DE602005004416D1 - Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheit - Google Patents
Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheitInfo
- Publication number
- DE602005004416D1 DE602005004416D1 DE602005004416T DE602005004416T DE602005004416D1 DE 602005004416 D1 DE602005004416 D1 DE 602005004416D1 DE 602005004416 T DE602005004416 T DE 602005004416T DE 602005004416 T DE602005004416 T DE 602005004416T DE 602005004416 D1 DE602005004416 D1 DE 602005004416D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- related compounds
- alzheimer disease
- acetic acids
- aryl acetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 title 1
- 150000001243 acetic acids Chemical class 0.000 title 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0416508.0A GB0416508D0 (en) | 2004-07-23 | 2004-07-23 | Therapeutic agents |
| GB0416508 | 2004-07-23 | ||
| PCT/GB2005/050114 WO2006008558A1 (en) | 2004-07-23 | 2005-07-19 | Arylacetic acids and related compounds for treatment of alzheimer’s disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602005004416D1 true DE602005004416D1 (de) | 2008-03-06 |
| DE602005004416T2 DE602005004416T2 (de) | 2009-01-08 |
Family
ID=32922716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005004416T Active DE602005004416T2 (de) | 2004-07-23 | 2005-07-19 | Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheit |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080300261A1 (de) |
| EP (1) | EP1773315B1 (de) |
| JP (1) | JP2008507498A (de) |
| CN (1) | CN1993120B (de) |
| AT (1) | ATE383853T1 (de) |
| AU (1) | AU2005264004A1 (de) |
| CA (1) | CA2574359A1 (de) |
| DE (1) | DE602005004416T2 (de) |
| GB (1) | GB0416508D0 (de) |
| WO (1) | WO2006008558A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1650183A1 (de) * | 2004-10-21 | 2006-04-26 | Cellzome Ag | (Benzyloxy-biphenyl)essigsäuren, ihre Derivate und Verwendung in der Therapie |
| EP1847524B1 (de) * | 2006-04-21 | 2009-10-14 | Cellzome Limited | Terphenylderivate zur Alzheimerbehandlung |
| PL1849762T3 (pl) * | 2006-04-21 | 2009-12-31 | Cellzome Ltd | Podstawione kwasy bifenylo-karboksylowe i ich pochodne |
| JP2010518064A (ja) | 2007-02-12 | 2010-05-27 | メルク・シャープ・エンド・ドーム・コーポレイション | Ａｄおよび関連状態の治療のためのピペラジン誘導体 |
| US20110040094A1 (en) * | 2007-09-14 | 2011-02-17 | Envivo Pharmaceuticals, Inc. | 1,3,4-trisubstituted benzenes |
| EA019710B1 (ru) * | 2007-10-19 | 2014-05-30 | Янссен Фармацевтика, Н.В. | ПРОИЗВОДНЫЕ 2-АРИЛ-4-МЕТИЛПЕНТАНОВОЙ КИСЛОТЫ В КАЧЕСТВЕ МОДУЛЯТОРОВ γ-СЕКРЕТАЗЫ |
| WO2009052350A1 (en) | 2007-10-19 | 2009-04-23 | Janssen Pharmaceutica, N.V. | Amine linked modulators of y-secretase |
| ES2378594T3 (es) * | 2007-10-19 | 2012-04-16 | Janssen Pharmaceutica, N.V. | Moduladores de piperidinilo y piperazinilo de la y-secretasa |
| NZ584721A (en) * | 2007-10-19 | 2011-11-25 | Janssen Pharmaceutica Nv | AMIDE LINKED MODULATORS OF gamma-SECRETASE |
| US8217064B2 (en) * | 2007-12-20 | 2012-07-10 | Envivo Pharmaceuticals, Inc. | Tetrasubstituted benzenes |
| US7968725B2 (en) * | 2008-07-22 | 2011-06-28 | Janssen Pharmaceutica N.V. | Pyridinyl modulators of γ-secretase |
| WO2010071741A1 (en) | 2008-12-16 | 2010-06-24 | Merck Sharp & Dohme Corp. | Triazole derivatives for treatment of alzheimer's disease |
| WO2010138901A1 (en) * | 2009-05-29 | 2010-12-02 | Biogen Idec Ma Inc | Carboxylic acid-containing compounds, derivatives thereof, and related methods of use |
| MX2012005281A (es) | 2009-11-05 | 2012-06-19 | Fibrostatin S L | Inhibicion de gpbp utilizando peptidomimeticos q2. |
| JPWO2011062194A1 (ja) | 2009-11-18 | 2013-04-04 | 武田薬品工業株式会社 | アミノピリジン誘導体 |
| US9802927B2 (en) | 2015-06-10 | 2017-10-31 | Denali Therapeutics, Inc. | Oxadiazine compounds and methods of use thereof |
| US10980807B2 (en) | 2016-02-09 | 2021-04-20 | Inventisbio Llc | Inhibitor of indoleamine-2,3-dioxygenase (IDO) |
| WO2023146513A1 (en) * | 2022-01-25 | 2023-08-03 | Vivace Therapeutics, Inc. | Compounds and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08325182A (ja) * | 1995-05-31 | 1996-12-10 | Fuji Yakuhin Kogyo Kk | 置換テルフェニル誘導体とそれらを含有する抗血栓剤 |
| CO4960662A1 (es) * | 1997-08-28 | 2000-09-25 | Novartis Ag | Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados |
| FR2838439B1 (fr) * | 2002-04-11 | 2005-05-20 | Sanofi Synthelabo | Derives de terphenyle, leur preparation, les compositions pharmaceutqiues en contenant |
| GB0225548D0 (en) * | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Compounds |
-
2004
- 2004-07-23 GB GBGB0416508.0A patent/GB0416508D0/en not_active Ceased
-
2005
- 2005-07-19 US US11/658,242 patent/US20080300261A1/en not_active Abandoned
- 2005-07-19 EP EP05758960A patent/EP1773315B1/de not_active Not-in-force
- 2005-07-19 CN CN2005800249403A patent/CN1993120B/zh not_active Expired - Fee Related
- 2005-07-19 CA CA002574359A patent/CA2574359A1/en not_active Abandoned
- 2005-07-19 AU AU2005264004A patent/AU2005264004A1/en not_active Abandoned
- 2005-07-19 JP JP2007522039A patent/JP2008507498A/ja not_active Withdrawn
- 2005-07-19 AT AT05758960T patent/ATE383853T1/de not_active IP Right Cessation
- 2005-07-19 WO PCT/GB2005/050114 patent/WO2006008558A1/en active IP Right Grant
- 2005-07-19 DE DE602005004416T patent/DE602005004416T2/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005004416T2 (de) | 2009-01-08 |
| CN1993120A (zh) | 2007-07-04 |
| ATE383853T1 (de) | 2008-02-15 |
| CN1993120B (zh) | 2010-05-05 |
| US20080300261A1 (en) | 2008-12-04 |
| WO2006008558A1 (en) | 2006-01-26 |
| GB0416508D0 (en) | 2004-08-25 |
| AU2005264004A1 (en) | 2006-01-26 |
| EP1773315A1 (de) | 2007-04-18 |
| CA2574359A1 (en) | 2006-01-26 |
| EP1773315B1 (de) | 2008-01-16 |
| JP2008507498A (ja) | 2008-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |