DE602004031459D1 - Verfahren zur herstellung eines medikaments - Google Patents

Verfahren zur herstellung eines medikaments

Info

Publication number
DE602004031459D1
DE602004031459D1 DE602004031459T DE602004031459T DE602004031459D1 DE 602004031459 D1 DE602004031459 D1 DE 602004031459D1 DE 602004031459 T DE602004031459 T DE 602004031459T DE 602004031459 T DE602004031459 T DE 602004031459T DE 602004031459 D1 DE602004031459 D1 DE 602004031459D1
Authority
DE
Germany
Prior art keywords
agglomerate
active ingredient
primary particles
carrier
particle size
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004031459T
Other languages
English (en)
Inventor
Zeng Xian-Ming
Kee Tee Sean
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norton Healthcare Ltd
Original Assignee
Norton Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34272843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602004031459(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Norton Healthcare Ltd filed Critical Norton Healthcare Ltd
Publication of DE602004031459D1 publication Critical patent/DE602004031459D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
DE602004031459T 2003-09-02 2004-09-01 Verfahren zur herstellung eines medikaments Active DE602004031459D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49958203P 2003-09-02 2003-09-02
PCT/US2004/028345 WO2005020963A1 (en) 2003-09-02 2004-09-01 Process for preparing a medicament

Publications (1)

Publication Number Publication Date
DE602004031459D1 true DE602004031459D1 (de) 2011-03-31

Family

ID=34272843

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004031459T Active DE602004031459D1 (de) 2003-09-02 2004-09-01 Verfahren zur herstellung eines medikaments

Country Status (12)

Country Link
US (3) US9345664B2 (de)
EP (1) EP1699434B1 (de)
AT (1) ATE498394T1 (de)
CA (1) CA2575957C (de)
CY (1) CY1113221T1 (de)
DE (1) DE602004031459D1 (de)
DK (1) DK1699434T3 (de)
ES (1) ES2362038T3 (de)
PL (1) PL1699434T3 (de)
PT (1) PT1699434E (de)
SI (1) SI1699434T1 (de)
WO (1) WO2005020963A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
MXPA05001903A (es) * 2002-08-21 2005-04-28 Norton Healthcare Ltd Composicion para inhalacion.
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
WO2005041980A1 (en) * 2003-11-03 2005-05-12 Ivax Corporation Soft steroid compositions for use in dry powder inhalers
JP2008530177A (ja) * 2005-02-16 2008-08-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗コリン作用薬及びエチプレドノールを含有する医薬組成物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
GB1569611A (en) 1976-01-23 1980-06-18 Fisons Ltd Pelletised or granular medicament formulation
US4161516A (en) 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
GB9027234D0 (en) 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
IS1796B (is) 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
IS1736B (is) 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
SE9400335D0 (sv) 1994-02-02 1994-02-02 Astra Ab Powder mixing
SA95160463B1 (ar) * 1994-12-22 2005-10-04 استرا أكتيبولاج مساحيق للاستنشاق
CA2252814A1 (en) * 1996-04-29 1997-11-06 Dura Pharmaceuticals, Inc. Methods of dry powder inhalation
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
DE10043509A1 (de) * 2000-09-01 2002-03-14 Asta Medica Ag Feste Peptidzubereitungen für die Inhalation und deren Herstellung
UA75375C2 (en) * 2000-10-12 2006-04-17 Boehringer Ingelheim Pharma Method for producing powdery preparations for inhaling
DE10141376A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Inhalationspulvern
WO2003024396A2 (en) 2001-09-17 2003-03-27 Glaxo Group Limited Dry powder medicament formulations
GB0219512D0 (en) 2002-08-21 2002-10-02 Norton Healthcare Ltd Inhalation compositions with high drug ratios
US20050158248A1 (en) 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
MXPA05001903A (es) 2002-08-21 2005-04-28 Norton Healthcare Ltd Composicion para inhalacion.

Also Published As

Publication number Publication date
WO2005020963A1 (en) 2005-03-10
US20160235678A1 (en) 2016-08-18
ES2362038T3 (es) 2011-06-27
EP1699434A1 (de) 2006-09-13
US9345664B2 (en) 2016-05-24
CA2575957C (en) 2010-11-30
DK1699434T3 (da) 2011-05-30
US9987229B2 (en) 2018-06-05
US9616024B2 (en) 2017-04-11
ATE498394T1 (de) 2011-03-15
US20170172925A1 (en) 2017-06-22
PL1699434T3 (pl) 2011-09-30
SI1699434T1 (sl) 2011-06-30
US20080131518A1 (en) 2008-06-05
EP1699434B1 (de) 2011-02-16
PT1699434E (pt) 2011-05-03
CY1113221T1 (el) 2016-04-13
CA2575957A1 (en) 2005-03-10
EP1699434A4 (de) 2009-04-29

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