DE602005012905D1 - Verwendung von Substanz P zur Mobilisierung und Proliferation mesenchymaler Stammzellen und zur Wundheilung - Google Patents
Verwendung von Substanz P zur Mobilisierung und Proliferation mesenchymaler Stammzellen und zur WundheilungInfo
- Publication number
- DE602005012905D1 DE602005012905D1 DE602005012905T DE602005012905T DE602005012905D1 DE 602005012905 D1 DE602005012905 D1 DE 602005012905D1 DE 602005012905 T DE602005012905 T DE 602005012905T DE 602005012905 T DE602005012905 T DE 602005012905T DE 602005012905 D1 DE602005012905 D1 DE 602005012905D1
- Authority
- DE
- Germany
- Prior art keywords
- mobilization
- proliferation
- substance
- stem cells
- mesenchymal stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/046—Tachykinins, e.g. eledoisins, substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020040086359A KR100593397B1 (ko) | 2004-10-27 | 2004-10-27 | 중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005012905D1 true DE602005012905D1 (de) | 2009-04-09 |
Family
ID=36013350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005012905T Active DE602005012905D1 (de) | 2004-10-27 | 2005-10-26 | Verwendung von Substanz P zur Mobilisierung und Proliferation mesenchymaler Stammzellen und zur Wundheilung |
Country Status (7)
Country | Link |
---|---|
US (2) | US8551470B2 (de) |
EP (1) | EP1658855B1 (de) |
JP (1) | JP5134772B2 (de) |
KR (1) | KR100593397B1 (de) |
CN (1) | CN1824289B (de) |
AT (1) | ATE423565T1 (de) |
DE (1) | DE602005012905D1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2007315073A1 (en) * | 2006-10-30 | 2008-05-08 | Genomix Co., Ltd. | Pharmaceuticals that promote functional regeneration of damaged tissues |
KR20080068950A (ko) * | 2007-01-22 | 2008-07-25 | 경희대학교 산학협력단 | 골수 손상 예방 및 치료용 조성물 |
US8114668B2 (en) * | 2007-05-14 | 2012-02-14 | Cardiac Pacemakers, Inc. | Composition for cold storage of stem cells |
JP2010534653A (ja) * | 2007-07-27 | 2010-11-11 | イミューンリジェン バイオサイエンシズ,インク. | サブスタンスp又はそのアナログを用いて、幹細胞の増殖又は分化を刺激するための方法及び組成物 |
KR20090035279A (ko) * | 2007-10-05 | 2009-04-09 | 경희대학교 산학협력단 | 위장관 손상 예방 및 치료용 조성물 |
US20110020291A1 (en) * | 2007-11-17 | 2011-01-27 | Debrabrata Banerjee | Use of stem cells for wound healing |
CN102076351A (zh) * | 2008-04-30 | 2011-05-25 | 吉诺米克斯股份有限公司 | 损伤组织的功能性再生促进药物 |
CA2722909A1 (en) * | 2008-04-30 | 2009-11-05 | Genomix Co., Ltd. | Method for collecting functional cells in vivo with high efficiency |
CA2722852A1 (en) | 2008-04-30 | 2009-11-05 | Genomix Co., Ltd. | Agent for recruitment of bone-marrow-derived pluripotent stem cell into peripheral circulation |
KR101175175B1 (ko) | 2008-07-28 | 2012-08-20 | 서울대학교병원 | 인간 줄기세포에서 고활성 줄기세포를 분리하는 방법 및상기 방법에 의해 분리된 고활성 줄기 세포 |
KR101590558B1 (ko) * | 2009-03-06 | 2016-02-01 | 경희대학교 산학협력단 | P 물질을 이용한 뼈 형성제 및 그 제조방법 |
EP2494977B1 (de) | 2009-10-28 | 2018-06-13 | Genomix Co., Ltd. | Geweberegenerationsförderer mit rekrutierung mesenchymaler knochenmarkstammzellen und/oder pluripotenter stammzellen in blut |
JP5852773B2 (ja) * | 2010-06-01 | 2016-02-03 | ピアス株式会社 | 骨髄間葉系幹細胞の誘引剤の製造方法、骨髄間葉系幹細胞の誘引方法、及び、骨髄間葉系幹細胞の誘引剤を製造するための使用 |
US20130089529A1 (en) * | 2010-06-11 | 2013-04-11 | University-Industry Cooperation Group Of Kyunghee University | Agent for osteogenesis using substance-p and preparation process thereof |
WO2012147470A1 (ja) | 2011-04-26 | 2012-11-01 | 株式会社ジェノミックス | 組織再生を誘導するためのペプチドとその利用 |
DK2913058T3 (en) | 2012-10-25 | 2018-02-19 | Genomix Co Ltd | Hitherto unknown method of treatment of myocardial infarction using HMGB1 fragment |
