DK1831209T3 - Inhibitorer af CDC25-phosphatase - Google Patents
Inhibitorer af CDC25-phosphataseInfo
- Publication number
- DK1831209T3 DK1831209T3 DK05826562T DK05826562T DK1831209T3 DK 1831209 T3 DK1831209 T3 DK 1831209T3 DK 05826562 T DK05826562 T DK 05826562T DK 05826562 T DK05826562 T DK 05826562T DK 1831209 T3 DK1831209 T3 DK 1831209T3
- Authority
- DK
- Denmark
- Prior art keywords
- inhibitors
- cdc25 phosphatase
- cdc25
- phosphatase
- dione
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0413456A FR2879598B1 (fr) | 2004-12-17 | 2004-12-17 | Inhibiteurs de phosphatases cdc25 |
PCT/FR2005/003161 WO2006067311A2 (fr) | 2004-12-17 | 2005-12-16 | Inhibiteurs de phosphatases cdc25 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1831209T3 true DK1831209T3 (da) | 2009-11-30 |
Family
ID=34954106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05826562T DK1831209T3 (da) | 2004-12-17 | 2005-12-16 | Inhibitorer af CDC25-phosphatase |
Country Status (15)
Country | Link |
---|---|
US (1) | US8017637B2 (da) |
EP (1) | EP1831209B1 (da) |
JP (1) | JP2008524175A (da) |
AT (1) | ATE439359T1 (da) |
CA (1) | CA2591215A1 (da) |
CY (1) | CY1109596T1 (da) |
DE (1) | DE602005016014D1 (da) |
DK (1) | DK1831209T3 (da) |
ES (1) | ES2331199T3 (da) |
FR (1) | FR2879598B1 (da) |
PL (1) | PL1831209T3 (da) |
PT (1) | PT1831209E (da) |
RU (1) | RU2395510C2 (da) |
SI (1) | SI1831209T1 (da) |
WO (1) | WO2006067311A2 (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2834289B1 (fr) | 2001-12-27 | 2004-03-19 | Sod Conseils Rech Applic | Derives de benzothiazole-4,7-diones et benzooxazole-4,7- diones, leur preparation et leurs applications therapeutiques |
FR2877667B1 (fr) * | 2004-11-05 | 2007-03-23 | Sod Conseils Rech Applic | Derives de 4,7-dioxobenzothiazole-2-carboxamides, leur preparation et leurs applications therapeutiques |
FR2879598B1 (fr) | 2004-12-17 | 2007-03-30 | Sod Conseils Rech Applic | Inhibiteurs de phosphatases cdc25 |
FR2915747B1 (fr) * | 2007-05-04 | 2011-02-25 | Scras | Derives de tri-amino-pyrimidine comme inhibiteurs de phosphatase cdc25 |
FR2930552B1 (fr) * | 2008-04-24 | 2012-10-12 | Centre Nat Rech Scient | N-acylthiourees et n-acylurees inhibiteurs de la voie de signalisation des proteines hedgehog |
FR2945532A1 (fr) * | 2009-05-15 | 2010-11-19 | Ipsen Pharma Sas | Derives de tri-amino-pyrimidine comme inhibiteurs de phosphatases cdc25 |
RU2686323C2 (ru) | 2013-03-13 | 2019-04-25 | Форма Терапьютикс, Инк. | Новые соединения и композиции для ингибирования fasn |
EP3197446A2 (en) | 2014-09-26 | 2017-08-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Cdc25a inhibitor for the treatment of drug resistant cancer or for the prevention of tumor relapse |
TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
WO2020092395A1 (en) | 2018-10-29 | 2020-05-07 | Forma Therapeutics, Inc. | SOLID FORMS OF (4-(2-FLUORO-4-(1-METHYL-1 H-BENZO[d]IMIDAZOL-5-YL)BENZOYL) PIPERAZIN-1-YL)(1-HYDROXYCYCLOPROPYL)METHANONE |
WO2022018667A1 (en) | 2020-07-24 | 2022-01-27 | Pfizer Inc. | Combination therapies using cdk2 and cdc25a inhibitors |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1534275A (en) | 1976-01-30 | 1978-11-29 | Shell Int Research | Herbicidal compositions containing 1,4-quinones or derivatives thereof |
US5508289A (en) * | 1994-03-14 | 1996-04-16 | The United States America As Represented By The Department Of Health And Human Services | Bis-acridone chemotherapeutic derivatives |
US5523430A (en) * | 1994-04-14 | 1996-06-04 | Bristol-Myers Squibb Company | Protein farnesyl transferase inhibitors |
US6673927B2 (en) | 1996-02-16 | 2004-01-06 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Farnesyl transferase inhibitors |
IT1293525B1 (it) * | 1997-08-01 | 1999-03-01 | Uni Degli Studi Camerino | Bis-acridincarbossiammidi aventi attivita' antitumorale |
RU2298417C2 (ru) | 1999-11-09 | 2007-05-10 | Сосьете Де Консей Де Решерш Э Д`Аппликасьон Сьентифик (С.К.Р.А.С.) | Продукт, включающий ингибитор трансдукции сигналов гетеротримерных протеинов g в комбинации с другим цитостатическим средством, для терапевтического применения при лечении рака |
WO2001045680A2 (en) | 1999-12-21 | 2001-06-28 | Astrazeneca Ab | Cd45 inhibitors |
AR037714A1 (es) | 2001-12-06 | 2004-12-01 | Maxia Pharmaceuticals Inc | Derivados de tiazolidinona y oxazolidinona 2-sustituidos para la inhibicion de fosfatasas y el tratamiento de cancer |
FR2834289B1 (fr) * | 2001-12-27 | 2004-03-19 | Sod Conseils Rech Applic | Derives de benzothiazole-4,7-diones et benzooxazole-4,7- diones, leur preparation et leurs applications therapeutiques |
RU2326664C2 (ru) * | 2001-12-27 | 2008-06-20 | Сосьете Де Консей Де Решерш Э Д`Аппликасьон Сьентифик (С.К.Р.А.С.) | Производные бензотиазол-4,7-диона и бензоксазол-4,7-диона, их получение и терапевтическое применение |
FR2856688B1 (fr) * | 2003-06-25 | 2008-05-30 | Sod Conseils Rech Applic | PRODUIT COMPRENANT AU MOINS UN INHIBITEUR DE PHOSPHATASE CDc25 EN ASSOCIATION AVEC AU MOINS UN AUTRE AGENT ANTI-CANCEREUX |
FR2856686A1 (fr) * | 2003-06-25 | 2004-12-31 | Sod Conseils Rech Applic | Benzothiazole-4,7-diones et benzooxazole-4,7-diones substituees en position 5 ou 6 et leurs procedes de preparation |
FR2877667B1 (fr) | 2004-11-05 | 2007-03-23 | Sod Conseils Rech Applic | Derives de 4,7-dioxobenzothiazole-2-carboxamides, leur preparation et leurs applications therapeutiques |
FR2879598B1 (fr) | 2004-12-17 | 2007-03-30 | Sod Conseils Rech Applic | Inhibiteurs de phosphatases cdc25 |
-
2004
- 2004-12-17 FR FR0413456A patent/FR2879598B1/fr not_active Expired - Fee Related
-
2005
- 2005-12-16 US US11/722,075 patent/US8017637B2/en not_active Expired - Fee Related
- 2005-12-16 WO PCT/FR2005/003161 patent/WO2006067311A2/fr active Application Filing
- 2005-12-16 DE DE602005016014T patent/DE602005016014D1/de active Active
- 2005-12-16 ES ES05826562T patent/ES2331199T3/es active Active
- 2005-12-16 SI SI200530820T patent/SI1831209T1/sl unknown
- 2005-12-16 DK DK05826562T patent/DK1831209T3/da active
- 2005-12-16 EP EP05826562A patent/EP1831209B1/fr not_active Not-in-force
- 2005-12-16 CA CA002591215A patent/CA2591215A1/fr not_active Abandoned
- 2005-12-16 AT AT05826562T patent/ATE439359T1/de active
- 2005-12-16 PL PL05826562T patent/PL1831209T3/pl unknown
- 2005-12-16 JP JP2007546121A patent/JP2008524175A/ja active Pending
- 2005-12-16 RU RU2007127250/04A patent/RU2395510C2/ru not_active IP Right Cessation
- 2005-12-16 PT PT05826562T patent/PT1831209E/pt unknown
-
2009
- 2009-11-11 CY CY20091101174T patent/CY1109596T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2006067311A3 (fr) | 2006-08-17 |
US20090275624A1 (en) | 2009-11-05 |
PT1831209E (pt) | 2009-11-04 |
CA2591215A1 (fr) | 2006-06-29 |
CY1109596T1 (el) | 2014-08-13 |
PL1831209T3 (pl) | 2010-01-29 |
RU2395510C2 (ru) | 2010-07-27 |
ES2331199T3 (es) | 2009-12-23 |
ATE439359T1 (de) | 2009-08-15 |
DE602005016014D1 (de) | 2009-09-24 |
SI1831209T1 (sl) | 2010-01-29 |
FR2879598A1 (fr) | 2006-06-23 |
US8017637B2 (en) | 2011-09-13 |
JP2008524175A (ja) | 2008-07-10 |
RU2007127250A (ru) | 2009-01-27 |
EP1831209B1 (fr) | 2009-08-12 |
WO2006067311A2 (fr) | 2006-06-29 |
FR2879598B1 (fr) | 2007-03-30 |
EP1831209A2 (fr) | 2007-09-12 |
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