DE602005016014D1 - Inhibitoren der cdc25 phosphatase - Google Patents
Inhibitoren der cdc25 phosphataseInfo
- Publication number
- DE602005016014D1 DE602005016014D1 DE602005016014T DE602005016014T DE602005016014D1 DE 602005016014 D1 DE602005016014 D1 DE 602005016014D1 DE 602005016014 T DE602005016014 T DE 602005016014T DE 602005016014 T DE602005016014 T DE 602005016014T DE 602005016014 D1 DE602005016014 D1 DE 602005016014D1
- Authority
- DE
- Germany
- Prior art keywords
- inhibitors
- cdc25 phosphatase
- cdc25
- phosphatase
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0413456A FR2879598B1 (fr) | 2004-12-17 | 2004-12-17 | Inhibiteurs de phosphatases cdc25 |
PCT/FR2005/003161 WO2006067311A2 (fr) | 2004-12-17 | 2005-12-16 | Inhibiteurs de phosphatases cdc25 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005016014D1 true DE602005016014D1 (de) | 2009-09-24 |
Family
ID=34954106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005016014T Active DE602005016014D1 (de) | 2004-12-17 | 2005-12-16 | Inhibitoren der cdc25 phosphatase |
Country Status (15)
Country | Link |
---|---|
US (1) | US8017637B2 (de) |
EP (1) | EP1831209B1 (de) |
JP (1) | JP2008524175A (de) |
AT (1) | ATE439359T1 (de) |
CA (1) | CA2591215A1 (de) |
CY (1) | CY1109596T1 (de) |
DE (1) | DE602005016014D1 (de) |
DK (1) | DK1831209T3 (de) |
ES (1) | ES2331199T3 (de) |
FR (1) | FR2879598B1 (de) |
PL (1) | PL1831209T3 (de) |
PT (1) | PT1831209E (de) |
RU (1) | RU2395510C2 (de) |
SI (1) | SI1831209T1 (de) |
WO (1) | WO2006067311A2 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2834289B1 (fr) | 2001-12-27 | 2004-03-19 | Sod Conseils Rech Applic | Derives de benzothiazole-4,7-diones et benzooxazole-4,7- diones, leur preparation et leurs applications therapeutiques |
FR2877667B1 (fr) * | 2004-11-05 | 2007-03-23 | Sod Conseils Rech Applic | Derives de 4,7-dioxobenzothiazole-2-carboxamides, leur preparation et leurs applications therapeutiques |
FR2879598B1 (fr) | 2004-12-17 | 2007-03-30 | Sod Conseils Rech Applic | Inhibiteurs de phosphatases cdc25 |
FR2915747B1 (fr) * | 2007-05-04 | 2011-02-25 | Scras | Derives de tri-amino-pyrimidine comme inhibiteurs de phosphatase cdc25 |
FR2930552B1 (fr) * | 2008-04-24 | 2012-10-12 | Centre Nat Rech Scient | N-acylthiourees et n-acylurees inhibiteurs de la voie de signalisation des proteines hedgehog |
FR2945532A1 (fr) * | 2009-05-15 | 2010-11-19 | Ipsen Pharma Sas | Derives de tri-amino-pyrimidine comme inhibiteurs de phosphatases cdc25 |
PT2968316T (pt) | 2013-03-13 | 2019-10-29 | Forma Therapeutics Inc | Derivados de 2-hidroxi-1-{4-[(4-fenilfenil)carbonil]piperazin-1-il}etano-1-ona e compostos relacionados como inibidores da sintase de ácidos gordos (fasn) para o tratamento do cancro |
US10179914B2 (en) | 2014-09-26 | 2019-01-15 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | CDC25A inhibitor for the treatment of drug resistant cancer or for the prevention of tumor relapse |
TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
CN113382633A (zh) | 2018-10-29 | 2021-09-10 | 福马治疗股份有限公司 | (4-(2-氟-4-(1-甲基-1H-苯并[d]咪唑-5-基)苯甲酰基)哌嗪-1-基)(1-羟基环丙基)甲酮的固体形式 |
WO2022018667A1 (en) | 2020-07-24 | 2022-01-27 | Pfizer Inc. | Combination therapies using cdk2 and cdc25a inhibitors |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1534275A (en) | 1976-01-30 | 1978-11-29 | Shell Int Research | Herbicidal compositions containing 1,4-quinones or derivatives thereof |
US5508289A (en) * | 1994-03-14 | 1996-04-16 | The United States America As Represented By The Department Of Health And Human Services | Bis-acridone chemotherapeutic derivatives |