EP2913059B1 (de) | 2012-10-25 | 2018-04-11 | Genomix Co., Ltd. | Neuartiges verfahren zur behandlung von rückenmarksverletzungen mit hmgb1-fragmenten |
JP6113133B2 (ja) | 2014-11-06 | 2017-04-12 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
JP6918003B2 (ja) | 2016-01-21 | 2021-08-11 | エイビーティー ホールディング カンパニー | 創傷治癒のための幹細胞 |
KR101825041B1 (ko) * | 2016-04-07 | 2018-02-02 | 주식회사 바이오솔루션 | 물질 p를 포함하는 상처치유용 약학 조성물 |
CN110494154B (zh) | 2017-01-27 | 2023-09-29 | 斯特姆里姆有限公司 | 心肌病、陈旧性心肌梗塞及慢性心力衰竭的治疗剂 |
CN111542335A (zh) | 2017-12-01 | 2020-08-14 | 斯特姆里姆有限公司 | 炎症性肠病的治疗药 |
US11642377B2 (en) | 2018-09-27 | 2023-05-09 | Biocardia, Inc. | Bone marrow derived neurokinin-1 receptor positive (NK1R+) mesenchymal stem cells for therapeutic applications |
CN110732017B (zh) * | 2019-11-08 | 2021-08-27 | 中山大学 | Sp在制备用于治疗男性不育症的药物中的用途 |
KR102398968B1 (ko) | 2020-07-13 | 2022-05-17 | (주) 엘피스셀테라퓨틱스 | 조혈 줄기세포의 가동을 위한 물질-p의 배합 요법 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5616562A (en) * | 1990-04-27 | 1997-04-01 | Murphy; Christopher J. | Methods and compositions using substance P to promote wound healing |
US5545617A (en) * | 1993-11-12 | 1996-08-13 | The Schepens Eye Research Institute, Inc. | Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion |
US5945508A (en) * | 1996-07-23 | 1999-08-31 | Witten; Mark L. | Substance P treatment for immunostimulation |
ES2237089T3 (es) | 1998-03-13 | 2005-07-16 | Osiris Therapeutics, Inc. | Usos para celulas madre mesenquimatosas humanas no autologas. |
JP4096115B2 (ja) * | 2000-08-10 | 2008-06-04 | 輝夫 西田 | 皮膚創傷治癒促進剤 |
AU2001277767B2 (en) * | 2000-08-10 | 2006-08-31 | Teruo Nishida | Skin wound healing promoters |
AU2001297873A1 (en) | 2000-11-21 | 2003-01-02 | New England Medical Center | Novel antimicrobial compounds |
US6437093B1 (en) | 2000-11-28 | 2002-08-20 | Milkhaus Laboratory, Inc. | Methods of treatment comprising administration of Substance P |
US20040214762A1 (en) * | 2001-08-16 | 2004-10-28 | Hans-Ulrich Demuth | Use of inhibitors of proline endopeptidase to modulate inositol (1,4,5) triphosphate concentration dependent on intracellular signal cascades |
US7119071B2 (en) * | 2002-05-21 | 2006-10-10 | University Of Medicine And Dentistry Of New Jersey | Amino terminal substance P compositions and methods for using the same |
AR047712A1 (es) | 2002-09-07 | 2006-02-15 | Royal Veterinary College | Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas |
-
2004
- 2004-10-27 KR KR1020040086359A patent/KR100593397B1/ko active IP Right Grant
-
2005
- 2005-10-25 US US11/259,550 patent/US8551470B2/en active Active
- 2005-10-26 EP EP05023367A patent/EP1658855B1/de not_active Not-in-force
- 2005-10-26 DE DE602005012905T patent/DE602005012905D1/de active Active
- 2005-10-26 AT AT05023367T patent/ATE423565T1/de not_active IP Right Cessation
- 2005-10-27 CN CN2005101380225A patent/CN1824289B/zh not_active Expired - Fee Related
- 2005-10-27 JP JP2005313174A patent/JP5134772B2/ja not_active Expired - Fee Related
-
2013
- 2013-09-05 US US14/018,772 patent/US9254305B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE423565T1 (de) | 2009-03-15 |
KR20060037176A (ko) | 2006-05-03 |
CN1824289A (zh) | 2006-08-30 |
US9254305B2 (en) | 2016-02-09 |
JP2006124389A (ja) | 2006-05-18 |
KR100593397B1 (ko) | 2006-06-28 |
JP5134772B2 (ja) | 2013-01-30 |
EP1658855A2 (de) | 2006-05-24 |
US20060127373A1 (en) | 2006-06-15 |
EP1658855B1 (de) | 2009-02-25 |
US8551470B2 (en) | 2013-10-08 |
US20140065109A1 (en) | 2014-03-06 |
EP1658855A3 (de) | 2006-05-31 |
CN1824289B (zh) | 2011-08-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |