ATE500221T1 - Verfahren zur herstellung von hydroisoindolin- tachykinin-rezeptorantagonisten - Google Patents

Verfahren zur herstellung von hydroisoindolin- tachykinin-rezeptorantagonisten

Info

Publication number
ATE500221T1
ATE500221T1 AT06786450T AT06786450T ATE500221T1 AT E500221 T1 ATE500221 T1 AT E500221T1 AT 06786450 T AT06786450 T AT 06786450T AT 06786450 T AT06786450 T AT 06786450T AT E500221 T1 ATE500221 T1 AT E500221T1
Authority
AT
Austria
Prior art keywords
receptor antagonists
producing
tachykinin receptor
hydroisoindoline
hydroisoindoline tachykinin
Prior art date
Application number
AT06786450T
Other languages
English (en)
Inventor
Jeffrey Kuethe
Jingjun Yin
Mark Huffman
Michel Journet
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE500221T1 publication Critical patent/ATE500221T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT06786450T 2005-07-11 2006-07-07 Verfahren zur herstellung von hydroisoindolin- tachykinin-rezeptorantagonisten ATE500221T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69823705P 2005-07-11 2005-07-11
US69876105P 2005-07-13 2005-07-13
PCT/US2006/026293 WO2007008564A1 (en) 2005-07-11 2006-07-07 Process for making hydroisoindoline tachykinin receptor antagonists

Publications (1)

Publication Number Publication Date
ATE500221T1 true ATE500221T1 (de) 2011-03-15

Family

ID=37307311

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06786450T ATE500221T1 (de) 2005-07-11 2006-07-07 Verfahren zur herstellung von hydroisoindolin- tachykinin-rezeptorantagonisten

Country Status (8)

Country Link
US (2) US20100036135A1 (de)
EP (1) EP1904445B1 (de)
JP (1) JP2009500452A (de)
AT (1) ATE500221T1 (de)
AU (1) AU2006269383A1 (de)
CA (1) CA2612844A1 (de)
DE (1) DE602006020450D1 (de)
WO (1) WO2007008564A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6731684B1 (en) 1998-09-29 2004-05-04 General Instrument Corporation Method and apparatus for detecting scene changes and adjusting picture coding type in a high definition television encoder
US20100209496A1 (en) * 2006-09-06 2010-08-19 Eleni Dokou Liquid and semi-solid pharmaceutical formulations for oral administration of a substituted amide
WO2008124143A1 (en) * 2007-04-10 2008-10-16 Merck & Co., Inc. Hydroxymethyl ether hydroisoindoline tachykinin receptor antagonists
JP2016523260A (ja) 2013-06-24 2016-08-08 タイガーキャット ファーマ インコーポレイテッド そう痒におけるｎｋ−１受容体アンタゴニストのセルロピタントの使用
US8906951B1 (en) 2013-06-24 2014-12-09 Tigercat Pharma, Inc. Use of NK-1 receptor antagonists in pruritus
US9198898B2 (en) 2013-06-24 2015-12-01 Tigercat Pharma, Inc. Use of NK-1 receptor antagonists in pruritus
IL269875B2 (en) 2017-04-10 2024-06-01 Chase Therapeutics Corp NK1 antagonist combination and a method for the treatment of synucleinopathies
US11266633B2 (en) 2017-06-30 2022-03-08 Chase Therapeutics Corporation NK-1 antagonist compositions and methods for use in treating depression
EP3894394A1 (de) 2018-12-12 2021-10-20 Janssen BioPharma, Inc. Cyclobutyl-nukleosidanaloga als viruzide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002534955A (ja) 1995-10-18 2002-10-15 メルク エンド カンパニー インコーポレーテッド シクロペンチルタキキニン受容体アンタゴニスト
AR047439A1 (es) * 2004-01-27 2006-01-18 Merck & Co Inc Antagonistas del receptor hidroisoindolina taquiquinina

Also Published As

Publication number Publication date
EP1904445B1 (de) 2011-03-02
JP2009500452A (ja) 2009-01-08
US20070015923A1 (en) 2007-01-18
US7544815B2 (en) 2009-06-09
EP1904445A1 (de) 2008-04-02
US20100036135A1 (en) 2010-02-11
WO2007008564A1 (en) 2007-01-18
DE602006020450D1 (de) 2011-04-14
CA2612844A1 (en) 2007-01-18
AU2006269383A1 (en) 2007-01-18

Similar Documents

Publication Publication Date Title
ATE500221T1 (de) Verfahren zur herstellung von hydroisoindolin- tachykinin-rezeptorantagonisten
ATE480525T1 (de) Neues verfahren zur synthese von 2- aminooxazolverbindungen
EA201100748A1 (ru) Пиразиновые соединения в качестве ингибиторов фосфодиэстеразы 10
ATE507224T1 (de) Verfahren und zwischenverbindungen zur herstellung von n4-phenyl-quinazolin-4-amin derivaten
ATE425136T1 (de) Verfahren zur herstellung substituierter 3-aryl- butyl-aminverbindungen
ATE444950T1 (de) Verfahren zur herstellung von 1-amino-3,5- dimethyladamantan-hydrochlorid
ATE542818T1 (de) Imidazo- und triazolopyridinverbindungen und verfahren zu deren anwendung
ATE544754T1 (de) Verfahren zur herstellung von ivabradinhydrochlorid
EA200802054A1 (ru) Ингибиторы фермента
ATE540009T1 (de) Verfahren zur herstellung von ethylen
DE502005011170D1 (de) Verfahren zur synthese von zeolith beta mit diethylentriamin
ATE486857T1 (de) Verfahren zur herstellung von telmisartan
DE602005020661D1 (de) Neuer schaumstoffmodifikator, aus diesem neuen schaumstoffmodifikator hergestellte schaumstoffe und verfahren zur herstellung dieser schaumstoffe
ATE538095T1 (de) Verfahren zur herstellung von 2-substituierten 5- (1-alkylthio)-alkylpyridinen
DE502004011239D1 (de) Verfahren zur dehydratisierung substituierter 4-dimethylamino-2-aryl-butan-2-ol-verbindungen und verfahren zur herstellung substituierter dimethyl-(3-katalyse
IS8377A (is) Arýlindenópyridín og arýlindenópyrimidín og notkun þeirra sem mótlyf A2A viðtaka adenósíns
DE602006010400D1 (de) Olanzapin-analoga und verfahren zu ihrer verwendung
ATE548353T1 (de) Verfahren zur herstellung von substituierte n- aryl-n'-ä3-(1h-pyrazol-5-yl)phenylü-harnstoffe and intermediate davon.
ATE555131T1 (de) Verfahren zur behandlung von erkrankungen mit knochenabbau unter verwendung eines gm-csf- antagonisten
ATE447567T1 (de) Verfahren zur herstellung von tryptase- inhibitoren
ATE354583T1 (de) Verfahren zur herstellung c-7 substituierter 5- androstene
ATE445601T1 (de) Verfahren zur herstellung von carvedilol und seinen enantiomeren
DE502007002185D1 (de) Verwendung von zusammensetzungen enthaltend kappa-opioidrezeptor-antagonisten zur behandlung von dissoziativen störungen
ATE534643T1 (de) Verbessertes verfahren zur herstellung eines optisch aktiven protonenpumpenhemmers
ATE542810T1 (de) Verfahren zur herstellung von 3,5-di-omikron-acyl-2-fluor-2-c-methyl-d-ribono gamma-lacton

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties