding and improving healing
KR20250047404A (ko) 2015-12-08 2025-04-03 바이오매트리카 인코포레이티드 적혈구 침강 속도의 감소
CN108603853B (zh) * 2016-02-10 2022-08-09 索尼公司 电特性测量用样本、电特性测量装置和电特性测量方法
EP3551198B1 (en) * 2016-12-08 2022-02-02 Cellphire Inc. Compositions and methods for treatment of loss of fluids leading to hypotension and/or hypovolemia
CN110381962B (zh) * 2016-12-21 2023-10-13 孙崇谨 用于血浆蛋白的活性保存的新颖方法
EP3681518A4 (en) * 2017-09-13 2021-06-23 Cellphire Inc. DOG'S BLOOD PLATE PREPARATIONS
CN107998375B (zh) * 2017-12-14 2021-11-05 广东医科大学 一种多肽在预防或治疗血栓性疾病或脑缺血再灌注损伤相关疾病中的应用
CA3121200A1 (en) * 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
WO2020112963A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
EP3937631A4 (en) * 2019-03-13 2023-01-04 Cellphire Inc. DOG PLALETLET PREPARATIONS
US10429377B1 (en) 2019-03-15 2019-10-01 Coagulation Sciences Llc Coagulation test device, system, and method of use
IL322149A (en) * 2019-05-03 2025-09-01 Cellphire Inc Materials and methods for manufacturing blood products
US20210100846A1 (en) * 2019-07-17 2021-04-08 Cellphire, Inc. Use of platelets in treating infections
WO2023220739A1 (en) 2022-05-12 2023-11-16 Cellphire, Inc. Platelet derivative compositions for use in subjects afflicted with hermansky pudlak syndrome or bernard soulier syndrome
CN114450066A (zh) * 2019-08-16 2022-05-06 塞尔菲乐有限公司 作为抗血小板剂逆转剂的血栓小体
EP4013432A4 (en) * 2019-08-16 2023-10-18 Cellphire Inc. THROMBOSOMES AS A MEANS OF REMOVING THE ANTICOLOTTING EFFECT
WO2023081804A1 (en) 2021-11-04 2023-05-11 Cellphire, Inc. Platelet derivative compositions, and methods of making and using such compositions
WO2022178177A1 (en) 2021-02-17 2022-08-25 Cellphire, Inc. Freeze-dried platelet derivative compositions for treating antiplatelet-induced coagulopathy
CN110585240B (zh) * 2019-10-10 2021-10-29 石开生物科技(广州)有限公司 一种含再生因子的冻干制剂及其制备方法和应用
WO2021108538A1 (en) * 2019-11-27 2021-06-03 Cellphire, Inc. PLATELETS LOADED WITH mRNA
CA3170196A1 (en) * 2020-02-04 2021-08-12 Cellphire, Inc. Anti-fibrinolytic loaded platelets
WO2021232015A1 (en) * 2020-05-15 2021-11-18 Cellphire, Inc. Platelet derived extracellular vesicles
CN113156144A (zh) * 2021-01-29 2021-07-23 郑州普湾医疗技术有限公司 一种血小板聚集功能花生四烯酸杯检测试剂及其制备方法
WO2022178191A1 (en) 2021-02-17 2022-08-25 Cellphire, Inc. Freeze-dried platelet derivative compositions for treating anticoagulant-induced coagulopathy
TW202245814A (zh) * 2021-02-17 2022-12-01 美商賽菲爾公司 用於治療抗血小板誘導的凝血病之凍乾血小板衍生物組成物
EP4086634A1 (en) * 2021-05-06 2022-11-09 Eberhard Karls Universität Tübingen Medizinische Fakultät Method for diagnosing a predisposition of a living being to develop thrombocytopenia
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Also Published As

Publication number Publication date
EP1784639B1 (en) 2010-01-20
AU2005272821A1 (en) 2006-02-23
CA2577068C (en) 2016-05-17
ATE455463T1 (de) 2010-02-15
AU2005272821B2 (en) 2010-09-09
EP1784639A4 (en) 2008-05-07
US8486617B2 (en) 2013-07-16
EP1784639A2 (en) 2007-05-16
CA2577068A1 (en) 2006-02-23
CN101072506B (zh) 2010-05-12
JP5138372B2 (ja) 2013-02-06
WO2006020773A3 (en) 2007-07-12
JP2008509924A (ja) 2008-04-03
US20070243178A1 (en) 2007-10-18
CN101072506A (zh) 2007-11-14
WO2006020773A2 (en) 2006-02-23
NZ553389A (en) 2009-10-30

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