DE602005012905D1 - Verwendung von Substanz P zur Mobilisierung und Proliferation mesenchymaler Stammzellen und zur Wundheilung - Google Patents

Verwendung von Substanz P zur Mobilisierung und Proliferation mesenchymaler Stammzellen und zur Wundheilung

Info

Publication number
DE602005012905D1
DE602005012905D1 DE602005012905T DE602005012905T DE602005012905D1 DE 602005012905 D1 DE602005012905 D1 DE 602005012905D1 DE 602005012905 T DE602005012905 T DE 602005012905T DE 602005012905 T DE602005012905 T DE 602005012905T DE 602005012905 D1 DE602005012905 D1 DE 602005012905D1
Authority
DE
Germany
Prior art keywords
mobilization
proliferation
substance
stem cells
mesenchymal stem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005012905T
Other languages
English (en)
Inventor
Young Sook Son
Hyun Sook Hong
Jae Chan Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Inst Radl & Med Sciences
Industry Academic Cooperation Foundation of Chung Ang University
Korea Institute of Radiological and Medical Sciences
Original Assignee
Korea Inst Radl & Med Sciences
Industry Academic Cooperation Foundation of Chung Ang University
Korea Institute of Radiological and Medical Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Inst Radl & Med Sciences, Industry Academic Cooperation Foundation of Chung Ang University, Korea Institute of Radiological and Medical Sciences filed Critical Korea Inst Radl & Med Sciences
Publication of DE602005012905D1 publication Critical patent/DE602005012905D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/046Tachykinins, e.g. eledoisins, substance P; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE602005012905T 2004-10-27 2005-10-26 Verwendung von Substanz P zur Mobilisierung und Proliferation mesenchymaler Stammzellen und zur Wundheilung Active DE602005012905D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020040086359A KR100593397B1 (ko) 2004-10-27 2004-10-27 중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제

Publications (1)

Publication Number Publication Date
DE602005012905D1 true DE602005012905D1 (de) 2009-04-09

Family

ID=36013350

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005012905T Active DE602005012905D1 (de) 2004-10-27 2005-10-26 Verwendung von Substanz P zur Mobilisierung und Proliferation mesenchymaler Stammzellen und zur Wundheilung

Country Status (7)

Country Link
US (2) US8551470B2 (de)
EP (1) EP1658855B1 (de)
JP (1) JP5134772B2 (de)
KR (1) KR100593397B1 (de)
CN (1) CN1824289B (de)
AT (1) ATE423565T1 (de)
DE (1) DE602005012905D1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007315073A1 (en) * 2006-10-30 2008-05-08 Genomix Co., Ltd. Pharmaceuticals that promote functional regeneration of damaged tissues
KR20080068950A (ko) * 2007-01-22 2008-07-25 경희대학교 산학협력단 골수 손상 예방 및 치료용 조성물
US8114668B2 (en) * 2007-05-14 2012-02-14 Cardiac Pacemakers, Inc. Composition for cold storage of stem cells
JP2010534653A (ja) * 2007-07-27 2010-11-11 イミューンリジェン バイオサイエンシズ,インク. サブスタンスp又はそのアナログを用いて、幹細胞の増殖又は分化を刺激するための方法及び組成物
KR20090035279A (ko) * 2007-10-05 2009-04-09 경희대학교 산학협력단 위장관 손상 예방 및 치료용 조성물
US20110020291A1 (en) * 2007-11-17 2011-01-27 Debrabrata Banerjee Use of stem cells for wound healing
CN102076351A (zh) * 2008-04-30 2011-05-25 吉诺米克斯股份有限公司 损伤组织的功能性再生促进药物
CA2722909A1 (en) * 2008-04-30 2009-11-05 Genomix Co., Ltd. Method for collecting functional cells in vivo with high efficiency
CA2722852A1 (en) 2008-04-30 2009-11-05 Genomix Co., Ltd. Agent for recruitment of bone-marrow-derived pluripotent stem cell into peripheral circulation
KR101175175B1 (ko) 2008-07-28 2012-08-20 서울대학교병원 인간 줄기세포에서 고활성 줄기세포를 분리하는 방법 및상기 방법에 의해 분리된 고활성 줄기 세포
KR101590558B1 (ko) * 2009-03-06 2016-02-01 경희대학교 산학협력단 P 물질을 이용한 뼈 형성제 및 그 제조방법
EP2494977B1 (de) 2009-10-28 2018-06-13 Genomix Co., Ltd. Geweberegenerationsförderer mit rekrutierung mesenchymaler knochenmarkstammzellen und/oder pluripotenter stammzellen in blut
JP5852773B2 (ja) * 2010-06-01 2016-02-03 ピアス株式会社 骨髄間葉系幹細胞の誘引剤の製造方法、骨髄間葉系幹細胞の誘引方法、及び、骨髄間葉系幹細胞の誘引剤を製造するための使用
US20130089529A1 (en) * 2010-06-11 2013-04-11 University-Industry Cooperation Group Of Kyunghee University Agent for osteogenesis using substance-p and preparation process thereof
WO2012147470A1 (ja) 2011-04-26 2012-11-01 株式会社ジェノミックス 組織再生を誘導するためのペプチドとその利用
DK2913058T3 (en) 2012-10-25 2018-02-19 Genomix Co Ltd Hitherto unknown method of treatment of myocardial infarction using HMGB1 fragment
EP2913059B1 (de) 2012-10-25 2018-04-11 Genomix Co., Ltd. Neuartiges verfahren zur behandlung von rückenmarksverletzungen mit hmgb1-fragmenten
JP6113133B2 (ja) 2014-11-06 2017-04-12 日本メナード化粧品株式会社 幹細胞の未分化状態維持剤及び増殖促進剤
JP6918003B2 (ja) 2016-01-21 2021-08-11 エイビーティー ホールディング カンパニー 創傷治癒のための幹細胞
KR101825041B1 (ko) * 2016-04-07 2018-02-02 주식회사 바이오솔루션 물질 p를 포함하는 상처치유용 약학 조성물
CN110494154B (zh) 2017-01-27 2023-09-29 斯特姆里姆有限公司 心肌病、陈旧性心肌梗塞及慢性心力衰竭的治疗剂
CN111542335A (zh) 2017-12-01 2020-08-14 斯特姆里姆有限公司 炎症性肠病的治疗药
US11642377B2 (en) 2018-09-27 2023-05-09 Biocardia, Inc. Bone marrow derived neurokinin-1 receptor positive (NK1R+) mesenchymal stem cells for therapeutic applications
CN110732017B (zh) * 2019-11-08 2021-08-27 中山大学 Sp在制备用于治疗男性不育症的药物中的用途
KR102398968B1 (ko) 2020-07-13 2022-05-17 (주) 엘피스셀테라퓨틱스 조혈 줄기세포의 가동을 위한 물질-p의 배합 요법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616562A (en) * 1990-04-27 1997-04-01 Murphy; Christopher J. Methods and compositions using substance P to promote wound healing
US5545617A (en) * 1993-11-12 1996-08-13 The Schepens Eye Research Institute, Inc. Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion
US5945508A (en) * 1996-07-23 1999-08-31 Witten; Mark L. Substance P treatment for immunostimulation
ES2237089T3 (es) 1998-03-13 2005-07-16 Osiris Therapeutics, Inc. Usos para celulas madre mesenquimatosas humanas no autologas.
JP4096115B2 (ja) * 2000-08-10 2008-06-04 輝夫 西田 皮膚創傷治癒促進剤
AU2001277767B2 (en) * 2000-08-10 2006-08-31 Teruo Nishida Skin wound healing promoters
AU2001297873A1 (en) 2000-11-21 2003-01-02 New England Medical Center Novel antimicrobial compounds
US6437093B1 (en) 2000-11-28 2002-08-20 Milkhaus Laboratory, Inc. Methods of treatment comprising administration of Substance P
US20040214762A1 (en) * 2001-08-16 2004-10-28 Hans-Ulrich Demuth Use of inhibitors of proline endopeptidase to modulate inositol (1,4,5) triphosphate concentration dependent on intracellular signal cascades
US7119071B2 (en) * 2002-05-21 2006-10-10 University Of Medicine And Dentistry Of New Jersey Amino terminal substance P compositions and methods for using the same
AR047712A1 (es) 2002-09-07 2006-02-15 Royal Veterinary College Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas

Also Published As

Publication number Publication date
ATE423565T1 (de) 2009-03-15
KR20060037176A (ko) 2006-05-03
CN1824289A (zh) 2006-08-30
US9254305B2 (en) 2016-02-09
JP2006124389A (ja) 2006-05-18
KR100593397B1 (ko) 2006-06-28
JP5134772B2 (ja) 2013-01-30
EP1658855A2 (de) 2006-05-24
US20060127373A1 (en) 2006-06-15
EP1658855B1 (de) 2009-02-25
US8551470B2 (en) 2013-10-08
US20140065109A1 (en) 2014-03-06
EP1658855A3 (de) 2006-05-31
CN1824289B (zh) 2011-08-31

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