ATE486870T1 - Jnk inhibitoren - Google Patents

Jnk inhibitoren

Info

Publication number
ATE486870T1
ATE486870T1 AT06254089T AT06254089T ATE486870T1 AT E486870 T1 ATE486870 T1 AT E486870T1 AT 06254089 T AT06254089 T AT 06254089T AT 06254089 T AT06254089 T AT 06254089T AT E486870 T1 ATE486870 T1 AT E486870T1
Authority
AT
Austria
Prior art keywords
jnk inhibitors
present
compounds
apoptosis
jun
Prior art date
Application number
AT06254089T
Other languages
English (en)
Inventor
Afzal Khan
Darren P Medland
Gurpreet S Bhatia
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Application granted granted Critical
Publication of ATE486870T1 publication Critical patent/ATE486870T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
AT06254089T 2005-08-05 2006-08-03 Jnk inhibitoren ATE486870T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0516156.7A GB0516156D0 (en) 2005-08-05 2005-08-05 JNK inhibitors

Publications (1)

Publication Number Publication Date
ATE486870T1 true ATE486870T1 (de) 2010-11-15

Family

ID=34984169

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06254089T ATE486870T1 (de) 2005-08-05 2006-08-03 Jnk inhibitoren

Country Status (6)

Country Link
US (2) US7645769B2 (de)
EP (1) EP1749829B1 (de)
AT (1) ATE486870T1 (de)
DE (1) DE602006017930D1 (de)
ES (1) ES2355738T3 (de)
GB (1) GB0516156D0 (de)

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AU2009325091A1 (en) 2008-05-23 2010-06-17 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein inhibitor
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CN103492381A (zh) 2010-12-16 2014-01-01 沃泰克斯药物股份有限公司 流感病毒复制的抑制剂
AU2012214762B2 (en) 2011-02-07 2015-08-13 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
TWI558702B (zh) 2011-02-21 2016-11-21 普雷辛肯公司 醫藥活性物質的固態形式
UA118010C2 (uk) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед Інгібітори реплікації вірусів грипу
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EP2981264B1 (de) * 2013-04-02 2018-04-25 F.Hoffmann-La Roche Ag Brutons tyrosin kinase inhibitoren
CN105611920B (zh) 2013-10-12 2021-07-16 泰拉科斯萨普有限责任公司 羟基-二苯甲烷衍生物的制备
WO2015067782A1 (en) * 2013-11-08 2015-05-14 Iteos Therapeutics 4-(indol-3-yl)-pyrazole derivatives, pharmaceutical compositions and methods for use
CN105849100B (zh) 2013-11-13 2019-07-16 沃泰克斯药物股份有限公司 流感病毒复制抑制剂
RS57541B1 (sr) 2013-11-13 2018-10-31 Vertex Pharma Postupci za pripremu inhibitora replikacije virusa gripa
JP6704416B2 (ja) 2015-05-13 2020-06-03 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ インフルエンザウイルスの複製の阻害剤を調製する方法
WO2016183120A1 (en) 2015-05-13 2016-11-17 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
CN107434807A (zh) * 2017-09-20 2017-12-05 上海泓博智源医药股份有限公司 一种5‑羟基‑7‑氮杂吲哚的制备方法
CN111099625B (zh) * 2018-10-25 2021-10-01 中国石油化工股份有限公司 分子筛scm-24、其合成方法及其用途

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Also Published As

Publication number Publication date
US7645769B2 (en) 2010-01-12
EP1749829B1 (de) 2010-11-03
US20070072896A1 (en) 2007-03-29
US20100035878A1 (en) 2010-02-11
GB0516156D0 (en) 2005-09-14
ES2355738T3 (es) 2011-03-30
EP1749829A1 (de) 2007-02-07
DE602006017930D1 (de) 2010-12-16

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