US5523430A (en) | 1994-04-14 | 1996-06-04 | Bristol-Myers Squibb Company | Protein farnesyl transferase inhibitors |
US6673927B2 (en) | 1996-02-16 | 2004-01-06 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Farnesyl transferase inhibitors |
IT1293525B1 (it) * | 1997-08-01 | 1999-03-01 | Uni Degli Studi Camerino | Bis-acridincarbossiammidi aventi attivita' antitumorale |
JP2003513940A (ja) | 1999-11-09 | 2003-04-15 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・(エス.セー.エール.アー.エス) | ヘテロ三量体gタンパク質情報の伝達抑制剤と他の抗癌剤とからなる、癌の処置において治療の目的に使用する製品 |
ATE305785T1 (de) | 1999-12-21 | 2005-10-15 | Cd45 hemmer | |
AR037714A1 (es) | 2001-12-06 | 2004-12-01 | Maxia Pharmaceuticals Inc | Derivados de tiazolidinona y oxazolidinona 2-sustituidos para la inhibicion de fosfatasas y el tratamiento de cancer |
FR2834289B1 (fr) | 2001-12-27 | 2004-03-19 | Sod Conseils Rech Applic | Derives de benzothiazole-4,7-diones et benzooxazole-4,7- diones, leur preparation et leurs applications therapeutiques |
CN100425600C (zh) * | 2001-12-27 | 2008-10-15 | 科学研究和应用咨询公司 | 苯并噻唑-和苯并唑-4,7-二酮衍生物及其作为cdc25磷酸酯酶抑制剂的用途 |
FR2856686A1 (fr) | 2003-06-25 | 2004-12-31 | Sod Conseils Rech Applic | Benzothiazole-4,7-diones et benzooxazole-4,7-diones substituees en position 5 ou 6 et leurs procedes de preparation |
FR2856688B1 (fr) | 2003-06-25 | 2008-05-30 | Sod Conseils Rech Applic | PRODUIT COMPRENANT AU MOINS UN INHIBITEUR DE PHOSPHATASE CDc25 EN ASSOCIATION AVEC AU MOINS UN AUTRE AGENT ANTI-CANCEREUX |
FR2877667B1 (fr) | 2004-11-05 | 2007-03-23 | Sod Conseils Rech Applic | Derives de 4,7-dioxobenzothiazole-2-carboxamides, leur preparation et leurs applications therapeutiques |
FR2879598B1 (fr) | 2004-12-17 | 2007-03-30 | Sod Conseils Rech Applic | Inhibiteurs de phosphatases cdc25 |
-
2004
- 2004-12-17 FR FR0413456A patent/FR2879598B1/fr not_active Expired - Fee Related
-
2005
- 2005-12-16 JP JP2007546121A patent/JP2008524175A/ja active Pending
- 2005-12-16 PL PL05826562T patent/PL1831209T3/pl unknown
- 2005-12-16 US US11/722,075 patent/US8017637B2/en not_active Expired - Fee Related
- 2005-12-16 PT PT05826562T patent/PT1831209E/pt unknown
- 2005-12-16 DE DE602005016014T patent/DE602005016014D1/de active Active
- 2005-12-16 SI SI200530820T patent/SI1831209T1/sl unknown
- 2005-12-16 AT AT05826562T patent/ATE439359T1/de active
- 2005-12-16 ES ES05826562T patent/ES2331199T3/es active Active
- 2005-12-16 RU RU2007127250/04A patent/RU2395510C2/ru not_active IP Right Cessation
- 2005-12-16 CA CA002591215A patent/CA2591215A1/fr not_active Abandoned
- 2005-12-16 WO PCT/FR2005/003161 patent/WO2006067311A2/fr active Application Filing
- 2005-12-16 EP EP05826562A patent/EP1831209B1/de not_active Not-in-force
- 2005-12-16 DK DK05826562T patent/DK1831209T3/da active
-
2009
- 2009-11-11 CY CY20091101174T patent/CY1109596T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2006067311A3 (fr) | 2006-08-17 |
EP1831209B1 (de) | 2009-08-12 |
PT1831209E (pt) | 2009-11-04 |
PL1831209T3 (pl) | 2010-01-29 |
SI1831209T1 (sl) | 2010-01-29 |
DK1831209T3 (da) | 2009-11-30 |
CY1109596T1 (el) | 2014-08-13 |
ES2331199T3 (es) | 2009-12-23 |
ATE439359T1 (de) | 2009-08-15 |
CA2591215A1 (fr) | 2006-06-29 |
EP1831209A2 (de) | 2007-09-12 |
JP2008524175A (ja) | 2008-07-10 |
RU2007127250A (ru) | 2009-01-27 |
WO2006067311A2 (fr) | 2006-06-29 |
US8017637B2 (en) | 2011-09-13 |
FR2879598B1 (fr) | 2007-03-30 |
RU2395510C2 (ru) | 2010-07-27 |
US20090275624A1 (en) | 2009-11-05 |
FR2879598A1 (fr) | 2006-06-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |