DE602005006465D1 - Verfahren zur Herstellung der Kristallform I von Cabergolin und Solvate davon - Google Patents

Verfahren zur Herstellung der Kristallform I von Cabergolin und Solvate davon

Info

Publication number
DE602005006465D1
DE602005006465D1 DE602005006465T DE602005006465T DE602005006465D1 DE 602005006465 D1 DE602005006465 D1 DE 602005006465D1 DE 602005006465 T DE602005006465 T DE 602005006465T DE 602005006465 T DE602005006465 T DE 602005006465T DE 602005006465 D1 DE602005006465 D1 DE 602005006465D1
Authority
DE
Germany
Prior art keywords
cabergoline
preparing
solvates
crystalline form
solvate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005006465T
Other languages
English (en)
Inventor
Alan Greenwood
Derek Mchattie
Parveen Bhatarah
Mark Gamble
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Resolution Chemicals Ltd
Original Assignee
Resolution Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32482531&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602005006465(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Resolution Chemicals Ltd filed Critical Resolution Chemicals Ltd
Publication of DE602005006465D1 publication Critical patent/DE602005006465D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Secondary Cells (AREA)
DE602005006465T 2004-04-30 2005-04-29 Verfahren zur Herstellung der Kristallform I von Cabergolin und Solvate davon Active DE602005006465D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0409785.3A GB0409785D0 (en) 2004-04-30 2004-04-30 Preparation of cabergoline

Publications (1)

Publication Number Publication Date
DE602005006465D1 true DE602005006465D1 (de) 2008-06-19

Family

ID=32482531

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005006465T Active DE602005006465D1 (de) 2004-04-30 2005-04-29 Verfahren zur Herstellung der Kristallform I von Cabergolin und Solvate davon

Country Status (18)

Country Link
US (1) US7186837B2 (de)
EP (1) EP1591445B1 (de)
JP (1) JP2007535526A (de)
AT (1) ATE394397T1 (de)
AU (1) AU2005238276B2 (de)
CA (1) CA2565440C (de)
CY (1) CY1108244T1 (de)
DE (1) DE602005006465D1 (de)
DK (1) DK1591445T3 (de)
ES (1) ES2304670T3 (de)
GB (1) GB0409785D0 (de)
HR (1) HRP20080292T3 (de)
NZ (1) NZ550925A (de)
PL (1) PL1591445T3 (de)
PT (1) PT1591445E (de)
RS (1) RS50655B (de)
SI (1) SI1591445T1 (de)
WO (1) WO2005105796A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60236600D1 (de) 2001-08-13 2010-07-15 Du Pont Substituierte 1h-dihydropyrazole, ihre herstellung und verwendung
AU2004238833A1 (en) * 2003-05-08 2004-11-25 Ivax Pharmaceuticals S.R.O. Polymorphs of cabergoline
GB0409785D0 (en) 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline
US7339060B2 (en) 2005-03-23 2008-03-04 Resolution Chemicals, Ltd. Preparation of cabergoline
GB0505965D0 (en) 2005-03-23 2005-04-27 Resolution Chemicals Ltd Preparation of cabergoline
EP1925616A1 (de) * 2006-10-26 2008-05-28 LEK Pharmaceuticals D.D. Verfahren zur Herstellung kristalliner Formen des Cabergolins via stabile Solvate des Cabergolins
EP1953157A1 (de) 2007-01-31 2008-08-06 LEK Pharmaceuticals D.D. Neue Kristallform von Cabergolin

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH535235A (de) 1970-06-19 1973-03-31 Sandoz Ag Verfahren zur Herstellung neuer reaktionsträger Lysergsäurederivate
CH535236A (de) 1970-06-19 1973-03-31 Sandoz Ag Verfahren zur Herstellung neuer reaktionsträger Lysergsäurederivate
US3920664A (en) 1972-07-21 1975-11-18 Lilly Co Eli D-2-halo-6-alkyl-8-substituted ergolines and related compounds
PH11140A (en) 1973-11-28 1977-10-27 Lilly Co Eli D-6-alkyl-2,8-disubstituted ergolines and a process for inhibiting the secretion of prolactin in mammals
CH587858A5 (de) 1973-11-28 1977-05-13 Sandoz Ag
DE2525962A1 (de) 1974-06-21 1976-01-08 Sandoz Ag Neue heterocyclische verbindungen, ihre herstellung und verwendung
US4166182A (en) 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) 1978-02-08 1979-12-25 Eli Lilly And Company 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
NL189462C (nl) 1980-04-03 1993-04-16 Erba Carlo Spa Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan.
US4526892A (en) 1981-03-03 1985-07-02 Farmitalia Carlo Erba, S.P.A. Dimethylaminoalkyl-3-(ergoline-8'βcarbonyl)-ureas
FI76085C (fi) 1981-07-21 1988-09-09 Erba Farmitalia Foerfarande foer framstaellning av ergolinderivat.
GB2103603B (en) 1981-08-11 1985-04-11 Erba Farmitalia Ergoline derivatives
US4782152A (en) 1985-08-16 1988-11-01 Eli Lilly And Company Decyanation of pergolide intermediate
GB9205439D0 (en) 1992-03-12 1992-04-22 Erba Carlo Spa Process for the synthesis of ergoline derivatives
CZ287176B6 (cs) 1997-10-03 2000-10-11 Galena A. S. Způsob přípravy ergolinových derivátů
IT1307934B1 (it) 1999-01-27 2001-11-29 Poli Ind Chimica Spa Processo per la preparazione di derivati alchimercaptometilergolinici.
GB0007307D0 (en) 2000-03-24 2000-05-17 Pharmacia & Upjohn Spa Crystalline form || of cabergoline
GB0007308D0 (en) * 2000-03-24 2000-05-17 Pharmacia & Upjohn Spa Process for preparing crystalline form | of cabergoline
GB0007309D0 (en) 2000-03-24 2000-05-17 Pharmacia & Upjohn Spa Crystalline form V|| of cabergoline
EP1507777A4 (de) 2002-03-15 2007-03-07 Pharmacia Corp Verfahren zur herstellung der kristallform i von cabergolin
US20060281777A1 (en) 2002-03-15 2006-12-14 Pfizer Inc. Process for preparing crystalline form I of cabergoline
AU2004238833A1 (en) 2003-05-08 2004-11-25 Ivax Pharmaceuticals S.R.O. Polymorphs of cabergoline
GB0409785D0 (en) 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline

Also Published As

Publication number Publication date
EP1591445A1 (de) 2005-11-02
CY1108244T1 (el) 2014-02-12
AU2005238276A1 (en) 2005-11-10
CA2565440A1 (en) 2005-11-10
US7186837B2 (en) 2007-03-06
PL1591445T3 (pl) 2008-09-30
NZ550925A (en) 2010-02-26
WO2005105796A1 (en) 2005-11-10
JP2007535526A (ja) 2007-12-06
RS50655B (sr) 2010-06-30
CA2565440C (en) 2011-09-20
ES2304670T3 (es) 2008-10-16
PT1591445E (pt) 2008-06-02
ATE394397T1 (de) 2008-05-15
EP1591445B1 (de) 2008-05-07
HRP20080292T3 (en) 2008-07-31
US20050245560A1 (en) 2005-11-03
GB0409785D0 (en) 2004-06-09
SI1591445T1 (sl) 2008-08-31
DK1591445T3 (da) 2008-08-11
AU2005238276B2 (en) 2011-08-18

Similar Documents

Publication Publication Date Title
DE602005006465D1 (de) Verfahren zur Herstellung der Kristallform I von Cabergolin und Solvate davon
ATE482966T1 (de) Verfahren zur herstellung von 7-alpha-alkylierte 19-norsteroide
DE60334995D1 (de) Verfahren zur herstellung von amorphen und keramischen stoffen mittels schmelzspinnen
NO20071702L (no) Fremgangsmate for fremstilling av 4,5-dihydro-pyrazolo[3,4-C]pyrid-oner
MXPA05003273A (es) Procedimiento para preparar inhibidores de quinazolina rho-cinasa e intermediarios de los mismos.
DE502004011239D1 (de) Verfahren zur dehydratisierung substituierter 4-dimethylamino-2-aryl-butan-2-ol-verbindungen und verfahren zur herstellung substituierter dimethyl-(3-katalyse
AR041298A1 (es) Derivados de pirrolidona como inhibidores de maob
ATE439840T1 (de) Kristalline form iii von wasserfreiem moxifloxacin-hydrochlorid und ein verfahren zu seiner herstellung
DE602005020135D1 (de) Verfahren zur veränderung der alkaloidzusammensetzung von mohnpflanzen
ATE424390T1 (de) Verfahren zur herstellung von delmopinol und derivaten davon
ATE500221T1 (de) Verfahren zur herstellung von hydroisoindolin- tachykinin-rezeptorantagonisten
HRP20050039B1 (hr) Kristalne forme olanzapina i postupci njihove priprave
ATE526332T1 (de) Verfahren zur herstellung von pentacyclischem taxan
ATE397611T1 (de) Verfahren zur herstellung von olanzapin
ATE459610T1 (de) Verfahren zur herstellung von alkenylbernsteinsäureanhydriden
ATE424892T1 (de) Verfahren zur herstellung von derivaten des 4a,5, 9,10,11,12-hexahydrobenzofuro ä3a,3,2üä 2 ü- benzazepins
ATE346084T1 (de) Zwischenprodukte und verfahren zur herstellung von heptapeptid-oxytocinanaloga
ATE456572T1 (de) Verfahren zum herstellen von lysobactin-derivaten
DE602006002650D1 (de) Verfahren zur Herstellung von Paroxetin Hydrochlorid Hemihydrat
ATE380183T1 (de) Verfahren zur herstellung von phenyltetrazolderivaten
DE602005016857D1 (de) Verfahren zur Herstellung von Tripeptid-Zwischenprodukten zur Herstellung von LHRH-Antagonisten
DE502004007177D1 (de) VERFAHREN ZUR HERSTELLUNG VON (3-OXO-2,3-DIHYDRO-1H-ISOINDOL-1-Yl)-ACETYLGUANIDIN-DERIVATEN
DE602007013426D1 (de) Verfahren zur selektiven isolierung, aufreinigung und auftrennung von monohydroxylierten 3,17-diketosteroidverbindungen
DE60308246D1 (de) Verfahren zur Herstellung von Oximen mittels Nitriten
EA200801028A1 (ru) Соли фосфоантигенов с органическими основаниями и способы их кристаллизации

Legal Events

Date Code Title Description
8363 Opposition against the patent